Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
YWHAG GSK3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAZ CSE1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CSE1L YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CSNK1A1 ETF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12062430 5215475
CSNK1A1 YWHAZ â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12062430 5215475
CSNK1E YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7264069 19860830
YWHAZ DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PPP2R1A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
EEF2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ EIF4A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ GAPVD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
GAPVD1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ GDI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
GDI2 RAB5A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
IPO11 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
TIPRL PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17384681
PPP2CA RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15950189
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP6R1 PPP6C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208117 16769727
PTPN11 VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 12577067
RABGGTB RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7991565 18532927
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAH TSC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12438239 5215924
TUBA1B YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAG USP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
VAV2 CBL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11262396 20940296 15345594 11313921
VIPAS39 VPS33B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PPP6C PPP6R3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
BRAF HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 31980649
NAA15 NAA20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16507339 26344197
YWHAZ USP8 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217040 15161933
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RABGGTB YKT6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR10 DYNC1H1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
EPCAM SPINT1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
TUBGCP2 TUBGCP3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CBL VAV2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
EIF4A1 EIF4A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NAA25 NAA20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 18570629
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PPP2R1A PPP2R4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
YWHAB BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
CHML RAB5A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
TSC2 YWHAB â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AP3B1 AP3M1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
TSC2 YWHAZ â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
YWHAG BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
PPP2CA TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAZ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217040 15161933
ABCE1 RPS3 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
YWHAZ TSC2 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 12438239 5215924
ABCF3 GCN1L1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
USP8 YWHAZ â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
VIPAS39 VPS33B â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
YWHAB TSC2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 12438239 5215924
EEF2 RPS3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PPP6C PPP6R3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP6C PPP6R1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ELP4 IKBKAP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EEA1 RAB5A â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
BRAF YWHAZ â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PPP2CA TIPRL â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
ELP2 ELP4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
VPS33B VIPAS39 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 29778605
VIPAS39 VPS33B â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 8380380 22677173
DYNC1H1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ELP2 IKBKAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ETF1 GSPT1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NAA20 NAA25 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2R5D GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3A TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16959574 20226003
DYNC1H1 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
YWHAH BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8085158 8085159 10931830 7744815 8668348
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
BRAF YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 17353931 15324660
BRAF YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 17353931 8668348 15324660 15161933
BRAF YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12620389 17353931 24255178 15324660 10931830
CHM GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
CHML RABGGTB â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11675392 22694141 16401880 11141079 8513495 18532927
CHML GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
CSNK1A1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 14613942 19651622 17081983 15119949 18691976 20068231 18452278 9360956 16045749 12062430 18077418 19415658
PAFAH1B1 DYNC1H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11889140 11163259 27173435 12885786 19622634 26496610 36692009
RAB5A EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15328530 17145710 20534488 14600265 11718716 10491193 11493665 11870209 16902405 15016378 10720461 9697774
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
GDI1 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
RAB31 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
TUBGCP2 TUBGCP3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139