Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CTNNB1 INHA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12861022 12732619
HSPA1B SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
GNAQ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20399743
GSK3B MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12584189
OTULIN DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMURF2 DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 NEB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
SMURF2 PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19379695 9674432
SMURF2 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
SMURF2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16950122
CRK PXN â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15308668 16000375
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
TRAF2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNIP1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
THAP1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
POLI DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL12 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 NKD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16273260 21490931
DVL2 CSNK1E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
GABARAP DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20639871
DVL2 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23151663 19379695
HSPA8 VASP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VASP PFN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ABL1 NOTCH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DDX41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DLGAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27899378
RPL27A ACACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AMOT WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21205866 23431053
APEX2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LRRK2 APEX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
NOTCH1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
ARRB2 NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
ARRB2 DTX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
CTNNB1 BAMBI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14660579 12782598
BEND7 EAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DTX1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK DLGAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRK DDX41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DVL3 CSNK1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL3 CSNK1G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10535959
PTEN CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
CTNNB1 FZD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12095419 15473860
CTNNB1 IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
NKD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21490931
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
SQSTM1 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUL3 TNFAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19782033 25416956
DDX41 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH1 DTX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14567914 15965470
ITCH DTX1 â—¼   COLOCALIZATION 2.0 0.8 intact 17028573 5219205
KLHL12 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL3 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0911325107 20439735
PRICKLE1 DVL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17030191
TP53 EAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
RPL27A EML5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EP300 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15752709 18064385
HTT EXOC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNAQ PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
TP53 HSPA1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA1L MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA4 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA4 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RSPO3 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC HSPA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
TNFAIP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLEC HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
NOTCH1 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8313469 19567869
ITCH SH3GL2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5216835 14684745
PI4K2A ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 23146885 8426259
SH3GL2 ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 5216835 14684745
ITSN1 WASL â—¼   COLOCALIZATION 2.0 0.8 intact 5214632 11584276
LGALS3BP MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
TP53 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10529175 9724739
MAP3K1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 15032589
USP9X MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAE MAP3K1 â—¼   COLOCALIZATION 2.0 0.8 intact 9452471 5221876
NOTCH1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10644343 16847353
NBAS OLFM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
PLK1 NUDC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12852857 12679384
PIK3R4 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
TP53 POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10023689 10913176
TP53 PPP1R13B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15090446 15731768
PPP1R13B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16139958
SMURF1 PRICKLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19379695
PTEN RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10753747
WASL PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
RBX1 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
TP53 REV3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
SQSTM1 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RBX1 UBE2G1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
TP53 HSPA9 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5219502 17184779
RSPO3 LGR4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25504990 24050775 29752411
PTEN PTK2 â—¼   DEPHOSPHORYLATION ✅ - 0.81 0.81 Signor 10400703
YAP1 GSK3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24976009 29789528
DVL2 BEND7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27107012 34299191
ARRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
MYC AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
ARRB1 ITCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18544533 17947233
ARRB2 TAB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25241761 17620599
SNIP1 C1QBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30404004 32877691
MYC CTBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
LRRK2 PLEC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20876399 31046837
USP9X YAP1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TUBB TUBB1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
LRRK2 YWHAE â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ZNRF3 LGR4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24165923 33786993 24639526 22575959 33262293
TRAF2 GSK3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 20562859
RNF43 DVL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25891077 32103169 25825523 32965059
WWTR1 AMOT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 20972459
BEND7 C1QBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ITSN1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28484035 32203420
RAB8A LRRK2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26824392 32017888
HTT SQSTM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
TUBB1 TUBB2A â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
DTX1 NOTCH1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EIF5A PFN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MED4 AMOT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25416956 32296183 25281560
PLK1 DVL3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32707033 25659891
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CSNK2A1 SIRT1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
NEDD4 SMURF2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
LRRK2 DVL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
DVL2 PLK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32707033 25659891 31340145
DOK2 ABL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15831486 12777393 9478921
ARRB2 NEDD4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18544533 23208550
CRK DDX6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19380743 31980649
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
HSPA9 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
NEB TTN â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
TUBA1B TUBB1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MYC ACACA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 29467282 17353931
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
GABARAPL1 SQSTM1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
STX18 NBAS â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24056303 26186194 28514442 19369418
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HSPA9 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NBAS STX18 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IRS1 YWHAE â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PTEN PTK2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMURF1 SMURF2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
DVL2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11742073 16189514 16713569
ARRB2 ITCH â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18544533 17947233
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
DVL3 FOXK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
DVL3 FOXK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
MYC ZBTB17 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AMOT YAP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CUL3 KLHL12 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA5 SQSTM1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SH3GL2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAF1 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC GSK3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16247449 20713710 19131971 21150319 31638140 29467282 11877389 33541412 14563837 8247524
FOXK1 DVL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 34299191 33961781 31340145
FOXK2 DVL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 34299191 33961781 31340145
MYC FANCI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 29467282 17353931
PLCB1 GNAQ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16754659 11753430 12193606
RAC1 IQGAP1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 18809683
PLK1 NUDC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12852857 16189514
DDX6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
WT1 INHA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23326390 8701090 8544844
GSK3B FZD5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CSNK1D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21316585 23331499 11818547
GSK3B ROR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21078818
GSK3B MACF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21295697
SMURF2 PRICKLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19379695
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
NHLRC1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22223637
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
RBX1 CCDC8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17332328 24793695 24793696
CSNK1D WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24715453
RBX1 CSNK1E â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK1E ROR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18848778 23331499 15375164
CSNK1E WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24715453
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
DVL3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10644691 10806215
DVL3 DAB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12805222 16189514 16713569
DLGAP4 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NOTCH1 DTX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10933396 9881968 15356142
ITCH DTX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17028573
WT1 DVL3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DVL3 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12533515
DVL3 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 20006983 19625296
GABARAP SQSTM1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
MAP2K1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11160134
PLK1 ITSN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ITSN1 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ITSN1 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 17314511 28628118 9315742
WT1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15286719 17634147 20842112
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPL27A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC NOTCH4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NOTCH1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
NEDD4 PTEN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PDE4DIP TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
REV3L POLI â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
YWHAE RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8005785 11697890
TAB1 RBX1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 REV3L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TK1 TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TUBB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TUBB2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTK2 PXN â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 15688067
TUBB1 TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CTNNA3 CTNNB1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
IQGAP1 RAC1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
POLH REV3L â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
TUBA1B TUBB2A â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
PXN PTK2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 25795725
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
PTK2 PXN â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ITCH DTX1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 18628966 17028573
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
MAP2K2 RAF1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
RAF1 MAP2K1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7014125 19197339
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
WASL ITSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11584276 18539136
MAP2K1 RAF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DDX19B NUP214 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL1 RBX1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DVL2 GSK3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
GSK3B DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
MAP2K1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17081983 21105670 16964243 14617795 30711629 18547980 8382613 17188038 17192257 15020233
GSK3B NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16944320 15465828 12123574 11967263 14663202 8524413 21828089 16713569 9832503 15020233
GSK3B NOTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 16944320 15465828 11967263 14663202 8524413 20068231 12794074 21828089 17570479 9832503 15020233 18669648 15302935
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
GSK3B PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 20080742 19797085 16107342 12040186 23379765 16611981 10671551 16039586 17570479 12615961 25763354 19575820 17444818 20537194 26339505 23210979 17052453 18455992 16371461 11274345 12297295
GSK3B SUFU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17444818 27234298 16611981 20537194 10671551 20080742 19797085 16039586 19575820 21317289 12040186 17052453 12615961 18455992 16371461 11274345
GSK3B BICD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17139249
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
DIAPH1 PXN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15866170 16292343 17306570 17575049
CRK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12198159 27686861 12799422 10329689 10592173 10085298 16713569 7525621 8662907 7537852
ABL1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7615549 15817476 11774284 16254239 15107421 12408869 15572663 11695992 15592455 16094384 10823820 20841568 16713569 9603926 7537852
PTK2 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 16298995 26053221 15688067 15572663 15592455 7963537 17389395 25405379 26546726 9658172 15107421 22581436 10823820 16254239 25226367 15817476 10330411 9756887 19543320 9054445 10545505 18707149 29127427 15494312 10764815 7537852 9442086 33823745 12408869 20419088 20655620 22270917 18669648 28373581 10455189 16094384 23936270 19138410 22638989 11337490 11514617 27402964 16713569 7615549 10931187 11774284 26700725 27708220 20068231 20473365 28928239 7561682 34475475 28427224 28068967 8922390 24885567 23209645 27669437 15212693 26711338 9422762 11304546 28214467 26697169 12065577 28415719 10753828 11919182 24364863 9230116 11113628 21741599 10417825 15252114 24642576 22044652 21034468
PXN CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12198159 27686861 12799422 10329689 10592173 10085298 16713569 7525621 8662907 7537852
NOTCH1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11585921 15546612 11461910 18094723
RBX1 CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 SUFU â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16611981 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258
RBX1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 154.0 1.0 Omnipath 17053147 12684064 20638939 11967263 19797085 19258535 26540345 18826954 15071497 15448697 21765416 25730849 10230406 23343194 21169563 22270359 19250909 23732914 11359933 12051714 20006983 15361859 10748083 19352404 22682247 18787170 12504025 18636226 16469695 15459660 20211143 10535940 15001769 26725323 19411070 11861641 26159692 16697054 1570337 19751508 22822056 11348595 7542250 7641885 19849719 16759355 12820959 17452440 19622404 15703371 10648623 19245792 23331499 9694792 19150432 23180781 19597341 16189514 22474075 18988627 22767593 17143292 24949976 10713156 23770852 22405651 19942853 18196958 20399188 16713974 26192618 11027288 17884153 19933270 22730322 21411632 11961546 17936032 19809470 15147722 19270156 19576224 11483504 20976471 12504026 24023259 12840033 15340381 12904573 20558317 11900249 14536078 19686080 12565873 18805092 15489953 19557001 26885856 17652783 12481031 20843316 11955436 21071413 16039586 11956208 20705860 8666229 17928543 10023660 19836308 16940750 12706828 19143635 15688063 10671552 16123592 19366350 19847258 12417738 11245432 20832730 12648680 12609982 19619488 10230407 18931676
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
DVL2 PFN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18798527 19523939 17373907 17021034
DVL2 FZD7 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 CSNK1E â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
DVL2 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK1D DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21316585 22609948 29426949 31579410
PLK1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20823832
CSNK1E DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 32888647 31515488 22609948 16189514 16713569 10517632
ARRB1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11742073 16713569
DVL2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15262978 12533515
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
DVL2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12958364
ABL1 YAP1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 9168117
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12560071 20841568
ABL1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 25361080 19788416 21199784 29449692 18955976 21051857 18280240 21435002 18701449 27807512 20841568 21214929 21945154 29179447 15459660
ABL1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20841568 10866655
ABL1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17389395 19901323 16199863 19664994 20068231 18707149 18452278 20146487 20841568 19415658
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
AMOT YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 32755583 21205866 26269582 21808241
MAP2K1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28169830 11226259
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
IRS1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837978 8810325 8621590
CRK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 7561682 25814554 12370821 20068231 11602246 10085298 12615911 7509446 7529876 17016520 11314030
CSNK1D YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24715453 23431053
CSNK1D TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10606744 16870621 17101137 9349507 25241761 11709713 10930428 10951572 17570479 19345189 11551930 10747897 10734067 10673501 11883897 16713569 18246126
CSNK1D CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10488109 9312064 23331499 11955436 9482734 14966280 10023673 12000790 11818547 12114015
CSNK1E DVL3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
CSNK1E TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10606744 11709713 10951572 10734067 16713569 11551930 10747897 10673501 11883897
CSNK1E YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24715453 23431053
CSNK1E CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 9312064 7641885 15265686 19718039 21602792 14966280 210606194 8655584 19705439 11818547 19029934 20093472 17430994 21606194 17884187 11955436 9482734 14747478 17570479 12176352 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 12000790 12114015 16547521 10488109 19020754 20940130 12417018 21640127 21087212 17127310 21796133 10023673
CSNK1G1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10606744 11709713 10951572 10734067 11551930 10747897 10673501 11883897
CSNK2A1 DVL3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 TNFAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19851886
CSNK2A1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 16107342 33760042 18723495 25823029 21840932 10866658 24766807 16690621 21779440 24706748 19662498 28263967 15987703 11035045 12077256 24047694 11707428 22413754 17444818 26832662 12297295
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CTNNA3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 23136403 23718855 11590244 21598020
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
FLT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 22558232 17851558 12040186 19568798 22126602 14585353
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
FZD5 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
SQSTM1 CUL3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
DAB2 DVL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 20460648 23331499 21071413 21498506 21304492 16713569 19561074 12805222 15518237 19581931 17318175
DTX1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15684388
DTX1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11153911 20208568 23331499 21071413 11226752 11564735 22162134 18988627
DTX1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11564735
NKD1 DVL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23331499 20858476 19956716 15064403 11274398
DVL3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
ROR2 FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12839624
FZD7 RAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 19365405 18719708 11751577 12533515 9716412 11779461 9674432 23109420 15608632
GABARAPL1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17580304 20562859 23022382 21691068 25416956 31053714 16189514 32296183 21617041 19250911
GNAQ PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11753430 1309799 12193606 16754659 8245028 8387502 1322796 1846707
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
IQGAP1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7731720 14970219 18567582 16135787 17563371
IQGAP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 31980649 28007913 8798539 19079338 9199170 8670801 8702968 15695813 15217908 8756646 18809683
PLK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15849359 8349691
ITCH YAP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157
ITCH SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14684745 17038327 26613292
ITCH NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12682059 10940313 23331499 16713569
RSPO3 LGR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25504990 24050775 21909076 29769720 21693646 29405118
LRRK2 RAB8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 30209220 32227113 32017888 26824392 29357897 29308544 29482628
LRRK2 SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 25501810 24778241 22998870
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
RAF1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 143.0 1.0 Omnipath 10757792 18337766 18799465 15342917 23728975 26496610 15866172 17053865 11242034 9351825 9677429 8157000 7992057 11948414 11604401 16129686 10677502 12695496 19197339 7565670 12750173 7936666 1326789 19219045 23331499 18556463 10976102 18988627 15485920 15175348 18691976 16407412 10409742 9311917 17192257 7898932 8621729 23934108 11684694 21336309 7624324 12920017 11948406 15466214 11042690 12907640 9032297 27169363 12876277 8933152 8223433 8248196 8131746 12594221 10969079 10567369 17979178 17724343 24746704 19058874 10958680 8090753 21071413 7731720 7873542 1330321 8503013 16093354 19541618 8394352 15466476 25155755 11136732 9069260 94178255 8607979 10327068 10359597 8039496 20212043
TRAF2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP3K1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8385802 12048245 8131746 17110930 8034665 8019005 10969079 12456688
RAF1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 7565670 12750173 18799465 16364241 11909642 19219045 21988832 23331499 15342917 8933152 9671314 8393135 9808624 8223433 16189514 18988627 18669648 19541618 16293107 10969079 10567369 8157000 11136732 11948414 7898932 9069260 18039929 19369195 8607979 10327068 17116858 24746704 12920017 16129686 19058874 15466214
RAC1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
TRAF2 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10346818 17145710 25241761 16636664 10755617 18635759 25260751
RAC1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7600581 9487126 7992057 7600582 9733714 9305638
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
MYC ZBTB17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17145710 26766587 18923429 29137325 20426839 11283613 17418410 9312026 20697356 19786833 16352593
NEDD4 PTEN â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17218260 17218261 17996703 18562292 19652529 22679284
NEDD4 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17218261 23331499 21071413 18307411 17218260 18562292 18498243 19345329 19652529 30594392
NOTCH1 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11585921 15546612 11461910 18094723
PLK1 NUDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12852857 27074040 16189514 16860740
SMURF1 PARD6A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14657501 14722617 14744429 15265520 15761148 16472676 21572392 22949611
PARD6A SMURF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21262463 15761148 19114990
RAC1 PIP5K1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16212495 12480336 11152757 10679324 14681219
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
TP53 PPP1R13B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11684014 18676979 14729977 18275817
PRICKLE1 SMURF1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 7641885 8655584
ROR2 PRICKLE1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11226259 12839624 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 16604063 17030191 17127310 17244647 17430994 17884187 18497258 18606138 18851840 19020754 19379695 19565474 19853559 20006983 20093472 20215527 20457807 20579883 20930545 21087212 21316585 21380625 21397842 21572392 21640127 22017973 22949611 7641885 8655584
PRICKLE1 SMURF1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 7641885 8655584
ROR2 PRICKLE1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11226259 12839624 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 16604063 17030191 17127310 17244647 17430994 17884187 18497258 18606138 18851840 19020754 19379695 19565474 19853559 20006983 20093472 20215527 20457807 20579883 20930545 21087212 21316585 21380625 21397842 21572392 21640127 22017973 22949611 7641885 8655584
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
PTEN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9616126 15717329 10427092 23109003 10400703 10592173 9927060 23397142 11857088
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
RAC1 RSPO3 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 ROR2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 ROR2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 RSPO3 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAF1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19608861 16093354 16041367 11697890 8702721 16189514 25852190 7644510 15459208 17979178
RBX1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
SQSTM1 RBX1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
RBX1 SUFU â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16611981 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258
REST TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22684772 15654842 22159867
TP53 RNF123 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10562557 21422812 22085928 11593391
ROR2 SMURF1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 7641885 8655584
ROR2 TAB1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 RSPO3 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 RSPO3 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 SMURF1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 7641885 8655584
ROR2 TAB1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 RSPO3 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 TAB1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 TAB1 â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
TRAF2 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14743216
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
TP53 NOTCH2 â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368