Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CTNNB1 A2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
A2M KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
A2M ERAL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FZR1 ANAPC10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC10 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
EGFR APBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
PSEN1 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRKACA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NGF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRPAP1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAB2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNX17 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
TUBA1A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RANBP9 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSAP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA4A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90B1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP NGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20573181 7894075
APP F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP PLAU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP GULP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
APP DLG4 â—¼   COLOCALIZATION 2.0 0.8 intact 20573181 7894075
NTF4 BDNF â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PDIA2 CALR â—¼   COLOCALIZATION 2.0 0.8 intact 23167757 8401719
MMP14 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11381077 21385940
DLG4 CLU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DKK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15229249 10777218
TP53 DKK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
LRP1 DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
DLG4 TUBB2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
MAPK8IP2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
F8 F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0801735105 18492805
F2 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10996659 8428004
F7 F9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 2248955
F9 F7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2040636 2248955
F9 F7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2248955 12524220
SERPINC1 F9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 31030036 20080729
LRP1 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14739301
PRKCA GIPC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212824 10911369
GRIN2A LRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
HIF1A LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 21454812
HNRNPDL LCOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90B1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11861214 11290339
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
INS SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8702728 10218944
TP53 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12392301 22242153
SREBF1 LIPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22253973 15721010
LPL NME4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SKIL LRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 MDK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20811700 12883697
THBS1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11606713 10900205
PDGFB PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7691811 9739761
PDGFB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15845350 12753909
PDIA2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLAU PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721771 16189514
PRKCA SHC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7929214 12052829
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
TP53 SERPINE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SNX17 SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SKIL SNRNP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNX17 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
YWHAG TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TUBB2A TUBB2B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EGFR TUBA1A â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
LRP1 A4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 7543026 32814053 19251705 21968187 12212791
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
LRP1 SAMD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 GATB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SHC1 GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19380743 31980649
LRP1 GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SRC GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16051665 31980649
A4 A2MG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9501253 21163940
A4 HASP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBA1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBA4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TBA4A TBB4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 22939629
LRP1 ODBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TNKS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 RL23 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TBB2A TBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TBB8 TBB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22863883
LRP1 ADT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 NDKM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
INT6 LRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBB4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBB8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD44 CQ080 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 CQ080 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 NOCT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 GTPB5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GTPB5 SYHM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
RUSD3 LRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LCOR AMRP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 SYHM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SCMC2 SCMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 SCMC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 PAPD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TBB4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 KCD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 KMCP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 HASP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 SCMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 F132B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD81 APOE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
LRP1 FOXF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GCNT1 LRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 GFPT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LCOR LRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 LOXL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 NPRL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 MTO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 SENP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP1 TNKS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
TUBA1A TUBA4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
APP CALR â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
APP DAB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
A4 JIP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16301330 17719230 12893827
TBA4A TBB2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22863883 22939629 26344197
TBB2A TBB4B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22863883 22939629
SNX17 LRP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12169628
ZFP41 LRP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CTNNB1 PPARG â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MAPK8IP1 MAPK8IP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PAI1 LRP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16713569 15001579
MK LRP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10772929 16713569
DAB2 A4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32814053 11247302
KAT5 APBB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32296183 15044485 15331662 14699153 11441186 33849647 16713569 16223726 25342469 17368826
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
TUBA4A TUBB2A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
TPA CALR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9359841 16189514
JIP2 LRP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10827173
SYJ2B LRP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10827173
TBA1A TBB2A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 22939629 33961781
TPA LRP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 1502153 10632583
GRP78 A2MG â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17174955 12194978
TNKS2 AXIN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22153077 31554794
NTF3 BDNF â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 7703225
CD81 EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
SRC RXRA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17363140 10517671 15116119 15140878
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
TSP1 LRP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9045712 14991768 7775583
TSP1 MMP9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10900205 11606713
EGFR GRP78 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15657067 28065597 23956138 24189400 12471035
A4 GRP78 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32814053 30664241 33961781 33957083
LIPL LRP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 1281473 7989348 7510694
CALR A4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16189514 32814053 25241761 11378243 15896298 28106549
EGFR A4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
TBA4A TBB3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22939629 26344197
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MMP9 TIMP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 24330623 33961781
APBB1 KAT5 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
SHC1 SRC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
TPA PAI1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8607113 3090045 16713569 2110366 16189514 22449964
EGFR TBA4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24189400 16799092 23956138
LRP1 A2MG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10652313 12194978
RXRB PPARG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 22205725 25609649 15604093 30699358
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
LRP1 LRPAP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
KAT5 A4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15044485 32814053 12032152 14699153 16223726 21832049 15331662
JIP2 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16273093 31980649 25402006 24658140
TBA1A TBA4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22939629 29568061 28514442 22863883
TBA1A TBB3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27291054 22939629 29568061 28514442
APOE A2MG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9831625 21163940
CD44 SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
DAB2 SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12473651 16713569 16189514
EGFR LRP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28065597 31980649 25402006 24658140
SHC1 LRP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11854294 12789267 12069755
CTNNB1 PSEN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
APOE A4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31287614 15615705 10842709 10428074 22528093 17116874 9202294 26213366 10559559
EGFR TBA1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 25402006 24189400 16799092
LRP1 AMRP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 1374383 8703036 10747918 16101684 20030366 17326667 28514442 1718973
LRP1 APOE â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 2779654 11421580 15182176 20030366
NTF4 BDNF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 9519408 10631974 16189514 29997244
MMP9 CD44 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16631740 11872628 1707285
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
COPS5 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11707426 18926707
CTNNB1 DKK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592430 15592505
DKK1 WNT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17804805 11448771 22807036
F2 F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18492805 10350471
HIF1A TIMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10334664 15048879
HIF1A MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20631454 19285046 19950212
HIF1A TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18178340 21176881
HIF1A PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18461556 19490906 11879638
HPX LRP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15947085 496916 8424694
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
SREBF1 LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9788252 18974273 11090277
SREBF1 LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20980003
RXRB LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12551936
PPARG LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12551936
MAPK8IP2 MAPK8IP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10629060 10490659
SRC MDK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14563642 19459784 18097461
TIMP1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24330623 19010413
MMP9 TIMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24330623 19010413
RXRA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19538480
SERPINE1 PLAU â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
APP MAPK8IP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SERPINC1 F9 â—¼   CLEAVAGE ✅ - 0.9 0.9 Signor 31030036
TUBA1A TUBB2B â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
APBA2 APP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
BDNF NTF3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
DAB1 A4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 32814053 9837937 10460257 21832049
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F9 SERPINC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
F2 SERPINC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PLAT SERPINE1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
DAB1 LRP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 9837937 10827173
JIP1 LRP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20205790 10827173
CTNNB1 AXIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SERPINC1 F2 â—¼   CLEAVAGE ✅ - 0.94 0.94 Signor 31030036
DLG4 LRP1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 17360663 10827173
JIP1 JIP2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 10629060 10490659
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
BDNF NTF4 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
JIP1 A4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12917434 11517249 31413325 17719230 11724784 16301330 12893827 20205790
SHC1 A4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12485888 16189514 9045663 11877420
SHC1 EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10595738 24797263 24658140 7542744 21278788 9130710 28065597 10766863 10635327 8034616 24430869 7518560 12577067 19531499 31959764 8810340 9742218 11196191 23799367 23956138 9756944 16713569 11370743 8665853 18271526 15657067 11408594 20473329 22973453 16729043 20935677 20067773 7506413 16273093 25754235 8610109 24189400 26551075 9388490 8887653 31980649 7542991 9544989 9020193 25187647 25402006 30544639 10049786 8662998
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
SRC SHC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9388490 18840094 9710204 10482988 9096689 7499252 8939605 26551075 16189514
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
PLAU SERPINE1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
TP53 SERPINE2 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
MMP14 TIMP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
APBB1 APP â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ANAPC10 FZR1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
TUBA1A TUBB2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
APBB1 A4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 9837937 24284412 20205790 11085987 17428983 15044485 12153398 8855266 32814053 19334058 11517249 16713569 9799084 9461550 8955346 10081969 9045663 26045787 28514442 21968187 16189514 18096514 17368826 16049941 8887653 31413325 30664241 23663107 16223726 15331662
APBA2 A4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 29578633 12972431 9890987 31413325 12196555
APBB3 A4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 10081969 12153398 32814053 31413325 14527950 28514442 20205790 9461550 16189514
DLG4 GRIN2A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AXIN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SRC DAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15062102 10959835 17570479 15316068 11279201
A2M LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10652313 1702392 12194978 19026743
APP APBA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12196555 12972431 11517249 9890987
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
KAT5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21832049 12032152 16223726 14699153 15331662 15044485
AXIN1 WNT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
TNKS AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17825467 19759537 21799911 22154485 22153077
TNKS2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17825467 19759537 21799911 22154485 22153077
DAB2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 20460648 21498506 21304492 19561074 12805222 15518237 19581931 17318175
AXIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 20128690 20531388 16890161 27902311 22509369 18593713 16199882 23331499 9482734 21071413 26496610 19244247 22773187 17318191 10196136 18988627 17208333 19131971 24976009 22682247 10228155 12805222 12000790 10488109 9501208 9601641 18632848 9554852 19166851 23959799 12421363 9734785 11940574
NTF3 BDNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 7703225
NTF4 BDNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 7703225 29997244 16189514 10631974
BDNF NTF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 7703225
C3 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10608878 1060887810608870
CALR LRP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759 25351513
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
CTNNB1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
PPARG CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12021175 15190077 20303941 14764597 19075513
RXRA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12771132 25241761
PSEN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17145710 11168528 16126725 11226248 2195779 11161700 12070348 9738936 10037471 18070361 9632714 10092585 9223106 12297048 16306047 10341227 9852041
WNT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21108734 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 16554443 18936100 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 15208637 21796133
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
FZD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
CTNNB1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25721714 16847334 25168821 19495794
SRC DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24981431 16990796 14529711 18721130
DLG4 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10336672 16990796 9286858 8922396 12419528 21653829 9278515 7569905 12399578 11937501 18400955 10648730 11222640 17360663 11677266 8601796
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
PPARG EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15486348 18332871 18288266 23370527
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
YBX1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19036157 17595327 24211838 19648825 17875215 16651443
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
F8 F2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
SERPINC1 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 3800906 2013320 28743742 11927130 31030036 7238875
F8 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522143 1156094312522140 11560943
F9 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11560943 1156094312522210 12522212
WNT1 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
WNT1 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10557084 22944199 15578921 16936075 24032637
PRKCA GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9115280 8316301 11104776
SRC GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10884433 10458595 10195142 23933820 12932824 10846184 29063113 26942227 19834457 33037073 11677266 26441533 20448061
HIF1A INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14612449 11457733 18752464 17878221
HIF1A PLAUR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16956360 17335808 19177204 17357815
HIF1A SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19828020 10590062 11877282 17570486 18381294 9427542 14708599 17721610 15968405 16778202 17197388 19132225 20216986 21132271 14567996 14978738 20136501 17384280 12393531 19490965 8672239 11313255 20351105
HIF1A HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19828020 15620698
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
HSP90AA1 SHC1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 16187797 15284455 17646646 16969069 17372273 17712310
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
PPARG LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17658475 10098492 8895578 18948972
SREBF2 LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20980003 24529141 16697011
PSAP LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9707421
SRC LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12789267 11854294 18381291 21650223
PLAT LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 25879083 10632583 1502153 11560943
SERPING1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9388254
TFPI LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8824219
LRPAP1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 10747918 1718973 1374383 14596620 20030366
SERPINA1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8626456 862645615131125 15131125
PLAU LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11560943
PRKCA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15272003
MMP9 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11279011
MMP13 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10514490 10514495
SERPINE1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1500157915001570 15001579 16713569
PRKACA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12069755 19651622 11158305
SERPINC1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8626456 14596620
SERPINE2 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14596620
LTF LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1464627 15178744
MDK SHC1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15226403 18097461 16878150 17274988 16317043 11121404
PPARG MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19046432 22472882 11263774 19296842
YBX1 MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11641401 10330183 11274169 17822788
PPARG MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20021931 22472882 22207709 9665460
TP53 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17311279 15899818 17077165 18635530
PSEN1 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11518718
PDGFB SRC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 7685273 9488729 10508235 9739761
SERPINE1 PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 2110366 16713569 8607113 3090045
PLAU PLAUR â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
PLAU PLAUR â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
SERPINE1 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22449964 2544876 2161846 21199867 3090045 9184208
PLAU PLAUR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 3031025 16879932 3023326 11501527 18376415 16189514 19017363 16456079
PPARG SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10329404 15990085 18278065 14581151 17906687 17995524 10073956 16843437 11230363
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
RXRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22205725 25609649 23331499 20211142 15604093 11237216 18988627 10882139
SRC PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 30323259 10322133 26385316
PRKACA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11162439
PRKACA SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16381800
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
PRKCA PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14576165
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
PRKCA SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12052829 19651622 18669648 17924679
PRKCA PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16055440 11781100
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
RXRA SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11287605 11694526 17531980 16112614
SRC RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10322133 23331499 15140878
TP53 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 23665346 23063463 7479001 11470783 20947822
SRC SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 19901323 9388490 8939605 9096689 10971656 16497976 15592455 9121430 10891441 17389395 11687594 10329689 10482988 20068231 17570479 16189514 9685404 23109003 7516469 9927207 18840094 15688026 15212693 1409579 14963047 9710204 26551075 17016520 11075717
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785
TP53 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12609716 10719731 10101800 24195060 10029407 16406676 19826414 9833779 12719977 9017002 22028325 10224095 9849855 7521539
TP53 INS â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368