Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ERBB2 CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730868 9461599
ARF3 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SHANK3 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 PFKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 COPS6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
KRTAP4-12 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PFKL ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PRPF8 BCAS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BCAS2 SF3A1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
BCAS2 RNF113A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
COPS6 PFKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DDB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EEF1G HNRNPH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCB1 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 HNRNPL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FGFR3 SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 TSNAX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIF1A FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16601206 15192019
HIF1A GPI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10823814 16126909
HIF1A PFKL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8089148
HIF1A ROS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23626778 17942638
HNRNPH3 HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPU RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKE PFKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KRTAP4-12 PFKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LRRK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
PFKL MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MATR3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB MAP3K8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFKL MAP3K8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNFRSF1A PFKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFKL TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFKL PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PFKL RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFKL TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SF3A1 PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNRNP70 PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRPF40A UBR4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TUBB RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SFPQ RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RNF113A SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SF3A1 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TUBB TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CSTF1 SNRPF â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MAPK14 MAPKAPK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 14499342
ABCF2 EFTUD2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RNF113A SF3A1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CDC5L MSH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DDX23 SF3A1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
SNRNP40 SNRPF â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
POLR2G SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CSTF1 SF3A1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
POLR2D POLR2G â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
POLR2G SF3A1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DUSP16 MAPK14 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
EFTUD2 SNRNP200 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BCAS2 SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EEF1A1 EEF1G â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
SFPQ SNRNP70 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CDC5L DDX23 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
COPA SF3A1 â—¼   CORRELATES - -0.82 0.81 CCLE 31978347
AKT1 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19262695 26344197
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 AP3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 27424887
CFTR COPB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
MATR3 COPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29884807 26496610
VCAM1 COPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
EEF1A1 VARS â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
ESR1 SNW1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 19934264
LRRK2 MSH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
VCAM1 SFPQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SOX2 UBR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30894683 23667531
VCAM1 UBR4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SF3A1 SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MAPK14 MAPKAPK2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
BCAS2 HNRNPH3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPL SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TNFRSF1A TRAF2 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 10795740
FLT1 FLT4 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HNRNPH3 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BCAS2 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SNRNP40 SNRNP70 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABCF2 SNW1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
EFTUD2 SNRNP70 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PRPF8 UBR5 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SNW1 UBR5 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AKT1 MSH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24412244 28205554 28628118
SNW1 MSH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12840015 20467437
SNW1 SFPQ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12840015 20467437
TRAF2 TAB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19150425 17384642 14633987 10882101
COPS6 DDB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
SF3A1 SNRPF â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPU RAB28 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
AKT1 ARNT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28205554 28628118 15833858
CFTR COPG1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR FAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR UBR4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
TAB2 TRAF2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HNRNPL SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BCAS2 SNRNP40 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SNRNP40 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RNPC3 SNRPF â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BCAS2 SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
LRRK2 DDB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
SNRNP200 SNRNP70 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
SFPQ SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MSH2 SNW1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
DDX23 SNW1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
DYNC1H1 TUBA1A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CDC5L BCAS2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 20467437 7945687
CDC5L GCN1L1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDC5L DYNC1H1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PRPF8 RNF113A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RNF113A SNRPF â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RNF113A SNW1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SF3A1 SNW1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SF3A1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EFTUD2 RNF113A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PFKL PFKM â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PFKM PFKP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
COPG1 COPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 14729954 26344197 22939629 28514442 9751720
SNW1 DDX23 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34079125 12840015 20467437
SF3A1 SNRNP40 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
PRPF40A SNRNP70 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
SNW1 CDC5L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 29395067 12840015 20467437
CDC5L SFPQ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11101529 22939629 26344197 20467437
EEF1G VARS â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
FN1 CSK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
AKT1 EEF1G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AKT1 SMARCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568092
TNFAIP3 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18353649 15661910
MAPK3 MAP3K3 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAPKAPK2 TRAF2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
BCAS2 SNRPF â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
DPF3 SMARCB1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PRPF8 SNRNP70 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
SNRNP40 SNW1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
DDX23 SNRNP70 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TNFRSF1A TRAF2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
PRPF8 SNRNP200 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
COPB2 COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
COPA COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
DDX23 EEF1G â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
BCAS2 SNRNP40 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
KRTAP4-12 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
ABCF2 EEF1G â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EEF1G UBR5 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EEF1G SNRNP200 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PFKP RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RAB28 TUBB â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
EEF1G EFTUD2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
EFTUD2 SF3A1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SNRNP40 SNRPF â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
DDX23 SNRPF â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
BCAS2 SNW1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EEF1G SNW1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CDC5L RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
COPA COPG1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
COPB2 COPG1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PRPF8 SF3A1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HIF1A ARNT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12391259 10085255 16954218 7836384 17916562 26496610 8663540 34592152 14764593 20603618 14668441 21512126 11606485 26350169 9079689 24056783 19845609 27684187 11782478 19168635 23363003 26160453 28628118 15850782 17197389 21620138 15833858 23086815 24434214 20458141 18024476 23458834 12810720 28514442 15347669 9704006 27320910 20562859 11829741 15031145 21435239 20049704 15479785 20932347 12393189 11025203 16861921 9159130 10671489 16520375 15615775 17213817 28205554 23796364 15319539 11593383 19251694 20699359
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DDX23 SNRNP200 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SNRPF SNW1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DDX23 SNRNP40 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RNF113A SNRNP200 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BCAS2 SNRNP200 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DDX23 EFTUD2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TNFAIP3 TNFRSF1A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SNRNP70 SNRPF â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CDC5L SNRPF â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
SF3A1 SNRPF â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
SF3A1 SNRNP200 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CDC5L SNRNP40 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SNRNP200 SNRPF â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
MAPK14 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
BCAS2 EFTUD2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDC5L SF3A1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EFTUD2 SNRPF â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRPF8 SNRPF â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
BCAS2 PRPF8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC5L EFTUD2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC5L SNW1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PRPF8 SNW1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SNRNP200 SNW1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC5L PRPF8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC5L SNRNP200 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DDX23 PRPF8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EFTUD2 SNW1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BCAS2 CDC5L â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SNRNP200 SNRNP40 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EFTUD2 SNRNP40 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EFTUD2 PRPF8 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EFTUD2 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF8 SNRNP40 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF8 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19376078 16340011 16083285 26506913 27784766 24467442
AKT1 COPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26318036 23095642
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 MAP3K8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 12138205 23109003
ARNT FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 1823643 12829734 9159130 13130303 9746763 12080085 11566883 10403805 8943284 15451019 11528470 9278421 16887934 9295307
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
PRKAA1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19419994 20861072 20952391 24727471 26079370 19095655 10862786
DUSP16 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12794087 20936779 26186194 11489891 14586399 11359773
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ESR1 RELB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17369819 20034404 19433448
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
FGFR3 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
HIF1A FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 1823643 12829734 9159130 13130303 9746763 12080085 11566883 10403805 8943284 15451019 11528470 9278421 16887934 9295307
MYD88 FLT3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
PRKAA1 GFPT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19170765 17941647
HIF1A GPI â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
TNFRSF1A MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TNFRSF1A MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP3K3 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
TRAF2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAPK14 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 21675959 16456544 23602568 17395714 21988832 10581204 23331499 21071413 27898710 23047924 10922375 12738796 11551945 26496610 25852190 18988627 15629715 18669648 15187187 11042204 26186194 25241761 8846784 17906627 14499342 9922370 7923353 9768359 18039929 25255283 7592979 17255097 11274345 23455922
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK3 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21675959 17242355 7592979 14499342 14967450 23583303
TRAF2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNFAIP3 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20448643 25416956 24008839 8692885 31515488 32296183 10544141 16713569 10755617
TRAF2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 26212014 8565075 8943045 8612133 16713569 16611992 22179575 11821416 7544915 12721308 21741934 10795740 21119000 19150425 27321185 25241761 15115707 18776134 15743837 15485837 20448643 12887920 24735611 20333651 18022363 19815541
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368