Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
ECPAS PCM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LRP6 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16273260 23371553
LRP6 DVL2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 16273260 23371553
MBP ADRB2 â—¼   PROXIMITY 2.0 0.8 intact 28298427 20167430
ADRB2 RAB14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ALS2 RAB5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8088034 21300063
APPL1 RAB22A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220032 17581628
RAB5A APPL1 â—¼   COLOCALIZATION 2.0 0.8 intact 5220032 17581628
APPL1 LRP2 â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
HNRNPM EEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RSPO3 EEA1 â—¼   COLOCALIZATION 2.0 0.8 intact 8297435 21909076
EEA1 IGF2R â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
EEA1 LRP2 â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
EEA1 TOM1L1 â—¼   COLOCALIZATION 2.0 0.8 intact 19798056 7980429
EEA1 KIF16B â—¼   COLOCALIZATION 2.0 0.8 intact 5225323 17641687
EEA1 RAB14 â—¼   COLOCALIZATION 2.0 0.8 intact 5219066 16962593
TOM1L1 EGFR â—¼   COLOCALIZATION 2.0 0.8 intact 19798056 7980429
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TCP1 GBA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21098288 1014376107
GTPBP4 TMA16 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PLEKHF2 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PTPN23 ZFYVE9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RAB14 RUFY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20534812
USP8 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
TP53 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7711923 20206173
RABEP1 RABGEF1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PTPN23 ZFYVE16 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EEA1 RAB5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12493736 10491193
VPS35 WASH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29893854 24980502
FCG2A EEA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
PAI2 EEA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AF17 EEA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BMI1 RRP12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 EEA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
NUPL1 EEA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
IGF1R ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 17307140
EEA1 RABE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10458612 10720461
CFTR RAB5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26618866 19398555 21455491
PCM1 HAUS6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26638075 24981860 34079125
RUFY1 RUFY2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
VPS11 VPS16 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RAB5A APPL1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220032 17581628
APPL1 RAB5A â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 5220032 17581628
RAB5A RUFY1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14617813 34079125
VPS11 VPS18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
VPS16 VPS18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PCM1 TPGS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26638075 34079125
EGFR USP8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
C11ORF49 LRRC49 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR TNK2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR SFN â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR PDCD6IP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MAPK14 TP53 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
APPL1 RAB5A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EEA1 RAB5C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25266290 12493736 25114243 34079125
TP53 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11437382 15132979 14570892
RABGEF1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11452015 27411398 19759177
TOM1L1 VCP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
RABGEF1 RAB5A â—¼   PHYSICAL_INTERACTION ✅ + 0.92 0.92 Signor 11452015
RABGEF1 RAB5A â—¼   GTPASE_REACTION ✅ + 0.92 0.92 Signor 27411398
TGFBRAP1 VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS16 VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS18 VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
ABCE1 RPS29 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
VPS16 VPS11 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 11382755 26496610 23901104 26463206
RAB5C RAB5A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17353931 26496610 28514442 34079125
SEC13 SEC16A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
RABE1 RAB5A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10720461 11718716 26430212 9045618 9524117 15328530 8521472 15378032 34079125
RAB5A RABGEF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
TGFBRAP1 VPS18 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SFN TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EEA1 RAB5A â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RAB5A RABEP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
FLT1 KDR â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TGFBRAP1 VPS16 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
VPS11 VPS16 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
VPS11 VPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS11 VPS39 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS16 VPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
TGFBRAP1 VPS11 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RABEP1 RABGEF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
DVL2 LRP6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
MBP PLP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 2467009 6083474 16713569
LRP6 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
MAPK14 EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16138080
RAB5A EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15328530 17145710 20534488 14600265 11718716 10491193 11493665 11870209 16902405 15016378 10720461 9697774
RAB5C EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25266290 12493736 25114243
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
PDCD6IP EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 31980649 15456872 12771190 24658140 15557335 25402006
MAPK14 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15187187 18039929 19138820 7535770 12738796 17139251 16932740 23397142 16785992 11274345
USP8 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 16120644 25853104 20736164
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR TNK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 20359967 8647288 20432460 17182860 15951569 8497321
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
RAB31 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GZMB IGF2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11081635
TP53 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15131018 11001824 12089352 20633551 24205274 17097318 10023442 17600529 17014845 8710868 12444079 16181796 22033326
VCP KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
MAPK14 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 21675959 26247731 20213747 17535811 20506250 15657900 9315650 15642743 19413330 11283254 22975381 10581258 16083285 1088347 21614932 16393692 10884347 21050851 16552184 10747897 15187187 17906639 25789565 15140942 11258706 24818748 19436832 10781582 10212189 17172861 10348343 11078726 11274345
RAB5A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
RABEP1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15328530 17145710 10720461 11452015 11718716 8521472 26430212 9524117 15378032 9045618
RABEP1 RABGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17450153 26430212 24957337 12505986 9323142 17341663 11452015 10720461
TP53 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18281511 10101800 22427654 12640112 17404570 12447694 17361185
TP53 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20206173 17546054 18431400 21340684 20066118 20457558 20182602 11896572 6396087 14517281 21625211
TP53 KDR â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368