Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ERBB2 CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730868 9461599
GRB2 FLNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
NTRK1 PTN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15557341 29715200
PGFRB ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 7531698
TGFI1 PAXI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11463817 16713569
PTN12 RHG10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 28675297
PTN12 FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28675297 31980649
PTN12 FLNB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28675297 19293945
VAPA PPIP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LPXN PPIP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PTN6 PTN12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27432908 31980649
VAPA PTN12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 28675297 31980649
ERBB2 PTN6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22973453 28065597
PGFRB EGFR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9506992 7531698 16713569
SHC1 PGFRB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 8195171
NTRK1 PTN12 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19167335 25921289
PTN12 LPXN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 12674328
PTN12 ERBB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19167335 21376233
GRB2 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21706016 17474147 12577067
ERBB2 GRB2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 14967450
SHC1 PAXI â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 34079125
GRB2 PPIP2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19380743 21706016
ERBB2 VAPA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24189400 31980649
BCAR1 GRB2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PTN12 WASP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19167335 11711533 14707117 15588985
FLNA FLNB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTN12 CSK â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11158295 27880917 28675297
PGFRB PTN12 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19167335 12614164 21376233
PTN12 PPIP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27880917 31980649 9804817 28675297 28514442
SHC1 CSK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10037694 19380743 12048194
CSK PAXI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7529872 11695992 31980649 14665621
TGFI1 PTN12 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10092676 16713569
VAPA EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25754235 31980649 23956138 20029029
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
EGFR CSK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24797263 24658140 31980649 16729043 25402006
PTN6 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9733788 22973453 28065597 7673163 25187647
PGFRB GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7486683 7935391 9362449 16713569 10026169 16189514
PAXI PTN12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 10085298 27880917 10625692 9497381 10400685 19167335 28675297 28514442 11950600 34079125
PTN12 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9135065 21706016 28675297
EGFR PTN12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 21376233 31980649 28065597 25402006 20029029
BCAR1 PTN12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27880917 9920935 9285683 8887669 12714323 9748319
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
SHC1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30898150 10085134 9019162 24658140 22973453 16729043 9710588 28065597 16843263 9756944 16713569 16273093 8665853
GRB2 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
ERBB2 SHC1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
PTN6 PGFRB â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 19167335 9452499
BCAR1 PAXI â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 9759889 34079125 8810278 11577104
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
ERBB2 GRB2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PTN6 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8632004 10660620 25535246 10747947 16189514 11964172
WASP GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10224664 8805332 16713569 8892607 16189514 9307968
PPIP1 WASP â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9488710 16189514 19041431 14707117 16418535
PTN12 PPIP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11971877 32296183 14707117 9422760 11711533
SHC1 PTN12 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24412244 33961781 27880917 31980649 7929214 11432829 8626541 28675297 12052829 11342545 28514442 24189400 19380743
SHC1 EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10595738 24797263 24658140 7542744 21278788 9130710 28065597 10766863 10635327 8034616 24430869 7518560 12577067 19531499 31959764 8810340 9742218 11196191 23799367 23956138 9756944 16713569 11370743 8665853 18271526 15657067 11408594 20473329 22973453 16729043 20935677 20067773 7506413 16273093 25754235 8610109 24189400 26551075 9388490 8887653 31980649 7542991 9544989 9020193 25187647 25402006 30544639 10049786 8662998
FLNB FLNA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12393796 22939629 26496610 26344197
NTRK1 SHC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CSK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12767520 12048194 18829532 9819392 19380743 10037694 17673906
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
ERBB2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 31980649 9756944 21278786 16273093 24189400 11173924 9710588 24658140 11606575 14967450 17875712 16713569 16729043
ERBB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 28065597 23331499 9756944 16273093 8026468 9710588 10085134 24658140 9590694 16713569 16729043 16843263
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
NTRK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8155326 9715270 8226808 15056278 10708759 8552402 9856458 23331499 10629055 10092678 12446789 8524391 25921289 7541035 8183561