Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AIMP2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 8145365 21285945
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CASP3 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216271 12657644
CASP3 PIP5K1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11042212
YWHAE CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
CBL FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
YWHAZ CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR RAB7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
PML EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12673202 9819401
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
EGFR GRK2 â—¼   COLOCALIZATION 2.0 0.8 intact 5217433 15620700
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
EGFR ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24797263 20029029
GGA3 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
HGS ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS GGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
WASHC3 MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FGFR3 MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214648 11588219
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
PTPN11 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
PTPN11 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
HRAS SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GIT1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ARF6 PIP5K1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12447393 15817676
ARF6 PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12847086
ARF6 PIP5K1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10589680
ARAP1 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
LDLRAP1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NEFL ARFGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ HSPA1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EZR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EEA1 IGF2R â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
IGF2R GGA3 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
IGF2R TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
ARF1 GBF1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8810314 9614177
ARFGEF2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8945478 8945477
ODAD3 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
HRAS CHMP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS CCDC120 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL2RA IL2RB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CDC42 KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
CDC42 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10934474
CBLB ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLB FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
ITCH CBLC â—¼   COLOCALIZATION 2.0 0.8 intact 12226085 5215735
CBLC FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
PRKCI PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213720 11257119
PRKCZ PARD6A â—¼   COLOCALIZATION 2.0 0.8 intact 17057644 5219258
FGFR2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8008273 18332103
ARAP1 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ODAD3 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 CHMP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 CCDC120 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCZ PARD6G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
GRK2 GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18369319 6608764
GRK2 GIT1 â—¼   COLOCALIZATION 2.0 0.8 intact 18369319 6608764
RAB11FIP3 RAB11A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511905 6799554
RAB11A ARF5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17030804 0605357103
RAB11FIP2 RAB11A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
ARFGEF2 ARFGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19332778 0901558106
BIN1 AMPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21779028 11231140
GGA3 TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCDC120 RAB5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRK2 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085131
CAPZB CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAB33B RAB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ CDK18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RAB11B RAB7A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CHMP4A CHMP5 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
PARD6A PARD3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5213720 11257119
DNAJC6 HSPA8 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ARPC1A ACTR2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
AMPH AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR EXOC4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25594178 23956138
ARRB1 HGS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
HGS ARRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
RAB5C ARF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
ARF1 ARF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
DAB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
AMPH AP2S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAB7A CDC42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 31871319
CDC42 RAB1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
FGFR2 FGFR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB1 ITCH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17947233 18544533
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
GGA1 EXOC4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAB5A GGA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 14665628
RAB4A RAB4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
RAB5A GGA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 14665628
EEA1 RAB5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12493736 10491193
CHMP5 CHMP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ASAP3 ASAP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARF6 CYTH3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ARF1 IQSEC1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ARF1 IQSEC2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PIP5K1A PIP5K1C â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
AP1G1 AP2M1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
AP2M1 AP1G2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CASP3 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 9278461 24842904 9840926 21726810
CBL ITCH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
EGFR AP2S1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 25754235 24189400
CXCR2 ARRB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 11170396
IGF2R GGA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5214130 11390366
AP2A2 DAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22323290 11247302
AP2A1 AMPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 12057195 33961781
EPN3 EPN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ARPC4 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
CDC42 CAPZB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
RAB5A RUFY1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 14617813
RAB11B RAB8A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RAB4A RABEP1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EHD2 AP2M1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 15182197
EGFR AP2B1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 24189400 7534311 23956138
EGFR AP2A2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 8548289 24189400 23956138 31959764
ARF6 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11533043 16189514 11867621
AP2A2 BIN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9195986 10430869 9182529
CBLC ITCH â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12226085
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
RAB7A RAB4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 10329441 16962593
RAB5A RAB7A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CHMP2A CHMP5 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CHMP2B CHMP4B â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ARFGAP1 ARF1 â—¼   GTPASE_REACTION ✅ + 0.85 0.85 Signor 10102276
ARF3 GGA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ARRB2 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23208550 18544533
PLD1 ARF6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12379803
ARF6 RAB1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 22939626
PLD2 ARF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12519790 10801846 11373276
AP1G1 ARF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11926829
RAB5C CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RAB7A CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
ITCH BIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26613292 28235806
RAB11A RAB5A â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
RAB5A AP1G1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14665628 31980649
ACAP2 RAB35 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
CDC42 PARD6G â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
AP1G1 AP2M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 10747088 7593184 33961781 26186194
NEDD4 EGFR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR ITSN2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
PLD1 ARF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9688545 26344197
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
PLD2 CAV1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14675200 10675563
PRKCZ PARD6A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5219258 17057644
PARD6A PRKCZ â—¼   COLOCALIZATION ✅ 0.87 0.87 mint 5219258 17057644
CLTC HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AMPH AP2A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARF1 ARFGAP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ARRB1 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AP2B1 ARRB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PARD3 PARD6G â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TNS4 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
AP1G1 RABEP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24797263 20029029 24189400 23956138 25754235 7534311 31959764
IL2RB HGS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21362618 18445679
HGS NEDD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 12230472 23602387 25588945 20675381
PLD1 CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 10747870
ARF6 RAB11FIP3 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
ARF1 ARF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
AP2A2 AP2B1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12086608 16189514 33961781 34079125 26344197
AP2B1 ITSN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 33961781
FGFR2 FGFR3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23972473 33961781
ARRB2 ITCH â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17947233 18544533
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RAB5C RAB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
ARF3 GGA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10749927 11950392 14690499 12221117
ARF5 RAB11FIP3 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RAB7A RAB5C â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
RAB7A RAB5B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10329441 26344197
RAB10 RAB8A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 26344197
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ARF6 GGA3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
RAB11B RAB1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
FAM50B ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
LENG1 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ARF1 GGA3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CHMP2A CHMP2B â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RAB11A RAB11FIP5 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 20029029 31980649 24189400 23956138 24067654 25754235 31959764
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 ITSN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
CBLB EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 11375397 20308550 19531499 33848699 10635327 30515972 18271526 28572092 10086340 16729043 31959764 16702950 15657067
EGFR ARF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 24797263 20029029 31980649
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
EGFR ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
ARF6 ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11533043 16189514 11867621
AMPH AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10748223 33961781
AP2S1 AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12086608 16189514 33961781 34079125 26344197
RAB1A RAB8A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26824392
RAB11A RAB1A â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CHMP1B CHMP3 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RAB11A RAB7A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
AMPH DNM1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
DNAJC6 HSPA8 â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 24789820
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
CLTC GGA1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
CBLC EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22888118 29945960 10571044 10362357 31959764
EGFR CAV2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 15273741 25402006 16799092
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
MDM2 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22869143 16713569 12915590 23169665 14507915 19150978 20972456 15195100 12759344
MDM2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17984062 15878855 32450252 26545496 12488444 11588219 21988832 21466165 33649538 21389118 18544533 21081496 32828283 12538596
FGFR1 NEDD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19953087 25292214 21765395
ARF6 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30944160 12379803
ARF1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16054594 9688545
CYTH1 ARF6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652308 11050434 1511013
ASAP2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
PRKCI EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18270268
PTP4A3 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18078820
PTP4A3 ARF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 22595524 23691193 24376839
PTP4A3 GGA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 22595524 23691193 24376839
PTP4A3 ARF1 â—¼   SHARES_COMPLEX 3.0 0.9 ACSN 22595524 23691193 24376839
PTP4A3 GGA1 â—¼   SHARES_COMPLEX 3.0 0.9 ACSN 22595524 23691193 24376839
PTP4A3 GGA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22595524 23691193 24376839
PTP4A3 ARF1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22595524 23691193 24376839
CYTH3 ARF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ARF1 CYTH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ARF1 CYTH4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
CYTH1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9756891 9653114 10212218
ARF1 PIP5K1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10589680 10747863
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21118812 17620599 12070169 10097102
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
CAV2 CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12414992 16189514 31980649 9361015 18081315 33961781 24013648 10212252
CCR5 CXCR4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12429730 15660419 18632580
CXCR4 ITCH â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19116316 34927784 24489825 28264927 22275353
GIT2 GIT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12473661 28514442 16628223 33961781
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RABGEF1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11452015 27411398 19759177
ASAP2 ARF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
ARF4 GBF1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17956946 22389062 23567335
EEA1 RAB5A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11493665 16902405 15016378 11870209 10720461 34079125 11718716 9697774 10491193 14600265 20534488 15328530
EEA1 RAB5C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12493736 25266290 34079125 25114243
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
RAB11A RAB11FIP4 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
GGA1 RABEP1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
EPS15L1 ITSN2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
AP1G1 AP2B1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CHMP4B CHMP5 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ARFGAP1 ARFGAP3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ARFGAP1 ARFGAP2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RABGEF1 RAB5A â—¼   PHYSICAL_INTERACTION ✅ + 0.92 0.92 Signor 11452015
RABGEF1 RAB5A â—¼   GTPASE_REACTION ✅ + 0.92 0.92 Signor 27411398
PARD6G PRKCI â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
AP2M1 TGOLN2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RAB1A RAB7A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CHMP1B CHMP5 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
AP2B1 LDLRAP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CHMP1B CHMP4B â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
AP1G1 AP2B1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 34079125 33961781 26344197
RAB7A RAB5A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 34079125 22939629 10329441 26344197
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
AP1G1 IGF2R â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6A PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6B PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6G PRKCZ â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
RUFY1 RAB4A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11172003 20534812 34079125 14617813
ACTR3B ARPC2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CAPZA1 CAPZA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
MDM2 ARRB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15878855 11588219 21466165 21857681 18544533 21081496 29676828 12538596 19879840
GGA1 ARF1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12636914 21198641 11950392 15143060 10747089
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
BIN1 AMPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 9348539 9315708 33961781 31413325
RAB5C RAB5A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17353931 26496610 33961781 34079125
ACTR3B ARPC1A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
CLTC DNAJC6 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ACTR3B ARPC3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ACTR2 ACTR3B â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ACTR3B ARPC4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDC42 PARD6A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
RABEP2 RABGEF1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
ARPC4 ARPC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 23148219 11162547 22863883 33961781 24981860 22939629 26344197
AP2S1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 26344197
PARD3 PARD6A â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
PARD3 PARD6B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CHMP2A CHMP3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
RAB5A RABGEF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CHMP3 CHMP4B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CAPZA2 CAPZB â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PARD6B PRKCI â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
GGA3 RABEP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PARD6A PRKCI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
EEA1 RAB5A â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ACTR3B ARPC1B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ARRB1 CLTC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAB5A RABEP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARPC2 ARPC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 11162547 22863883 33961781 24981860 22939629 26344197
GGA3 ARF1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11950392 28100775 11301005 10747089
CHMP2A CHMP4B â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RAB11A RAB11FIP3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CBLC EGFR â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RAB11A RAB11FIP2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ARPC2 ARPC3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 11805826 23148219 22863883 33961781 24981860 9230079 26186194 22939629 26344197
AP2A2 AMPH â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 9280305 9195986 33961781 8552632 10748223
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CAPZA1 CAPZB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CHMP1B IST1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC42 PARD6B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RABEP1 RABGEF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GGA3 IGF2R â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ACTR2 ARPC1A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GGA1 IGF2R â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PARD3 PRKCI â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
CLTB AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
CBLC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10362357 22888118 17635922 10514377
EGFR EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1382070 31980649 24658140 12560083 9230083 15212693 10377409 15647376
EGFR PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9837959 20647543 20176813
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR ARF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12446727
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
HGS AP1G2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20708039 11333915 16867982 9733768
HGS CHMP2A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20708039 11333915 16867982 9733768
ARRB1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15878855 23331499 21081496 12538596 17303558 11588219 21466165 18544533 21857681 19879840
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
HLA-B PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-E PTPN11 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
HLA-G PTPN11 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
CHMP2A AP1G2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20708039 11333915 16867982 9733768
PTP4A3 EZR â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 18078820 21806020 22137788 23691193 24376839
GRK2 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 17447891 25799996 14504278 15531580 24379416 25231728 31409639 11387207 15676024 14993232 21765462 21979959 25531779 19395553 10970850 10893267 15623525 21903131 19255442 15843435 16648854 33583073 34493594 19913059 18725408 26405038 16144865 21864676 16873375 15197272 24413175 18270268 25301939 11146558 21818323 31936668 17553936 30408026 25375189 20801872 26042733 33836044 27435765 19386264
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC1B ARPC4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ASAP2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10022920 11304556 10749932
ARFGAP1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 1010276 10102276 19020038 16189514 9733781
ARF1 PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10801846 11373276 12519790
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
IL2RB IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8568232 15265897 11886175 15933202 15178252 1545122 8260650 3116143 8006584
AP2A2 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
CDC42 PARD6G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 11260256 14676191
CDC42 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10934474 14676191 10873802 11260256 16189514 12606577
CDC42 PARD6B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 20936779 10934474 14676191 25416956 23439680 11260256 32296183
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
GRK6 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30936203 25355818 20048153 24309376 19116316 28328745 24489825
GRK3 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11668182 16189514
PRKCZ PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24152735 23109003 17353362 12390250
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
YWHAE RAB35 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
RAB8A RAB11A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20308558 22433857 22983554 12221131 23567335 21273506
ARF4 RAB11A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17007872 17628206 17030804 19153612 18685082 22983554 23567335
RAB4A RUFY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20534812 11172003 14617813
AP1G1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
RABEP1 RABGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17450153 26430212 24957337 12505986 9323142 17341663 11452015 10720461
CLTB HSPA8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9100026 6146630 17978091 26042225 20033059
RAB11FIP3 ARF4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17007872 17628206 17030804 19153612 18685082 22983554 23567335
ARF4 GBF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22013193 20357002 17429068 18524849 16030262 16633337
RABEP1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15328530 17145710 10720461 11452015 11718716 8521472 26430212 9524117 15378032 9045618
RAB5A EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15328530 17145710 20534488 14600265 11718716 10491193 11493665 11870209 16902405 15016378 10720461 9697774
RAB5C EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25266290 12493736 25114243
RAB11FIP3 RAB8A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20308558 22433857 22983554 12221131 23567335 21273506
PRKCI PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 14676191 22579248 27554858
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
GRK3 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 25923671 12403770 12065593 10085131 11782464 18753410 21148810
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501