UBC
|
ICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17174307
5219467
|
STAT1
|
ICAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19935876
|
TNF
|
ICAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21474822
22846676
|
RIPK1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10880512
5212735
|
UBB
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RNF31
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24469399
21455180
|
TP53
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TP53
|
MAP1B
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
18656471
6700545
|
RBCK1
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18711448
|
UBB
|
DAZAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
UBB
|
OTULIN
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
26235645
7851534
|
RBCK1
|
RNF31
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
OTULIN
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBC
|
OTULIN
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
26235645
7851534
|
OTUD7B
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
SHARPIN
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
23032186
8410237
|
RNF31
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
SHARPIN
|
RBCK1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
23032186
8410237
|
OTULIN
|
SHARPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
TNF
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
23815148
8432069
|
UBB
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
RNF31
|
IKBKG
|
â—¼ POLYUBIQUITINATION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
24469399
|
BCL10
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
IKBKG
|
SHARPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
OTULIN
|
RBCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
RBCK1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
RBCK1
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
IKBKG
|
RBCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
SHARPIN
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
IKBKG
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
STAT1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24655378
14602726
|
MALT1
|
BCL10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21157432
31774199
23690623
25748427
17948050
20551178
17189706
21513986
22658522
22267217
14695475
22528498
27070702
31961340
11262391
24130731
27071417
33329596
19444310
27113748
25548215
11090634
30279415
19279678
25569716
18806265
33961781
29953499
19118383
27777308
|
RNF31
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
IKBKG
|
RNF31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
IKBKG
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
OTULIN
|
SNX27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
UBC
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
IKBKG
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
MALT1
|
BCL10
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
17948050
6177522
|
SHARPIN
|
RNF31
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
23032186
8410237
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
OTUD7B
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
OTULIN
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
RNF31
|
RBCK1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219147
17006537
|
OTULIN
|
RNF31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
RNF31
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
TP53
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
22154326
22178888
23677569
15578696
17363498
24098340
18064040
23527225
10893263
21859835
|
STAT1
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11641425
19122651
9888295
9353323
11278281
12651068
7957928
23347335
10830295
22951020
9990314
|
RNF31
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RIPK1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
RBCK1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
MALT1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
11280761
11356195
11460167
12356734
14660645
16809782
16818229
17052756
17301840
17363905
17462996
17948050
18264101
18264787
20685844
21133840
21199863
21232017
21873235
24560716
24699077
24958845
|
SHARPIN
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
IKBKG
|
BCL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11280761
11356195
11460167
12133805
12356734
14660645
15145317
15199157
15485931
15536066
16809782
16818229
16970925
17052756
17237376
17254973
17301840
17363905
17462996
17485448
17693255
17948050
18264101
18264787
18716620
19302050
20138012
20300203
20685844
21133840
21199863
21217011
21232017
21807870
21873235
22435554
23086447
23422957
23430059
24560716
24699077
24958845
2649237
28462531
|
TNF
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
IKBKG
|
STAT1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
38.0
|
1.0
|
ACSN
|
11280761
11438547
11460167
12133805
12811837
14660645
15145317
15199157
15485931
15536066
15573129
16818229
16970925
17237376
17254973
17301840
17363905
17485448
17693255
18264787
18716620
19833085
20138012
20300203
21133840
21217011
21232017
21807870
22435554
23086447
23422957
23430059
24378531
24699077
24766893
24958845
2649237
28462531
|
RIPK1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10880512
21383699
21458669
14653779
10980203
17702576
9927690
16603398
16547522
16965765
10755617
|
BCL10
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
14695475
19897484
18287044
27070702
17363905
|
RIPK1
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
RIPK1
|
TNF
|
â—¼ SHARES_COMPLEX
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
STAT1
|
TNF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
46.0
|
1.0
|
ACSN
|
10485906
10754326
10820262
10952726
11134049
11399519
11830590
11875494
11964313
12193701
12223527
12433365
12796776
12811837
12907458
12967644
14607900
14607933
14660645
14764699
15465827
15644117
15699106
15814715
16127449
16878026
17016554
17260466
17404308
17485448
17513775
17559085
17689680
18272812
18345002
19833085
19879327
21097505
21263073
21930765
23390297
25960930
6357187
7594497
8683106
8871614
|
TP53
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18172499
18695251
24667498
22056774
17290220
17592138
12421820
18413597
20173098
19556538
21857681
17470788
18359851
19805293
19196987
12640129
|
BCL10
|
MALT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11280761
11356195
11460167
12356734
14660645
16809782
16818229
17052756
17301840
17363905
17462996
17948050
18264101
18264787
20685844
21133840
21199863
21232017
21873235
24560716
24699077
24958845
|
BCL10
|
MALT1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11280761
11356195
11460167
12356734
14660645
16809782
16818229
17052756
17301840
17363905
17462996
17948050
18264101
18264787
20685844
21133840
21199863
21232017
21873235
24560716
24699077
24958845
|
STAT1
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
46.0
|
1.0
|
ACSN
|
10485906
10754326
10820262
10952726
11134049
11399519
11830590
11875494
11964313
12193701
12223527
12433365
12796776
12811837
12907458
12967644
14607900
14607933
14660645
14764699
15465827
15644117
15699106
15814715
16127449
16878026
17016554
17260466
17404308
17485448
17513775
17559085
17689680
18272812
18345002
19833085
19879327
21097505
21263073
21930765
23390297
25960930
6357187
7594497
8683106
8871614
|
RBCK1
|
SHARPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RBCK1
|
SPATA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
26997266
27591049
27545878
24098568
27458237
27307491
22435550
|
RBCK1
|
RNF31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RBCK1
|
RNF31
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RBCK1
|
SHARPIN
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RNF31
|
SHARPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RNF31
|
SHARPIN
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
OTULIN
|
UBC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23708998
23827681
24726327
25527291
23746843
26235645
|