Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SHC1 LYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
JAK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9670964
LYN JAK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 9573010
JAK1 IL3RB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15194700 11557047 21965659 9516124
SHC1 LYN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7516469 7650013
IL3RB IL5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7957082 1495999
LYN IL3RB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 7636265 9973406
1433Z IL3RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10477722 8278375
IL5RA IL3RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9516124 1495999
PTN6 JAK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8943354 10772872
IL3 IL3RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18692472 9278420 7957082 8649415
PTN6 LYN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8692915 11042209 10488096 10574931 10871605 8114715 12468540 22624718
PTN11 JAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8995399 9794795 11036942 12270932 12403768
JAK2 IL3RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21965659 7527392 10772872 18692472 16437163 7775438
JAK2 IL3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 2681215 1400495 1396555
JAK2 IL5RA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 2681215 1400495 1396555
JAK2 CSF2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 2681215 1400495 1396555
JAK2 IL5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 2681215 1400495 1396555
IL3RB CSF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8278375 2645577 18692472 7957082 1702217
IL5RA IL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7721873 22153509 10823900 7957082 1495999 1732409 10880230
PTN11 IL3RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15194700 9973406 9162089 9254654
PTN6 IL3RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9162089 7528537 8246974 9254654
SHC1 JAK2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 7535773 9126968
SHC1 IL3RB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 15194700 10477722 10704825 16437163
PTN11 JAK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7559603 8995399 9442080 8639815 8912646
IL5 IL5RA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LYN JAK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8197119 16492764 16720384 7512720 10537111
LYN IL5RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11823534
LYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23109003 7650013 7516469 10329689
JAK2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9126968 7535773
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
IL5RA JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9516124
JAK2 CSF2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
JAK2 CSF2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
IL5RA JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 9516124 17312100 11823534 7602114 15795318
IL5 IL5RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 23331499 1833065 7721873 10823900 1732409 10880230 22528658 7957082 1495999 8567620 11748263 22153509