Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HMGA1 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 TSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LSM4 SF3B6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SF3B6 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PLEC CS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ELP1 BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HMGA1 YKT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LONP1 ACO2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A1 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
BAG6 ATXN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
BLVRA MAP2K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0800750105 18463290
BLVRA MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0800750105 18463290
LONP1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDKN2A MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
EZH2 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
CGN TJP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SRP14 CLASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK1 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
RPS15A DDX39B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
DNMT1 MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16473673
DTX2 TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EIF2B3 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16288713 15054402
PLEC ITPR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
PARP1 MAPK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
NUFIP2 PEX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RAE1 NUMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17172455 0609582104
PLEC PEX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TJP1 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219015 16944923
SMC1A RAE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18832153 0807660105
RPS15A SRP14 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SSR4 SSR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 28218252 11964406
RPL30 RPL35 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NUP188 PRPF8 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AP2A1 AP2S1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CDC42 RAB1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
MYO6 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467281 26950368
AP2S1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REPS1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CAP1 MCM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 25963833
CDC42 MYO6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 31871319
CDC42 RAB1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
RNF43 MYADM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC1 STOM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 31871319
RPL30 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL34 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL35 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL30 RPL34 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
SSR3 SSR4 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CLTC MYO6 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
SMC1A MCM6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27173435 16438930
RCC2 RAC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25074804 12919680
DDX46 SNRPA1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
SF3B6 SNRPA1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SRPK1 CHTOP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
EZH2 DDB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27634302 23238014
SART1 SF3B6 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DDX46 SF3B6 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
RABGGTB YKT6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2B3 EIF2S2 â—¼   GTPASE_REACTION ✅ + 0.84 0.84 Signor 15054402
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
LSM4 SNRNP40 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
AP2A1 NUMB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATP6V1A ATP6V1B2 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ALPP GEMIN4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
RAC1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11021801 16189514
HCFC1 PPP1CB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CHTOP DDX39B â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
RAB1B RAB1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 26344197
RPL34 RPL35 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EIF2S2 RPS15A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS15A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTPBP4 RPL34 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RAB1A RAB1B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PFKL PFKM â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PRPF8 SF3B6 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAB1B RAE1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 9437002 26186194 33961781
RAP1B CDC42 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 26344197
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
DNMT1 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27728808 23708667 34079125
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SEC22B SEC23A â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
S1PR1 GNAI1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 8626678
SRPK1 U2AF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22365833 9472028 28514442 23602568
SART1 SNRNP40 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
FLOT1 FLOT2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NUMB AP2A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17203073 23211419 12942088
ARF4 GBF1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17956946 22389062 23567335
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
CDC37 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC37 PSME1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC37 RPS15A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
NRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
PSME3 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18805416 31565481
LYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11782428
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
NOD2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14560001 15692051 15692050
RAE1 RAB1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 8294464
SLC16A3 SLC16A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921872 11719518 16260747
RPS15A TSR1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
GTPBP4 RPL35 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
EIF2S3 RPS15A â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
FLOT1 FLOT2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EIF2S2 EIF3I â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EIF2S3 EIF3I â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
GTPBP4 RPL30 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ACO2 FH â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RBM25 SART1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PSMB2 PSME1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
HADHA HADHB â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CS IDH3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
LSM4 PRPF8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBM25 SNRPA1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
NCBP1 SART1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
NCBP1 RBM25 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
LSM4 SNRPA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PPP1CB PPP1R12A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
SNRNP40 SNRPA1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
NASP RBBP4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PSMB2 PSME3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
MCM2 MCM6 â—¼   CORRELATES + 0.96 0.96 CCLE 31978347
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RANBP2 RANGAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EEF2 RPS15A â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATP6V1A ATP6V1B2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
LSM4 SART1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EEF2 RPL34 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL35 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL30 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HADHA HADHB â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PRPF8 SNRPA1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL30 RPL34 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL34 RPS15A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PRPF8 SART1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL34 RPL35 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL35 RPS15A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SART1 SNRPA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL30 RPL35 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PRPF8 SNRNP40 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
GBF1 RAB1B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22013193 16926190 15813748 17956946 12047556 17429068 18524849 16030262 16633337
ARF4 RAB1B â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22013193 20357002 17429068 18524849 16030262 16633337
SEC22B RAB1A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21532587 24917561 20966969 17287728
YKT6 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
ARF4 GBF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22013193 20357002 17429068 18524849 16030262 16633337
HRAS CDKN2A â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 7510700 7673236 8551221 9069260 9763606 9846483
EZH2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19954516 21572997 23289480 23826727
STAT3 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15870198 16861352 25854163
EIF2S2 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
S1PR1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 8626678 31160049
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
ITGB1 LYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
PRKACA ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 2847175 1847804 8132598 19144319 12529267 14741364
KRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP2K1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9305919 7719937 7568001 10602027 12681450 7719938 7544001 7528668
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAP2K1 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19541618 8381049 19565474 18775330 15547943 19114553 17178906
NRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK1 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12721286 15212693 14517250 14662762
MAPK1 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17081983 15547943 19114553 17570479 18280113 21185392 19541618 8381049 19565474 7766652 10978317 18632668 9468497 17178906 8636128 11737068 32559461 18775330 12576304 12885780 15212693
MAPK1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23597856 26637332 16627622
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MCM6 MCM2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 20211142 22939629 12207017 26496610 30100344 22540012 22863883 25963833 17296731 14681455 26344197 12614612 12694531 25416956 16189514 27173435 26167883 16899510 10567526
MCM2 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
PRKACA RAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8463283 19651783 27760305 12089143 1551424 90343822
PRKACA THOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969067
RAB1A SEC23A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21532587 24917561 20966969 17287728
RAC1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 26430964 16189514 11021801
RANBP2 RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16204249 9019411 11854305 19526197 22464730 12192048 22194619 11709548 21518904
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368