Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
DVL2 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11779461 18162551
NCF4 CYBA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5223350 17803994
CYBA NOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
CYBA NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
RAC1 CYBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10486263
PRKCD CYBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19948736
ESR1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10935492 12878732
ESR1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18313050 19861308
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
ESR1 PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22430216 18414489
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
PPARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360982 18754816
FOS SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9988737
FOS RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085083 15068801
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
MAPK14 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18253836
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
FZD7 WNT5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20457807 24865425
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
MAPK11 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
PRKCA NCF1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219276 17069809
NCF1 PRKCD â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219276 17069809
RELA NCF1 â—¼   COLOCALIZATION 2.0 0.8 intact 12618429 5216185
RAC1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11893732 9255350
NOXO1 NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
NOXA1 NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
PPARG NOX4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31023188 20622120
RELA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10542237 16189514
PPARG VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18755353 11007963
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
NOXA1 NOXO1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17126813 23957209 12716910
CPT1A RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 22939629
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
VCAM1 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NOXA1 RAC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20110267 12716910
SPI1 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9681824 12091339
NCF2 RAC1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
S100A8 CYBA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
S100A9 CYBA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
CYBA NOX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15824103 17583407 16507994
RFK CYBA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 12440767 17560373 19641494
CYBB S100A8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
CYBB S100A9 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
ESR1 WNT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
JUN VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9468519 16271621
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303700 20352621 17498959
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
S100A8 NCF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
S100A9 NCF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
NCF1 NOX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15824103 17583407 16507994
NCF1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NCF1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
RAC1 NCF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11896062 7738010 9642115 9624165 16189514 25416956 8036496 9255350 11090627 25301945
NCF4 NCF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16297854 11893732 16782902 10672014 11796733 12887891 12813044 9083043 11483497 9490029
S100A9 NCF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
RAC2 NCF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9642115 11090627 9624165 16189514
S100A8 NCF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
NCF2 NOX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15824103 17583407 16507994
PRKCA NCF2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NCF2 PRKCD â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
SPI1 NCF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20025940 10570299
S100A9 NCF4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
PRKCA NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
PRKCD NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
S100A8 NCF4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
NOXA1 NOX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15824103 17583407 16507994
NOXO1 NOXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12716910 20943948 20110267
PRKCA NOXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20110267
RELA PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20054868 10542237
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
S100A8 RAC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
S100A9 RAC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
TNFRSF1A TRADD â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
NCF2 NCF1 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 12169629 5215640
S100A8 S100A9 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
DVL2 NOXO1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 NOXA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 FZD7 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 WNT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 CYBA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
DVL2 NOX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
PRKCA DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
DVL2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15262978 12533515
NOX4 POLDIP2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15927447 16179589 19372727 19644055 19732719 19995913 21273445
CYBA POLDIP2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15927447 16179589 19372727 19644055 19732719 19995913 21273445
CYBA POLDIP2 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 15927447 16179589 19372727 19644055 19732719 19995913 21273445
NOX4 POLDIP2 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 15927447 16179589 19372727 19644055 19732719 19995913 21273445
PPARA CPT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15489052 24146969 17150915 18566121 19710929 11171094 20638986 15356291 20656057 16177188
FZD7 CYBA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
CYBA WNT5A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
CYBA NOX4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15927447 16179589 19372727 19644055 19732719 19995913 21273445
CYBA NCF1 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA CYBB â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA RAC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
CYBA RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
CYBA NCF2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NOX4 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 15927447 16179589 19372727 19644055 19732719 19995913 21273445
CYBA CYBB â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF1 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
CYBB NCF1 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF1 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
SPI1 CYBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11241298 15618156 9593745 11926990 10233904
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
FOS MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16554298 11774399 21238464 18809380 23508111 21474819 15319566 10935492 21940623 24173318 16882662 21047770 9136992 23955082 23176293 12032150
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
FZD7 NOXA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
FZD7 RAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 19365405 18719708 11751577 12533515 9716412 11779461 9674432 23109420 15608632
FZD7 NOX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
FZD7 NOXO1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
WNT5A FZD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10990458
JUN S100A9 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26587781 8545107
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
PPARA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10542237 17360982 18754816 15838301
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19268464 15212943 14767528 19940138 11414701 15777790 20353950 17116726 16000878
JUN SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17283046 10411939 9178763 9988737
JUN MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 16798740 16554298 11774399 15949416 11429784 15777790 16014933 10935492 11326313 18809380 21474819 21963718 19455716 9136992 17572495 23176293 15708369
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
MAPK14 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12475989 17689131 17570479 25483191
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
JUN SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12393465 10411939 12091339
NCF1 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
NCF2 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
NCF4 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
NCF1 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
NCF2 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
NCF4 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
PPARG MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17908458 17625041 16609149 15838654 19345798 17425848
MYC MMP9 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PPARG MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20021931 22472882 22207709 9665460
RELA MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 18298869 12105194 11376631 14600595 17673602 23423566 17922642 15605368 14755547 20332461 18357389 21502320 17186550 11060311 18566231 9679762 16554298 16687076 17121934 15086314 18843978 21963718 18056465 20103608 21238464 17174275 15536164 18028425 17158602 17590163 19303700 7860222 19539355 9500201 22587999 19783786 18567920 15175338 17498959 19616091 10359016 18801463 19454280 24755270 19662350 12193473 16014933
PPARA MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17077283 21840940 19576184
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
NCF1 NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF1 RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
NCF1 NCF2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF1 NCF2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF1 NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
PRKCD NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8626435 17069809 23109003 12734380 96198102 16297854 9857051 11145703 7657821 10336447 12056906 94375440 8089108
PRKCA NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17069809 9857051 11145703 23085266 24632950 17570479 23002436 17217339 23119229 8626435 12734380 96198102 94375440 8089108 24970888 15657040 7520867 31736979 10559253 22460559 12056906
NCF2 NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF2 NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
RAC1 NCF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9624165 11090627 9642115 25416956 16189514 7738010 25301945 11896062 9255350 8036496
NCF2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 9624165 11090627 9642115 25416956 16189514 7738010 25301945 11896062 9255350 8036496
PRKCD NCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15035643 9804763
RAC2 NCF4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
NOXA1 NOX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20943948 16329988 20110267
RAC1 NOX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
WNT5A NOX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
RAC1 NOX3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 15824103 17583407 18347018 16507994
WNT5A NOXA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
RAC1 NOXA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
WNT5A NOXO1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16636067 18347018 11779461 12716910 8947551 16329988 16762923
PRKCA NOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26781991 23322165 23957209
RAC1 NOXO1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
PPARA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10377075 16115476 17434475 11459775 18755353 11007963
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
WNT5A RAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 19365405 18719708 11751577 12533515 9716412 11779461 9674432 23109420 15608632
RELA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10833420 20966071 16317091 7536741 16627481 16385502 10946302 19422386 22708120 23042817 19281832 10553096 10329958 11359843 7692229 16249517 10496926 7537851 16453001
TRADD RFK â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10734135 11274345 12887920 14730360 15310755 17560373 18292600 18641653 19641494 21232017 23010170 8974401
S100A9 S100A8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12645005 18802069 18809714 19732719 23248262
S100A9 S100A8 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12645005 18802069 18809714 19732719 23248262
TRADD TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRADD TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRADD TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 17145710 8565075 8943045 11934887 8612133 9915703 11684708 8621670 9430227 19641494 27552911 16611992 21760970 11821416 10187805 21724995 12721308 21741934 21232017 10795740 21119000 15310755 11502070 15115707 23955153 18776134 18939944 9916731 9129204 9082980 15485837 15173123 22297296 15357952 24130170 12887920 10634209 24758719 19524513 15465831 7758105 11035039 8791485 15725726