Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CENPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 EPB41L3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11753601 9916993
PAK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11121037
DDB1 ACTR5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20855601 1008388107
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCNG1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CCNK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11988847
TP53 CCNK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
BTRC CDC25A â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 14603323 5216801
MCM10 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
SKP2 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16376880 5218183
PCNA CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
AHR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12203118 24431146
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
STAT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17992189
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
AHR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15077192 10398686
EZH2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980972 21765901
STAT1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17992189
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
CCP110 CETN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16760425
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
UCHL1 COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP5C CRY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0604138103 16790549
INO80 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20855601 1008388107
DDB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
DDB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
XPC DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
XRCC5 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
DYRK1B DCAF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20940704 8084776
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
EP300 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12371907 11796223
FOS MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10348347 12173040
AHR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114727 16091746
MYC ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17006931 8076602
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
MYC DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15616584 19786833
MYC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9988278
TP53 MYO6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16507995 20576604
TP53 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
PPP5C CRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0604138103 16790549
RAD23B ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SNW1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
EZH2 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980680 17584191
SUV39H1 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
ZEB2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19424592 12837246
UCHL1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
TP53 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19196987 0812256106
TP53 PRKAB1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 GSTK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15790310 17077087
TP53 ZDHHC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28775165
TP53 PRNP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24339999 19064990
TP53 MTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23552838 22286760
COP1 TP53 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 15103385 5217012
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 PERP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
MAP3K1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008162 10465784
TRAF6 NR2C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14633987
TRAF6 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20501938
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
LRRK2 DYRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
BECN1 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRMT5 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TRIB3 COP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31125554 16794074
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
STAT1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19646959
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
RCHY1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16914734
HDAC3 BCL11B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219549 17245431
HDAC3 GATA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607926103 17075044
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS9 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP2K7 MAP3K1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11306453 9639556
ESR1 MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15556606 5217326
LRRK2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
LRRK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
UCHL1 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219675 17318178
NEDD8 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRMT5 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNMT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1375221 10417323
GNB2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR61 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCAF7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF3I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SAP30 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP1 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
HELLS DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17967891
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 BCAS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17505058 16617102
ESR1 MTA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15169784
MTA1 MTA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26028330 18719363
TBL3 USP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WDR61 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WSB2 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WDR77 SF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NR2C2 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11844790
MYB GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
COPS8 NEDD8 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
APC BTRC â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DDB1 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34026424 25189618 24249678 26679995
DDB1 MUS81 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 27354282 24412650
SETD8 DTL â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21035370 20932472 20932471
DTL CDT1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21930785 30623174 24906324 26272819
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
HUWE1 PCNA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25147182 22203964 27146073
DNMT1 CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17470536 12867029
CBX5 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 28225217
CUL4B WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
CUL4B DCAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31155351
SKP2 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 21119685
ASB4 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17636018 24337577
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
DCAF7 DDA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31155351 27173435
WSB2 DDA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TRAF6 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 25499913
WDR26 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29911972 17041588
SHC1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
CUL1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22474075
ESR2 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 25604459
BECN1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25499913 23974797
EED DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23238014 17041588
DDB1 BRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 16964240
DDB1 AHR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19651607 17392787
DDB1 MBD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 34026424
DDB1 MAFB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31822558 20211142
DCAF7 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35016035 31753913
FAF2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25147182 18775313
ESR1 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
EZH2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
MYC MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MBD3 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
MYC EIF3I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC FAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
PAK1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16452229 12374744
ESR1 SNW1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19934264 33731348
SNW1 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 28302793
SNW1 NR2C2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30463901 20467437
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
WDR5 GRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29991511 17041588
UBXN7 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
UBXN7 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
UBXN7 BRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 BRWD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 25123934
EZH2 HDAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23079660 21685935
SKP2 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6540196 18239684
CDT1 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30018425 12840033
LRRK2 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
NEDD8 DCAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
FOS TRIB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 25609649
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
CAND1 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 21145461
ESR2 EIF3I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 15604093
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
EZH2 WDR61 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 16169070
RBM39 SMU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
SHC1 ABL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8112292 19380743 10194451
CCNG1 CUL4B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CRY1 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25756610 34237211 17463251 33961781
CRY1 CRY2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 23133559 25756610
UBXN7 CUL4B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22466964 18775313 31973889
DDA1 DDB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20562859 33961781 26496610
WDR5 DDB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31155351 33022573 17041588
DDB1 NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 18274552 16964240 21145461 18247557
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
SNAI1 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20385133 22128911 34040386
SNW1 MYC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30415952 19818711 29467282
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
TRAF6 UCHL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23717208 17353931 32814053
HDAC1 ZBTB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33301849 26496610 33961781
UBXN1 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34237211 28152074 18775313
MAFB FOS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
FOS DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 35140242 33961781 26186194
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BECN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 MTA1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EZH2 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23238014 27634302
SUZ12 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23238014 27634302
CDT1 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22451935 15448697
ETV4 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9194565 14976201 35140242
SNAI1 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28296173 25314079 32494626
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
MYC TERT â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32140074 28628118 28205554
FOS PIN1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16123044 32296183
ESR1 GRWD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
RBM39 ESR2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11704680
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DNMT1 MTA1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PCNA POLE â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
MTA1 TP53 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCNG1 MDM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12556559
GPS1 COPS8 â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 24421388
DET1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 16949367 31973889
MTA1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 26028330
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B BRWD3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31753913 26496610 31973889
ILK DDB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 17353931 23455922
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
ESR1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
SNAI1 HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25314079 21685935
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
TRAF6 UBXN7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
XPC XPA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17154534 12486030
CFTR XRCC5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
UBXN7 NEDD8 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24076655 22466964 22537386
LRRK2 PAK6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24510904 24947832 26375402
NEDD8 AHR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12215427
CFTR FAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
TRIB1 DET1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
COPS3 NEDD8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CDT1 DTL â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CUL4B DDA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
PIN1 CCNK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16055720 26748711
COPS3 DCAF4 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
LRRK2 DDB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
MYC HUWE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17314511 16269333 26279298 18488021 29467282 31677785
MDM2 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20708156 24804778
ESR1 STAT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25303530 31527615
ZEB2 MBD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34026424 26028330
HDAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31527615 16469706 14722073 26487511 20348541
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
EIF3I ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10706629 31527615
GATA3 MTA3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34026424 26028330
CTNNB1 TBL1X â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CUL4B GRWD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 30945288 17041588
CUL4B SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 27634302
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
CUL5 WSB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
DET1 DDA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19295130 17452440 33961781
DDB2 XPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22039351 23319653 28760956 27203177 29604309 15882621
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
MYC RBM39 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
HDAC1 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 27705803 33961781 26186194 33022573 22689669
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
GATA3 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29453984 17075044
NR2C2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12943985 21670149
HDAC3 GATA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11567998
DNMT1 MTA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27728808 26344197 21670149 23708667
ESR1 MTA3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18451880 31527615
MTA3 MTA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21258344 24981860 26344197
COPS7A DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS8 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDT1 SKP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC SKP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
COPS2 DDB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC1 SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BTRC SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EIF3I RPS9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
COPS3 DDB2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CDC25A CUL1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
DDA1 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31973889 26496610 21145461 19295130 16949367
DCAF4 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 21145461 30945288 16949367 32140073
DCAF8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33288900 33961781 31155351 21145461 16949367
CUL4B DTL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 31973889 24962565 23555860 16861906 26496610 33961781 31155351 21145461 16949367
DDB1 DDA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20562859 17609381 17452440 16964240 26344197 19295130 16949367
AHR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10999956 17392787 21988832
SKP2 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22770219 18243116 26593157
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
EP300 RORA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9862959 16713569
EP300 MEF2A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12371907 20590529
PMS2 PCNA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15225546 28439008 17148452
EZH2 SNAI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 24903147 18519590
ZEB2 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34026424 18182442 26028330
DNMT1 EED â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16357870 22094255
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COPS2 NEDD8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
COPS3 DDB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 CUL4B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BTRC NEDD8 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CCNK CDK12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26659056 32804079 26344197 22939629 26748711
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
DET1 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33911083 33961781 31155351 17452440 16964240 14739464 16949367
DCAF8 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32703400 31257023 32235678 33288900 31391242 19966799 33961781 24500646 31155351 16964240 19295130 16949367
DDB1 DCAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19966799 33961781 16964240 30945288 16949367
DDB1 DTL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21628527 17041588 23478441 16861906 29424068 30623174 33961781 31155351 30649446 16964240 33536335 16949367
SLX4 EME1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19596236 19596235 32398829 31495888 19595721
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MYC HELLS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 17314511 30415952
MYC SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23277542 12769844 12963825 26038816 17157259 24259667
SNAI1 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21685935 26794444 25314079 20562920 23011797 14673164 34026424
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
SETD8 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18319261 22556262 26666832 21035370 27462463 18166648
PCNA DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20940144 20613874 24958773 9302295 26496610 30301766 12354094 23708667 22606318 10888872
RYBP WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 26186194
ZEB2 MTA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34026424 18182442 26028330
GATA3 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29453984 34026424 26028330 31409898
HDAC1 MTA3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12705869 23752268 28514442 34026424 22075476 26028330 26496610 21258344 33961781 24981860 18451879 26344197
CDT1 GRWD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25990725 18162579
DNMT1 EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31130994 16357870 22094255 28068325 21378168
AHR ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15837795 19460354 12612060 27420286 17392787 10620335 9611253
MBD3 MTA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25123934 26028330 22196727 24981860 21670149 26344197
MTA3 MBD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12705869 25123934 26028330 21258344 24981860 26344197
DCAF7 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 33961781 24981860
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PIN1 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS8 CUL4B â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDKN1A SKP2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ABL1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16702947 25624478 12110584
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ABL1 DGCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26126715 27182551
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
TP53 CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18281511 17001315 19060337
GNB2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A TUBB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A NRBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19487281 14729654 23907131
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
CETN2 XPC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21962512 17154534 28514442 11279143 26638075 27880911 28760956 33961781 22939629
NR1I2 COPS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
STAT1 DCLRE1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
DDB1 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22118460 28035050 12050362 24249678 26410533 22822215 28416769 29262658 16473935 18593899 30923324 16678110 16964240 20368362 12812979 19295130 16751180 19109893 17360488 16260596 27203177 17392787 10777491 12151405 32985517 14751237 22039351 17041588 12732143 11564863 9418871 19966799 33961781 26186194 34251884 16949367
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
PCNA DTL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25154416 21725088 16861906 29424068 30301766 30623174 20129063
EME1 MUS81 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19596236 28514442 16189514 25224045 27354282 24733841 25319828 21962513 29738624 19017809 33961781 28575661 14617801 12686547 12721304 17289582 19363487 18413719
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12573436 10999956
STAT1 INO80 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
STAT1 ISG15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16009940 17312100
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
SLX4 MUS81 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25416956 29850896 25224045 21516116 23623386 22902628 25533185 32296183 23033263 19596235 31495888 23093618 21240275 19596236 23994477 29892012 32398829 24012755 19595721
NR1I2 MUS81 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC PIN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26655473 29467282 15048125 19131971
MYC SLBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HOXD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC ELK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC RGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBM39 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
TP53 PMS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781865
SNAI1 ILK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17587812 11244511 16357176
TERT CTNNB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
TP53 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17409411 18431400
PIN1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15175157 16713569
TRAF6 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18093978
BECN1 UVRAG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29313410 19270696 21597469 25275521 32097085 22314358 24956373 23954414 25533187 34386498 32296183 20562859 22081109 18641390 26496610 27621469 31373534 23878393 19270693 24056303 27203177 33977871 24034250 19372752 30686098 30258449 22493499 24879154 25490155 19050071 29866835 18843052
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
CDT1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407242 30018425 24423875 16861906 16482215 18162579 26272819 16362051 30301766 30623174 16407252 21930785
RGS2 LIG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCZ PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SHC1 ILK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SHC1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
RBP1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11313948 10995764 12242309
STAT1 GSTK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MBD3 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10444591 21258344 11102443 12354758 19041848 27068747 26496610 25123934 24048479 21670149 17827154 22939629 23752268 12124384 16428440 33961781 24981860 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
MTA1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 27098840 21258344 33264408 9885572 26028330 26496610 14722073 20585571 21670149 22939629 18451879 34026424 23752268 29997244 16511565 26949739 10840944 33961781 11146623 24981860 17922035 12920132 26344197
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
HDAC3 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 10809664 28348241 11931768 10944117 18202150 21258344 16980585
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CUL1 SKP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 17704768 12840033 18667692 15456869 18239684 12504026 9636170 12609982 17439941 21145461 10559858 9736735 17438373 23951410 19398581 28614300 22464731 22013077 29137415 30349055 19270694 16774918 18173839 23770852 24085301 21249194 29499133 23868976 22310285 11961546 9430629 32313199 10559916 25143387 20160477 10230406 9663463 22524983 34237211 21119685 33422522 27542266 29103612 16880511
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CDT1 SKP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12840033 15004027 18162579 26496610 31160578 15855168 14993212
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
CAND1 SKP2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
ESR2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20155458 10037443
NR1I2 PRKCZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
RBM39 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21182205 33731348 11704680 15694343
MTA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16807247 31527615 12167865 12639951 11146623 18451880
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
RIN3 RGS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GATA3 TET2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 SUDS3 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 SAP30 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
EP300 MEF2A â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
TRAF6 IRAK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18347055
COPS2 CUL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613464 18451879
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
DDB1 GPS1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
SNRNP40 SNW1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
MUS81 SLX4 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
BTRC CDC25A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
COPS2 CUL3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CDKN1B SKP2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
CUL4B DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
DDB1 DET1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HDAC1 MTA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD3 MTA1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD3 MTA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EZH2 JARID2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CDKN1A PCNA â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
PCNA SETD8 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
GPS1 NEDD8 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
DCAF4 DDB1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DCAF13 TBL3 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
IRAK1 TRAF6 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
DCAF7 DYRK1B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CUL1 GPS1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
DDB1 DTL â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
TRAF6 IRAK1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22033459 24735611 11397809 19716405 17197697 30872404 8837778 10346818 17785851 11960013 18234474 16951688 16024789 11287640 12034707 21220427 23381138 19166926 24434549 28882891 18056395 11259596 23244239 12496252 22447928 20043910 12566447 11518704 12242293 10920205 10383454 18347055 9374458 31921110 14625308
SAP30 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11390640 16820529 10444591 21258344 9651585 9885572 15235594 26496610 11283269 18193082 11784859 23752268 16713569 9790534 33961781 12788099 11118440 15451426
EED HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581039 11124122 26496610 22439931
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
EED SUZ12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 29379173 27338022 19026780 26496610 35016035 27634302 15385962 15225548 18285464 20543829 12435631 31786184 24457600 31281901 20075857 19026781 21078963 27705803 22439931 28320739 33961781 24981860 23280602 18483221
EED EZH2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21135039 9584197 9742080 31948940 29379173 27338022 18931660 28068325 33754075 11158321 9584199 32296183 22897849 17937919 19026780 21190999 26496610 24320048 33849069 27634302 15385962 16314526 29669287 15225548 18285464 10581039 21123648 12435631 31786184 23624935 24457600 20075857 15882624 19026781 21078963 22094255 22439931 28320739 27705803 31527584 24981860 33961781 23280602 26344197
DTL PCNA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CUL3 GPS1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BECN1 UVRAG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CETN2 XPC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DNMT1 PCNA â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
EED JARID2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
COPS7B COPS8 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
MDM2 TP73 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LIG1 PCNA â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS7A COPS8 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDT1 PCNA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
COPS2 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
RBBP5 WDR5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 31544921 17925232 16253997 20305087 15960975 30089852 21531708 21220120 15199122 17178841 25666610 31685992 15960974 27320920 23508102 21884981 32076268 33022573 16878130 28813667 17041588 31076518 17500065 19556245 27705803 24981860 33961781 16603732 26186194 31400120
ARNT AHR â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8065341 28514442 11768231 9704006 11259609 7488247 19380484 20006590 22138065 11025203 10617682 23477502 9887096 31675361 12024042 12139968 11551916 17392787 18096572 8384309 10619402 7628454 19390533 26350169 8631989 8621524 10671489 33961781 10395741 8619634
DDA1 DDB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCNK CDK12 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS3 COPS7B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS7B GPS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS2 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
JARID2 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS2 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS7A GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS8 GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ACTR5 INO80 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RYBP ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 8943360
ABL1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 23318434 10391235 21188172 25666857 20841568 11278685 23331499 27294865 25893286 21199784 17535448 21051857 10391250 18988627 10391249 28690977 25341038 19788416 26512706 10391251 20195489 12070014 15459660 20057499 15686624 21435002 11223036
ABL1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20841568 10866655
ABL1 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11278340 17474147 9346925
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17254966 17908796 22276948 16195327
ABL1 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12107171 20841568
ABL1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8940193 17992189 20841568
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10837221 20841568
ABL1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8617726 1623525 10194451 19380743 10592173 20841568 8112292
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 RBM39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27018250
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
APC NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
MYC APC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22911891 12695333
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
TP53 CCNG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7957050 18431400 10094833 19925028 9688532 14581561 16540664 12642871 9233778 9525742
TP53 CCNG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12556559 16713569 12642871
CUL1 CDC25A â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP2 CDC25A â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
MYC CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8994810 10205150 11154267 9371770 14519204 15677471 17671423
BTRC CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19847258 14603323 15340381 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
MYC CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
FOS CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12705898 12087103 14755691 16141357 10891399 11789587 21864583
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
DNMT3A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20473858 15616584 16131836 24957603
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
STAT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20738848 11162600 12239594 16449678 21307941 22591439 10023678 10866323
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
DNMT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21229291 21572997 19056828 16276353 9588214 21868513 23658227
TP73 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10435630 15790310 11172610 17611664 12934105 18421303 21245298 18418051 12841870 14614455 12639967 10207112 17700533 18644986 18951877 19067706 16193303 12676926
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
SKP2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 32035614 25241761 23261596 17679094 15998794 17477906 19686743 16376880 15980415 18794347 13678583
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
HDAC3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9618481 17550342 12545156 15155580 22796940 22370643 16533812 17508028
DYRK1B CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15851482 29568347 16055744
CDKN1A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 23443559 25411249 20606006 8868473 15576034 16474839 25416956 20605778 16510448 18703516 23139781 11302688 11254741 26272819 16616141 21988832 11313979 7780738 17588519 12964161 25502805 10022118 8861913 16189514 26496610 16082198 8861969 17129767 18263614 26186194 22383522 22911014 7915843 7911228 27107012 23223023 17115032 32296183 19895794 18794347 19704162 10873631 9546435 8662825 31515488 21415862 9545252 11350925 12930846
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
CUL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15340381 15147722 12820959 12835716 11961546 11516665 15071497 15688063
RCHY1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21236467 18006823 19445020 19459846
SKP2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 47.0 1.0 Omnipath 26450989 20160477 12820959 18805092 16209941 24085301 11565034 15071497 18239684 22959436 17409098 22524983 15147722 12529174 23910095 15998794 16189514 22310285 35247157 12813041 21503567 20663873 22632967 10559916 11516665 11463388 12140288 15688063 15469821 20160482 15735731 15355997 15340381 12042314 15075339 21237244 19686743 32265224
DYRK1B CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26307683 15010468 15546868 22711815 19887899 25476896 18818203 18636226 23528858
XPA CETN2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
XPC CETN2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
XPC CETN2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
XPA CUL4B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
XRCC5 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
PCNA DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
XPA DDB1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CAND1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 21463634 12504026 12609982 23535662 21863050
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
XPA DDB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
PCNA DTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
DCAF7 DYRK1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14593110 16189514 20940704
MAP2K3 DYRK1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 12384504 11980910
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
STAT1 EP300 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 EP300 â—¼   PROTEIN_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
ISG15 HERC5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16407192 17289916 16815975 16352599
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
TP73 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20921405 15734740 20156675 10469568 11245471 10207051
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
PAK6 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 11960368 11923280 18467333 22349818 23132866 11504915 11715018 28196907
MDM2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18499675 17700533 26025930 25417702 19218448 21088494 10321734 10469568 10435614 20588255 25301064 10207051 11223036 21261729
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 76.0 1.0 Omnipath 16287840 15655249 12821782 16880523 21807113 19047367 14744757 16489011 12941894 10786671 14519204 19360348 10723141 12970752 15595642 18365874 15665468 22207128 14611815 10022128 15226182 11274400 10491298 11606399 17070091 19787269 19806010 20454512 19762557 21132266 21553143 18818322 10914736 17934056 19148473 11435602 12695333 12802280 21995449 11287602 12044867 21627565 23860446 17942561 19649288 23759068 10606235 12807729 15958520 17141225 20723213 16402390 16785237 18093727 21855630 24705139 18367227 14563552 16205635 19003324 9988278 17706770 17967894 18226852 18754863 10637317 18586674 14612409 19912441 15371341 11916966 12646176 11279234 18158869
MYC SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24259667 12963825 12769844 23792459 21245140 24177224 23277542
SKP2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 24259667 12963825 12769844 17157259 23277542 20852628 16376880 35260179 26038816
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
MTA1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
SHC1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PAK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10661401 11062502 11385609 11907067 12885870 14764585 15536084
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
PAK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18521086 26944939 16778166 18755239 21893191 15178330 19205871 29548483 26554417 27003261 24505617 16452229 15193262 19557173 15642175 12374744 19465939 17604944 25447917 20179234
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PAK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7592586 11304531 15677464 11309380 14970210
PAK1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24699410 12228228
PAK1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19379710 22595609 24556840 25084828 26004407 19923321 25472536 15833848 28423359 24168186
PMS2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18768816
XPA RAD23B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SNAI1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
TP53 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15656906 12807729 15067344 15734740 11064449 15262117 16234237 10778946 15371422 22496369 18754863 19649288 19787269
TP73 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15734740 22496369 16234237 16205639
ESR1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21411498 12122114 21693539 18519947 16690106 10805720 19360348 23409030 18754863
ESR2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12122114 10805720
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
AHR TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17070097 15111621 11191113 20478272
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
TP53 COP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19837670 15492238 15861129 15103385 21403399
TP53 PERP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21451571 20019240 15856024 17344317 14707288 10733530
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
GRK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27326393 15053879 22223642 20124405 26029824 26226012
TP53 COP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16713569 23736031 15103385 18431400
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
TRAF6 IRAK1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
IRAK1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 10346818 17145710 17785851 16024789 14625308 11259596 10383454 18234474 9374458 11287640 23244239 21220427 11518704 19166926 16951367 15894263 10747026 35926385 18056395 12566447 12496252 22447928 12242293 8837778 10920205 11960013 19716405 24735611 20043910 24434549 17785432 11397809 18347055 22033459 12140561 23381138 17197697
UVRAG BECN1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 10604474 10949026 11085534 11704864 12667443 16179260 16227588 17106237 17446862 17891140 18097445 18612260 19265852 22039431 22093031 22166994 22421439 22836101 22885520 23030059 23064052 23301705 23377657 23430059 23725295 23850759 24070470 27754749 28645028 8929532 9765397
UVRAG BECN1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 10604474 10949026 11085534 11704864 12667443 16179260 16227588 17106237 17446862 17891140 18097445 18612260 19265852 22039431 22093031 22166994 22421439 22836101 22885520 23030059 23064052 23301705 23377657 23430059 23725295 23850759 24070470 27754749 28645028 8929532 9765397
UVRAG BECN1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10604474 10949026 11085534 11704864 12667443 16179260 16227588 17106237 17446862 17891140 18097445 18612260 19265852 22039431 22093031 22166994 22421439 22836101 22885520 23030059 23064052 23301705 23377657 23430059 23725295 23850759 24070470 27754749 28645028 8929532 9765397
UVRAG BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 27203177 17106237 24956373 21311563 19050071 18843052 18641390 21597469 26496610 23954414 22081109 20562859 24034250 32296183 19270696 16799551 19172397 25490155 24056303
PCNA LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
LIG1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12171929 9649448 28073635 10559261
PCNA DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17991895 18384127 31235252 28073635 12354094 9302295
PCNA CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16407242 19231300 16362051 24423875 16482215 16407252 16861906
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
TLE2 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC3 TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
CUL1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
TBL1X TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TBL1X TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TBL1X CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11389839 25241761 20181957 33054136 18193033
MAP3K1 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
MAP4K1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8824585 23331499 9003777
MAP3K1 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 10713157 19392652 18855897 9379049 26696630 17462996 12947395 18641653 23331499 23850759 12048245 11668179 21133840 21614932 21232017 12738796 9582321 24378531 22903704 11242034 10465784 15592525 17110930 26192618 9312068 17496911 11274345 15170913
MAP3K1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7839144 17143273 11971971 9639556
AHR FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14973392 10478842
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
PRKACG CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22094462 21506126 21303971 27892464
CTNNB1 TLE2 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 9118222 10080941 10831834 11713476 8756721 9751710 11136974 8757136 9488439
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
MTA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15226262 11146623 12527756 24413532
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
MTA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11146623 18451880 12167865 16807247
NR2C2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11844790 10611280
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SUZ12 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247