Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR DOK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
SETDB1 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PDPK1 AHCYL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635105
SIRT3 ACSS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16790548 16788062
FIP1L1 CPSF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SOX2 NTRK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22265740
SRPK1 LBR â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19674106 14701833 10390541 10049757
FIP1L1 PAPOLA â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
PPL ZNF165 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
EGFR SGPL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24189400 23956138
EPHA7 EPHA4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACOT2 ACOT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CPSF3 PAPOLA â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
EPHA4 FGFR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16365308 18790757
PPL ZNF263 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CLK3 LBR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
ZNF165 ZNF263 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
ACSS1 SIRT3 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EGFR MAST1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
CPSF1 PAPOLA â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CPSF4 CPSF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197 24981860
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
CPSF3 CPSF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26496610 24981860
SRPK1 DHX8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 23602568 34079125
SRPK2 DHX8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 33961781 26186194 23602568
SRPK2 CLK3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25416956 34133714 33961781 23602568 32707033
GEM ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BID SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ACSS2 SIRT3 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome 18680753 17923681 16788062
FGFR1 ACAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27867011
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CPSF1 CPSF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 24981860 29540792 29395067 29358758 26344197
MEOX2 PPP1CB â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
MEOX2 SLC23A1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HEXIM2 MEOX2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
MEOX2 SAT1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CPSF2 PAPOLA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CPSF2 CPSF4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ACSL3 ACSL4 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 22939629 26496610
ATP6V1B1 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
CPSF3 CPSF2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 26496610 33961781 24981860 18688255 26344197
CPSF1 CPSF2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 24981860 29395067 22939629 33469008 26344197
AHCYL1 SLC4A4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CPSF1 CPSF3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 26496610 24981860 22939629 33469008 26344197
CPSF3 CPSF4 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CPSF2 FIP1L1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CPSF3 FIP1L1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CPSF1 FIP1L1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CPSF1 CPSF3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CPSF1 CPSF2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CPSF2 CPSF3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF1 CPSF4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF4 FIP1L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CSNK1E BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11583622 12598529 20356928
CSNK1A1 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11583622 12598529 20356928
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
PDPK1 NRAS â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PDPK1 KRAS â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
SIRT3 ACSS1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 16788062 16790548 21109197 22850421
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
PDE6D KRAS â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 20418879 25550383 22179043 14561760 20416930 27791178 24725411 27410739 22721555 25759176 22002721
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196