Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KLHL12 ARAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL12 BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 FAM90A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
FAM90A1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KLHL12 COL8A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL12 NDC80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DCUN1D1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PEF1 PDCD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SKP1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL12 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KLHL12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MED28 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LNX1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 KLHL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LNX1 PRR13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
KLHL12 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL12 CPSF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL12 MED28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL12 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL2 KLHL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
KLHL12 VTA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNX20 KLHL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CRTC3 KLHL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KLHL12 PRR13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLHL12 CRTC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
KLHL3 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8427680 23665031
DVL1 DVL2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
SYNE4 KEAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
UBXN7 RBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22537386 18775313
NTAQ1 NDC80 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBXN7 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
UBXN7 CUL4B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22466964 18775313 31973889
KLHL2 KEAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32296183 30190310 33961781 15383316
KEAP1 KLHL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 33961781
MED12 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 20133760 26496610 33961781
KLHL2 KLHL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32296183 33961781
MED28 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760
DRD4 KLHL12 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL3 PEF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27716508 21145461
FBXL17 KEAP1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
UBXN7 NEDD8 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24076655 22466964 22537386
CAND1 SKP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29499133 21145461 12504026
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL3 KLHL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 23838290 33961781 21145461
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
KEAP1 RBX1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DVL2 ARRB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 16189514 11742073
PDCD6 PEF1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CUL3 KLHL12 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RBX1 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 18247557 12481031
DVL1 DVL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24643799 28514442 20224554 33961781 26186194 31340145
KLHL3 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 23576762 23387299 25416956 23838290 26100637 23665031 23573258 25502805 25250572 30819806 33961781 26286618 23453970
DVL2 DVL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24643799 31340145 33961781 28514442
MED28 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 33961781 24981860 20133760
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
NEDD8 RBX1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
KEAP1 CUL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22911784 21357422 19818716 17822677 16449638 15367669 30765703 22558124 28186440 33130828 17439941 20599909 15282312 21145461 22448038 25742418 26757824 16790436 32296183 24896564 20534351 23727018 18251510 24127568 20027226 22245129 15983046 24322982 32341456 25628777 20421418 15572695 33391509 18417180 20865015 15601839 32854194 30273379 30383469 20864537 26219975
CAND1 RBX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29499133 18826954 12504025 15537541 12504026 30349055 12609982
CAND1 RBX1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PEF1 PDCD6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27716508 32296183 16189514 25416956 21988832 33961781 11278427 21516116 26344197
CAND1 SKP1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
COPS6 RBX1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
NEDD8 SKP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
NEDD8 SKP1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16503656 21145461 18247557 27705803
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
COPS5 RBX1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
PDCD6 SEC31A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CUL3 RBX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 19818716 15448697 12481031 11861641 30349055 25270598 20027226 22405651 26100637 19256485 11311237 19250909 25278611 26286618 20865015 15601839 19617556 29958295 33504946 12684064 24145166
DVL1 DVL3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32296183 10330181
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
RBX1 SKP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 12504025 12840033 12481031 26540345 11245432 29507117 10531037 16357137 30349055 15452136 12813041 23770852 29499133 12628165 11961546 29863914 33692209 27705803 33504946 12684064
CAND1 RBX1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DCUN1D1 RBX1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
SEC13 SEC31A â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
FBXL17 SKP1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CUL3 KLHL3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RBX1 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
POLD1 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
UBXN7 KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20452972 20495340 22872865 15983046
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
RBX1 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
POLD1 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RBX1 SKP1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 28380357 26117325 25040165 16286508 23274085
RBX1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 SKP1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
ARRB1 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11742073 20223821
KLHL12 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16547521 20970343
SKP1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
ARRB1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11742073 16713569
DVL2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12958364