DVL2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7890890
20224554
|
TP53
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
EP300
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23353771
23285190
|
E2F2
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7958836
|
EGFR
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16299810
|
E2F1
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19303924
|
E2F1
|
E2F2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15014447
18319725
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
TP53
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
TCL1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0810965105
19064921
|
TP73
|
EP300
|
â—¼ ACETYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11804596
5215037
|
TP53
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
LZTS2
|
NINL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
LZTS2
|
CCDC85B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
H2BC9
|
MCRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HRAS
|
MCRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MCRS1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TP53
|
MLH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15781865
|
TP53
|
PPP1CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
TP53
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
TP53
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PRKAB2
|
TP53
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PPP1R13B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15090446
15731768
|
TP53
|
E2F3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20428827
|
PPP1R13B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16139958
|
TP53
|
TP53I3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15067011
|
TP53
|
LATS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17015431
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP73
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14729977
5216867
|
TP73
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22842668
21127199
|
KRT20
|
CCDC85B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
DVL2
|
FAM90A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
FAM90A1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
H2BC9
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RAN
|
SMG6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
H2BC9
|
NDC80
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC9
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PSIP1
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPP1R13B
|
CEP104
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
E2F2
|
PPP1R13B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
15731768
|
E2F3
|
PPP1R13B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
15731768
|
HRAS
|
RALBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HOOK2
|
RALBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
DEUP1
|
CCDC85B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
LNX1
|
CCDC85B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CCDC85B
|
HMG20B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CCDC85B
|
ZFP36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HRAS
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
FAM184A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
TEX12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
ERBB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
HRAS
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9069260
21779497
|
HMG20B
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
LNX1
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
TRAF1
|
LNX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
TRAF1
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
LNX1
|
KHDRBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
H2BC9
|
TRAF3IP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CDC5L
|
PPP1CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
MIS18A
|
TXLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
CEP63
|
NDC80
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
32296183
|
CEP63
|
TXLNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25416956
26638075
|
PPP1R13B
|
TEX12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
EGFR
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24797263
15657067
|
NINL
|
LZTS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
16713569
26638075
|
TCL1A
|
TXLNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
25416956
33961781
|
NDC80
|
TXLNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
29892012
25416956
30886144
|
RNF43
|
DVL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32103169
25825523
25891077
32965059
|
PPP1R13B
|
RASSF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
MIS18A
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
E2F1
|
E2F3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
35140242
24981860
20106982
|
EP300
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12649209
33742100
|
ERBB2
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30898150
28628118
28205554
|
LATS2
|
CPVL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
24255178
|
KRT20
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
C2orf42
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
DGCR6L
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
LATS2
|
LATS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
24255178
34079125
32707033
21233212
|
BFSP2
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
PPP1R13B
|
TEKT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
KRT4
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
PPP1R13B
|
TXLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
PPP1R13B
|
RALBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
E2F1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
LZTS2
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
29395067
|
DVL2
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20224554
26496610
|
FAM90A1
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
PPP1CC
|
PPP1R10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
LZTS2
|
PRR35
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
CGN
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
CDC5L
|
TXLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
SIAH2
|
LATS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27030211
25438054
|
LMNB1
|
LMNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
CDC5L
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
LMNB2
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
PPP1R13B
|
PRR35
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
GOLGA1
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
CAPN7
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
NHSL2
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
ACSF3
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
PPP1R13B
|
TCL1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
EP300
|
TP73
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
TCL1A
|
TXLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
KHDRBS1
|
KHDRBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
PPP1CB
|
PPP1R18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
FAM90A1
|
LZTS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
PPP1CA
|
PPP1CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
PPP1CB
|
PPP1CC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
KRT20
|
TXLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
CKS1B
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
NDC80
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
DIRAS1
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
LMNB1
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
PPP1R13B
|
RASSF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EP300
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21102443
19887647
10655477
11782371
16713569
21212407
22787115
|
MLH1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10783165
17148452
25184681
16786532
21240188
29656893
|
E2F2
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17106239
|
E2F3
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17106239
|
E2F1
|
PPP1R13B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21479363
15731768
15706352
|
E2F1
|
FGFR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19303924
|
E2F3
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14576826
10766737
18319725
|
EP300
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10753885
15123636
15126619
|
E2F1
|
PPP1R13B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18319725
15731768
15706352
|
EGFR
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500850
25241761
30898150
17486068
11526509
9461599
23866081
17426253
10572067
11500516
24557338
8665853
15657067
19060928
16516204
19650109
20211985
25315821
23436906
21278786
25898135
32669362
1346931
24189400
21044682
18803307
16843263
28369073
7531698
16713569
17148612
21203579
17307140
1706616
16207817
7797556
12354693
11408594
|
TP73
|
MLH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11309270
18829110
21245298
|
TP53
|
MLH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18431400
15781865
|
TP53
|
HNRNPUL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
HNRNPUL1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15907477
|
E2F3
|
TP73
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15210709
|
LMNB1
|
LMNB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
24981860
33961781
30021884
34079125
26524528
|
PPP1CA
|
PPP1CC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
BRCA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
PPP1CC
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
PPP1CA
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
PPP1CA
|
PPP1R10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ POLYUBIQUITINATION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
12690203
|
APC
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
PPP1R13B
|
PPP1CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
21998301
270751
8217559
|
ERBB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5218411
16516204
|
TP53
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16611888
6599495
|
EGFR
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
TP73
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18034190
17346710
18421303
21245298
10559267
18418051
18644986
17521288
19067706
11748232
|
E2F1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9748148
11095619
12370749
14514686
15255934
|
TP53
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11278953
12203124
16931621
9582019
17693666
11118038
12433990
11395510
8183578
11429705
10400708
15242522
11423991
19067706
24336083
18381427
22732402
15988033
16341121
10935506
10094833
16215989
17280505
10744634
12851404
20673369
15851483
8845569
10559267
12168779
11850816
19505426
8564971
11756653
19054058
15566940
12173040
17690113
8635454
18034190
10510469
10101800
11335718
23100276
9400998
9445173
9582400
24098340
22532570
9122197
11420692
11104574
15679092
11748232
12560513
11928223
20400479
20546728
17145718
20567883
20840522
18172861
10566557
10777477
7834749
12806965
17521288
19242108
9000137
21859835
|
TP53
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14963330
16151013
7834749
|
BRCA1
|
E2F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
E2F1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
E2F1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
E2F1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10660629
23285190
18660752
19466541
17106239
20068145
23108140
|
TP53
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
9582019
11295099
18625847
11003642
12802282
16357511
14710355
9619832
19882681
10884389
11384963
11782367
12024039
15735697
12170778
21245169
17993233
12549011
11431698
16229810
18208621
10597265
21742769
|
E2F1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9244350
18660752
18319725
11278247
12697828
16713569
12909625
|
PPP1CA
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
25056273
12438214
17511879
17603999
|
TP53
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21715977
20805247
8557038
11795482
17210690
22952705
|
E2F3
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14576826
7958836
12063292
|
E2F1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22241525
8557038
15706352
21441950
12675512
23954287
12625370
|
E2F1
|
TP73
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12766778
11101847
11988839
14602923
18660752
19188449
18029729
18521084
15210709
11115495
17980704
19363520
12789260
21310950
22952705
|
E2F1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15210709
11988839
17488475
11937641
|
E2F1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22480684
11739724
12625370
|
TP53
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20190820
18359760
9664135
10029407
8152794
11713584
8887630
9285564
19597475
11546792
1586628
18604200
18391986
|
EGFR
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
17081983
16207817
21044682
17148612
24557338
16713569
21203579
10233167
20471394
17389395
17486068
21278786
11500516
11279155
11500850
17426253
16843263
19650109
25241761
24189400
15657067
17307140
18803307
1706616
12354693
10572067
24355130
11408594
19060928
12648464
16516204
15951569
23436906
20211985
|
EP300
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
137.0
|
1.0
|
Omnipath
|
11907332
25545885
21187340
10706102
16438982
10490106
19339993
15542844
23010591
11433299
19608861
17438265
17906639
16024799
9194564
20234175
23402884
12162806
26229107
16959611
15186775
9744860
11070080
17977830
17189186
22266186
20228809
15664194
19805293
25753752
11804596
26625199
27818144
10648616
16928824
9288740
10942770
12724314
23148227
23728348
15965232
19218448
16678111
16782091
20094059
14612423
24821727
10518217
16713569
9891054
25288747
17452980
14759370
19788416
25156994
18931695
22074660
23880760
15337767
15509808
26302407
22731250
18391200
16543236
19234109
21471221
23307557
25867071
12690203
15558054
18612383
23870121
18243116
19217391
22013068
16537920
16611888
18485870
9194565
12660246
9809062
23796514
11359905
12501250
15295102
19407812
25651062
23329847
16135789
|
EP300
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
11804596
19407812
15175157
19788416
12660246
19218448
10648616
15454570
16998810
25675294
15893728
18663001
|
TP53
|
EPHA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11641774
21394211
17050670
23518503
|
TP53
|
PPP1R13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11684014
18676979
14729977
18275817
|
TP53
|
TP53I3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10321740
10101800
12851404
14695213
15192123
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
FGFR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22466965
18811981
16557594
24492005
|
PPP1CB
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16501611
15178317
|
PPP1CA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
16501611
16713569
15231748
15178317
|
PPP1CC
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
17274640
15178317
16501611
|
TP53
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11238924
18431400
21508668
9891077
|
HRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HRAS
|
FGFR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|