TGFB1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23741479
12058028
|
PSMC1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RELA
|
TP53BP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8910340
8524315
|
RNF10
|
MEOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16335786
|
SMAD3
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21294585
11042172
|
SMAD3
|
DGCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21102523
|
RELA
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
12842894
5216511
|
VDR
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9553089
10330159
|
CTNNBL1
|
SPP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
MMP3
|
SPP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25545242
11375993
|
KRTAP4-11
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
VDR
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
10037600
11278756
|
LCE4A
|
SPRY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
BTK
|
TTC9C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MEOX1
|
MEOX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
KRTAP9-2
|
SPRY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
KRTAP10-5
|
KRTAP4-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
PAX3
|
MEOX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11423130
|
MEOX1
|
PAX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11423130
|
CRCT1
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
KRTAP5-6
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
CRCT1
|
KRTAP4-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
KRTAP12-4
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
FOXR1
|
KAT5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
25609649
26186194
|
FOXR1
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
KRTAP4-11
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
IKBKB
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
KRTAP4-2
|
LCE1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
KRTAP4-2
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
LCE1B
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
KRTAP10-11
|
KRTAP9-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
CPNE6
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
KAT5
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17671089
20351180
16601686
|
PAX3
|
MEOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11423130
|
EIF1AD
|
STX11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
EPM2AIP1
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
KLHL38
|
KRTAP9-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
EFEMP2
|
STK16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
KRTAP10-11
|
LCE1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
CDKN1A
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
EMD
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
CRCT1
|
KRTAP9-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
KRTAP4-2
|
KRTAP9-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
MEOX2
|
SYT17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
CRCT1
|
KRTAP4-11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
KRTAP10-11
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
HEXIM2
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
HAT1
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
KRTAP4-11
|
LCE1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
KRTAP4-11
|
KRTAP9-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
KRTAP5-6
|
LCE1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP4-2
|
KRTAP5-6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
MEOX2
|
SPRY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP5-6
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
CHIC2
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP4-2
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP5-6
|
KRTAP9-2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP12-4
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP9-2
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
PAX3
|
MEOX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
16713569
11423130
|
MEOX2
|
PAX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
16713569
11423130
|
KRTAP10-5
|
LCE1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
KRTAP4-11
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
KRTAP10-5
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
KRTAP9-2
|
MEOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
CRCT1
|
KRTAP5-6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HuRI
|
32296183
|
KRTAP9-2
|
LCE1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HuRI
|
32296183
|
LSM2
|
ZMAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
PSMC1
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
MEOX2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17074759
22206000
19383287
12842453
|
RELA
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18954936
22305266
23037503
18269916
|
VDR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17680631
23087083
16434701
21088000
|
SMAD3
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10878024
9618481
14755691
10601254
16819512
17516505
10506225
14647420
14583455
|
SMAD3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9389648
9618481
17550342
12545156
11013220
15155580
11074002
|
RELA
|
IL1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
27371733
21131967
23195252
17612514
27076634
21106671
|
BTK
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
18070982
15247281
21220427
12140561
12138165
8837778
19592497
18347055
|
TGFB1
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
11013220
11133108
12154066
12717440
12724770
12767520
12809600
14557817
15265520
15548370
16474430
17673906
17934056
18758450
18922473
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
22943793
24132110
24336330
7594497
9865696
|
TGFB1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18922473
22710166
19010789
16474430
22943793
17934056
20519943
12809600
21900405
11133108
18758450
14557817
15548370
19920116
|
TICAM2
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12721283
24812060
|
TRAF6
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16260493
15691841
15620648
15327770
10195894
16186825
16493424
17965022
10094049
10837071
|
PAX3
|
MEOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11423130
16713569
|
PAX1
|
MEOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11423130
16713569
|
TGFB1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SPP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
TGFB1
|
SMAD3
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SPP1
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
TGFB1
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SPP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
SMAD3
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26553048
27974707
10708950
19214138
|
TGFB1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21557273
24899689
24075003
24485922
28756206
32196115
|
RELA
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19385047
23195252
28148567
14600158
16365456
21255844
15051419
|
IKBKB
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
RELA
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9414129
7636192
9190901
11418664
18230685
9596659
8135780
21071440
14741709
11395507
8934574
18285351
10608823
18056447
|
RELA
|
MMP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20360864
11376631
22253074
|
IKBKB
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
135.0
|
1.0
|
Omnipath
|
15280197
17785205
27329558
22110409
22753932
22205033
21765477
15611068
18519641
15858576
25241761
33579825
23536830
28122346
19393267
34556881
24442433
14560022
15192014
21242976
16840782
19609947
33789981
10521409
26826124
21492457
19110719
23303310
16105840
22212641
26587973
34219129
15210811
16046471
11359840
27626700
15128824
28416608
17178723
21674813
17362989
28737909
19377466
15980040
16407239
15849198
20507904
26082493
15557193
34082140
21798539
26267322
29363544
12767944
20224721
26307684
12842894
17108032
26170389
24336331
27315556
31980577
11259436
34380537
20872791
21674474
15465828
15994321
17548605
26603838
16148147
25136068
33914760
26569329
22234699
17012367
14636585
22039465
32123095
15212693
27466442
33883226
15611276
22081069
19197368
17070014
20051109
26693062
14963024
33971703
28381553
33459422
27244888
18544167
18922932
20188669
15485852
20696864
22689577
17982102
20410276
15489227
|
VDR
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20713445
7705332
20227497
23644099
7981122
8119880
16195230
|
IKBKB
|
TICAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15064760
15814722
16115877
16603398
16547522
|
DOCK8
|
RHOJ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
15304341
15710388
23255595
23029280
|
PAX1
|
MEOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11423130
|