DVL2
|
YES1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
DVL2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11779461
18162551
|
DVL1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
ZNRF4
|
FZD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RAC1
|
RAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RAC2
|
RAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
TMPSC
|
FZD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
WNT16
|
WNT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
WNT16
|
WNT11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
WNT7A
|
WNT7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
WNT5A
|
WNT5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RHOB
|
BASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
VNN2
|
FZD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RHOB
|
ROR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
WNT7A
|
WNT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RNF43
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25891077
32103169
25825523
32965059
|
GBRE
|
FZD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
WNT3A
|
WNT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
WNT4
|
WNT7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
SYNE4
|
FZD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
RHOC
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
31871319
31980649
|
WNT4
|
WNT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CREB1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
WNT3A
|
ZNRF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23847203
20495530
22575959
|
DVL2
|
CCDC88C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14750955
21031079
22643886
|
RYK
|
DVL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15454084
23331499
|
WNT3A
|
RNF43
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23847203
20495530
22575959
|
DVL3
|
CCDC88C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14750955
21031079
22643886
|
RYK
|
DVL3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15454084
23331499
|
DVL3
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
12533515
|
GNB1
|
GNAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15782186
16189514
26186194
|
SFRP2
|
WNT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10654605
|
DVL1
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
32296183
10330181
|
GNAS
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
GNAS
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
GNB1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
DVL2
|
WNT11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23821037
15936275
10698942
9716412
17130287
9674432
17627283
11358862
11101902
12015986
14636582
|
DVL2
|
WNT8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL2
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL2
|
WNT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23821037
15936275
10698942
9716412
17130287
9674432
17627283
11358862
11101902
12015986
14636582
|
DVL2
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL2
|
WNT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
15262978
12533515
|
GNB1
|
GNG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
GNG2
|
GNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
DVL1
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
RYK
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
20004982
15454084
22773843
21875946
16971168
16116452
16280981
19000841
16723543
|
WNT3A
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
WNT3A
|
SFRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
12775774
17462603
10347172
18322270
16172602
|
WNT3A
|
SFRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
12775774
17462603
10347172
18322270
16172602
|
WNT3A
|
RYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15454084
23331499
18988627
|
WNT3A
|
FZD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21128903
21665003
|
DVL3
|
WNT8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL1
|
WNT8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
CCDC88C
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14750955
|
CSNK1A1
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17209043
9931297
|
CSNK1A1
|
RHOB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
27503856
18590726
|
DVL1
|
WNT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL1
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
GNAO1
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19705439
19561403
|
RYK
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15454084
23331499
|
DVL1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
15608632
19365405
12533515
17363564
|
WNT1
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL3
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
WNT5A
|
FZD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16273260
21665003
|
SFRP1
|
FZD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10347172
|
WNT4
|
FZD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10557084
15265686
21541287
|
WNT5A
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
19365405
18719708
11751577
12533515
9716412
11779461
9674432
23109420
15608632
|
RAC1
|
ROR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11226259
11274345
11756498
12533515
14704854
14747478
15265686
15618519
17127310
17884187
18000759
18497258
18851840
18953287
19020754
19151919
19565474
19853559
20006983
20093472
20215527
21087212
21380625
21796133
22017973
27331412
7641885
8655584
|
RAC1
|
ROR2
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11226259
11274345
11756498
12533515
14704854
14747478
15265686
15618519
17127310
17884187
18000759
18497258
18851840
18953287
19020754
19151919
19565474
19853559
20006983
20093472
20215527
21087212
21380625
21796133
22017973
27331412
7641885
8655584
|
ROR2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
11226259
11698448
11729192
11739775
11779461
11992112
12194823
12361600
12740575
14657501
14704854
14744429
14747478
15265686
15279786
15618519
15761148
16713974
17127310
17303408
17517963
17660363
17884187
18037882
18256687
18423981
18497258
18590585
18851840
19020754
19366350
19565474
19836308
19853559
20006983
20535745
21178402
22017973
22949611
23732914
24857661
24919149
26885855
26885856
27048821
27066895
7479854
7575488
7641885
8655584
9362522
9660866
9822605
|
ROR2
|
RHOA
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
11226259
11698448
11729192
11739775
11779461
11992112
12194823
12361600
12740575
14657501
14704854
14744429
14747478
15265686
15279786
15618519
15761148
16713974
17127310
17303408
17517963
17660363
17884187
18037882
18256687
18423981
18497258
18590585
18851840
19020754
19366350
19565474
19836308
19853559
20006983
20535745
21178402
22017973
22949611
23732914
24857661
24919149
26885855
26885856
27048821
27066895
7479854
7575488
7641885
8655584
9362522
9660866
9822605
|
WNT5A
|
ROR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22343533
26690702
23331499
21481194
23151663
18287027
|
WNT5A
|
ROR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
12839624
21316585
16602827
19530173
18215320
|
ROR2
|
WNT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
10391247
11274345
12620219
14660645
14704854
15082531
17127310
17884187
18264787
18762249
18855897
19020754
23070005
|
ROR2
|
WNT3
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
10391247
11274345
12620219
14660645
14704854
15082531
17127310
17884187
18264787
18762249
18855897
19020754
23070005
|
WNT5A
|
ROR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
26690702
23331499
12839624
21069266
17203201
20215527
18606138
|
WNT1
|
RYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
20004982
15454084
22773843
21875946
16971168
16116452
16280981
19000841
16723543
|
RYK
|
WNT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
20004982
15454084
22773843
21875946
16971168
16116452
16280981
19000841
16723543
|
RYK
|
WNT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20004982
22773843
16971168
16116452
16280981
23144463
16723543
|
WNT3
|
RYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15454084
|
WNT5A
|
RYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15598975
22773843
|
WNT1
|
RYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15454084
23331499
1545408415454080
|
SFRP1
|
WNT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
18988627
23331499
11287180
|
SFRP1
|
WNT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
21071413
10523516
10347172
18988627
|
SFRP1
|
WNT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10347172
|
SFRP2
|
WNT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9853965
|