Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JUN DKK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23752183 11867524
FRZB WNT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9326585 21494614
GLI1 FRZB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16328026 17035233
WNT5A FZD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19910923 19582886
WNT11 FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273260 15578921
SFRP2 FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28840375
FZD7 WNT5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20457807 24865425
WNT11 WIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8389626 22986341
WNT16 COT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 WNT5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 TOR3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 WNT11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 PCBP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRP6 FZD8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15908424 11448771 11029007
DKK1 WNT16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17804805 11448771 22807036
DKK4 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 29925589
FZD5 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12857724 18077588
GLI1 SFRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16328026 17035233 19930158
SOST LRP6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21944579 15908424 28514442 21471202
DKK1 LRP6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
LRP6 SOST â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
DKK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 23331499 19339249 21071413 12527209 21944579 11448771 21984209 11357136 11516963 18988627 29925589
WNT11 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
LRP6 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT5A FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10557084
LRP6 FZD2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT5A FZD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 2808370 9389482 19008118 24032637 19910923
SFRP1 FZD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 6172602
WNT5A FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16273260 21903638 15578921 17804197 24032637
WNT5A FZD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10990458 16602827
WNT5A FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 11029007 9054360
WNT5A FZD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16273260 21665003
SFRP1 FZD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10347172
FZD7 WNT11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
WNT5A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10990458
WNT11 FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10862746
WNT5A FZD8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20093360 21518267
FZD8 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11448771 21078818 11029007 20093360
JUN GLI1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26587781 8545107
JUN GLI1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26587781 8545107
JUN GLI1 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26587781 8545107
GLI1 SFRP1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
GLI3 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12435627 14723851 10075717 16571352 19667090
GLI2 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16571352 15175043 12165851 9636069
GLI2 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 20581804 11493558 15140221 16054035 20143239
GLI3 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
GLI3 WNT11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
WNT5A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28143772 19056682 15578921 23462101 18606138
SOST LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22696217 15778503 21944579 15908424
RSPO1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17804805 17976036 18400942