Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CSK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
CSK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
RAB39A RAB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NEK7 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEK7 RAB31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCK DDX19B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DCTN3 ACTR10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
DCTN3 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
BRAF PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
PEBP1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10490027
PAK2 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20936779
CSE1L PPP5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PGAM1 DCTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRPSAP1 DDX19B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAB7A DNM2 â—¼   COLOCALIZATION 2.0 0.8 intact 20711168 8045116
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EEF1A2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EEF1A2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
GDI2 RAB5A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPB1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18950704
IPO11 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PRKCE MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16810323 16461926
MAPK3 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15310280 10402467
PAK2 MYLK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10748018 10092231
UBA1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
PTK2B PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217348 15557335
RIPK1 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
PFKL TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
TIPRL PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17384681
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PRKAB1 PRKAA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6767403 18480843
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
PTPN11 TNFRSF14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12796776 16932752
RAB14 RAB39A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAB3IP RAB3IL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RABGGTB RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7991565 18532927
RIPK1 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2V1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1551980 11057907
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
MAPK14 MAPKAPK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 14499342
RAB11B RAB7A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ANKRD27 RAB32 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
ACTR1A DCTN3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
EEF1A1P5 EEF1A2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RAB1B RAB7A â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DCTN1 DCTN4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
COPB1 COPZ1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
OTUB1 TRAF6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20622874 34591986 19996094
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GDI1 RAB12 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
DCTN3 DCTN4 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
UBE2NL UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EIF2B2 EIF2B5 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
RAB8B RAB13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAB1B RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RAB6B RAB6A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BRAF HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 31980649
RIPK4 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 33961781
NUDT5 SKA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 33106477
RAB1A RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
SAR1A SAR1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MAPK14 MAPKAPK2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ACTR1A DCTN4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MON1A RAB7A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RAB8B RAB8A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26824392
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
MAPK3 HSPB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21575178 8774846 25241761
SOX2 PAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RIN3 RAB5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32552912 11733506 12972505
SOX2 USP9X â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31605775 23667531
ACTR10 DCTN3 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MAP3K7 RIPK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SAR1A SAR1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RIPK4 UBA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26972000 32707033
ACTR10 DCTN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RABGGTB YKT6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
KIF5B TUBA1B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RAB11B RAB8A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RABGGTA RABGGTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR10 DYNC1H1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RAB31 RABGGTA â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
RAB32 RAB38 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 31552791
RAB7A RAB4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10329441 16962593 34079125
RAB5A RAB7A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
ACTR1A DCTN3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
GDI2 RAB7A â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
GDI1 RAB6A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
KIF5B TUBB2A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
RAB11A RAB1B â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
RAB11A RAB5A â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
ARF6 RAB1A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939626 34079125
RAB1B RAB1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 26344197
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
FN1 VHL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RAB1A RAB1B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAB1B RAB8A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAP3K7 TRAF2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RAB3IL1 RAB3IP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PPP2R1A PPP2R4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
GDI1 RAB8B â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ACTR10 ACTR1A â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RAB10 RAB8A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 17353931
RAB5C RAB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
RAB5C RAB1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
RAB7A RAB5C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
GDI1 RAB11B â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
GDI2 RAB11B â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
RAB11B RAB1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
GART PAICS â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
TRAF6 UBE2V1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAB6A DCTN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16902405 12401177 16473624
RAB11A RAB1A â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RAB7A RAB2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 26344197 34079125
TRAF2 UBE2N â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RAB11A RAB7A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
AP3B1 AP3M1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
DCTN1 DCTN3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
GDI1 RAB7A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PSMG1 PSMG2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
FN1 CSK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
ARF6 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
TUBB3 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
DCTN4 DCTN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 28718761 26638075 28514442 34079125
YWHAE DENND1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 26055712 22762500 23684622
DENND5A PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF2B1 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10805739 21795329 9446619
RPS6KB1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19593530
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
PPP5C MAP3K7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP6C MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
PPP2CA MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
UBE2N MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17965022 17079228 10702308
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
MAPKAPK2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
MAPKAPK2 TRAF2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
PPP2CA TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
RAB8A RAB3IP â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17574030 22653444 17646400
STK38 RAB3IP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22445341
UBE2N TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18981220 14713952
PSMG1 PSMG2 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
GDI2 RAB8B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DENND1A RAB35 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACTR1A DYNC1H1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
TRAF6 MAP3K7 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18758450
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
ACTR10 DCTN1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
RAB1B RAB8B â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
GDI1 RAB1B â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RAB3IP RAB8A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
GDI2 RAB8A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
COPB2 COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
GDI1 RAB8A â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HSPB1 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
TUBA1B TUBB2A â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
RAB1A RAB7A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17728241
ABCF3 GCN1L1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RAB7A RAB5A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 10329441 22939629 26344197 34079125
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
TBCD TBCE â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
COPG1 COPZ1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
GDI2 RAB1B â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
RAB11B RAB1B â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
DCTN1 DCTN4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
GDI1 RAB1A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
RAB5C RAB5A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17353931 26496610 28514442 34079125
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
GDI2 RAB1A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
RAB11A RAB3IP â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPB1 COPZ1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPB2 COPZ1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
COPB2 COPG1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ACTR1A DCTN4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PPP2CA TIPRL â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MAPK14 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ACTR10 DCTN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ETF1 GSPT1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MAP3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF2B2 EIF2B5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RAB3A MADD â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 1845915 27246931 7911226 20937701 21776405 16571673 25341920 11516400 12244319 9136770 9020086 8144603
RAB3A RAB3IL1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 1845915 27246931 7911226 20937701 21776405 16571673 25341920 11516400 12244319 9136770 9020086 8144603
RABGGTB RAB3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18532927 7991565 8706741 12535645
PPP2R5D GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3A EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 19651622 19007248 17081983 20166139 9468292 18691976 18088087 11500362 19664994 20068231 18452278 18707149 12133000 16097034 19413330 18669648 15302935
RAB10 DENND4A â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 27246931 20937701 25341920 18076383 17132146 23713133 23263280 7688123 16641372 22908308
RAB10 DENND4C â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 27246931 20937701 25341920 18076383 17132146 23713133 23263280 7688123 16641372 22908308
RAB32 HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
COPB2 RAB1B â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
COPZ1 RAB1B â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
COPB1 RAB1B â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
RAB1B COPG1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
RAB6A RIC1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15029241 16571679 17451557 22335553 24794632 10865125 11689439 9050864 10990452 23437303 23091056 15758030 15483056
GDI1 RIC1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 27246931 19620288 19109890 21183348 11689439 10990452 25341920 15878329 23091056 18367545 21421921
RAB6A RIC1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 27246931 19620288 19109890 21183348 11689439 10990452 25341920 15878329 23091056 18367545 21421921
GDI2 RIC1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 27246931 19620288 19109890 21183348 11689439 10990452 25341920 15878329 23091056 18367545 21421921
DYNC1H1 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RAB6A ACTR10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
RAB6A ACTR1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
GDI2 ANKRD27 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 27246931 22171327 16754960 16525121 15561770 26925400 22648168 27103185 25648148 18804435 22705394 19745841
ANKRD27 RAB21 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 27246931 22171327 16754960 16525121 15561770 26925400 22648168 27103185 25648148 18804435 22705394 19745841
GDI1 ANKRD27 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 27246931 22171327 16754960 16525121 15561770 26925400 22648168 27103185 25648148 18804435 22705394 19745841
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
GDI2 CCZ1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20851765 23084991 23220125 27246931 12364329 11179213 2115402 23351085 20305638 8522602 12944476 25341920 23645161 21683469 9020161 15138286 20797862 20434987
RAB7A CCZ1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20851765 23084991 23220125 27246931 12364329 11179213 2115402 23351085 20305638 8522602 12944476 25341920 23645161 21683469 9020161 15138286 20797862 20434987
GDI1 CCZ1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20851765 23084991 23220125 27246931 12364329 11179213 2115402 23351085 20305638 8522602 12944476 25341920 23645161 21683469 9020161 15138286 20797862 20434987
DCTN3 RAB6A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
DCTN3 DYNC1H1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RAB6A DCTN4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
GDI1 DENND1A â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 DENND1A â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
RAB35 DENND1A â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 DENND1B â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
RAB35 DENND1B â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI1 DENND1B â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
RAB35 DENND1C â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI1 DENND1C â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 DENND1C â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 DENND2A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 27246931 19490898 25343031 20937701 19620288 25341920 9590177 18367545 21421921
GDI1 DENND2A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 27246931 19490898 25343031 20937701 19620288 25341920 9590177 18367545 21421921
RAB9A DENND2A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 27246931 19490898 25343031 20937701 19620288 25341920 9590177 18367545 21421921
GDI1 DENND4A â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 27246931 20937701 25341920 18076383 17132146 23713133 23263280 7688123 16641372 22908308
GDI2 DENND4A â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 27246931 20937701 25341920 18076383 17132146 23713133 23263280 7688123 16641372 22908308
GDI1 DENND4C â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 27246931 20937701 25341920 18076383 17132146 23713133 23263280 7688123 16641372 22908308
GDI2 DENND4C â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 27246931 20937701 25341920 18076383 17132146 23713133 23263280 7688123 16641372 22908308
GDI1 DENND5A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20159109 20937701 22581368 12684051 23239882 23839779
RAB39A DENND5A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20159109 20937701 22581368 12684051 23239882 23839779
GDI2 DENND5A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20159109 20937701 22581368 12684051 23239882 23839779
RAB39A DENND5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20159109 20937701 22581368 12684051 23239882 23839779
GDI1 DENND5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20159109 20937701 22581368 12684051 23239882 23839779
GDI2 DENND5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20159109 20937701 22581368 12684051 23239882 23839779
RAB14 DENND6A â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 12475894 26936971 27246931 23444368 22595670 20592283 25341920 24694596 15692570 15958533
GDI1 DENND6A â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 12475894 26936971 27246931 23444368 22595670 20592283 25341920 24694596 15692570 15958533
GDI2 DENND6A â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 12475894 26936971 27246931 23444368 22595670 20592283 25341920 24694596 15692570 15958533
RAB14 DENND6B â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 12475894 26936971 27246931 23444368 22595670 20592283 25341920 24694596 15692570 15958533
GDI1 DENND6B â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 12475894 26936971 27246931 23444368 22595670 20592283 25341920 24694596 15692570 15958533
GDI2 DENND6B â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 12475894 26936971 27246931 23444368 22595670 20592283 25341920 24694596 15692570 15958533
RAB6A DYNC1H1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
EIF2B1 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B1 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
GDI1 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
RAB31 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI1 SBF2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 27246931 22171327 16754960 16525121 15561770 26925400 22648168 27103185 25648148 18804435 22705394 19745841
GDI1 MON1A â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20851765 23084991 23220125 27246931 12364329 11179213 2115402 23351085 20305638 8522602 12944476 25341920 23645161 21683469 9020161 15138286 20797862 20434987
GDI1 MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
GDI1 RIN3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI1 RAB3GAP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
GDI1 HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
GDI1 RAB3IL1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 1845915 27246931 7911226 20937701 21776405 16571673 25341920 11516400 12244319 9136770 9020086 8144603
GDI1 RAB3IP â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 17574030 8408203 27246931 20308558 20937701 21216617 22433857 21041651 24296415 22983554 17208202 18701652 22653444 25341920 12221131 22365832 17646400 21273506
GDI1 YWHAE â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
GDI2 MON1A â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20851765 23084991 23220125 27246931 12364329 11179213 2115402 23351085 20305638 8522602 12944476 25341920 23645161 21683469 9020161 15138286 20797862 20434987
GDI2 HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
GDI2 RAB3GAP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
GDI2 RAB3IL1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 1845915 27246931 7911226 20937701 21776405 16571673 25341920 11516400 12244319 9136770 9020086 8144603
GDI2 SBF2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 27246931 22171327 16754960 16525121 15561770 26925400 22648168 27103185 25648148 18804435 22705394 19745841
GDI2 RIN3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI2 YWHAE â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 RAB3IP â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 17574030 8408203 27246931 20308558 20937701 21216617 22433857 21041651 24296415 22983554 17208202 18701652 22653444 25341920 12221131 22365832 17646400 21273506
RAB38 HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
HSP90AA1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10744744 17145710 12441346 14743216
MAPKAPK2 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 150.0 1.0 Omnipath 17081983 16565220 11839738 19562805 19166925 19415658 32570757 25257914 20626350 17170118 26887051 11042204 11383510 25241761 21575178 24421331 14499342 19651622 19691289 17924679 25728673 20044836 21423207 18707149 16964243 19007248 15581903 17576778 12096113 11844797 8774846 18669648 12829704 12740362 12377770 18691976 15682460 16840785 8995385 18477563 14612593 19369195 10978313 18720982 18212344 17697330 1332886 18767875 18326031 18187866 19664995 15302935 21245386 15850461 14717697 20068231 25675293 93076920 1730670 21357508 18088087 7799959 10383393 20886841 23950959 12367505 29330367 28460458 20166139 15728188 20230923 21989268 19413330 16840786 14688255 18578522 25048900 15976317 21131586 23112078 18950704 20058876 19597476 16097034 19664994 11274345
RAB27A MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK14 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
TRAF6 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF2 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12547194 20038579 14633987 14743216 17384642
TRAF6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 19675569 17947236 19843958 10882101 19521662 11259596 17079228 28024152 31885808 19112497 22924441 10094049 27501752 18922473 11518704 11809792 16517750 19232515 10702308 16410796 14633987 19820695 22851693 10921914 18758450 12496252 12609980 21822258 12242293 25963657 24434549 27249171 22643835 21245467 17965022 26038599
PEBP1 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11585904 23331499 23180781
PPP2CA MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18299321 17079228
PPP6C MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17079228
MAP3K7 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
MAP3K7 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 20615388 18692468 15980064
MAP3K7 RAB8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 34088839 32227113 32017888 31292254 32601174 33887226 30709905
MAP3K7 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12589052 17965022 15692051 17947236
TRAF2 MAP4K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9712898 16713569
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK13 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
TRAF6 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAPK14 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 21675959 16456544 23602568 17395714 21988832 10581204 23331499 21071413 27898710 23047924 10922375 12738796 11551945 26496610 25852190 18988627 15629715 18669648 15187187 11042204 26186194 25241761 8846784 17906627 14499342 9922370 7923353 9768359 18039929 25255283 7592979 17255097 11274345 23455922
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
MAPK3 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21675959 17242355 7592979 14499342 14967450 23583303
RAB7A MON1A â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20851765 23084991 23220125 27246931 12364329 11179213 2115402 23351085 20305638 8522602 12944476 25341920 23645161 21683469 9020161 15138286 20797862 20434987
PAK2 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 2160950 18088087 10748018
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
PRKCZ PEBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20166139 10891480 20068231 12551925 14654844
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16109716 2826472 16899564 11438723 11124802 10200280
PRKAA1 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 18480843 8626596 17728241 21232561 16306228 8663446 25852190 8621713 23455922
PRKCE PRKD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12058027
PTPN11 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10880513
RAB8A RAB11A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20308558 22433857 22983554 12221131 23567335 21273506
RAB4A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
RAB5A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
RAB3GAP1 RAB18 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 9030515 15914536 17488286
RAB3GAP1 RAB18 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 9733780 23333653 18664496 24891604 16207721 23176487 9030515 15914536 17488286 23420520
SBF2 RAB21 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 27246931 22171327 16754960 16525121 15561770 26925400 22648168 27103185 25648148 18804435 22705394 19745841
RAB31 RIN3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
YWHAE RAB35 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
RAB3IP RAB8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12221131 26918858 26258637 26824392 21273506 27173435 16189514 20308558 123217
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TNFRSF14 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17353931 9153189 19332782 9162022 16713569
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215