Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TRAF2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FZD7 CLPTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FZD7 PSME3IP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FZD7 ADCY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
GNAI3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8327893 19703466
UBQLN4 AGR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
AGR2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FZD7 AIG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FZD7 CLN8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CTNNB1 FZD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12095419 15473860
CYBA NOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
CYBA NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
RAC1 CYBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10486263
FFAR2 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12711604 31160049
FFAR2 GNAO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12711604 31160049
UBQLN1 FZD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBQLN4 FZD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FZD7 GNAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FZD7 SLC35B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FZD7 PDAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FZD7 WNT5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20457807 24865425
FZD7 PRNP â—¼   PROXIMITY 2.0 0.8 intact 28298427 20167430
WNT8A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10097073
NOXO1 NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
NOXA1 NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
TRAF2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WNT7A UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
NOXA1 NOXO1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17126813 23957209 12716910
COL4A1 COL4A2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DVL1 DVL2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
FZD7 SGTB â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
S39A4 FZD7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AT2B2 FZD7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 WNT5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 WNT11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT7A WNT7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT5A WNT5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LAMP1 FZD7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT7A WNT5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SGTA SGTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
RNF43 DVL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25891077 32103169 25825523 32965059
WNT3A TRAF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT3A WNT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT4 WNT7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DLG4 FZD7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12067714
NOXA1 RAC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20110267 12716910
WNT4 WNT5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RAC1 MGST1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31536960 31980649
PKN1 TRAF2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14741690 32296183
AGR2 SGTB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
SGTA UBQLN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
WNT3A ZNRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23847203 20495530 22575959
COL4A1 ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7542940
DVL2 CCDC88C â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14750955 21031079 22643886
RYK DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15454084 23331499
WNT3A RNF43 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23847203 20495530 22575959
DVL3 CCDC88C â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14750955 21031079 22643886
CCDC88C MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DVL3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10644691 10806215
RAC1 DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
FZD7 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14636582 22179044 19388021
RYK DVL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15454084 23331499
DVL3 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12533515
MYCN FZD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
WNT7A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19497282 22944199 23290138
NOXO1 NOXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12716910 20943948 20110267
SFRP2 WNT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10654605
FZD7 SGTA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FZD7 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
COL4A1 COL4A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
AGR2 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
DVL1 DVL3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 32296183 10330181
CD40 TRAF2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RSPO2 ZNRF3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DVL2 NOXO1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 NOXA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 WNT11 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 FZD7 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 WNT8A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 WNT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 CYBA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 WNT3A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 NOX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 WNT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15262978 12533515
DVL1 WNT3A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
RYK WNT3A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
WNT3A DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
WNT3A SFRP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12775774 17462603 10347172 18322270 16172602
WNT3A SFRP2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12775774 17462603 10347172 18322270 16172602
WNT3A CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 21108734 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 24535659 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
WNT3A RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15454084 23331499 18988627
WNT3A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18215320
DVL3 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GNAS ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9228084 6935665 210183 17652154 2022671 21406690 32196115
CCDC88C DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14750955
CD40 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 20614026 21041727 9133417 25416956 12637493 10352240 16713569 16260598 15485859 25502805 12220533 18635759 25910212 9990007 17353931 8855313 10428814 21282461 10411888 17332487 32296183 16282325 20676093 19667091 9168896 27716849 20449947 9718306 31515488 10318845 21071692 11562359 9020361
WNT2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
DVL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 25241761 10806215 20006983 15735151
WNT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21108734 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 16554443 18936100 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 15208637 21796133
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
FZD7 CYBA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
CYBA WNT5A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
CYBA RAC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
DVL1 WNT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 WNT8A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GNAO1 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19705439 19561403
RYK DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15454084 23331499
DVL1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 15608632 19365405 12533515 17363564
WNT1 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL3 WNT8A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
FZD7 NOXA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
FZD7 RAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 19365405 18719708 11751577 12533515 9716412 11779461 9674432 23109420 15608632
FZD7 NOX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
FZD7 WNT11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
FZD7 WNT1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
FZD7 NOXO1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
WNT5A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10990458
WNT3 FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25892522 18313787 24032637
WNT2 FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23815780
WNT11 FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10862746
RAC1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17251915 12213839 18423204 18426980 10592173 22252525 10930450
NOXA1 NOX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20943948 16329988 20110267
RAC1 NOX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
WNT5A NOX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
WNT5A NOXA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
RAC1 NOXA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
WNT5A NOXO1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
RAC1 NOXO1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
SGTA PRNP â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 23533635 28104892 23129660 23246001 25179605
WNT5A RAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 19365405 18719708 11751577 12533515 9716412 11779461 9674432 23109420 15608632
RAC1 ROR2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 ROR2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
WNT5A ROR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22343533 26690702 23331499 21481194 23151663 18287027
WNT5A ROR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12839624 21316585 16602827 19530173 18215320
ROR2 WNT3 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005
ROR2 WNT3 â—¼   SHARES_COMPLEX 13.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005
WNT5A ROR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 26690702 23331499 12839624 21069266 17203201 20215527 18606138
WNT1 RYK â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
RYK WNT3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
RYK WNT5A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20004982 22773843 16971168 16116452 16280981 23144463 16723543
WNT3 RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15454084
WNT5A RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15598975 22773843
WNT1 RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15454084 23331499 1545408415454080
SFRP1 WNT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18988627 23331499 11287180
SFRP1 WNT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 21071413 10523516 10347172 18988627
SFRP1 WNT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10347172
SFRP2 WNT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9853965
TNFAIP3 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20448643 25416956 24008839 8692885 31515488 32296183 10544141 16713569 10755617