Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PTPN11 VAV3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 12577067
FOXO3 CAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11884717
EPPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18208837 7534297
CANX IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CEBPG HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21289291 12183449
COPA IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESYT1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FOXO3 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18268343 0706790105
ROS1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 27532863 29650039
HIF1A PFKL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8089148
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A ROS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23626778 17942638
HYOU1 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKDC IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMC2 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ROS1 LACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NFE2L2 ROS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22051043 17540521
SP1 PEBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24386147 9105667
ROS1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6788191 17416557
SP1 RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742449
SP1 ROS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22113199 17890327
ARCN1 COPB1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
COPB1 COPZ1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
EMD VAPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25910212 34079125
ARCN1 COPZ1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SMC2 SMC3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
VAPB SNX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VAPB TACC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VAPA TACC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
ABCE1 EIF2S1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIF1A APEX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10594042 16189514
VAPA CKAP4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
ABCE1 EIF2S2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NUP205 NUP93 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ROS1 PTN6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17416557 11266449
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DNAJB11 SNX5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNX5 CDC37 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP1 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12538496 11479230
NFE2L2 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22493435
FOXO3 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18195003 18772130 19324885
HIF1A RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15270719 14742449
HIF1A SLC2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15059920 7493931 9525945
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
HSPA5 HYOU1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
COPE COPZ1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
CDK5RAP3 DDRGK1 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
ARCN1 COPZ1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPB1 COPZ1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPA COPZ1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
COPB2 COPZ1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
COPB1 COPE â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ARCN1 COPE â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
COPB2 COPE â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
COPE COPA â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 31712447 9482852 8858162 10921873 26344197 22939629 27684187 16169070 9751720
ARCN1 COPB2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ARCN1 COPA â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NUP205 NUP93 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ARCN1 COPB1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPA COPE â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
HIF1A FOXO3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A SLC2A1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A SLC2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19828020 17426252 18097583 15525582 17431122 16025159 17486380 15620252 23661628 18268343 11120745 17322369
PTPN1 ROS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17416557
PTPN11 PTPN6 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 PTPN6 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN6 ROS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 11266449 17416557
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368