Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TCL1A NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CEP55 NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX2 NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRAF1 NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NTAQ1 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TLE5 TCL1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12421830
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JUN ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
NR4A1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11274386 16835233
TCL1A AKT1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
LNX1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TCL1A CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CALCOCO2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CEP55 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CREB1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
CREB1 TCL1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
DNMT3A POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21608077 22867868
TCL1A EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
TCF4 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219834 17410209
TCL1A FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
TRAF1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HSPA4 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TCL1A JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
TCL1A JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19064921
TCL1A JUNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
TRAF1 LNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX1 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRAF2 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TCL1A LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRAF1 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX2 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX2 TCL1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NIF3L1 PRTFDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NIF3L1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SP1 NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8961265
CCDC13 TCL1A â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
CCDC13 TXLNB â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KLF2 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15136591 21482710
JUNB EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21937452 15308641 17510411
CACO2 CEP55 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NTAQ1 TRAF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT3 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LNX1 LNX2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22889411 11922143
DNM3A TCL1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
TCL1A CACO2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32296183 21516116 25416956 16189514
TRAF2 CACO2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 16713569 33545068
DDIT4L LSM3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
NFKBIA TCL1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
TCL1A TRMT61A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
AKT2 AKT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 11546794 11278835 12149249 14500673 9736715 12176337 28514442 11445557
ATM CREB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15073328 17209043 16293623
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
EP300 KLF5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
PPP1R13B TXLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
AKT1 TCL1A â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TCL1A AKT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11707444 10983986
CALCOCO2 TCL1A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
PPP1R13B TCL1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
ABL1 ATM â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TCL1A TXLNA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
AKT1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 11274386
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EP300 NR4A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12082103 21988832 16713569 20438716
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
TTC33 TXLNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
TXLNA TXLNB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ATM ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20798688 17409407 9168117 9168116 10212258 11375976
TCL1A AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25910212 11707444 26871637 29997244 27229929 25416956 12009899 16189514 10983986
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
AKT2 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284
AKT3 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284
TCL1A NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19668332
TCF4 NR4A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDIT4L TCL1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TCL1A TTC33 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
EP300 TCF3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ATM ABL1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 17303408 22334513 11375976 11804596 23331499 21071413 16163361 17570479 18988627 9168116 23847781 9168117 20798688 15964794 19788416 9561848 22084676 12607003 10212258 15459660 11877377 15686624 17409407
ABL1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19818398 18619508 10637231 20841568 14757045 15302935
ABL1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14757045 20841568 12167702
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
TCL1A AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10983986 25910212 26871637 10716693 25416956 29997244 12009899 19770358 31515488 16189514 11707444 15169787
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25581517 11274386 16223362 17570479 16713569 26155943 18669648
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
TCL1A AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10983986 15169787 11707444
AKT2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17964260 16926151
AKT2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
TCL1A AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10983986 11707444
AKT3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
ATM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16293623 15073328 17525332 15212693 23642045 19115993
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
SP1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17626239 10082538 9528985
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
SP1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7553870 9060426 2674689 24669866
JUN TCF4 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN TCF4 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN TCF4 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN TCF4 â—¼   DOWN_REGULATES ✅ - 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18163434 19751824 16264271 20847229 7969116 8413214 10772826 10567637
JUN TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16007074
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368