Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GSN ELL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ELL2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IKZF3 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TP53 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KRTAP1-3 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRN PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAB2 GET4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PRKAB2 CCDC33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PRKAB2 TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
IHO1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SPRED1 KRTAP10-7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
METTL27 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 TASOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TASOR2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TASOR2 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AGL GYG1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9691087 2961257
DYNLL2 AMBRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20921139
GSN AUNIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11382762 16133124
BECN1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BECN1 VBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BECN1 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TSC1 BEND5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GSN BLZF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C3ORF36 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN C3ORF36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TSC1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TP53RK CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCDC33 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PFDN5 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CALCOCO2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CALM1 CAMKK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10770941 7642608
TP53 CASP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21859926 16177095
TP53 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAG1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RHEB CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MDFI CRX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
DYNLL1 TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
ULK1 DYNLL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20921139
RNF11 ESM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GORASP2 GOLGA2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21900206 2001699 8089645
IKZF3 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TCF19 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TSC1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GOLGA2 IKZF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PLEKHG7 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF15 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP3K5 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRN PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STX19 GSN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL37 GSN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN PLEKHG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN PPP1R16A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN ZNF581 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GYS1 GYG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PYGM GYG1 â—¼   GLYCOSYLATION ✅ 2.0 0.8 Reactome 2667896 10949035
KLF15 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRTAP4-12 ZNF581 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP9-2 TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
TSC1 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ZMYND19 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LZTS2 ZNF581 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNF581 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MEOX2 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MLST8 RHEB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NAB2 ZMYND19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SPRED1 NEBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHKG2 PYGB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9362479 17081983
RNF11 PLEKHG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 PLEKHG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLEKHG7 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PPP1R13B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15090446 15731768
PPP1R13B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16139958
PRKAB1 PRKAA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6767403 18480843
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
RNF11 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PRKAA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAB1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
PRKAB1 ULK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21460634 21072212
TP53 PRKAG1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RBM48 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RB1CC1 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16043512
RBM48 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SPRED1 RHEBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR83 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RRAGD RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20006481 18497260
WDR83 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIB3 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STX19 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 TRIM42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 STX11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 ZNF581 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 TP53RK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11546806 12914926
TSC2 TSC1 â—¼   COLOCALIZATION 2.0 0.8 intact 6547838 9580671
ZNF581 VBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MLST8 RRAGC â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MLST8 RRAGA â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
KRTAP4-2 OXER1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
GOLGA2 GORASP2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CALM1 GSC2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
GSC2 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
GSC2 TSR2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
ULK2 ATG13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18936157 20562859
NAB2 GRN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PYGM PYGB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
PRKAA1 PRKAG1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
GYS1 STBD1 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
KRTAP4-12 SPRY1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
TSC2 MTOR â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 12271141
KRTAP3-3 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
STBD1 GYS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STBD1 EPM2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STBD1 PYGB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TSC1 RHEB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30514904 12820960
CALM1 DDIT4L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRTAP3-3 KRTAP4-2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PIAS2 TP53 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
RHEB TSC1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ATG14 ULK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRTAP9-2 SPRY1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
RPTOR ULK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRTAP9-3 SPRY1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRTAP4-2 KRTAP4-5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRTAP10-5 KRTAP4-2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
ULK1 RPTOR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21795849 25686248 21460634 21460630
MTOR ULK1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 21460634
C2ORF42 PPP1R13B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
RHEB MTOR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18550814 16098514 25351248 15854902 15878852 16915281 33157014 15772076
CALM1 CAMKK1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
EPM2A PPP1R3C â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KRTAP3-3 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
RPTOR RRAGD â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ULK1 RB1CC1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8428476 23392225
ATG101 ULK1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
ATG13 RB1CC1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CDX4 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
KRTAP17-1 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
BANP TP53 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PFDN5 VBP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
BECN1 AMBRA1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 23974797
LZTS2 LZTS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 29395067
ULK1 MTOR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25686248 29321306 23524951 21460630
PPP1R3C STBD1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
MCL1 BECN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21139567 22219388 17446862
BECN1 TSC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 20562859
PRKAA1 PRKAG3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RRAGD RPTOR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18497260 24337580 26582740 22424946
SERTAD2 ZNF581 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
BECN1 ULK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
KRTAP4-2 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRTAP10-7 ZNF581 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RPTOR RRAGB â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ATG13 ATG101 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8428476 23392225
ULK1 ATG13 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26018823 21460630 32668203 27203176 33422265 19597335 33450483 23524951 33499712 23392225 32707033 21460634 18936157 25126726 32543267 29196462 25686248 20562859 27617292 30853401
KRTAP10-5 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PRKAG1 PRKAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 18480843 6767403
AMBRA1 BECN1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
KRTAP10-11 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRTAP10-7 KRTAP4-5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CRX ROR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LZTS2 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT31 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT31 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRTAP10-5 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CSNK2B ATG101 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KRTAP10-7 SPRY1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRKAA1 ACACB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12488245 12068056
LEPR CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21750978
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
PRKAA1 MLXIPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11724780 21892142
TP53 MRPL27 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
PRKAA1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14970221
TP53 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17409411 18431400
RB1CC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16061648 21775823
RB1CC1 ULK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19225151 18936157
TP53 RPH3AL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17409411 18431400
KRT40 ZNF581 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRTAP10-7 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRKAA2 PRKAB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT31 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT31 SPRY1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRTAP1-3 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRTAP10-7 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRTAP2-4 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRTAP10-11 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ULK1 RB1CC1 â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 19597335
MEOX2 TSR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MEOX2 SPRED1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRKAB2 PRKAG3 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
PRKAB2 IKZF3 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 8153045 21516116
ULK1 ATG13 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 19211835
KRTAP2-4 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP10-7 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP10-7 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP1-3 KRTAP10-11 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
RRAGA RRAGB â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RRAGD SLC38A9 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KRTAP2-4 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
MEOX2 VBP1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP2-4 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP10-11 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GYG1 GYS1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
TSC2 RHEB â—¼   GTPASE_REACTION ✅ - 0.91 0.91 Signor 15340059
KRTAP1-1 KRTAP2-4 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRKAB1 PRKAG3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
KRTAP1-1 KRTAP10-11 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP2-4 ZNF581 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP4-12 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ATG14 PIK3C3 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
LEPR LEP â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 9786864 8608603 33961781 22405007
KRTAP4-2 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-5 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP1-1 ZNF581 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-8 SPRY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-11 MEOX2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-8 KRTAP17-1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-8 ZNF581 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP2-4 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP1-3 SPRY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
MDFI SPRY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP1-1 SPRY1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-11 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-12 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
PRKAA1 PRKAB1 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17728241
KRTAP10-5 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-9 SPRY1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
MEOX2 SPRY1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-8 KRTAP4-5 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-8 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-12 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-2 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-5 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-9 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP9-8 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-12 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP1-1 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP1-3 KRTAP4-5 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP9-2 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-5 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-8 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP1-3 KRTAP10-5 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-2 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP1-1 KRTAP4-5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-1 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-1 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP4-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-1 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-5 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-8 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP9-2 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP9-3 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
MDFI ZNF581 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
MTOR RRAGA â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
KRTAP10-8 KRTAP4-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP4-2 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP4-5 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
MTOR ULK1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
KRTAP5-9 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-1 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP1-3 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-8 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP5-9 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
RRAGD RRAGB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 22424946 20381137 11073942 18497260 24337580 28716898
RB1CC1 ULK1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
KRTAP10-8 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP9-2 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP9-3 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
RHEB RPTOR â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RRAGB RRAGD â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
KRTAP5-9 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
PRKAB2 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PRKAB1 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
RRAGC RRAGA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 25936802 25567906 33961781 22424946 23184942 20381137 25561175 31601708 33157014 26186194 16713569 11073942 21981924 28514442 21816923 24337580 16189514 28716898
RRAGC RRAGB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 25567906 33961781 22424946 20381137 25561175 22980980 11073942 21981924 24337580 28716898
PRKAA1 PRKAG2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PRKAA2 PRKAG2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ATG13 ULK1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PRKAA1 PRKAB2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PRKAA1 PRKAG1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
RHEB TSC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MTOR RRAGC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
TSC1 TSC2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ATG101 ATG13 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
PRKAB2 PRKAG1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PRKAA2 PRKAB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAA2 PRKAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RRAGB SLC38A9 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAB1 PRKAG1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ATG14 BECN1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MTOR RHEB â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MLST8 MTOR â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RRAGA RRAGD â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RRAGB RRAGC â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPTOR RRAGC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RRAGA SLC38A9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RRAGC SLC38A9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPTOR RRAGA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RRAGA RRAGC â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CAMKK2 PRKAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
ATG101 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20562859 23392225 19597335
ATG101 ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 20562859 23392225 26299944 19287211 24290141 19597335 24100292
PRKAA2 ACACB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 14532170 12488245 9148944 20166139 12413941 14613924
AMBRA1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21358617 22441670 23030059 23377657 23974797
ULK1 AMBRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23524951 25438055 20921139
DYNLL1 AMBRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 27173435 20921139
AMBRA1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20562859 23974797 20711182 20417604 21358617 25438055 23954414 20921139 24587252 17589504 25499913 33562550
RPTOR ATG13 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11274345 11756498 12150925 12408816 12906785 15755954 16469695 17680028 18000759 18492954 19022819 19151919 19225151 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
MTOR ATG13 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11274345 11756498 12150925 12408816 12906785 15755954 16469695 17680028 18000759 18492954 19022819 19151919 19225151 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
MLST8 ATG13 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11274345 11756498 12150925 12408816 12906785 15755954 16469695 17680028 18000759 18492954 19022819 19151919 19225151 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
MTOR ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12150925 18000759 19225151 21157483 17680028 19151919 19864431 26801615 15755954 19446321 19258318 19706736 12408816 19211837 11274345 19211835 19568798
ULK1 ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15197469 19225151 21460630 18936157 27932573 19287211 19597335 27390127 27387056 27203176 25686248 26018823 20562859 23524951 33450483 26687599 19211835 23392225 26138443 25126726
ULK2 ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20562859 19225151 18936157
ATG13 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20562859 19225151 23392225 19597335 19211835
BECN1 ATG14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
PIK3C3 ATG14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
ATG14 PIK3R4 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
PIK3C3 ATG14 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 ATG14 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
ATG14 PIK3R4 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
ULK1 ATG14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27938392 29371398 30397185 23685627 29313410
ATG14 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 19270693 19050071 25594178 19223761 18843052 27513923 26496610 23954414 23332761 22081109 20562859 26108642 25891078 24034250 23112296 32296183 24980960 19270696 21062745 20711182 25490155
ATG14 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18843052 19270693 22493499 19050071
BECN1 PIK3C3 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3R4 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3R4 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3C3 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
MCL1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21353614 17446862 21139567
ULK1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 26390974 25545884 28301741 29734735 29233870 30292171 28518135 29313410 24191236 26546165 24848530 25026281 26921696 25026296 25373623 17595159 16940348 26108642 29371398 25891078 23685627 24370004 26008601 28238651 30397185 29233871 24834848 29867359
BECN1 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 18628207 36042481 19713971 19050071 16179260 25594178 21936852 18843052 24980959 28128446 25906440 26496610 26783301 23954414 19379691 23332761 20562859 23974797 24034250 16390869 24980960 19270696 25825496 19172397 20711182 23315026 25490155 24472739 17438366 23364696
BECN1 PIK3R4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20562859 18843052 20711182 18957027 25490155 26496610 19270696 19050071
CALM1 PYGM â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10487978 13115432 5461220 12825073
CALM1 CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9822657 11395482 10187789
CAMKK1 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14985505 21918180 8910387 14614828 23583109 15980064 14511394
CAMKK2 PRKAG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
CAMKK2 PRKAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
CAMKK2 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
CAMKK2 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 14985505 21918180 8910387 16054096 16054095 15509864 19197243 14614828 23625915 17244528 18692468 15980064 14511394 23583109
CAMKK2 PRKAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
CAMKK2 PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16051629 22561688 21228273 34044797 24959379 17244528 15980064 23716691 25065674 15465812 34421352 12413941 19197243 18692468 33502468 34216621 23863464 34064003 16054096 16054095 15509864 33675805 20538596 19958286 25937278 34290400 34253170 23612973 22304913
PRKDC CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19203584 28943433
TP53 CASP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19897582 16391794 18064040 16518869 12089322 24070868
TP53 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18431400 12089322
CDC14B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10644693 16713569
CSNK2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10606744 11709713 10214938 10951572 16713569 11551930 10747897 10673501 11883897
LEP LEPR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9463481 22405007 12226096 23331499 9207021 9218470 8608603 9786864
ROR2 MAGED1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 16713569 12754255
MAP3K6 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22286106 19935702 9875215 11689443 25852190 17210579
TP53 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11160159 19808698 11832478 18208354
MTOR MLST8 â—¼   PHYSICAL_INTERACTION 88.0 1.0 ACSN 10702316 10722653 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16556040 16678438 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17461779 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20027184 20138985 20338997 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025 9069260
MLST8 RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR MLST8 â—¼   SHARES_COMPLEX 88.0 1.0 ACSN 10702316 10722653 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16556040 16678438 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17461779 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20027184 20138985 20338997 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025 9069260
MLST8 RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR MLST8 â—¼   ENZYMATIC_REACTION ✅ 88.0 1.0 ACSN 10702316 10722653 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16556040 16678438 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17461779 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20027184 20138985 20338997 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025 9069260
MLST8 RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR MLST8 â—¼   LOCALISATION ✅ 88.0 1.0 ACSN 10702316 10722653 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16556040 16678438 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17461779 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20027184 20138985 20338997 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025 9069260
MLST8 RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RHEB MLST8 â—¼   UP_REGULATES ✅ 7.0 1.0 ACSN 12906785 16636147 17604271 18466115 19022819 19143635 23087689
RHEB MLST8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17604271 15854902 19299511 16636147 12718876 15878852 17470430 19143635 12906785 18466115
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RHEB MTOR â—¼   UP_REGULATES ✅ 7.0 1.0 ACSN 12906785 16636147 17604271 18466115 19022819 19143635 23087689
RHEB MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 18670866 18075516 18550814 16631613 18466115 16915281 23331499 15772076 16098514 20006481 15878852 21071413 23272152 19299511 15854902 19487463 20226003 19143635 17604271 16636147 17470430 12906785
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
MTOR ULK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 18000759 19225151 21157483 25759175 15755954 28464882 19446321 27681874 26417067 28518135 19706736 24119841 27325266 26906453 27731364 29686608 25026281 27935582 28366635 28674405 27617292 26869683 29507183 25679763 28389629 25686248 19568798 27387347 21383122 26118643 32134989 26887051 12150925 29540819 29849901 10995454 23136410 30093610 19864431 24358342 26844203 29787772 30127742 19690328 21460634 26447757 26589724 21258367 22770472 29057166 29752434 29066806 17680028 19151919 24998849 30174616 26734992 17595159 12408816 11274345
MTOR ULK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 12150925 19211836 18000759 19225151 21157483 17680028 19151919 19864431 15755954 19446321 19706736 12408816 11274345 19568798
PHKG2 PYGM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 75187414 16083285 22225877
PIK3C3 PIK3R4 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
PIK3C3 PIK3R4 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
PIK3R4 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20562859 27411398 8999962 18957027 21575909
TP53 PPP1R13B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11684014 18676979 14729977 18275817
PRKAA1 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19339977 33271062 14651849 16959574 15261145 28591720 18692468 20363874
PRKAA1 ULK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24820971 23372762 28295473 21460634 19584320 21205641 21258367 28389629 34421918 34224814 25980607 32978258
PRKAA1 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 18480843 8626596 17728241 21232561 16306228 8663446 25852190 8621713 23455922
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
PRKAA1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21460634 18439900
PRKAG1 PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20562859 10698692 26186194 9224708 17012231 16054041 25416956 31515488 32296183
PRKAA2 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18220336 19369195 18722121 18439900 20083114 19413330 18669648
PRKAA2 ULK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21205641 19584320
PRKAA2 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18692468 16959574 19339977 14651849
PRKAA2 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18692468 19339977 14651849
PRKAB1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18220336 19369195 21460634 18722121 18439900 19413330 18669648
PRKAB1 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18692468 19339977 14651849
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
ULK1 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20562859 19225151 23392225 19597335 25686248 26118643 19211835
TSC1 RHEB â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12906785 14551205 16636147 17604271 17680028 17693255 19022819 20146692
TSC2 RHEB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12906785 16636147 17680028 19022819 20146692
RHEB RPTOR â—¼   UP_REGULATES ✅ 7.0 1.0 ACSN 12906785 16636147 17604271 18466115 19022819 19143635 23087689
TSC2 RHEB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 15340059 15854902 23331499 16636147 12869586 17680028 21071413 20146692 12771962 20226003 12906785 12842888
TSC1 RHEB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17604271 16636147 20006481 17680028 20146692 14551205 17693255
RHEB RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17604271 15854902 19299511 16636147 24337580 15878852 17470430 19143635 16631613 12906785 18466115 25446900
RRAGC RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21816923 25561175 20006481 18497260 24337580 25446900 21981924
TP53RK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16600182 11546806 17712528
TSC2 TSC1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 12150915 12172553 12869586 12906785 14551205 14651849 15342917 15611338 15851026 16556040 16636147 16678438 16959574 17604271 17680028 17693255 18198340 18481918 18692468 18974095 19022819 19027299 19339977 20146692 21533173 21621563 21708191 23030059 26597054 27328425 9069260
TSC2 TSC1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 12150915 12172553 12869586 12906785 14551205 14651849 15342917 15611338 15851026 16556040 16636147 16678438 16959574 17604271 17680028 17693255 18198340 18481918 18692468 18974095 19022819 19027299 19339977 20146692 21533173 21621563 21708191 23030059 26597054 27328425 9069260
TSC2 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 84.0 1.0 Omnipath 12167664 16424383 12511557 21134130 14551205 10915759 11741832 15340059 20166753 23331499 15342917 9580671 21071413 16464865 15851026 11290735 9809973 15851513 12869586 10807585 15963462 10585443 11741833 20412061 20226003 11175345 25263562 16339216 18411301 16636147 14651849 17658474 17693255 12176984 17077083
TP53 FLNC â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368