AKT1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17611497
18954143
|
AKT1S1
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
AKT1S1
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
AKT1S1
|
MLST8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
FLCN
|
LAMTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
FLCN
|
LAMTOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
FLCN
|
LAMTOR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
FLCN
|
LAMTOR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
RRAGD
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HSPA5
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
MAF1
|
LAMTOR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SLC38A9
|
LAMTOR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25561175
25567906
|
SLC38A9
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
MLST8
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
MAF1
|
RRAGD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
RRAGB
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
RRAGA
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
MTOR
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
RHEB
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
MAF1
|
MTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
20543138
1005188107
|
RPTOR
|
MAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
MAF1
|
RRAGC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20516213
20233713
|
MLST8
|
RHEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
PRKAB1
|
PRKAA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6767403
18480843
|
PRKAB1
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21460634
21072212
|
RRAGD
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20006481
18497260
|
MLST8
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
MLST8
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
FLCN
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
FLCN
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
RRAGD
|
LTOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
20381137
|
LTOR2
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20381137
22980980
|
LTOR2
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20381137
22980980
|
RRAGA
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25561175
|
LTOR3
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25561175
|
HBXIP
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25561175
|
RRAGB
|
HBXIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25561175
22980980
|
CG059
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25561175
|
PRKAA1
|
PRKAG1
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
TSC2
|
MTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
12271141
|
LTOR2
|
HBXIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25567906
25561175
33961781
22980980
|
RRAGB
|
LTOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25567906
20381137
33961781
22980980
|
LTOR2
|
CG059
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25567906
25561175
33961781
22980980
|
LTOR2
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
20381137
25561175
22980980
25567906
|
RRAGD
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
20381137
25561175
|
CG059
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
RRAGB
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
20381137
25561175
22980980
|
HBXIP
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
HBXIP
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
HBXIP
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
CG059
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
CG059
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
RRAGB
|
CG059
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25561175
22980980
|
RPTOR
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ULK1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21795849
25686248
21460634
21460630
|
FLCN
|
LAMTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
MTOR
|
ULK1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
21460634
|
NPRL3
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
RHEB
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18550814
16098514
25351248
15854902
15878852
16915281
33157014
15772076
|
LAMTOR2
|
LAMTOR3
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
RPTOR
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
ULK1
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
8428476
23392225
|
ATG101
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
ATG13
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
NPRL2
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.86
|
STRING
|
36370105
|
RRAGC
|
LTOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
20381137
25561175
22980980
25567906
|
RRAGC
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
20381137
25561175
22980980
|
RRAGD
|
LTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
22424946
20381137
25561175
34079125
|
LTOR1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25561175
22980980
34079125
|
HBXIP
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
25561175
22980980
|
CG059
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
25561175
22980980
|
ULK1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25686248
29321306
23524951
21460630
|
RRAGC
|
NOL8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14660641
16713569
|
RRAGB
|
LTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
20381137
25561175
22980980
25567906
34079125
|
PRKAA1
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
RRAGD
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18497260
24337580
26582740
22424946
|
RPTOR
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
ATG13
|
ATG101
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8428476
23392225
|
RRAGA
|
LTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
25561175
31601708
22980980
25567906
21816923
34079125
|
LTOR1
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
22424946
20381137
25561175
22980980
25567906
34079125
|
AKT1
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12167664
15342917
12438239
12150915
|
ULK1
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26018823
21460630
32668203
27203176
33422265
19597335
33450483
23524951
33499712
23392225
32707033
21460634
18936157
25126726
32543267
29196462
25686248
20562859
27617292
30853401
|
PRKAG1
|
PRKAB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
18480843
6767403
|
TSC2
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
LTOR2
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
11266467
32296183
20381137
22939629
25561175
15016825
20655927
18479705
21988832
21516116
22980980
25416956
|
LTOR2
|
LTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
29123114
20381137
22939629
25561175
22980980
25567906
34079125
|
LTOR1
|
LTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
29123114
22939629
25561175
22980980
|
CG059
|
LTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
29123114
25561175
22980980
|
HBXIP
|
LTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
29123114
25561175
22980980
|
HBXIP
|
CG059
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
29123114
32296183
25561175
22980980
25416956
23414517
|
MTOR
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11438723
22337773
18505677
21045808
15718470
30639242
19299511
24670654
21177249
22084251
23872070
10910062
18566586
22307628
14970221
25792870
18566587
21343617
25241761
29567957
26293922
|
AKT1S1
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8008321
18372248
800723200
|
PRKAA1
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14970221
|
PRKAA2
|
PRKAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
AKT1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
MTOR
|
AKT1S1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
18372248
|
ULK1
|
RB1CC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
19597335
|
PRKAB2
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.9
|
STRING
|
36370105
|
ULK1
|
ATG13
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
19211835
|
LAMTOR1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
LAMTOR4
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
RRAGA
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
RRAGD
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
LAMTOR5
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
TSC2
|
RHEB
|
â—¼ GTPASE_REACTION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
15340059
|
LAMTOR4
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
PRKAB1
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
LAMTOR5
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
MTOR
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
21592956
|
PRKAA1
|
PRKAB1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
17728241
|
DEPDC5
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
NPRL3
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.93
|
STRING
|
36370105
|
YWHAB
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
12438239
5215924
|
MTOR
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
DEPDC5
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
MTOR
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
NPRL2
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
LAMTOR3
|
LAMTOR2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8153045
21516116
|
RRAGD
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
33961781
22424946
20381137
11073942
18497260
24337580
28716898
|
RB1CC1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
RHEB
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
RRAGB
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
PRKAB2
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
PRKAB1
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
RRAGC
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
25936802
25567906
33961781
22424946
23184942
20381137
25561175
31601708
33157014
26186194
16713569
11073942
21981924
28514442
21816923
24337580
16189514
28716898
|
RRAGC
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
25567906
33961781
22424946
20381137
25561175
22980980
11073942
21981924
24337580
28716898
|
PRKAA1
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
PRKAA2
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ATG13
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
PRKAA1
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
PRKAA1
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
RHEB
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
MTOR
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
PRKAA1
|
PRKAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
AKT1S1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
AKT1S1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
DEPDC5
|
NPRL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
RPTOR
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
24036451
|
MTOR
|
RPTOR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.98
|
0.98
|
mint
|
21045808
8088164
|
LAMTOR3
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
LAMTOR3
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
LAMTOR3
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
NPRL2
|
NPRL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ATG101
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
MTOR
|
RPTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.98
|
0.98
|
Signor
|
19346248
|
PRKAB2
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PRKAA2
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DEPDC5
|
NPRL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
LAMTOR3
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PRKAA2
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RRAGB
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
LAMTOR3
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
LAMTOR4
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
LAMTOR5
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PRKAB1
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
RHEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
MLST8
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RRAGA
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RRAGB
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
LAMTOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
LAMTOR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
LAMTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
LAMTOR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR1
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
LAMTOR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
LAMTOR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR2
|
LAMTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR3
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR3
|
LAMTOR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR3
|
LAMTOR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR4
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR4
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR4
|
LAMTOR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR4
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR4
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR5
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR5
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR5
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
LAMTOR5
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RPTOR
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RRAGA
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RRAGC
|
SLC38A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RPTOR
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
RRAGA
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ATG101
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
23392225
19597335
|
ATG101
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
20562859
23392225
26299944
19287211
24290141
19597335
24100292
|
MTOR
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
MLST8
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
AKT1
|
MLST8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
TSC2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
AKT1
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
SLC38A9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
MLST8
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
16697215
20398329
17461779
18372248
20338997
15808505
20138985
20214616
21474067
19203586
15718470
19568798
15169778
19720745
17517883
18925875
10949026
11715018
19143635
17277771
18636226
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
TBK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21329883
21464307
21106850
|
MTOR
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
24670654
16697215
11438723
21592956
20398329
17461779
18372248
21177249
21045808
20338997
15808505
16221682
20138985
20489726
15899889
20214616
8978681
21474067
14970221
19203586
17660512
15718470
19568798
20333297
23006971
15169778
25241761
18566586
19720745
17517883
18925875
22084251
10949026
14761976
11715018
19143635
17277771
18636226
10910062
15047712
9812896
18505677
21343617
19844585
17680028
19151919
18566587
9736715
23872070
10722653
20832730
18570873
17013611
17052453
12408816
15364915
11274345
|
AKT1
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
19376078
16340011
16083285
26506913
27784766
24467442
|
AKT1
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
63.0
|
1.0
|
Omnipath
|
18000759
17081983
17510057
12820960
21157483
11756412
11923280
16697215
19690332
19446321
20398329
17461779
18372248
19413330
15808505
20138985
23415227
20214616
12524439
20068231
14973226
19568798
18669648
17329361
15169778
12869586
17386266
19720745
17517883
11352916
10949026
11715018
19143635
17277771
18636226
19651622
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
AKT1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
18000759
21157483
11756412
11923280
16697215
20398329
17461779
18372248
15808505
20138985
20214616
19568798
15169778
19720745
17517883
10949026
11715018
19143635
17277771
18636226
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
AKT1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
75.0
|
1.0
|
Omnipath
|
16873412
12820960
17018601
11756412
32308763
11923280
16697215
19690332
21893193
20398329
18372248
21177249
12438239
18466115
15808505
29042482
20138985
15342917
17597835
20214616
12271141
16702951
20837138
17570479
26844273
15169778
17386266
10949026
16288292
24590173
11715018
15661536
18636226
18411301
20028854
9812896
16636147
20169078
17680028
12172553
19664994
18707149
10722653
12150915
18570873
20832730
12364343
17052453
18283331
21666717
27451907
|
AKT1
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
MTOR
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
17604271
17386266
18030348
28978182
19114562
17517883
26876939
18570873
18372248
17277771
|
RHEB
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17604271
17510057
16636147
12820960
12869586
17386266
19446321
19143635
17277771
18466115
|
AKT1S1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17604271
17510057
18030348
17386266
18215133
17517883
33230243
|
RPTOR
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12150925
18000759
19225151
21157483
17680028
19151919
19864431
26801615
15755954
19446321
19258318
19706736
12408816
19211837
11274345
19211835
19568798
|
ULK1
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
15197469
19225151
21460630
18936157
27932573
19287211
19597335
27390127
27387056
27203176
25686248
26018823
20562859
23524951
33450483
26687599
19211835
23392225
26138443
25126726
|
ATG13
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
19211835
|
MTOR
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RHEB
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17680028
18466115
18492954
19022819
19143635
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
26597054
28216025
|
MLST8
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RHEB
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17680028
18466115
18492954
19022819
19143635
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
26597054
28216025
|
MTOR
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RHEB
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17680028
18466115
18492954
19022819
19143635
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
26597054
28216025
|
RPTOR
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
DEPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
DEPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
DEPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
DEPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22017877
22017876
22017875
19446321
28086984
|
MTOR
|
MAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
17081983
20516213
18669648
31645432
20233713
19690332
20543138
|
MTOR
|
MLST8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
MLST8
|
â—¼ SHARES_COMPLEX
|
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
MLST8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
MLST8
|
â—¼ LOCALISATION
|
✅
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RHEB
|
MLST8
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RHEB
|
MLST8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17604271
15854902
19299511
16636147
12718876
15878852
17470430
19143635
12906785
18466115
|
MTOR
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RHEB
|
MTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RHEB
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
18670866
18075516
18550814
16631613
18466115
16915281
23331499
15772076
16098514
20006481
15878852
21071413
23272152
19299511
15854902
19487463
20226003
19143635
17604271
16636147
17470430
12906785
|
RPTOR
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
139.0
|
1.0
|
Omnipath
|
15268862
24403073
20427287
22258093
21321085
19446321
15467718
19875983
17461779
12665511
12719976
16631613
21045808
21177249
23911927
24337580
25446900
24516643
18614546
12718876
12747827
16603397
17043309
18519641
22544753
25007995
27043084
19145465
23953116
19619545
16919458
24375676
15459249
16837165
16847060
25332233
12150926
22424946
26348909
12150925
18955708
20381137
22356909
17386266
17565979
18030348
16354680
20169205
19114562
21071439
27329724
35561222
16798736
15809305
22493283
17277771
15661536
16962653
1683716516603397
17604271
18676370
16183647
18505677
23297343
23872070
24036451
15066126
18570873
21614075
18722121
12408816
17599906
|
MTOR
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
70.0
|
1.0
|
Omnipath
|
18000759
19225151
21157483
25759175
15755954
28464882
19446321
27681874
26417067
28518135
19706736
24119841
27325266
26906453
27731364
29686608
25026281
27935582
28366635
28674405
27617292
26869683
29507183
25679763
28389629
25686248
19568798
27387347
21383122
26118643
32134989
26887051
12150925
29540819
29849901
10995454
23136410
30093610
19864431
24358342
26844203
29787772
30127742
19690328
21460634
26447757
26589724
21258367
22770472
29057166
29752434
29066806
17680028
19151919
24998849
30174616
26734992
17595159
12408816
11274345
|
PRKAA1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19339977
33271062
14651849
16959574
15261145
28591720
18692468
20363874
|
PRKAA1
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24820971
23372762
28295473
21460634
19584320
21205641
21258367
28389629
34421918
34224814
25980607
32978258
|
PRKAA1
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
17145710
18480843
8626596
17728241
21232561
16306228
8663446
25852190
8621713
23455922
|
PRKAA1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21460634
18439900
|
PRKAG1
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20562859
10698692
26186194
9224708
17012231
16054041
25416956
31515488
32296183
|
PRKAA2
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
18220336
19369195
18722121
18439900
20083114
19413330
18669648
|
PRKAA2
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21205641
19584320
|
PRKAA2
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18692468
16959574
19339977
14651849
|
PRKAB1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
18220336
19369195
21460634
18722121
18439900
19413330
18669648
|
PRKAB1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18692468
19339977
14651849
|
ULK1
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
25686248
26118643
19211835
|
TSC2
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12906785
16636147
17680028
19022819
20146692
|
RHEB
|
RPTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
TSC2
|
RHEB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
15340059
15854902
23331499
16636147
12869586
17680028
21071413
20146692
12771962
20226003
12906785
12842888
|
RHEB
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17604271
15854902
19299511
16636147
24337580
15878852
17470430
19143635
16631613
12906785
18466115
25446900
|
RRAGC
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21816923
25561175
20006481
18497260
24337580
25446900
21981924
|