Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RECQL4 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
TP53 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15674334
ERG WNT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23913826
PORCN WNT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20826466 10866835
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
TP53 DKK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15229249 10777218
TP53 DKK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
GLI1 FRZB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16328026 17035233
SFRP2 FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28840375
RECQL4 WNT3 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
WNT3A WNT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LRP6 WNT3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
FZD8 WNT3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
LRP6 FZD8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15908424 11448771 11029007
XPC WNT3 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TAB1 TAB2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
WNT3A FZD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21078818 18212053 10601008
DKK1 WNT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17804805 11448771 22807036
DKK4 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 29925589
FZD5 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12857724 18077588
GLI1 SFRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16328026 17035233 19930158
SOST LRP6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21944579 15908424 28514442 21471202
DKK1 LRP6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
LRP6 SOST â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RYK WNT3A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
WNT3A WIF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 19755491 19307728 10201374 15256437 19174556 21743455 22951645 22986341 16427602
WNT3A SFRP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12775774 17462603 10347172 18322270 16172602
WNT3A SFRP2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12775774 17462603 10347172 18322270 16172602
WNT3A FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
DKK1 WNT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17804805 11448771 19339249 22807036
WNT3A RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15454084 23331499 18988627
WNT3A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23400998 21078818 19339249 12897152 14739301 24265322 16890161 22726442 19910923 15578921 20093360 22491013 18772438 21944579
WNT3A FZD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18215320 19910923
WNT3A FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21078818 10557084 11029007 10601008
WNT3A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18215320
WNT3A FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17117926 22753465 24032637
WNT3A FZD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21128903 21665003
WNT3A FZD8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22653731 20093360 22303445
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
DKK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 23331499 19339249 21071413 12527209 21944579 11448771 21984209 11357136 11516963 18988627 29925589
LRP6 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT3 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10557084
LRP6 FZD2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
ROR2 FZD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12839624
SFRP1 FZD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 6172602
ROR2 FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12839624
SFRP1 FZD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10347172
WNT3 FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25892522 18313787 24032637
WNT3 FZD8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18528331 15454084
RYK FZD8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15454084 17035295
FZD8 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11448771 21078818 11029007 20093360
GLI1 SFRP1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
GLI3 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12435627 14723851 10075717 16571352 19667090
GLI2 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16571352 15175043 12165851 9636069
GLI2 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 20581804 11493558 15140221 16054035 20143239
GLI3 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
WNT3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18528331 15578921
SOST LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22696217 15778503 21944579 15908424
RSPO1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17804805 17976036 18400942
ROR2 TAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 WNT3 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005
ROR2 TAB1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 RSPO3 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 TAB2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 RSPO3 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 TAB1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 WNT3 â—¼   SHARES_COMPLEX 13.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 23070005
ROR2 RSPO3 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 TAB1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 TAB1 â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
RYK WNT3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20004982 15454084 22773843 21875946 16971168 16116452 16280981 19000841 16723543
WNT3 RYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15454084
TAB2 TAB1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TAB1 WNT3 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TAB2 TAB1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TAB1 WNT3 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TAB1 WNT3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TAB2 WNT3 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TAB2 WNT3 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TAB2 WNT3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
RECQL4 SFRP2 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
DDB2 WNT3 â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
TP53 WNT3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
POLB WNT3 â—¼   KO_UP_REGULATES ✅ + 1.32 1.32 PKG 28854368
TP53 SFRP2 â—¼   KO_UP_REGULATES ✅ + 1.63 1.63 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368