ADIPOR2
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16622416
|
PRKCZ
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
18650932
7232391
|
APPL2
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CASP9
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12011067
11248093
|
OCRL
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8184127
21378754
|
DCC
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12011067
11248093
|
APPL1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
APPL1
|
RAB22A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220032
17581628
|
AR
|
APPL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12621049
20610535
|
RAB5A
|
APPL1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5220032
17581628
|
APPL1
|
LRP2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21971085
8306957
|
APPL1
|
DCC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12011067
|
RAB22A
|
APPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AR
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19481544
7103716
|
AR
|
TUBB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12775765
21734264
|
MYCBP2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
32814769
|
AR
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12933816
|
ARIH2
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
DCC
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0901767106
19721007
|
CBL
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLB
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLB
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLB
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
EPHA2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0808987105
18948590
|
HDAC1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19166851
6823802
|
CTNNB1
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16219695
|
NTRK2
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001478
23424281
|
HSPB1
|
DPYSL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
EEA1
|
LRP2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21971085
8306957
|
EGFR
|
SH2D2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
TP53
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
EGFR
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
1845983
|
TP53
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
EPHA2
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
7982920
|
ID1
|
FGFR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16557594
21876767
|
RELA
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11931769
5215238
|
RELA
|
HDAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23027620
|
HDAC3
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16847267
0510834103
|
TP53
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HSPB1
|
KLF15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPB1
|
UBE2N
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18950704
|
PIK3R1
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
6730400
7589433
|
IGF1R
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
7541045
|
RELA
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11909978
15517885
|
LRP2
|
OCRL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21971085
8306957
|
PIK3R1
|
NTRK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6730539
8226808
|
NTRK1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8226808
8384556
|
RAB5A
|
OCRL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
16902405
5218938
|
RAB5A
|
OCRL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5218938
16902405
|
OCRL
|
RAB5A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
16902405
5218938
|
TGOLN2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PLEKHF2
|
PRPSAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PNMA5
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219546
17245430
|
TP53
|
PRKAB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
PRKCZ
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
12881425
5216561
|
TP53
|
PRNP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24339999
19064990
|
TRAF2
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TP53
|
STK11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17108107
21317932
|
TP53
|
STK11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23995788
21317932
|
UBE2V1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1551980
11057907
|
UBE2V1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213148
11057907
|
CBLB
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
IGF1R
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
FGFR1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
TUBB4B
|
UBE2V1
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
PIK3R1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
16273093
5218056
|
UBE2N
|
UBE2V1
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
GATAD2B
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
PDGFRA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
TUBB2A
|
TUBB4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.81
|
STRING
|
36370105
|
AKT2
|
UBE2O
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
NTRK1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21570973
25921289
|
DACT1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21718540
18936100
|
DOK2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10508618
|
EGFR
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17047074
17307140
|
OCRL
|
RAB5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25107275
34079125
|
TUBB2A
|
TUBB4B
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
EGFR
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15657067
24797263
|
LYPD3
|
LPAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
LUC7L
|
UBE2O
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
AKT1
|
STK11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24412244
28205554
28628118
|
RAB5A
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
5220032
17581628
|
APPL1
|
RAB5A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.84
|
0.84
|
mint
|
5220032
17581628
|
CTNNB1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
KIF5B
|
TUBA1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
TUBA1B
|
TUBB4B
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
HSPB1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
AKT2
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
11546794
11278835
12149249
14500673
9736715
12176337
28514442
11445557
|
HDAC3
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
29523594
20026773
|
APPL2
|
RAB22A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
EPHA7
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
22036564
|
CBL
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
KIF5B
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
APPL1
|
PNMA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
AKT1
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
HDAC1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
NTRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
25402006
24658140
|
TRAF6
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
8153045
21516116
|
TRAF2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
HDAC2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
INO80E
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HDAC3
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
PIK3R1
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PPP2R1A
|
PPP2R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
TUBB3
|
TUBB4B
|
â—¼ CORRELATES
|
|
+
|
0.87
|
0.87
|
CCLE
|
31978347
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
EGFR
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
GATAD2B
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
GATAD2B
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
DLG4
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21653829
16713569
12435606
|
ACTN2
|
MYH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
SOCS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22973453
31980649
25402006
24658140
|
EGFR
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
23397142
15657067
24189400
|
GATAD2B
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
HDAC5
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11931768
11804585
21081666
11466315
10869435
10220385
|
RBBP7
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
24981860
|
CTNNB1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
HDAC2
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
PNMA5
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
AR
|
KLK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CBL
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
TRAF6
|
UBE2V1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
25402006
24658140
|
CTNNB1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
5216126
12588987
|
CASP9
|
DCC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16537496
11248093
19721007
|
GATAD2B
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
RBBP4
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
TRAF2
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
FARS2
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
EGFR
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
HDAC1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
AR
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
MTA2
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10444591
25123934
12124384
19703393
24981860
26344197
22939629
12354758
11297506
|
MBD3
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
21670149
24981860
22939629
26496610
11102443
17827154
24048479
26344197
21258344
16428440
12354758
28514442
27068747
19041848
10444591
25123934
12124384
23752268
|
MBD3
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25123934
24981860
20388487
26344197
21258344
22939629
12354758
23752268
17827154
26949739
19041848
|
ADIPOQ
|
ADIPOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
26578976
12878598
12802337
|
ADIPOQ
|
ADIPOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
26578976
12878598
12802337
|
TRAF6
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
34938598
19713527
|
PRKCZ
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18353613
9512493
|
AKT2
|
HSPB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19593530
|
APPL1
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
AR
|
PIK3R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22740037
12063252
20610535
|
RELA
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16713569
8798655
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23158001
24797263
25872741
31182136
10635327
26055326
14505571
15210722
32714745
23774213
19155296
11370743
19836242
8665853
19947936
18271526
25140053
15668240
22394513
17486068
33323455
32377695
22203672
17182860
12604776
14627991
15383614
23153581
15735736
28541302
16849543
17242169
20562913
32904620
9121472
15677445
7782294
16923119
17995934
19531499
15465819
31959764
32114396
23457600
29629558
18316398
23799367
24714105
31120930
12061819
16713569
7657591
33617900
10086340
19225046
33762435
23175185
16729043
28791635
16246327
28198003
15962011
22266821
15117950
27059931
10428778
12734385
8662998
25005938
27903975
16969069
26177020
8798643
10799548
9756944
15159412
19578043
15657067
18255265
23418353
25754235
22976291
17545148
12803489
18319245
19713535
7592693
30544639
15107835
11994282
17971399
16105874
15282549
20940296
23897813
9130710
18273061
18508924
17880946
20124286
12593795
16914641
20877636
10092522
25521828
11408594
22591401
9890970
20308550
22833562
21772844
33627783
11239464
|
CBL
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11053437
12593796
12815057
|
CBL
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18632619
17635922
10514377
|
CBLB
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11087752
17635922
10514377
|
TP53
|
DCC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15843459
|
DLG4
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12713445
16713569
10827173
|
EEA1
|
RAB5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25266290
12493736
25114243
34079125
|
ID1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14688027
16525633
15599381
|
RELA
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17881446
23379415
|
MTA2
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10444591
20714342
19703393
18451879
12920132
26344197
21258344
31980649
24981860
22939629
12493763
11102443
19686092
23752268
11297506
30737378
26949739
|
MTA2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11099047
|
PIK3R2
|
PDGFRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
TGFBR1
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9435577
|
TP53
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17409411
18431400
|
UBE2N
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18981220
14713952
|
APPL1
|
FARS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
GATAD2B
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
UBE2N
|
UBA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
27173435
14517261
29537486
18678647
30097011
27182664
25527291
33619271
31638574
|
MBD3
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
MBD3
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
HDAC3
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
HDAC1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
TUBA1B
|
TUBB2A
|
â—¼ CORRELATES
|
|
+
|
0.92
|
0.92
|
CCLE
|
31978347
|
TUBB2A
|
TUBB3
|
â—¼ CORRELATES
|
|
+
|
0.93
|
0.93
|
CCLE
|
31978347
|
PIK3R1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5217342
15556646
|
MTA2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
6613464
18451879
|
UBE2N
|
UBE2V1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
TUBA1B
|
TUBB3
|
â—¼ CORRELATES
|
|
+
|
0.94
|
0.94
|
CCLE
|
31978347
|
MBD3
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
CBLB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
HDAC1
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
RAB5C
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
17353931
26496610
28514442
34079125
|
TUBA1B
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
MTA2
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
HDAC2
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
HDAC2
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
RBBP4
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
21670149
24981860
22939629
26496610
34518534
11302704
11102443
27705803
17827154
10734134
10220385
9885572
10471499
26344197
21258344
12091390
9150133
16713569
11602581
12920132
20127688
9790534
17643391
11470869
19686092
12943729
9150135
28514442
16189514
27068747
10444591
19703393
11171972
15451426
23752268
20585571
9520398
11118440
31435636
|
RBBP7
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
17255935
22939629
26496610
11102443
27705803
9885572
10471499
26344197
21258344
12920132
9790534
19686092
9150135
28514442
25885317
10444591
19703393
15451426
26186194
23752268
|
HDAC2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
21670149
24981860
22939629
26496610
11102443
11919195
11777905
30737378
9885572
22416134
26344197
21258344
9804427
12493763
11287668
16713569
11466315
12920132
20388487
9790534
10581039
11739383
15987735
17894944
19182791
9150135
28514442
26949739
19041848
10444591
19703393
11804585
25241761
17956988
11564889
12032298
15451426
15297431
23752268
18059533
9520398
|
PIK3R1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20018188
7383613
|
HDAC1
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
HDAC2
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
APPL1
|
APPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
EEA1
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
HDAC1
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
HDAC2
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
TUBA1B
|
TUBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
PIK3CA
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
TRAF6
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CTTNBP2
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
MTA2
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
HDAC1
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CBL
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PIK3CA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ADIPOQ
|
ADIPOR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12802330
21284979
12802337
16622416
|
ADIPOQ
|
ADIPOR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21284979
12802337
16622416
|
ADIPOR1
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16622416
23762377
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
RELA
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20186924
18031796
20649564
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
PRKCZ
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
11585925
15884057
14560023
16189514
11748077
18353613
11723139
10085094
|
PIK3R1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10527852
16799564
19442713
|
PIK3CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25793261
19117013
21041639
24950409
21816939
|
AKT1
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25241761
10490823
25814554
12621049
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20398329
18372248
15004527
15808505
20138985
20214616
15703181
17570479
28177918
18840507
15169778
11714830
10949026
16341064
11715018
18636226
10529400
9812896
17680028
19440551
10722653
20832730
18570873
17052453
|
AKT1
|
HSPB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12740362
11042204
19593530
22983196
17510053
23397142
|
AKT1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
20858269
23331499
20028971
11882383
21303971
17680028
20214616
22094462
17287208
17374729
20398329
21506126
21402455
12040186
19623618
12063252
18218901
|
AKT2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9812896
15004527
|
AKT2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
17287208
20398329
21506126
20028971
12040186
18218901
|
RELA
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24466341
16619263
14576180
15517885
14715080
|
TP53
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17202838
18084622
18945670
11504717
|
AR
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18535113
18673534
20610535
11916967
|
AR
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
17433535
8626436
11059779
15640443
7686046
11006269
12111703
15368351
24307657
9316650
9719026
11867260
12376473
14767470
16275987
11994312
17075604
20181722
9211894
16342680
12917209
18092350
12648523
17011549
11238180
20069563
10547578
16140973
22245379
12539223
20568894
20103546
18758709
21981678
21541973
12463425
12958311
11894840
19389135
17534890
23662037
15923603
16434977
14517289
22695118
10075669
11377978
16137620
11299734
15131260
21780100
16508948
16425097
22473899
14715080
10625666
18640093
21885566
12670590
14729601
16452400
16081584
10898343
11571582
9044850
15833875
16914734
23884959
15640095
15543614
7514587
12376534
12114445
15557561
18780293
23667504
18829551
12782640
16724108
17426252
11504717
19274665
11034093
17566103
12651911
22179832
21308712
16373397
19013180
22155408
9052414
11532861
17094454
17653089
20709811
22654108
22597536
15514031
|
AR
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15305378
19318561
21613411
19258514
15650253
17242169
18692155
15288768
11556855
20610535
|
AR
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19318566
15033751
17202144
19250214
20610535
|
HSPB1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19767773
17974989
|
HDAC1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11994312
16713569
15640443
12612053
10428808
|
AR
|
KLK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1712248
19345326
25241761
|
AR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
21741601
16713569
12799378
12944908
10809237
23331499
15060161
21071413
21885566
18988627
16428447
11916967
12588987
11792709
10987273
14593076
15256534
22187462
|
AR
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18358509
12534934
22260327
15288768
18951974
|
MAP2K2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12792650
18669648
|
PRKCZ
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16287866
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CBL
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9234717
10347229
18988627
17635922
10514377
|
CBL
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
9092574
19190244
11406619
11133830
7629144
17635922
11526404
8662998
8995358
8080844
15107835
23109003
17722974
8621719
16107703
9414268
10514377
15790353
19531499
22315502
19380743
25814554
9461587
|
CBL
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
8641358
9119889
19380743
8621719
7629144
17635922
10514377
|
CBL
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
98.0
|
1.0
|
Omnipath
|
9092574
19190244
16289966
11406619
7642581
11133830
10358153
8941725
9234717
8612729
11157475
10620516
16713569
21203488
11418612
24113870
17635922
18374639
14530346
11526404
8662998
8995358
11030146
9890970
9541596
11042121
15581361
9890943
8080844
7791764
9178909
15107835
8995243
8695807
9988765
23109003
11944898
15556646
17237826
10025673
17722974
8621719
16135792
16107703
16219545
9461587
9160881
9414268
16982329
19861161
10514377
9918857
11087752
9092538
11994282
9259313
15790353
19531499
9174058
8702998
25814554
22315502
19380743
10918571
8896416
|
CBLB
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
19531499
11375397
10086340
12577067
10542134
17635922
10514377
|
CBLB
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11087752
21780115
10488096
19531499
11526404
15032589
23109003
22880054
17635922
10514377
|
CBLB
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
11087752
21780115
10488096
19531499
11526404
10086340
15032589
23109003
22880054
9614102
17635922
10514377
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
FGFR1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17496910
25241761
22558232
11401320
12040186
19568798
14585353
|
EGFR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19104148
27401557
15371335
16099633
22558232
30747223
12040186
26509276
24816560
12740122
25500543
17318191
19568798
21423209
14585353
34227224
23640056
17496910
17052462
24240237
25164010
14517306
21903109
22200182
16952352
20858269
28035485
9233779
|
IGF1R
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17496910
22558232
12040186
19568798
14585353
|
CTNNB1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10477752
25241761
16219695
11716761
|
DNM2
|
OCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
Reactome
|
15260957
10542231
19575674
24966051
10535736
17765681
19536138
21316588
14622578
17158794
21779028
9428629
11082044
22099461
21445324
21613550
14622579
25107275
24581490
|
RAB5A
|
EEA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
15328530
17145710
20534488
14600265
11718716
10491193
11493665
11870209
16902405
15016378
10720461
9697774
|
RAB5C
|
EEA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
25266290
12493736
25114243
|
TP53
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20190820
18359760
9664135
10029407
8152794
11713584
8887630
9285564
19597475
11546792
1586628
18604200
18391986
|
PDCD6IP
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
31980649
15456872
12771190
24658140
15557335
25402006
|
EGFR
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
17496910
31980649
23956138
19531499
16273093
24658140
11172806
1334406
25402006
|
EGFR
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17496910
26918608
7797556
25241761
19531499
16273093
8662998
14967450
16713569
21701776
|
TP53
|
EPHA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11641774
21394211
17050670
23518503
|
EPHA2
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17496910
23331499
7982920
|
FGFR1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17505008
18757403
21666749
11689702
21711248
11739186
21160078
14534538
15448205
|
TP53
|
FGFR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22466965
18811981
16557594
24492005
|
FGFR1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17496910
18412956
25241761
15117958
|
FGFR1
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17496910
15117958
|
FGFR4
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
17505008
18757403
21666749
11689702
11739186
18381441
19809159
21160078
14534538
15448205
|
FGFR4
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17505008
18757403
21666749
11689702
21711248
11739186
21160078
14534538
15448205
|
HDAC1
|
HDAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
15151915
15155580
15465827
16232121
17055429
17508028
17550342
20027199
20713526
20818389
21234400
21733352
2191300
21919891
22370643
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC2
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC3
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
15151915
15155580
15465827
16232121
17055429
17508028
17550342
20027199
20713526
20818389
21234400
21733352
2191300
21919891
22370643
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC2
|
â—¼ UP_REGULATES
|
✅
|
+
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC3
|
â—¼ UP_REGULATES
|
✅
|
+
|
22.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
15151915
15155580
15465827
16232121
17055429
17508028
17550342
20027199
20713526
20818389
21234400
21733352
2191300
21919891
22370643
22796940
23140366
23869868
9618481
|
HDAC3
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11302704
16189514
23213415
10944117
|
HDAC1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564889
11931769
16483679
30670829
16325585
16713569
17183360
21983014
|
HDAC1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
10521394
11099047
22266186
20633551
18765668
20075864
17827154
11313951
14976551
25241761
19303885
12426395
19011633
16697957
16959611
16107876
10777477
|
HDAC3
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC3
|
HDAC2
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC3
|
HDAC2
|
â—¼ UP_REGULATES
|
✅
|
+
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC3
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11533489
16189514
12419806
|
HSPB1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
25241761
16169070
16713569
17184779
|
TP53
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
15131018
11001824
12089352
20633551
24205274
17097318
10023442
17600529
17014845
8710868
12444079
16181796
22033326
|
IGF1R
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8603569
17496910
25241761
8697095
7642582
17570479
18595745
7589433
|
TP53
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15540784
11791186
11504717
|
PDGFRA
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17496910
25241761
8702949
17452978
|
TP53
|
PIK3R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10321740
19763735
21057544
18661553
|
TGFBR1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15657037
9435577
|
STK11
|
PRKAB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
14511394
15579580
8779952
14985505
14614828
11018120
|
STK11
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19197243
15509864
8910387
20160076
|
PRKCZ
|
STK11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11853558
18250273
19414597
16407220
18321849
|
PRKCZ
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11684013
21515635
15210811
21131967
12881425
34230209
16189514
17183360
33864076
27466442
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
RELA
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15041463
19392652
21573233
15723831
9733516
|
STK11
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20815019
11430832
17108107
16713569
|
TGFBR1
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
11013220
11133108
12154066
12717440
12724770
12767520
12809600
14557817
15265520
15548370
16474430
17673906
17934056
18758450
18922473
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
22943793
24132110
24336330
7594497
9865696
|
TGFBR1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
18922473
22710166
23331499
19010789
16474430
22943793
17934056
20519943
12809600
21900405
11133108
18758450
14557817
15548370
19920116
|
UBE2N
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
18710948
1551980
17327397
11057907
15147900
18981220
21113135
17709375
31074699
19549727
18617513
24610907
27791197
29432170
19465916
23885119
15327770
27173435
21872579
25548215
|
UBE2N
|
UBE2V1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
15492226
29662619
10089880
1551980
11057907
16129784
25260751
15147900
22367539
18082144
18678647
26101372
20551964
16307917
17709375
19549727
18029035
21460221
24145445
16215985
20613989
25548215
|