COPS2
|
GFER
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217148
15304329
|
USHBP1
|
COPS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
COPS6
|
BTBD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GFER
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217148
15304329
|
DDB1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19651607
0902132106
|
TP53
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11971958
|
RBX1
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17588513
19481520
|
TP53
|
STK11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17108107
21317932
|
TP53
|
STK11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23995788
21317932
|
BMX
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217965
16186805
|
TP53
|
BTBD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
ZDHHC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
28775165
|
TP53
|
IRF5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
NEDD8
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
intact
|
0806155105
18723677
|
SKP2
|
SKP1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
CUL3
|
BTBD2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
34591642
|
COPS2
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
COPS7A
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
CRBN
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
CUL4A
|
RFWD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
COPS8
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
COPS4
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
COPS7B
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
BTBD2
|
COPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
COPS5
|
ERCC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
COPS2
|
DCAF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CUL4B
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CUL4A
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
COPS3
|
DCAF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
COPS5
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
SKP2
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
21119685
|
CUL3
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22709582
|
CUL1
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22474075
|
CUL4A
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22474075
|
SKP2
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
6540196
18239684
|
SKP2
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BTBD1
|
COPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
COPS7B
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
DCUN1D1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
COPS8
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
DDB1
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16503656
18274552
16964240
21145461
18247557
|
FEM1B
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
15601820
33504946
|
RFWD2
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19295130
14739464
32041890
|
VPRBP
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
17609381
21145461
33355139
|
COPS5
|
VPRBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
COPS2
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
CUL3
|
KLHL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
CRBN
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24292625
30042095
23983124
27029275
26990986
33961781
20223979
|
CUL3
|
BTBD1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
34591642
|
BTBD1
|
BTBD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
12878161
33961781
|
CUL1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
COPS6
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
COPS2
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
COPS5
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
COPS6
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
COPS7B
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
COPS8
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
COPS4
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
GPS1
|
COPS8
|
â—¼ COLOCALIZATION
|
✅
|
|
0.85
|
0.85
|
mint
|
24421388
|
CUL4B
|
RFWD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31973889
19295130
17041588
|
VPRBP
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17079684
17630831
20870715
18606781
30590706
31973889
17609381
25532805
21145461
19295130
30166453
33355139
16949367
|
COPS3
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
COPS4
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
CUL4A
|
DCAF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
COPS3
|
DCAF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
GPS1
|
COPS6
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
24421388
|
NEDD8
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16503656
18274552
31973889
24654937
16620772
23201271
10597293
21145461
|
CUL3
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
26344197
|
COPS3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
COPS4
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
FEM1B
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
18187417
21145461
33961781
|
CUL2
|
FEM1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32941802
18187417
15601820
33961781
21145461
|
CUL4A
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17079684
21145461
32235678
|
CUL3
|
BTBD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
19995937
17543862
21145461
19295130
|
COPS4
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
COPS6
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
COPS7A
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
COPS8
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
RFWD2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CUL4A
|
DCAF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
COPS2
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CTNNB1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
COPS5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
COPS8
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BTBD2
|
COPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BTBD2
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CUL4B
|
DCAF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
DDB2
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
COPS3
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
COPS3
|
LRR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CUL4B
|
DCAF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
COPS6
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
COPS3
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
COPS6
|
COPS3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
24421388
|
CRBN
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
24292625
31973889
33961781
21145461
27142104
27294876
|
ERCC8
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16949367
31973889
29531219
26496610
33961781
21145461
22902626
|
VPRBP
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22038470
31973889
28416635
26496610
21145461
33355139
16949367
|
DCAF4
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
28446751
31973889
26496610
33961781
21145461
30945288
16949367
32140073
|
CUL4B
|
DTL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21628527
17041588
31973889
24962565
23555860
16861906
26496610
33961781
31155351
21145461
16949367
|
DTL
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21628527
17041588
23478441
31973889
23555860
16861906
29424068
30623174
31155351
33961781
30649446
21145461
16949367
|
ERCC8
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16949367
31973889
29531219
12732143
29225035
21145461
16751180
26826127
22902626
|
CUL4A
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16503656
19617556
22474075
18274552
31973889
24654937
16620772
12481031
19295130
23201271
16964240
10597293
21145461
18247557
|
CUL4A
|
DCAF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
31973889
33961781
16964240
21145461
30945288
16949367
32140073
|
COPS7B
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
CUL4A
|
ERCC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
CRBN
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
COPS2
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
COPS4
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
COPS7A
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
COPS5
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
COPS3
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
COPS3
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
COPS3
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
DCAF11
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
COPS6
|
DCAF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
COPS8
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
DDB1
|
RFWD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
COPS4
|
CRBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
CUL4B
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
CUL4A
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17041588
31973889
23555860
18593899
33961781
16964240
21145461
30945288
32140073
|
RFWD2
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17079684
25117710
33911083
17041588
32041890
31155351
19295130
14739464
16949367
|
ERCC8
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16949367
22232169
28416769
29531219
17392787
12732143
31970402
16751180
26826127
22902626
|
DDB1
|
DCAF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
19966799
33961781
16964240
30945288
16949367
|
DDB1
|
DTL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21628527
17041588
23478441
16861906
29424068
30623174
33961781
31155351
30649446
16964240
33536335
16949367
|
DDB1
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22118460
20870715
16473935
15448697
16678110
30349055
33504946
16751180
|
DDB2
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16260596
28416769
16473935
25628365
26496610
12732143
33961781
30349055
20368362
16751180
|
RBX1
|
SKP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29499133
18826954
34237211
18667692
19112177
19398581
18239684
33961781
30349055
33504946
11245432
23770852
|
RBX1
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16503656
18247557
12481031
|
CUL4A
|
CRBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24292623
24292625
31973889
32235678
23983124
26231201
25860244
26990986
27029275
33961781
16964240
32132601
21145461
27142104
20223979
27294876
|
CUL3
|
BTBD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
19995937
25011449
17543862
33961781
21145461
19295130
|
COPS8
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
COPS3
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
COPS4
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
COPS5
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
COPS5
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
COPS6
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
COPS6
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
GPS1
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
NEDD8
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CUL4A
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
COPS2
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
RBX1
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33969670
24292684
12481031
25189618
12609982
26496610
30349055
27113764
29499938
19250909
22038470
34026424
28446751
31973889
23238014
33961781
33504946
30945288
32140073
|
CUL4B
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19651607
33969670
33357448
28225217
24292684
25189618
21145461
18593899
26496610
16678110
16964240
33536335
27113764
29499938
30898011
28886238
29738775
17392787
29846670
22939629
22038470
34026424
16949367
31911655
28446751
17041588
23238014
31973889
16861906
33961781
30945288
26344197
32140073
|
CUL4B
|
DDB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
17041588
31973889
18593899
26496610
30923324
33961781
26186194
21145461
30945288
16949367
|
NEDD8
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28522566
24076655
28514442
31253590
18805092
18274552
22405651
21119685
24654937
33961781
20847044
23201271
10597293
21145461
18247557
|
CUL4A
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22952844
17079684
22118460
15448697
26613412
22910413
25349427
21145461
22474075
27462452
16473935
15811626
18606781
26231201
18593899
16678110
16964240
33536335
19295130
25982117
33759138
16260596
27113764
21113133
30898011
28886238
26976604
27203177
17392787
25795299
22939629
26344197
14739464
27294876
10585395
27573245
31911655
17041588
20870715
27203182
31973889
32235678
16861906
19966799
22342275
34251884
17626091
19287380
30945288
16949367
32140073
|
DDB1
|
CRBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23983124
29370161
28425720
24292625
26909574
26231201
25108355
25860244
16964240
27142104
24292623
26990986
30190590
27294876
26131937
32235678
29892083
27338790
32132601
20223979
|
DDB1
|
DDB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
22118460
28035050
12050362
24249678
26410533
22822215
28416769
29262658
16473935
18593899
30923324
16678110
16964240
20368362
12812979
19295130
16751180
19109893
17360488
16260596
27203177
17392787
10777491
12151405
32985517
14751237
22039351
17041588
12732143
11564863
9418871
19966799
33961781
26186194
34251884
16949367
|
DDB1
|
VPRBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21957298
25499532
26613412
30166453
17314515
18606781
28416635
24558487
19295130
30590706
24412650
17609381
27571178
25532805
16949367
28202763
27354282
20870715
25557551
19287380
33355139
26344197
|
TP53
|
DDB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16357511
19382146
|
CUL4A
|
DDB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
28514442
22118460
28035050
11564859
21145461
29262658
16473935
15811626
18593899
26496610
30923324
16964240
20368362
19295130
16751180
33759138
16260596
27203177
17609381
32985517
10585395
17041588
31973889
12732143
33961781
26186194
17626091
30945288
16949367
|
RBX1
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19327355
17183367
12149480
15448697
10230407
12481031
29547696
32296183
11861641
15601820
30349055
22405651
25540389
10579999
19250909
21822215
21778237
29958295
22863883
33961781
33504946
28591624
17132228
|
RBX1
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
16189514
15448697
10230407
12481031
17452440
22474075
11861641
18593899
30349055
19295130
22405651
33759138
30352932
27113764
26976604
27203177
26990986
19250909
27203182
31973889
32235678
29958295
22863883
33961781
33504946
19287380
30945288
32140073
|
TP53
|
IRF5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11973653
20507321
|
RFWD2
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
25117710
17041588
32041890
21145461
19295130
14739464
24298020
|
CUL2
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
CUL3
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
CUL1
|
SKP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
17704768
12840033
18667692
15456869
18239684
12504026
9636170
12609982
17439941
21145461
10559858
9736735
17438373
23951410
19398581
28614300
22464731
22013077
29137415
30349055
19270694
16774918
18173839
23770852
24085301
21249194
29499133
23868976
22310285
11961546
9430629
32313199
10559916
25143387
20160477
10230406
9663463
22524983
34237211
21119685
33422522
27542266
29103612
16880511
|
COPS2
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
CUL5
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
CUL2
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
CUL4A
|
VPRBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
COPS8
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
COPS6
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
COPS2
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
NEDD8
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
CRBN
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
NEDD8
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
DDB1
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
COPS6
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
CUL4A
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
COPS5
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
COPS5
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
NEDD8
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
16503656
21145461
18247557
27705803
|
COPS2
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
CUL4A
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
GPS1
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
7228517
19444310
|
GPS1
|
COPS5
|
â—¼ COLOCALIZATION
|
✅
|
|
0.93
|
0.93
|
mint
|
24421388
|
CUL4B
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CUL4A
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
COPS4
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
COPS6
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
COPS5
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
COPS5
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
CUL3
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
GPS1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
CUL3
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
19818716
15448697
12481031
11861641
30349055
25270598
20027226
22405651
26100637
19256485
11311237
19250909
25278611
26286618
20865015
15601839
19617556
29958295
33504946
12684064
24145166
|
SKP1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
7304783
18818696
|
SKP2
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
6540196
18239684
|
DCAF4
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
NEDD8
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16503656
23401859
19617556
18826954
18274552
21145461
10318914
24654937
16620772
23201271
31444342
18173839
10597293
10585493
18247557
17132228
|
NEDD8
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
6541102
18274552
|
CUL3
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16503656
19617556
18826954
23936405
18274552
17192413
24654937
17543862
16620772
23201271
33961781
10597293
21145461
18247557
10500095
|
COPS3
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
COPS6
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CUL1
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
GPS1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
CUL5
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31253590
18805092
10230407
11861641
14564014
25912140
19250909
30349055
15574593
22405651
|
DDB1
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
RBX1
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
12504025
12840033
12481031
26540345
11245432
29507117
10531037
16357137
30349055
15452136
12813041
23770852
29499133
12628165
11961546
29863914
33692209
27705803
33504946
12684064
|
NEDD8
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16503656
18723677
16620772
23201271
21145461
22474075
18247557
24076655
10772955
17438373
19245792
24654937
21102408
10713156
11027288
21765416
10597293
22405651
12565873
18805092
18826954
18274552
19713960
16177058
22959436
24949976
32726803
19617556
17206147
10318914
17318178
21119685
18264111
18627766
23267066
|
SKP2
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
18667692
15456869
30254149
18239684
20041211
16275325
12609982
10559858
23911321
26087183
18818696
23261596
31467278
9827542
10918611
19398581
28614300
22464731
29137415
16376880
15452136
19270694
26474281
12813041
34080260
23770852
24085301
29499133
30728155
17463251
23868976
22310285
11961546
9430629
11099048
22632967
10559916
20160477
15469821
22524983
10531035
34237211
29997244
27705803
33422522
33961781
32350066
16880511
27220724
15070733
15342634
|
CUL3
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
DCUN1D1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
CUL2
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
COPS2
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
CUL5
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
DDB1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
COPS7B
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CUL4B
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CUL5
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CUL2
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
DDB1
|
ERCC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
COPS6
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CUL5
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
COPS7A
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
CRBN
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
COPS2
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
COPS6
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
DDB1
|
VPRBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CUL4A
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
RBX1
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16189514
12504025
20832730
15448697
10230407
19933270
12840033
12904573
18723677
12504026
12481031
17452440
12609982
26540345
27697867
22474075
11245432
22767593
28152074
22822056
19245792
12706828
11861641
20399188
10748083
11956208
11483504
27910872
16759355
30349055
10713156
11027288
21765416
20638939
22405651
23770852
19942853
10648623
12565873
18826954
18805092
32145688
21169563
27591266
22660580
11961546
32313199
15361859
19250909
29863914
24949976
10230406
32726803
30653357
32015321
33692209
16123592
34237211
29958295
29103612
33961781
33504946
12684064
26725323
26344197
|
CUL3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
COPS5
|
COPS7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CUL2
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
COPS7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
COPS7B
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
COPS7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
COPS4
|
COPS7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
COPS4
|
COPS7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
COPS5
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
COPS6
|
COPS7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
COPS7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
COPS7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
COPS4
|
COPS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
COPS7A
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
COPS8
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL4B
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL1
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
COPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
COPS4
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
COPS5
|
COPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
COPS6
|
COPS7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
COPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
COPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS2
|
COPS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS3
|
COPS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS4
|
COPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS5
|
GPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS5
|
COPS7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
COPS4
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
DDB1
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
CUL4A
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
RBX1
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
CUL4B
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
RBX1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
ERCC8
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
RBX1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19270156
19440234
19557001
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
CUL4A
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ERCC8
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
DDB1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
RBX1
|
DDB1
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19270156
19440234
19557001
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
DDB1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
DDB2
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
DDB2
|
DDB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
54.0
|
1.0
|
Omnipath
|
9418871
17145710
16751180
27203177
22118460
17041588
20368362
18593899
16964240
12050362
19295130
22039351
11564863
16473935
16678110
17392787
24249678
19109893
12151405
26186194
12812979
16949367
18936169
22822215
14751237
10777491
26410533
16260596
19966799
17360488
12732143
|
RBX1
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
RBX1
|
DDB2
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
TP53
|
DDB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12771027
22336944
15856024
12509284
12170778
16357511
12967652
15927209
11971958
|
DTL
|
CUL4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21145461
19231300
16949367
|
RBX1
|
ERCC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
ERCC8
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
CUL1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RBX1
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
RBX1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
RBX1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
CUL2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL1
|
â—¼ SHARES_COMPLEX
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
SKP1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
NEDD8
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
SKP2
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
RBX1
|
TCEB2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
RBX1
|
NEDD8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
154.0
|
1.0
|
Omnipath
|
17053147
12684064
20638939
11967263
19797085
19258535
26540345
18826954
15071497
15448697
21765416
25730849
10230406
23343194
21169563
22270359
19250909
23732914
11359933
12051714
20006983
15361859
10748083
19352404
22682247
18787170
12504025
18636226
16469695
15459660
20211143
10535940
15001769
26725323
19411070
11861641
26159692
16697054
1570337
19751508
22822056
11348595
7542250
7641885
19849719
16759355
12820959
17452440
19622404
15703371
10648623
19245792
23331499
9694792
19150432
23180781
19597341
16189514
22474075
18988627
22767593
17143292
24949976
10713156
23770852
22405651
19942853
18196958
20399188
16713974
26192618
11027288
17884153
19933270
22730322
21411632
11961546
17936032
19809470
15147722
19270156
19576224
11483504
20976471
12504026
24023259
12840033
15340381
12904573
20558317
11900249
14536078
19686080
12565873
18805092
15489953
19557001
26885856
17652783
12481031
20843316
11955436
21071413
16039586
11956208
20705860
8666229
17928543
10023660
19836308
16940750
12706828
19143635
15688063
10671552
16123592
19366350
19847258
12417738
11245432
20832730
12648680
12609982
19619488
10230407
18931676
|
STK11
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20815019
11430832
17108107
16713569
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
NEDD8
|
CUL4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9694792
18805092
21145461
19250909
19231300
|
TCEB2
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
TCEB2
|
CUL2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
NEDD8
|
CUL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16620772
15688063
11696557
21145461
|
NEDD8
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
25314029
18206966
21940857
23201271
26906416
19250909
25531226
27030794
|
CUL1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
CUL1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15668399
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
CUL1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
14685242
16189514
17290223
20832730
12504025
12904573
10230407
19933270
23324393
12504026
9636170
26540345
12609982
27697867
26753747
21145461
22474075
28007894
18818696
9736735
9990852
22767593
28152074
10023660
29070679
9827542
23951410
16357137
16759355
10713156
15452136
19270694
11027288
26474281
23770852
10648623
29499133
21249194
34499862
12628165
15966899
21169563
22660580
11961546
9430629
32313199
29863914
10230406
30653357
19945379
9663463
21778237
34237211
18094045
26976582
27705803
32249768
29103612
33961781
12684064
26725323
|
CUL1
|
SKP2
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
CUL1
|
NEDD8
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
SKP1
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15668399
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
CUL1
|
NEDD8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
SKP1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
9663463
19945379
12684064
19270694
16759355
23951410
10648623
11961546
26540345
26976582
26474281
17290223
9736735
21169563
14685242
16357137
21145461
29070679
15452136
15966899
12628165
21778237
22474075
16189514
22767593
11359933
9430629
10713156
10023660
10228155
12504026
18818696
9827542
12504025
18094045
10066435
23324393
23770852
9990852
12417738
27705803
9636170
21249194
12904573
34499862
11027288
26725323
20832730
19933270
12609982
10230407
|
CUL1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10228155
10713156
10023660
|
SKP1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
SKP1
|
SKP2
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|