Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
DVL2 YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DVL2 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11779461 18162551
GNB3 GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
WNT5B FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273260 15578921
NLK CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556497
FZD3 CXCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17251915 14977528
FZD3 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22944199 19388021
SCRIB FZD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21983142 16687519
FZD3 VANGL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21983142 16687519
WNT11 FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273260 15578921
WNT4 FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 14671310
WNT5A NLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 20706670
DVL1 DVL2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
GPR21 FZD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GP114 FZD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 WNT5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT16 WNT11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT7A WNT7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT5A WNT5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZBBX FZD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VNN2 FZD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT7A WNT5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RNF43 DVL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25891077 32103169 25825523 32965059
WNT3A WNT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT4 WNT7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SYNE4 FZD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT4 WNT5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT3A ZNRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23847203 20495530 22575959
RYK DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15454084 23331499
WNT3A RNF43 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23847203 20495530 22575959
WNT3A FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21078818 18212053 10601008
DVL3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10644691 10806215
RYK DVL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15454084 23331499
GNB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15782186 16189514 26186194
SFRP2 WNT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10654605
GNB3 GNGT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
DVL1 DVL3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 32296183 10330181
GNAS GNG2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
GNAS GNB1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GNB3 GNG2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNGT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNG2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DVL2 WNT11 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 WNT8A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 WNT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 WNT3A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 WNT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GNB1 GNG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
GNG2 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
DVL1 WNT3A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
RYK WNT3A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
WNT3A DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
WNT3A SFRP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12775774 17462603 10347172 18322270 16172602
WNT3A SFRP2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12775774 17462603 10347172 18322270 16172602
WNT3A CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 21108734 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 24535659 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
WNT3A RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15454084 23331499 18988627
DVL3 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
CSNK1A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 64.0 1.0 Omnipath 9312064 29495399 14966280 23531534 21764279 26227550 29793495 28220106 20561505 26862734 19293931 19623618 27558955 28430641 11818547 25546293 16199882 24648413 28337019 27672271 11955436 9482734 25915038 20419129 23778311 19244247 25500543 27768599 27488834 28183999 17208333 24594309 24038789 23076981 24904820 23690993 23744610 12000790 23687614 12114015 10488109 26604501 19711366 20699366 25517963 26189775 10023673 22025562
WNT2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
DVL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 25241761 10806215 20006983 15735151
WNT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21108734 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 16554443 18936100 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 15208637 21796133
DVL1 WNT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 WNT8A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GNAO1 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19705439 19561403
RYK DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15454084 23331499
WNT1 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL3 WNT8A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
WNT2 FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19038973 24032637
WNT1 FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14642436 15578921
WNT5A FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16273260 21903638 15578921 17804197 24032637
GNGT1 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25675501 8636150 9789084 10360181 12782285 19168127
ROR2 RHOA â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 RHOA â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
WNT5A ROR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22343533 26690702 23331499 21481194 23151663 18287027
WNT5A ROR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12839624 21316585 16602827 19530173 18215320
ROR2 WNT3 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005
ROR2 VANGL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12839624 21316585 16602827 19530173 18215320
ROR2 WNT3 â—¼   SHARES_COMPLEX 13.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005
WNT5A ROR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 26690702 23331499 12839624 21069266 17203201 20215527 18606138
WNT1 RYK â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
RYK WNT3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
RYK WNT5A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20004982 22773843 16971168 16116452 16280981 23144463 16723543
RYK VANGL2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20004982 22773843 16971168 16116452 16280981 23144463 16723543
WNT3 RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15454084
WNT5A RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15598975 22773843
WNT1 RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15454084 23331499 1545408415454080
SCRIB VANGL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21983142 12724779 23140627 16687519
SFRP1 WNT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18988627 23331499 11287180
SFRP1 WNT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 21071413 10523516 10347172 18988627
SFRP1 WNT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10347172
SFRP2 WNT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9853965
WNT5A VANGL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12839624 21316585 16602827 19530173 18215320