HTT
|
SAP30
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
MTA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23552838
22286760
|
MTA1
|
MTA3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
26028330
18719363
|
COP1
|
TP53
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15103385
5217012
|
TRIB3
|
COP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31125554
16794074
|
TP53
|
RECQL4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15674334
|
EP300
|
RECQL4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19299466
|
GNB2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NKX2-1
|
ABL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
MAP4K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CENPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
EPB41L3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
RIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11753601
9916993
|
PAK1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11121037
|
DDB1
|
ACTR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20855601
1008388107
|
CTNNB1
|
AHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19651607
0902132106
|
AHR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12203118
24431146
|
AHR
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15077192
10398686
|
AHR
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114727
16091746
|
MYC
|
ALB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17006931
8076602
|
TP53
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
STAT1
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19646959
|
RAD23B
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
HDAC3
|
BCL11B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219549
17245431
|
FZR1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791267
10023660
|
TP53
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19196987
0812256106
|
CTNNB1
|
BTRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15473860
10882123
|
BTRC
|
CDC25A
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
14603323
5216801
|
MYC
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CCNG1
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
CCNK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11988847
|
TP53
|
CCNK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
CCP110
|
CETN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16760425
|
SKP2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16376880
5218183
|
CDKN1A
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19541625
0812254106
|
SOX2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
|
CDKN1A
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16616141
5218511
|
DDB2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16678110
|
STAT1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17992189
|
SOX2
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22469032
22855803
|
EZH2
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18980972
21765901
|
STAT1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17992189
|
MYC
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24704206
26701207
|
DNMT1
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1375221
10417323
|
STAT1
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19061877
|
PPP5C
|
CRY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0604138103
16790549
|
PPP5C
|
CRY2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0604138103
16790549
|
DDB1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19651607
0902132106
|
SIRT1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
27776347
28583374
|
CTNNB1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24291232
24482235
|
CUL3
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CUL4B
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
DYRK1B
|
DCAF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20940704
8084776
|
DCAF7
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
INO80
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20855601
1008388107
|
XPC
|
DDB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20368362
|
TP53
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11971958
|
TP53
|
DDIT4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
19210572
|
TP53
|
DDIT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
HELLS
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17967891
|
MYC
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15616584
19786833
|
EIF3I
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
EP300
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12371907
11796223
|
MYC
|
EZH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21941025
19197161
|
FOS
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
GABARAP
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HDAC5
|
GATA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0607926103
17075044
|
HDAC3
|
GATA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0607926103
17075044
|
MYB
|
GATA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17641686
|
TP53
|
GSTK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15790310
17077087
|
HDAC3
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16847267
0510834103
|
HDAC3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22002311
18483244
|
YWHAE
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10737771
5212359
|
HDAC5
|
MEF2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10748098
15194749
|
HDAC8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220135
17721440
|
HDAC8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
26387755
17721440
|
MYC
|
HERC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11983916
|
RYBP
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SNW1
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
MAP1B
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
18656471
6700545
|
MAP2K7
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11306453
9639556
|
RPS9
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAE
|
MAP3K1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
9452471
5221876
|
MYB
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082531
|
STAT1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10637230
|
TP53
|
MYO6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16507995
20576604
|
NF2
|
SNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
PERP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
PMS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
PRKAB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRNP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24339999
19064990
|
RCHY1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5220017
17568776
|
YWHAE
|
RICTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19935711
8009452
|
RNF113A
|
SNRNP40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
SALL2
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082782
24040083
|
WDR77
|
SF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
SMU1
|
SNRNP40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
SNRNP40
|
WDR70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
SNW1
|
WDR70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
TP53
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18812399
8008642
|
TP53
|
ZDHHC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
28775165
|
APC
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
CUL4B
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ERCC6
|
SKP2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.8
|
0.8
|
PKG
|
28854368
|
MTA2
|
MTA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.8
|
STRING
|
36370105
|
SETD8
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
21035370
20932471
20932472
|
XPA
|
HELLS
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.82
|
0.81
|
PKG
|
28854368
|
SOX2
|
MTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23667531
21532573
|
MTA1
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
12920132
|
DDB1
|
AHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17392787
19651607
|
ASB4
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17636018
24337577
|
DDB1
|
BRWD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
16964240
|
UBXN7
|
BRWD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26389662
18775313
|
UBXN7
|
BRWD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26389662
18775313
|
DNMT1
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12867029
17470536
|
CBX5
|
SUZ12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27634302
20562864
|
UBXN7
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22466964
18775313
|
CUL3
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22709582
21145461
|
CUL4B
|
WDR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31155351
17041588
|
CUL4B
|
DCAF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31155351
21145461
|
SKP2
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21119685
21145461
|
DCAF7
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31753913
35016035
|
DDB1
|
MAFB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31822558
20211142
|
MYC
|
DNMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
EIF3I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
EZH2
|
HUWE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27634302
26496610
|
EZH2
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21685935
23079660
|
MYC
|
FAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
FAF2
|
HUWE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25147182
18775313
|
FOS
|
TRIB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25609649
35140242
|
WDR5
|
GRWD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29991511
17041588
|
LACC1
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
27478939
|
MED19
|
UBR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31365120
15175163
|
MYC
|
MIB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
SNW1
|
NR2C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30463901
20467437
|
SOX2
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RBBP5
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30089852
35140242
|
SOX2
|
SALL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24726434
21532573
|
SOX2
|
UBR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30894683
23667531
|
DCAF13
|
TBL3
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
WIPI2
|
BCAS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
30340022
|
CCNG1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CRY1
|
CRY2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
25756610
23133559
|
UBXN7
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22466964
31973889
18775313
|
WDR5
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33022573
31155351
17041588
|
DNMT1
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23708667
21670149
27728808
|
SIRT1
|
EP300
|
â—¼ DEACETYLATION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
19047049
|
EZH2
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27634302
24981860
27705803
|
MAFB
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23661758
20102225
|
MTA2
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11602581
24981860
12920132
|
SNW1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30415952
29467282
19818711
|
XPC
|
RAD23B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
34591642
|
WDR5
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30089852
29383478
35140242
|
HDAC5
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
SNW1
|
UBR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
SAP30
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10444591
24981860
|
DERL1
|
CFTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
26618866
16954204
16901789
18555783
|
EZH2
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27634302
23238014
|
SUZ12
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27634302
23238014
|
ETV4
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
14976201
35140242
9194565
|
SNAI1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25314079
28296173
32494626
|
FOS
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32296183
16123044
|
DNMT1
|
MTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
MTA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CDKN1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CAND1
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
DDB2
|
PPDPF
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.85
|
0.84
|
PKG
|
28854368
|
DNMT1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
MTA1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34026424
26028330
|
CUL4B
|
BRWD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31973889
26496610
31753913
|
CFTR
|
FAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
31324722
|
GPS1
|
COPS8
|
â—¼ COLOCALIZATION
|
✅
|
|
0.85
|
0.85
|
mint
|
24421388
|
CUL4B
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25189618
34026424
|
ILK
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23455922
32707033
17353931
|
EP300
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
MYC
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18483244
31155734
22002311
23079660
|
SNAI1
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25314079
34026424
21685935
|
TP53
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
12397362
5215850
|
XPC
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17154534
12486030
|
DDB2
|
SKP2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.86
|
0.85
|
PKG
|
28854368
|
EP300
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.85
|
STRING
|
36370105
|
PIN1
|
CCNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26748711
16055720
|
GATA3
|
MTA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34026424
26028330
|
MYC
|
HUWE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16269333
31677785
29467282
26279298
17314511
18488021
|
SOX2
|
PWP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
35140242
23667531
|
CDK12
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
EXO1
|
PMS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CTNNB1
|
TBL1X
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
MTA3
|
MTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21258344
24981860
26344197
|
COPS8
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CUL4B
|
GRWD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
23238014
17041588
30945288
|
CUL4B
|
SUZ12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27634302
23238014
|
WSB1
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
21145461
18187417
28514442
31253590
|
MYC
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12776737
16287840
32140074
15616592
16126174
17157259
|
XPA
|
ERCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20541997
8999876
|
FZR1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HDAC3
|
GATA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11567998
16189514
|
GATA3
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
29453984
17075044
|
SOX2
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
35140242
23667531
21532573
|
NR2C2
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21670149
12943985
|
MTA3
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21258344
24981860
26344197
|
MYC
|
WDR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31767764
35140242
17353931
29467282
30415952
27320920
|
DERL1
|
FAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
MYC
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
EP300
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
RNF113A
|
SNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BCAS3
|
WIPI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BTRC
|
SNAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CAND1
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
EIF3I
|
RPS9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CUL4B
|
DCAF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PIN1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
MTA2
|
MTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21670149
34026424
24981860
26344197
12920132
|
AHR
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17392787
21988832
10999956
|
SKP2
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18243116
22770219
26593157
|
EZH2
|
SNAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24903147
18519590
21685935
|
HDAC5
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11931768
11804585
21081666
11466315
10869435
10220385
|
ZEB2
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34026424
18182442
26028330
|
DDB2
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ERCC6
|
PRNP
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.88
|
0.88
|
PKG
|
28854368
|
SIRT1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
DCAF11
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
BTRC
|
CTNNB1
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.88
|
0.88
|
Signor
|
10228155
|
CUL4B
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
RCHY1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
HDAC5
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
ZEB2
|
MTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34026424
18182442
26028330
|
MTA1
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CUL4B
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27634302
23238014
24292684
|
DCAF7
|
RYBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
24981860
34316702
27705803
28514442
|
SLX4
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31495888
32398829
19595721
19596236
19596235
|
MYC
|
HELLS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
30415952
17314511
17353931
|
TP53
|
RCHY1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
17568776
5220017
|
TP53
|
RCHY1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.89
|
0.89
|
mint
|
17568776
5220017
|
COPS8
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
PIN1
|
ZBTB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
CDKN1A
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
CUL3
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
RGS2
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TSC22D1
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GNB2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MYC
|
ABL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21400515
23029531
19602047
|
ABL1
|
DGCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26126715
27182551
|
EP300
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12573436
10999956
|
CUL3
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21145461
21249194
22013077
16449638
22405651
26286618
12609982
|
CAND1
|
SKP2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
MYC
|
CBX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
TP53
|
CDC25A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18281511
17001315
19060337
|
CDKN1A
|
TUBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SIRT1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23474493
15130752
21719763
|
SALL2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21362508
19131967
15082782
|
ERCC6
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12732143
16916636
22118460
|
STAT1
|
DCLRE1C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
ERCC6
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12732143
16916636
22118460
|
TP53
|
DDB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16357511
19382146
|
ELK1
|
DDIT4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15751966
16008523
|
DYRK1B
|
HDAC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15546868
|
MYC
|
ELK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
EZH2
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20132185
21546904
24006445
|
STAT1
|
GSTK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
MYC
|
HDAC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
HOXD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
SNAI1
|
ILK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17587812
11244511
16357176
|
STAT1
|
INO80
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
STAT1
|
ISG15
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16009940
17312100
|
MTA2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11099047
|
MYC
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
RGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
NR1I2
|
PRKCZ
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19129222
|
PRKCZ
|
PIN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
12056906
27558335
19372727
|
TP53
|
PMS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15781865
|
TP53
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17409411
18431400
|
RIN3
|
RGS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SIRT1
|
XPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20670893
30327428
|
STAT1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24655378
14602726
|
EP300
|
MYB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CUL5
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
EP300
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
ARID4B
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
SAP30
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
DDB1
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
SNRNP40
|
SNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
CAND1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
HDAC3
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ POLYUBIQUITINATION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
12690203
|
BTRC
|
CDC25A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
ERCC6
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CDKN1B
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CTNNB1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
5218183
16376880
|
CTNNB1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CUL4B
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
EXO1
|
TERF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.94
|
0.93
|
PKG
|
28854368
|
EZH2
|
JARID2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.93
|
STRING
|
36370105
|
SUZ12
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
24981860
|
DCAF13
|
TBL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
CTNNB1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
36950384
|
CAND1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
DCAF7
|
DYRK1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
CDKN1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
DDB1
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
SIN3A
|
SAP30
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10444591
12724404
33961781
9651585
11118440
24981860
21258344
9790534
11283269
26496610
12453419
15451426
11784859
16820529
21676866
11390640
9702189
|
CUL3
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CETN2
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
SLX4
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
RAD23B
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
AHR
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
TP53
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16611888
6599495
|
COPS7B
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ARNT
|
AHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
10619402
33961781
7628454
11768231
19390533
22138065
10395741
26350169
20006590
10617682
31675361
11259609
23477502
17392787
12139968
9887096
8631989
28514442
9704006
8065341
18096572
8621524
7488247
8619634
11025203
10671489
11551916
8384309
12024042
19380484
|
SIN3A
|
SUDS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
CCNK
|
CDK12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
COPS7B
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
JARID2
|
SUZ12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
COPS8
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL4B
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ACTR5
|
INO80
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RBBP5
|
WDR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
BTRC
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EZH2
|
SUZ12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
APC
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
MTA1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
TP53
|
COP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19837670
15492238
15861129
15103385
21403399
|
TP53
|
COP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16713569
23736031
15103385
18431400
|
DYRK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
111.0
|
1.0
|
Omnipath
|
29296831
21383696
14749479
11740489
20171273
25778922
15843377
33906076
10581258
15750624
15897882
15706352
26236013
24899407
33572115
17906639
20935676
24379358
17386256
15870257
26346493
12427754
34103685
17567906
11101524
17210684
18536714
15381073
19965871
26578795
26087959
28060750
21765464
20673369
34216619
16601678
17380123
33443163
18216278
21642861
15526030
22878263
17349959
16738336
20696760
19882354
16219768
17105820
16793543
17332358
24901999
16247456
24196445
26804244
15657359
27208501
18056705
21765463
23420876
22797063
16377624
19861417
18160537
12676607
20123963
15489221
17591690
20514025
23149944
19857493
17891183
27034505
11780126
21057547
25944899
26341817
17349958
20962272
22525275
19828042
12902982
19465479
15471885
15322239
11495913
12907596
32083004
25915850
20018442
24145406
26029824
21394211
12093737
33872315
20610713
20024960
26113041
20811699
18560558
21660965
16717128
11030628
17107963
|
DYRK2
|
KATNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19287380
|
RYBP
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
8943360
|
ABL1
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8940193
17992189
20841568
|
ABL1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16099633
25164010
17618275
24465953
20841568
17318191
20840866
|
ABL1
|
MAP4K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11278340
17474147
9346925
|
ABL1
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12107171
20841568
|
ABL1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17254966
17908796
22276948
16195327
|
ABL1
|
ERCC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17626041
20841568
27827925
|
ABL1
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20841568
10866655
|
AHR
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17070097
15111621
11191113
20478272
|
AHR
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14973392
10478842
|
ARNT
|
AHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
8621524
8384309
9887096
20006590
10395741
18096572
12024042
7628454
9704006
19380484
17823304
11259609
19390533
22138065
8631989
8619634
8065341
11768231
7488247
|
MYC
|
APC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22911891
12695333
|
APC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
10545404
11166179
8259519
7890674
22083140
27902311
8638126
16212417
16798748
19061640
9286858
15327769
9482734
11533658
22056988
19576224
15327768
17318191
26496610
12628243
15355978
9065403
11712088
25241761
26910375
22682247
9065401
12000790
11707392
20219694
9707618
23840886
15525529
11251183
8628279
19631635
11972058
21664290
|
BTRC
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19847258
14603323
15340381
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
BTRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
23514615
17053147
22912335
17145710
27001857
20531388
18851830
12820959
24451375
18805092
25900982
11818547
16798748
19061640
19956254
23331499
24912152
19150432
22017875
24501426
28018973
16376880
21466614
27316454
19053519
26506240
14516475
25149538
10023660
22682247
10228155
9461217
24464578
18354482
26091241
10074433
12114015
9990852
14706645
18650423
25873176
19966869
25515538
20851351
22730322
24469040
|
DDB1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
Reactome
|
19748355
12504025
18805092
15688063
18851830
23453757
15537541
23535663
11961546
21463634
12504026
12609982
23535662
21863050
|
TP53
|
CCNG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7957050
18431400
10094833
19925028
9688532
14581561
16540664
12642871
9233778
9525742
|
TP53
|
CCNG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12556559
16713569
12642871
|
SKP2
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
MYC
|
CDC25A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8994810
10205150
11154267
9371770
14519204
15677471
17671423
|
MYC
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8425218
15121849
11602341
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
CDK12
|
POLR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
12721286
10995388
21596787
21964340
17157258
22053051
21159777
22509028
16672643
18593926
20434984
16314842
25470060
26588990
27058666
20880846
17686863
22012619
23249733
11425311
10886368
14662762
22020438
18757415
17956865
26593720
11683387
20106982
15125840
16641292
10958691
20550933
26700805
26279188
30587525
21536667
27099314
27068475
14517250
25620562
28646117
20471949
21070967
17259211
25910208
26527278
22195966
20837538
16735508
|
DNMT1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21229291
21572997
19056828
16276353
9588214
21868513
23658227
|
STAT1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20738848
11162600
12239594
16449678
21307941
22591439
10023678
10866323
|
FOS
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12705898
12087103
14755691
16141357
10891399
11789587
21864583
|
MYC
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15190211
14519204
15616584
12408868
19174556
21949397
10319992
12553001
16204065
12545156
20878079
21042278
21400515
20190815
16706751
23804320
15757889
10920185
19270520
16452181
12408820
15528212
22371483
12565816
17885207
12384701
11274368
19150257
20551174
15899785
21120446
15071503
15474507
22814619
12835716
12748190
16738884
15711923
18636159
|
TP53
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
389.0
|
1.0
|
Omnipath
|
9349504
22270849
8749722
21242964
22290440
23874636
23349794
23650552
17280505
16288208
19882681
22948151
8641969
18840648
7777546
9360984
9707425
14614448
15586362
12889596
10597242
18719376
17938176
16343438
9916993
12806965
15024021
10037739
19394332
19749793
22480684
15136035
19501055
22732402
15988033
17307334
18272192
23665236
20331637
10435630
12239594
14743206
24599959
9714336
9652736
19954840
12392301
15339933
9154806
19383287
21295542
16894028
23187802
15248906
14522900
18483411
16261158
11892838
20190809
17167174
18615633
15790310
17916908
19472317
12717415
19789303
16317118
7696178
24584189
22989750
18573881
22532570
9288775
16103882
11890931
17646389
17344317
10753197
8557703
15872011
24356969
11278953
22279545
12902982
9920903
18644983
21524151
16540664
10935506
16537920
19843844
9535786
17878219
9405685
10749849
18656471
11021966
19723072
16778363
18628250
16557594
9614553
21791610
10072388
12203124
12420214
12640112
16601686
20531308
15741235
17317670
18446786
18505818
9224526
17569660
21900401
14517211
12934105
22713239
11313928
15492238
17509529
15985438
14722112
18755897
15489892
23759594
7624148
17786325
9223430
24074410
9525742
11395510
21317932
11444825
18645021
15856024
10559267
18593586
16970927
12665570
10101800
23017582
20696891
9268733
22001409
24821728
23146670
22427654
12573582
19118657
11973611
24096481
20797428
17685229
23066038
10029406
12681065
12433990
18769160
15208672
11152513
8547219
15851483
23474493
24384472
11175333
17158927
23100276
17762884
18951877
12045203
15051477
16107883
18521083
23159636
8603071
20814747
15082782
11375890
21084835
10348346
22244155
21325288
12379483
14580351
17592775
8910340
15566940
12173040
12007564
12609999
8878553
12080472
12384701
22266868
17404570
23329847
7478511
15067082
15007388
16458891
9268365
15728246
17224908
10094833
15897882
18059034
11739748
7624134
17146435
18690848
21528307
21546904
18208621
18172861
17977830
17721438
20817677
22894933
18225552
21642427
11162600
9183012
8647846
10660101
21858218
22514644
18451802
11384995
20673369
7774811
20187950
16230382
17339230
12168779
19630958
8242752
9895308
21606339
11748232
16410722
22611192
16061648
15009091
22503977
8799837
15660129
20473858
20448457
16488074
14612423
21903579
11668476
11313463
17101782
19067706
17121856
10792001
16341121
12925527
7566157
22190353
12782287
9233781
15509808
21245169
17145718
24134839
10498892
18094076
14635196
23208500
20843368
10327058
21969549
9440695
10625687
20885946
12851404
19846554
10910098
14614455
18419600
21552844
24835508
21541551
9472102
11922774
19244234
17903248
9216067
18193090
10566557
18757425
11429705
19608464
8632901
8691637
15184659
12716906
15259070
24559687
7970699
15738655
9588214
16574813
15302882
12560513
16131836
16778203
10522058
11032828
9816111
9108440
15860260
17108107
25024194
9582019
22266186
20036872
9926942
15710329
19243472
17997002
19435914
21093383
23149933
11162506
17678435
11895854
8616838
12748190
17610896
18269916
22086179
21557991
17942917
24821727
11557753
16204065
18645003
24205274
9816061
12226108
24379401
15539944
7753560
15371422
10799578
10777217
16434701
17996705
21957244
9191059
9519881
9207798
24289924
21733196
15496412
20124454
20153576
22172947
10321740
21715977
22253232
8816885
24189165
15882981
8752276
20511722
11514734
20962589
12869419
16733561
19713748
16931520
10499591
16581545
19738071
|
DNMT3A
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20473858
15616584
16131836
24957603
|
EP300
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10362258
15509808
21858218
22000024
21245169
|
EZH2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21572997
21546904
24074410
21629038
22956625
|
DYRK1B
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15851482
29568347
16055744
|
HDAC3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9618481
17550342
12545156
15155580
22796940
22370643
16533812
17508028
|
TP53
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19922265
12897156
19597488
16616141
28433629
20066118
20457558
19749794
6396087
21163364
17371838
21900206
21340684
25241761
12897801
12748190
20182602
11896572
|
MYC
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15528212
9618481
12545156
17550342
10454538
15155580
11283613
10920185
11283614
|
SKP2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
32035614
25241761
23261596
17679094
15998794
17477906
19686743
16376880
15980415
18794347
13678583
|
TP53
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15145945
15988033
19235838
10516009
21478095
14984207
19427386
|
SKP2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
47.0
|
1.0
|
Omnipath
|
26450989
20160477
12820959
18805092
16209941
24085301
11565034
15071497
18239684
22959436
17409098
22524983
15147722
12529174
23910095
15998794
16189514
22310285
35247157
12813041
21503567
20663873
22632967
10559916
11516665
11463388
12140288
15688063
15469821
20160482
15735731
15355997
15340381
12042314
15075339
21237244
19686743
32265224
|
TP53
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21340684
20066118
20457558
20182602
6396087
|
YWHAE
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14504289
16189514
12042314
|
DYRK1B
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26307683
15010468
15546868
22711815
19887899
25476896
18818203
18636226
23528858
|
RCHY1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21236467
18006823
19445020
19459846
|
XPC
|
CETN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11900249
12648680
15703371
16697054
17884153
18199748
19809470
19847258
20211143
20457011
22615860
|
XPA
|
CETN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
XPC
|
CETN2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11900249
12648680
15703371
16697054
17884153
18199748
19809470
19847258
20211143
20457011
22615860
|
CTNNB1
|
TLE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
10485845
11934263
9819412
8955148
19460168
15768032
15121853
9118222
10080941
10831834
11713476
8756721
9751710
11136974
8757136
9488439
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
CTNNB1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21533051
19778454
16510874
12095419
17360646
18852287
15576399
19561604
20300972
19662654
15579438
17724465
9727977
24447505
18679417
12907606
|
PRKACG
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22094462
21506126
21303971
27892464
|
PIN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16713569
11533658
|
TBL1X
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11389839
25241761
20181957
33054136
18193033
|
EP300
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11050151
18987336
15806138
15060161
17410209
|
PAK1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
28007610
28423670
23543898
25639486
26547035
22369945
23162742
25472536
21822311
25225063
27713506
27910850
|
CTNNB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
16574648
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
XPA
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
DCAF7
|
DYRK1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14593110
16189514
20940704
|
XPA
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
DDB1
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
DDB1
|
DDB2
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
DDB1
|
DDIT4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB2
|
DDB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
54.0
|
1.0
|
Omnipath
|
9418871
17145710
16751180
27203177
22118460
17041588
20368362
18593899
16964240
12050362
19295130
22039351
11564863
16473935
16678110
17392787
24249678
19109893
12151405
26186194
12812979
16949367
18936169
22822215
14751237
10777491
26410533
16260596
19966799
17360488
12732143
|
XPA
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
TP53
|
DDB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12771027
22336944
15856024
12509284
12170778
16357511
12967652
15927209
11971958
|
DDB2
|
XPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15882621
22039351
19740755
29604309
23319653
|
SUZ12
|
DNMT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16357870
24074865
23326524
12435631
22466170
|
MAP2K3
|
DYRK1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17145710
12384504
11980910
|
STAT1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
10918613
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15265520
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
SIRT1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15632193
19047049
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
EP300
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19608861
29954426
18585056
15691758
10656693
25740244
|
EP300
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
137.0
|
1.0
|
Omnipath
|
11907332
25545885
21187340
10706102
16438982
10490106
19339993
15542844
23010591
11433299
19608861
17438265
17906639
16024799
9194564
20234175
23402884
12162806
26229107
16959611
15186775
9744860
11070080
17977830
17189186
22266186
20228809
15664194
19805293
25753752
11804596
26625199
27818144
10648616
16928824
9288740
10942770
12724314
23148227
23728348
15965232
19218448
16678111
16782091
20094059
14612423
24821727
10518217
16713569
9891054
25288747
17452980
14759370
19788416
25156994
18931695
22074660
23880760
15337767
15509808
26302407
22731250
18391200
16543236
19234109
21471221
23307557
25867071
12690203
15558054
18612383
23870121
18243116
19217391
22013068
16537920
16611888
18485870
9194565
12660246
9809062
23796514
11359905
12501250
15295102
19407812
25651062
23329847
16135789
|
ERCC6
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16713569
10882116
19221478
18784753
|
PMS2
|
EXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20970388
17426132
14676842
16188885
16143102
|
SNAI1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15465827
17018611
17563753
21234400
21577210
21685935
22514743
22796940
|
SNAI1
|
EZH2
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15465827
17018611
17563753
21234400
21577210
21685935
22514743
22796940
|
STAT1
|
FOS
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
TP53
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
8604347
17174366
8668332
1946467
10082525
10214938
1508692
8649776
10529369
12173040
|
STAT1
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8874187
7510676
8830676
12600988
7507205
8770944
17558387
|
FOS
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11939505
2463066
1696944
8276360
9950153
2139817
2498162
21607323
20410304
8490168
7654239
|
GATA2
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19522008
22951020
|
HDAC3
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC3
|
TBL1X
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11399519
11875494
15644117
16127449
17260466
17681149
17689680
21234400
23390297
6357187
8871614
|
HDAC3
|
SIN3A
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC3
|
TBL1X
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11399519
11875494
15644117
16127449
17260466
17681149
17689680
21234400
23390297
6357187
8871614
|
HDAC3
|
SIN3A
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC5
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10737771
10748098
11062529
12626519
|
ISG15
|
HERC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16407192
17289916
16815975
16352599
|
TP53
|
HTT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22399227
15996546
16978870
16278683
|
TP53
|
HTT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18431400
32814053
16713569
10823891
|
HUWE1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26279298
16915296
34761308
16969074
|
HUWE1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
15989956
19918835
19960022
19590512
|
PAK1
|
ILK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22521536
25738875
27642646
17420447
|
PAK1
|
MAP2K3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10661401
11062502
11385609
11907067
12885870
14764585
15536084
|
MAP3K1
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7839144
17143273
11971971
9639556
|
PAK1
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7592586
11304531
15677464
11309380
14970210
|
MAP3K1
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12738796
15170913
15592525
17462996
17496911
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
9379049
9582321
|
MAP3K1
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
10713157
19392652
18855897
9379049
26696630
17462996
12947395
18641653
23331499
23850759
12048245
11668179
21133840
21614932
21232017
12738796
9582321
24378531
22903704
11242034
10465784
15592525
17110930
26192618
9312068
17496911
11274345
15170913
|
MAP4K1
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8824585
23331499
9003777
|
PAK1
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24699410
12228228
|
MYB
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18408764
19609274
8382794
1679531
1588953
1594249
9596659
11259163
8474446
2233716
16088151
|
MYB
|
RAG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12244173
11094072
12044781
11781241
|
MYC
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
PIN1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
SKP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24259667
12963825
12769844
23792459
21245140
24177224
23277542
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
SKP2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
17145710
24259667
12963825
12769844
17157259
23277542
20852628
16376880
35260179
26038816
|
PIN1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26655473
15048125
30723410
23716601
|
PAK1
|
NF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
17081983
14580336
21481793
23162742
22105362
18071304
20068231
19036346
18669648
20302846
15378014
27285107
28090172
27345717
19165420
14981079
26555075
19651622
19691289
22567403
11719502
25893302
11782491
|
PAK1
|
SNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19379710
22595609
24556840
25084828
26004407
19923321
25472536
15833848
28423359
24168186
|
TP53
|
PERP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21451571
20019240
15856024
17344317
14707288
10733530
|
PIN1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12397362
12388558
17906639
12397361
21741598
16713569
24982848
21900206
|
XPA
|
RAD23B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
WDR5
|
RBBP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
11302744
12874027
17168535
19407509
|
WDR5
|
RBBP5
|
â—¼ SHARES_COMPLEX
|
|
|
4.0
|
1.0
|
ACSN
|
11302744
12874027
17168535
19407509
|
RCHY1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
21988832
19483087
17568776
24367557
25116336
21084285
12654245
21791603
20452352
19043414
16713569
31630802
27519799
19918835
|
SNAI1
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
14673164
15465827
17018611
17563753
21234400
21577210
22514743
22796940
|
SNAI1
|
SIN3A
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
14673164
15465827
17018611
17563753
21234400
21577210
22514743
22796940
|
SIRT1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
18235502
11672523
18235501
15205477
35931247
15989956
17964266
25280219
19047049
16713569
19960022
21245319
12006491
19590512
|
TP53
|
XPC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12771027
22336944
12242345
23050045
16357511
12967652
15927209
|
TP53
|
XPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
12771027
9346961
10779360
21340684
19004803
10367887
20066118
12496474
12242345
20457558
20182602
10962562
6396087
9892649
12967652
|
ERCC6
|
ERCC6
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.24
|
1.23
|
PKG
|
28854368
|
RECQL4
|
DTL
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.31
|
1.3
|
PKG
|
28854368
|
XPA
|
PPDPF
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.51
|
1.5
|
PKG
|
28854368
|
RECQL4
|
RECQL4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.61
|
2.61
|
PKG
|
28854368
|
XPC
|
XPC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.23
|
3.22
|
PKG
|
28854368
|
TP53
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.51
|
3.5
|
PKG
|
28854368
|
XPC
|
HIST1H1A
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.58
|
3.57
|
PKG
|
28854368
|
DDB2
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.71
|
5.7
|
PKG
|
28854368
|