Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PPP6C SEC24A â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 21532587 23864707
CSK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
CSK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
SNCA GSK3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21985244 8209944
HMGA1 YKT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YKT6 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
YKT6 NSF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
YKT6 GOSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
ACIN1 ABCF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ACIN1 PNN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNCA AP3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BCAS2 SF3B5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
BCAS2 SF3A1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NSF BET1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
STX5 BET1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15215310 12388752
BRAF PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
HRAS CHMP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLTA MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
HNRNPL CSE1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CSE1L PPP5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FNTB KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12374986 24294527
GOSR1 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
HNRNPA3 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRAS HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
PTPN11 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
PAFAH1B1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
HSP90AA1 PAFAH1B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20133715
HSP90AB1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RHOB INSR â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
KRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
PTPN11 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
LMNB1 LMNA â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MATR3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
PTPN11 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
NSF STX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
PAFAH1B1 NUDCD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16754861 0602916103
RIPK1 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
PPP6R1 PPP6C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208117 16769727
SF3A1 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SF3B5 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SFPQ TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1B SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BCAS2 SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACIN1 HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACIN1 RBM14 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CSTF1 SNRPF â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PNN SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
STX7 YKT6 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
ACIN1 CPSF6 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CPSF6 SFPQ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAFB SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MATR3 TPR â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NUDT21 SNRPF â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
SNRNP40 SNRPF â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BCL2L2 SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
AP3B1 AP3M2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CSTF1 SF3A1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 34591642
NRAS BRAF â—¼   PROXIMITY ✅ 0.81 0.81 mint 30194290
BCL2L2 HNRNPL â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AP3D1 AP3M2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
VIPAS39 VPS33B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPL PNN â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACIN1 SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BCAS2 SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NAPA VTI1A â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
HNRNPA3 SF3A1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SFPQ SNRNP70 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA1 SF3A1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EIF2B2 EIF2B5 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACIN1 HNRNPC â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CPSF6 HNRNPC â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACIN1 SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CPSF6 SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
COPA SF3A1 â—¼   CORRELATES - -0.82 0.81 CCLE 31978347
SF3A1 SF3B14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SF3B5 SNRNP70 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
NSF SCFD1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
PNN SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LRRK2 TPR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
SFPQ TPR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 19293945
RHOB STX7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
STX7 SCFD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
STX11 STX6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BET1 STX6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 33961781
STX6 YKT6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
STX6 VPS53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20685960 34079125
YKT6 PTAR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PGTA YKT6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HNRH1 RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26760575 22939629
NAGK HNRH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HNRH1 YKT6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17643375 26760575
YKT6 AASD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB YKT6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
STX11 YKT6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
YKT6 C1QRF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
AP3M2 AP3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 AP3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 27424887
AP3M2 AP3D1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP3M1 AP3M2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STX12 BET1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
GOSR1 BET1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11927603 12388752
MATR3 COPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29884807 26496610
CPSF6 PNN â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RHOB EPHA7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
EXOC1 VPS53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STX11 EXOC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 LMNB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
RHOB NSF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB STX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB ROR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
STX11 VTI1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HNRNPC SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SF3A1 SF3B5 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
STX12 VTI1B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ACIN1 SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PNN SF3A1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SF3A1 SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPC PNN â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NAPA STX6 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HNRNPL SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SAP18 SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ARF1 COPB1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
STX7 GOSR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX6 SCFD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 34079125
STX6 STX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PGTB2 YKT6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MATR3 HNRH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
ACHA9 YKT6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ACHA9 ST7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AR6P6 YKT6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
T2R41 YKT6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FNTB YKT6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX3 YKT6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B AP3B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B AP3M1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX12 GOSR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
VTI1B IPO9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LMNA STX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24623722 24927568 34079125
MATR3 RBM14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
VTI1B STX12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX12 TBK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX12 STX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX3 TBK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX5 TNPO3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SAP18 SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CCDC132 VPS53 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA1 HNRNPA3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BCAS2 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SNRNP40 SNRNP70 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
SAFB SNRNP70 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SAFB SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RBM14 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BET1 GOSR2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRAF MAPK1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
RBM14 SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
GOSR1 YKT6 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
LMNA TPR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 22412018
GSK3B SFPQ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30711629 20932480
BET1 YKT6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 33961781
USO1 BET1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 11927603
BET1 VTI1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 33961781
BET1 SCFD1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 33961781
GOSR1 NSF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9325254 8636227 20562859
CPSF6 HNRNPL â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR10 DCTN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPL RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SF3A1 SNRPF â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPC SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RABGGTB YKT6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
VPS51 VPS53 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PNN SNRNP70 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
GOSR2 SEC22B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
RABGGTA RABGGTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
HNRNPA1 SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RBM14 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACIN1 PNN â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
GOSR1 SEC22B â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ACTR10 DYNC1H1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HNRNPC RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HNRNPA3 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA1 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SAFB SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BET1L STX5 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
GOSR1 STX6 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
BET1 STX5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
HNRNPA1 SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPC SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA3 HNRNPC â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HNRNPL SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BCAS2 SNRNP40 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SNRNP40 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA1 SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RNPC3 SNRPF â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HNRNPA3 HNRNPL â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BCAS2 SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
VPS35 SNX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11102511 16189514 26344197
HNRNPA3 SAFB â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SAP18 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SEC22B SEC24A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
INSR PTPN11 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
SFPQ SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RBM14 SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SAFB SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HNRNPC HNRNPL â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
VTI1A STX7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 11101518
STX7 STX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
STX7 STX5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
STX7 STX12 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
NSF STX6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 34079125 20562859
STX6 STX5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
HRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591642
HRAS BRAF â—¼   PROXIMITY ✅ 0.87 0.87 mint 30194290
EIF4A1 EIF4A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EXOC1 EXOC4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
STX11 TBK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21988832
HNRNPA1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA1 HNRNPL â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
STX7 VTI1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HNRNPA1 HNRNPC â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NAPA SEC22B â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BCAS2 SNRPB â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NAPA STX5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SNRNP40 SNRPB â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA3 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
SF3A1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
STX6 STX7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HNRNPL SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPC SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HNRNPC SF3A1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RAB3GAP1 RAB3GAP2 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
AP3B1 AP3M2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPC SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ACTR10 ACTR1A â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ACLY GSK3B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10653665 30711629 17353931
STX7 BET1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 33961781 26344197
VTI1B STX6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27791468 26186194 28514442 34079125
GOSR1 BET1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 11927603 33961781
COPG1 COPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 14729954 26344197 22939629 28514442 9751720
GOSR1 USO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11927603 16189514
HNRNPA1 HNRNPL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SF3A1 SNRNP40 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EIF2B5 STX11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GOSR2 STX6 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
PGTB2 PTAR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
USO1 SCFD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10903204 11927603
RBM14 SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EXOC1 EXOC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
VPS51 VPS53 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
AP3B1 AP3M1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
PTAR1 RABGGTB â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
LMNA LMNB1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
SEC24A SAR1B â—¼   GTPASE_REACTION ✅ 3.0 0.9 Reactome 10982397 10825291 17316621
GSK3A SFPQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20932480
GSK3B VPS51 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B ROR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21078818
GSK3B SNRNP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17570479 17353931
SCFD1 SEC22B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
STX6 STX12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17159904 26186194 28514442 34079125
BRAF MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
EIF2B1 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10805739 21795329 9446619
EXOC4 EXOC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 17043677 31413325 90000000 19889837 28514442 19885391
FNTB HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15451670 24294527 2217184
GOSR2 USO1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10903204 11927603 16189514
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
NRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
LMNB1 LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21346760 32814053 25948554 11792809 31467278 34079125 19727227 24623722 30419336 21988832 22412018 26524528 26264872 29568061 16189514 29997244 30021884
MAPK1 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP3K3 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAP3K3 MAPK1 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
PPP2R5D MAP3K3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
MAPKAPK2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
RCC1 NUDT21 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RCC1 TUBB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STX12 VTI1A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
USO1 STX5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10903204 11927603 16189514
NAPA VTI1B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
BCAS2 SNRPF â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ACTR1A DYNC1H1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
EIF4A2 EIF4G1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
STX5 YKT6 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CCDC132 VPS51 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
MAPK1 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
STX7 VTI1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ACTR10 DCTN1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
AP3D1 AP3M2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ACIN1 SAP18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
PTAR1 YKT6 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ABCE1 RPS3 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STX12 STX6 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
STX6 VTI1B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
COPB2 COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
CCDC132 VPS53 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
COPA COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
STX12 VPS33A â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
ABCF3 GCN1L1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
BCAS2 SNRNP40 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
BRAF KRAS â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
VIPAS39 VPS33B â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
SEC23B SEC24A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
STX6 VPS51 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
VPS33A YKT6 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS33A VTI1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS33A VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VTI1A YKT6 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NAPA STX7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
NAPA STX12 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
STX6 VTI1A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EEF2 RPS3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SNX1 VPS35 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
SF3B5 SNRPB â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SF3A1 SNRPB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SF3A1 SF3B5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SF3B5 SNRPF â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
BRAF NRAS â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SNRNP40 SNRPF â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
GOSR2 STX5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
GOSR1 STX5 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PNN SAP18 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BRAF HRAS â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
EIF4G1 EIF4A1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219000 16932749
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NAPA NSF â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPA COPG1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP6C PPP6R1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
AP3B1 ARF1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPB2 COPG1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SEC22B STX5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CPSF6 NUDT21 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
VPS33B VIPAS39 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 29778605
VIPAS39 VPS33B â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 8380380 22677173
SNRNP70 SNRPF â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DCTN1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MAP2K2 MAPK1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
SF3A1 SNRPF â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PGTB2 PGTA â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 32296183 26344197 26186194 28514442
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SNRNP70 SNRPB â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
DYNC1H1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SCFD1 STX5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF4A1 EIF4G1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SNRPB SNRPF â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF2B2 EIF2B4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B2 EIF2B5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B4 EIF2B5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
USO1 SEC24A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10903204 11306556 23378591 9150144 10679020 11285137 23698585 11927603 16624868
MAPK1 TPR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12594221 18794356 22028470
IGF1R CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 10026153
PPP2R5D GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3A EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 19651622 19007248 17081983 20166139 9468292 18691976 18088087 11500362 19664994 20068231 18452278 18707149 12133000 16097034 19413330 18669648 15302935
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
PPP2R5D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3B ACLY â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17145710 20058876 10653665 17353931 2176822
GSK3B SFPQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20932480
GSK3B EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 19007248 17081983 20166139 12133000 21798082 19413330 15302935 18701453 24023715 20068231 18452278 17570479 18669648 9468292 18691976 18088087 19651622 11500362 19664994 16097034 18707149
USO1 SEC22B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10903204 11306556 23378591 9150144 10679020 11285137 23698585 11927603 16624868
SEC22B SAR1B â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22013193 10982397 23378591 20545907 18843296 10825291 20679433 11035026
SEC22B NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
STX6 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
STX6 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
GOSR2 YKT6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22013193 19758564 24119662 19164740
GOLIM4 YKT6 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
YKT6 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
YKT6 GOLGA5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
DYNC1H1 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
GOLGA5 BET1L â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOLIM4 BET1L â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
CUX1 BET1L â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
KRAS BRAF â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 24937142 16294014 12932339 7744815 9020159 15035987 16364920 11325826 16041367 24347342 12932319 10205168 21441910 23993095
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
KRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 23331499 19541618 8601312 14970219 18567582 16135787 12932319 17563371 12917261 19933846 21779497 17635919 19223544 15710605 8073291
NRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 21478863 9368069 19541618 8601312 14970219 18567582 16135787 7935411 12932319 12917261 17563371 19933846 21779497 8073291 15710605
RHEB BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19651622 20166139 16803888 18691976 20068231 18452278 12214276 15150271 18669648
MAPK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14654779 21478863 19541618 16508002 19710016 19933846 15664191 29335436 8621729
HRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 7706312 14970219 18567582 12932319 8073291 1386920 23331499 8601312 9154803 18988627 8668348 21779497 19541618 19933846 17563371 18098337 16803888 26165597 24441586 16135787 12917261 15710605 10545207
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
USO1 COPA â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 18283113 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
USO1 COPB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 18283113 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
USO1 COPB2 â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 18283113 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
USO1 COPG1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 18283113 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
GOSR1 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOLIM4 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
STX5 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
CUX1 GOLGA5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
PAFAH1B1 DYNC1H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11889140 11163259 27173435 12885786 19622634 26496610 36692009
EIF2B1 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B1 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B4 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25910212 10805739 31515488 16189514 32296183 9446619
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
NRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FGFR4 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR4 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
GDI1 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI1 RAB3GAP2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
GDI1 RAB3GAP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
GDI2 RAB3GAP2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
GDI2 RAB3GAP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
STX5 GOLGA5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOLIM4 STX5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOSR2 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
GOSR2 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
HRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
HSP90AA1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10744744 17145710 12441346 14743216
PTPN11 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28065597 23331499 11779860 7642582 10082579 8895367
PTPN12 INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10734133 19167335 8454633
INSR PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8135823 9832615 7493946 9593725
KRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
MAPK1 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAP2K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 21675959 11704645 9694850 17081983 7565670 12750173 19690332 12932319 11823456 18799465 15592455 11337027 18083107 21365009 12788955 11134045 19219045 17389395 9447970 15342917 23331499 19534553 17569879 7559390 23047924 8226933 8223433 17272394 15851026 15811950 19494114 18988627 18669648 11549292 23519423 19541618 18691976 1381507 16293107 17906627 11986622 19933846 8376945 19053285 16094384 11971971 17192257 11136732 11948414 8388392 7898932 9731057 11730323 18039929 11118451 19369195 12920017 15951569 15466214 10746662
NRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
SNCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11279280 12121974
RET MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 19901323 11522789 91184134 16156666 16497976 15592455 12571246 19415658 11826406 17389395 18578522 21109534 20068231 18452278 18669648 16153436 11522288 18691976 1378617 15972258 15935618 16094384 12388769 11971971 19651622 21842857 28450419 18707149 17016520 21455180
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21675959 22028470 15094067 8846784 23047924 25255283 12861023 7592979 1327754 8995385
MAPK1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15950189 22028470
NRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
RET MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 551.0 1.0 Omnipath 15956760 25485910 17240116 20385359 12527803 17621270 23612968 18212246 21860413 18097051 18851832 10645003 25679764 21423210 15007380 19934253 19935718 22356909 9677429 15781651 10849428 17188005 20667468 14625304 34380633 17377139 21423211 20010870 26186445 20736304 12376318 33627405 16740736 21561860 15004239 17901130 15212956 15897464 15143154 18819921 17157789 26297582 12138104 11777927 22158866 23195225 34473994 20494825 14963038 16778204 17391526 27683117 22689060 12444552 31933886 15059947 26823016 15657432 19377875 17142325 15486045 21460222 23431142 11159838 27654866 19941816 14718389 34375550 18593598 17360704 23997214 24501773 16163708 10604992 15297577 17106060 24396487 25893857 20361349 16822962 12554776 18454177 29434871 34530870 16141331 12356731 19169277 20543098 17685427 21478906 18463290 16250012 20534535 21228323 7535768 26617336 15963258 10617652 17196532 19995915 10464310 15315965 12082540 21685939 25730857 18305109 25703330 16928771 15681433 11083859 16076871 20395206 23146907 26246800 21454539 12660819 21220474 15866871 15637081 19858202 34403210 18032526 16195541 21829454 16459330 17209045 12808105 11585739 16162500 25833830 18246127 11864968 24418169 15935618 19925796 20160123 17056593 14998784 18215133 10508618 18775330 18760948 12952943 21768338 17317777 8155326 22258404 15788397 26919095 28213521 21192818 33798093 15851026 26242183 12402043 21868357 17064352 20927383 16380505 15035987 21454675 18957207 19193766 21188622 19050043 16904111 19888469 26073130 20185553 15282551 16790523 23405013 11994288 17510392 32081857 18941537 20930115 19106095 11043579 21499301 20145126 24427291 10958690 15939799 19088846 19286657 18424438 15308678 18198175 27323814 24338688 24252946 19956644 21478903 12014987 23017243 17525129 12511559 17615152 16505244 20122898 12077249 17123942 26035354 11278407 15665049 20531297 17292825 14976148 16449644 16461767 23361053 19261611 11502744 25658205 12149254 30327409 17560175 24352879 26586479 26804906 25779944 34125833 19118012 11352917 16740725 11884401 16464862 16641227 27323830 18063582 22955283 24561529 10779765 10542198 16135812 23564461 17210721 24469048 24803537 21602434 17110601 21045017 11073973 10597231 23687376 34556812 17341659 18692468 17579083 12384403 21408150 25417160 11752053 23325789 17371847 11970985 22327338 26265441 16840783 17283152 26616862 23188829 17239630 21487005 11024037 17053147 24363437 25682201 20234004 12391272 23644655 25638159 20808799 17922836 20129247 24913355 18451171 25483104 26296889 21081844 17404396 11287604 18263590 26317416 15541367 16467309 12765939 16331263 16498402 20485667 11230338 16387841 19543320 7687743 20228268 15630487 16774943 16710359 10803464 16844778 16574647 15994317 17495961 21215800 17590453 26382850 19002495 12909616 20599567 12558965 10667594 24711455 17255109 16038803 12370087 21072043 20008839 18805968 10206983 11875080 20231899 21499296 21908610 16002410 12821943 24292678 17525735 17928416 21057531 25236495 17283137 21659545 24403530 16919488 23378338 22973961 18847491 16682955 20840866 16153436 23542175 24492000 12526087 26556867 12133965 12433918 20065107 14610044 11959800 15580310 21730285 11046056 9124279 14707024 26725216 16452220 22212957 25811962 15696170 11416124 20498373 17157787 21653826 16149052 20022946 34262144 16434970 10558990 18045996 10925301 16280323 25581518 15899879 21441955 20566643 15466476 15657177 11706017 15059847 8444886 18519681 23528009 33513601 20138986 12368275 24608435 17062641 20082306 20375017 17537990 24567333 33820494 10712263 21278199 19011679 20145145 27582276 25640183 21730054 16177091 17250586 15879307 16728403 18299328 24269888 17303383 9482941 17671177 17173941 24095720 15304500 12874275 33828192 11827968 33731431 10799542 15328343 18838481 19036157 17634226 17110082 17855349 31722981 26079947 25002506 14559232 23584478 18593910 17114467 16373398 16931794 17016429 14676826 28415597 12029087 24269383 8626767 20478260 12097262 14764579 12181310 15100319 12384432 15271996 17562849 19036927 19326083 20072652 25940440 11922392 17913704 19494114 25596730 18938240 27449290 12897059 21478911 21123455 26804170 10940302 16624816 26876209 12048182 17150968 21478863 17307705 18658095 24995980 16582879 17289590 33667549 17209041 17890097 21726627 27662093 16843264 19426503 11103941 11940578 17906618 26234813 19029090 15007386 15958730 12576312 17667937 17785202 34480897 20647329 18941890 16446383 25562429 10867021 26985018 16413470 23178720 25578563 34437586 21738699 21258408 20388777 24681954 20459645 12242309 15289328 21575862 16185843 19147767 34497368 19153083 12124352 17371994 17567959 15611080 17297454 23012246 14557270 28542650 15713673 21129803 19460345 10958798 21772273 21900206 19205871 17591920 19217381 12963813 19718025 24469056 16624867 21149447 15728578 33902596 11971971 16455819 19112174 10751321 1835084 11016927 18267069 20410276 21980390 17409387 23831578 21477078 15558056
MAPK3 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20041225 15950189 21738525
MAPK3 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21675959 17242355 7592979 14499342 14967450 23583303
NSF VTI1A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
VTI1A VPS51 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
VPS53 VTI1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258