Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
LYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
ZAP70 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211965 10556826
KIT GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16873377 18697750
ERBB2 BLNK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
BLNK KSYK â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 21482705 10981967 18369315 21822214
LYN JAK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 9573010
IL4RA TYK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGFR2 PTN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12887919 28065597
PGFRB ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 7531698 30898150
NTRK1 PTN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29715200 15557341
PTN6 RL10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
FCG2B PTN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 8577729 9603468 9148918 7716523
PTN6 RL23A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL32 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN6 RL37A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27432908 31980649
PTN6 CH033 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27432908 31980649
PTN6 RL18A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27432908 31980649
VAV PGFRB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22974441 10938113
LIRB4 LIRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL23A RL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26344197
RL32 RL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26344197
RL23A RL4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26344197
RL23A RL32 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26344197
RL18A CH033 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GRB2 ZAP70 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23267066 7629168
BLNK CD72 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10820378 16189514
INSR JAK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12456798 8912646
TYK2 VAV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10673353 16189514
BCR KIT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8757502 25241761
PTN6 GAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11812650 11895767
PTN6 CXCR4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 10506573
BLNK VAV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 9697839
VAV EPOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9162069 16713569
NSUN7 PTN6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PTN6 RL35A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28675297 27432908 31980649
PTN6 PTN12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27432908 33961781 31980649
RL13 RL5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
RL5 RL7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
RL13 RL23A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 33961781 22939629 26344197
RL23A RL7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 33961781 22939629 26344197
RL13 RL4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
RL4 RL7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
RL13 RL7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 33961781 22939629 26344197
RL13 RL21 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 22939629 26344197
RL21 RL7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 22939629 26344197
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
PGFRB EGFR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9506992 7531698 16713569
LCP2 KSYK â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15388330 16189514 22267732
ERBB2 PTN6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22973453 28065597
NTRK1 PTN12 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25921289 19167335
PTN6 BCR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27432908 9788431 9211920
ABL1 PTN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10488096 8692915 7512963 10574931 8114715 12468540
KSYK GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 22267732 11964172 10747947
LYN EPOR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9573010
LCK LCP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16354835 8702662 10556826 21725281
KIT JAK2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8611693 7527392 9355737
INSR PTN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12468540 8114715 7512963 8692915
FAK2 ERBB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 10713673 16713569
PTN12 ERBB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21376233 19167335
P85A BCR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16219545 8781408 18346204
BLNK PTN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15588985 10903736 16189514 11356834
SSR2 PTN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9305905 16189514 11920268
ERBB2 GRB2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 14967450
KIT ABL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12374739 24728074
ABL1 ERBB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22973453 16273093 19275932
VGFR2 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10319320 16966330
FAK2 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 10354709 19380485 10329689 8695788
ZAP70 LCP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10660534 8702662 24584089 9047237 12190313
ZAP70 PTN6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10458769 16189514 8638162
CAV1 INSR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10598578 31217420
FAK2 VAV â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10867021 16713569
RL18A RL10 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
LIRB1 PTN6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18802077 9842885
LYN IL3RB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 7636265 9973406
VAV JAK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9162069 7530656
PTN6 FAK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10521452 10747947
RL13 RL10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 33961781 26496610
RL10 RL7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 26496610 33961781
RL37A RL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RL18A RL23A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 26344197
RL23A RL37A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RL37A RL4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RL18A RL13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197
RL13 RL37A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RL18A RL7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RL18A RL32 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RL18A RL37A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 26344197
RL32 RL37A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197
RL37A RL7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
LCP2 ZAP70 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BLNK GRB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
JAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24240702 9363897 10635327 16273093 23838182 10358079
FAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10980697 16713569 10777553 15657067
LCP2 P85A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21282515 15388330 15929943
KIT LCK â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9788619 24728074
TYK2 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 8780698 7629131
CAV1 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12176037 16189514
NTRK1 P85A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25921289 8226808 8384556
KSYK PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 34362877 10871605 10747947 10072516 11356834
CLM1 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15549731 15184070 14662855
VGFR2 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12887919 28183800 28065597 18377662 9405464 16453023
LIRB2 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18802077 9531263 9842885
ROS1 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11266449 17416557
PGFRB PTN12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12614164 21376233 19167335
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCR GRB2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
LCK ZAP70 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GRB2 KIT â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
NTRK1 ABL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10708759 10679771
VAV ABL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19234221 11790798
EGFR LCP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
GRB2 LCP2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
NTRK1 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11733534 25921289 10748052
EPOR GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 7534299 9129019 8647802
FGFR2 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24440983 22726438
LYN CD22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10748054 8647200 10228003
LCP2 PTN6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9765283 15588985 16189514 8760799
LCK P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8294442 9461588 7504174 34079125 8246987
P85A JAK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17474147 8702385 16135792 10026141
PTN6 JAK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8943354 10772872
PTN6 CD22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11356834 8627166 15588985 9890995 7618087 10228003 11551923
PTN6 P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11337495 9452499 11160222 10488096
VAV P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9162069 16713569 9891995 17050525
LIRB4 PTN6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18802077 9151699 9973385
PILRA PTN6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10660620 10903717
PTN6 IL4RA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9392697 11714803 27742835
PTN6 KI2L3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8691154 9148918 8648092 8574854
PTN6 PECA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9774457 10350061
RL21 RL23A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22863883 22939629 26344197
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ABL1 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23950177 16713569 17474147 14725908 9407116 9516488 8194526 19380743 19823681 7926767 16955467
ABL1 BCR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12543778 1712671 8112292 21653319 11780146
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
ABL1 P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 1383690 16135792 8781408 17474147 8294442 16219545 19380743
VAV EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 10938113 22973453 24658140 16273093 25402006
PTN6 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9733788 22973453 25187647 7673163 28065597
P85A EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21701776 25241761 16713569 7499252 19531499 22973453 25187647 8662998 16273093 25754235 7797556 31959764 16230374 7531698
ZAP70 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 22973453 24658140 16273093 25402006
EGFR PTN12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 28065597 25402006 21376233
EGFR ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500850 25241761 30898150 17486068 11526509 9461599 23866081 17426253 10572067 11500516 24557338 8665853 15657067 19060928 16516204 19650109 20211985 25315821 23436906 21278786 25898135 32669362 1346931 24189400 21044682 18803307 16843263 28369073 7531698 16713569 17148612 21203579 17307140 1706616 16207817 7797556 12354693 11408594
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
EGFR LYN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 22973453 24658140 23764002 25402006 16799092 34079125 23866081
PTN12 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28675297 9135065 21706016
PGFRB GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7935391 7486683 16189514 16713569 9362449 10026169
KIT GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 24728074 7523859 17452978 17904548 10377264 8950973 10022833 7523381 12444928 8647802
JAK2 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7500025 17474147 8536716 8950973
GRB2 CD22 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10748054 11551923
EPOR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8647802 16713569 7534299
PTN6 LYN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8692915 11042209 10488096 10574931 10871605 8114715 12468540 22624718
LYN KIT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9341198 11825908 24728074
LYN KSYK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7831290 9820500 8621719 11536198
LYN CD22 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9547345 9601638 9480991
LCP2 VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 10347175 9341187 21725281 8703037 19635790 11331248 9047237 8673706
PTN6 CD72 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9740800 15588985 12882840 11114375 9590210
PTN6 LCK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11294838 16189514 19167335 10488096 8692915 7512963 10574931 8114715 12468540 10617656
KSYK LCK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 8798676 8621719 15536084 7539035 8798764
LCK ZAP70 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 7961936 10556826 8798643 9685404 22242145 7539035 10318843 15144186 16461343
LCK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11572860
JAK2 IL3RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21965659 7527392 10772872 18692472 16437163 7775438
CXCR4 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17158356 10506573
P85A KIT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7509796 25241761 1382595 16713569 24728074 17452978 12878163 11071635 7537096 10022833 9233773
PTN6 KIT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12614164 9528781 7684496
ZAP70 VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9151714 16339550 7798261 8530437
PTN6 CD33 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10556798 16189514 10206955 24216507
PTN6 LAIR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10660620 16189514 9285412 15703304 10903717 11160222 10764762
KSYK VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 8900182 11331248 8986718 11262396
PGFRB P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10752619 7536927 9153411 8382612 10697503 1314164 15377662 8388538 19864249 11710529 1330535 7680644 7678051 7531698 1372092 7486683 16135792 16713569 8564419 7692233 11896612 8670861
PTN6 SHPS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10660620 16189514 14662855 10660565 8943344 9632768
PTN6 IL3RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9162089 7528537 8246974 9254654
RL18A RL4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 30021884 22939629 26344197
LCP2 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17235283 5219525
GRB2 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
GRB2 BCR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5214841 11726515
PTN6 VAV â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16189514 8632004
RL32 RL4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22939629 33961781 26344197
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
KSYK CD22 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 8647200 8627166
PTN6 PGFRB â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 19167335 9452499
P85A KSYK â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15536084 16921024
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
P85A ERBB2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12896906 9756944 22973453 16843263 16273093 21075308 1351056 7531698
ERBB2 GRB2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PTN6 GRB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10660620 16189514 8632004 11964172 25535246 10747947
JAK2 EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 14982882 12441334 11779507 8343951
GAB2 P85A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9660791 16135792 10871282 11782427 16253990 14530346 26839216 12506011 16219545 11334882 10068651
INSR P85A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11796522 8276809 8385099 1334490 10500481 8567177 14729945 9593725 7589433 15629149 7659087
P85A EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9162069 16713569 24113870 12506011 7559499 15644415
PTN6 EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7528537 7228577 7889566 7528577
RL10 RL5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 26344197 26496610 33961781
RL10 RL4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 26344197 26496610 33961781
RL10 RL23A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 26344197 26496610
RL4 RL5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 25866880 22939629 26344197 26908445
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
ERBB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9710588 11173924 21278786 16713569 9756944 24189400 31980649 22973453 24658140 30898150 16273093 17875712 16729043 11606575 8665853
BCR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 8112292 11726515 15143164 9747873 10887132 8995379 8955135 9174058 14725908 21706016 33961781 19380743 32203420 9178913 7529874
LCP2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 8695800 11314042 10204582 8995445 15929943 12176364 25416956 32296183 9565634 10224278 7706237 20936779 19380743 17235283 9716598
VAV GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 16713569 8900182 8647120 9013873 7809090 18692475 29997244 16339550 15558030 32203420 10207103
P85A GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25416956 9174058 11418612 21706016 7544353 18346204 7737969 9886492 16219545 19380743 7642581 7759531 16713569 8621719 7642542 9541596 8647120 32814053 20936779
BLNK GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 9697839 16912232 10820378 9705962 21822214 10556826 11449366
GAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25416956 31980649 21706016 10068651 16371368 10391903 32296183 15143164 10913131 19523899 19172738 11782427 19380743 11882361 9660791 16253990 33961781 20936779
EPOR JAK2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12644574 16787943 16912036 16076903 11847100
LCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16076903 16787943 17570479 11847100
NTRK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10708759 10679771
ABL1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9407116 10405761 12522270 11780146 8622703 9178913 1712671 12124177 7529874 9467953 8955135 20841568 8112292 16912036 12543778 11376433
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
LYN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 31980649 16799092 23866081 24658140 11160627 23764002 25402006 22430206
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
ZAP70 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
GRB2 LCP2 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
ERBB2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 31980649 9756944 21278786 16273093 24189400 11173924 9710588 24658140 11606575 14967450 17875712 16713569 16729043
BLNK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21822214 11449366 10820378 16912232 9697839 16189514 10556826 9705962
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
LCP2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7706237 20936779 10224278 8695800 17235283 15929943 25416956 19380743 9716598 32296183 10204582 11314042 8995445
KIT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24728074 8950973 7523381 10022833 7523859 8647802 16713569 17452978 17904548 10377264
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
LYN GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19171907 18950707 11971018
LYN CD22 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 32323266 10228003 8647200 9586639
LYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24728074 11825908 9341198 17570479
LYN EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9573010 12441334 10579919
ZAP70 LCP2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12415267 12731048 15735648 17371980 20814939 23620508 7600293 8642247
GAB2 LCP2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10849428 10982827 11572860 12640133 16212621 19909365
GAB2 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15286727 23109003 12640133 11323691
ZAP70 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 12817019 9047237 15388330 10660534 15286727 23109003 8892604 12640133 12640123 11323691 8702662 23758320
LCK LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16354835 21725281 8702662 10648627 10556826
LCK ZAP70 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 23874979 7961936 17579062 29073235 30992398 15292262 23933134 31932281 21829558 15592455 21917715 9199177 8798643 7612267 16339550 23331499 10202147 22238573 16189514 32184287 21103055 7642520 33531381 12648457 12522270 17998387 9685404 20945976 16839418 15144186 16461343 16094384 11270871 17192257 10037717 8756661 19606965 23758320 27869819 16111633 25137454 15268851 17942891 33482200 11514606 11514605 15659558 10556826 10318843
LCK CD33 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10206955 10887109
LCK KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17570479 9788619 24728074
JAK2 TYK2 â—¼   PHYSICAL_INTERACTION 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
JAK2 TYK2 â—¼   SHARES_COMPLEX 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
KIT JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8611693 7527392 15526160 9355737
JAK2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18644434 21183952
JAK2 EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10660611 12441334 7559499 8343951 18672044 11779507 12027890 11443118 12524467 9030561 9573010 15212693 10579919
ZAP70 GAB2 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10358138 10562324 10849428 10982827 11353765 11447289 11572860 12138178 12415267 12640133 12707331 12731048 15240681 15699106 15713798 15735648 16212621 17371980 19833085 19909365 20814939 21059766 23414611 23620508 23886063 7600293 8478617 8642247 9625766 9738502 9751747
ZAP70 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23980151 18644434 11334882 11572860 23109003 15170389 12640133
INSR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9756945 10598578 12036959 17699617