Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAB3A PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RAB5B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ETF1 SEC61B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UFD1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ABCG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23838170 20600004
TP53 ANTXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11711532
FURIN ANTXR1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1644824 1438214
BLMH APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
TARDBP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FURIN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA4A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PINK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ICAM5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN4 BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KLHL12 BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
CASP3 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17581882
CCNB1IP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GET4 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDKN1A UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDKN1A RAB1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
TRIM28 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942393
TP53 CEBPZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12534345 5216050
CEP55 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP55 TSG101 â—¼   COLOCALIZATION 2.0 0.8 intact 17853893 6169256
EFEMP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EP300 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20339243 21467818
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP63 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15944736
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TTR GET4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15501971 12857899
HNRNPD MAP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBQLN1 HSPA13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBQLN4 HSPA13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HTT HSPA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA1A MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLR3F HSPA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PALMD HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PINK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF286A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IPO4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TRIM21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 IER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
VAPB KPNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YBX1 KPNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
TUBA4A MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
PINK1 MAP1LC3B â—¼   COLOCALIZATION 2.0 0.8 intact 20153330 7557104
RNF5 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20483786 19285439
RB1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218170 16374512
MECOM TEK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15889140
NOP2 NBEAL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 PRKAG3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
UBQLN1 PSEN1 â—¼   COLOCALIZATION 2.0 0.8 intact 5213196 11076969
PSEN1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19012753 18996842
PSMD4 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTN TOMM20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTN UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRIM27 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15837424
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TFCP2 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24150225 22615490
VCP RNF115 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN4 RPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SERPINI2 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBQLN4 SERPINI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SGTB SERPINI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBQLN4 SPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TP53 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11807984 16567167
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TP53 STX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SYVN1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SYVN1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 17170702 5219455
WDR83 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
USP13 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP YBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
TP53 ZDHHC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28775165
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
WDR83 TTR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP2 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
VCP VAMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOP2 RRP1B â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
AMFR DERL2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
PDCD11 PWP2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NPLOC4 UFD1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 20414249 7903886
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
C1QA SGTB â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
RAB1B RPN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RAB6B RAB6A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FAF2 UFD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
OXSR1 AIFM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 23455922
CFTR AIFM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
RAB8A BAG6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30804014 16169070
CFTR FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
DERL1 RPN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28137758 34079125
FAF2 HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25147182 18775313
VCAM1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NTRK3 MTOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 PI4KA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RPN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MRPL17 MRPL55 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST2H3C SIRT5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
VAPB CEBPZ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CFTR RAB5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26618866 19398555 21455491
RNF5 DERL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24019521 16901789 21594788
UBL4A GET4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 19615732 23246001 26186194 28514442
TRIM27 USP7 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
PSEN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
USP7 UVSSA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SEC61A1 SEC61B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MDM2 TP63 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TRAF6 USP7 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
DERL1 CFTR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26618866 16954204 16901789 18555783
VCAM1 TLN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22623428 19738201
FAF2 UBL4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DOT1L HIST2H3C â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CFTR FAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR RPN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
SYVN1 DERL1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16186510 29743537 16289116 24807418 23867461 19864457 26471130
VAPB VAMP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9920726 16189514
HIST2H3C IPO4 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CEBPZ PDCD11 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
XRN1 BAG6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15231747 26496610
UBL4A HUWE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 25147182
SGTB UBL4A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 26496610
RAB1B RAB1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 26344197
AMFR DERL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MAVS BAG6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32877691 21903422
UBL4A FAF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 23665563 23246001
LCK PI4KA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8246987 34079125
DERL1 FAF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AMFR BAG6 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CEP55 TSG101 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IKBKE MAVS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RAB1A RAB1B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAB1B RAB8A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CFTR STUB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RNF123 UBAC1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
RAB10 RAB8A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 17353931
RNF5 CFTR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19269966 16901789 21594788
DERL2 FAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MDM2 RB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SERPINI2 SGTB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PSMD4 VCP â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HSPA13 SGTB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CEBPZ PDCD11 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AMFR FAF2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
DERL1 SYVN1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
RAB10 ENOPH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UFD1 TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 AIFM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23506862 16729031
UBL4A BAG6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25713138 26344197 19615732 24981174 21636303 24581120 26496610 23246001 20676083 28514442 25535373
CDKN1A TUBB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSG101 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11943869 16189514
TFCP2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
RNF5 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16901789 17145710 21148293
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
VCP DERL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
SYVN1 DERL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10801418 15342649
TFCP2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21361876 25609232
HIPK4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18022393 20508833
HNRNPD MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
MAPK6 URB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TRAF6 MAVS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31390091 21903422 32511263 20080758 30527812 26221961 31806368 23545497 22908223 29125880 26385923 16153868 27348524
TP63 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11714701 9405685 12374749
TRIM28 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16107876
TSG101 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11172000 17060450
MDM2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20571051
VCP NPLOC4 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 20414249 7903886
PINK1 RAB8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 28860483 26471730 31361120
UBQLN1 SERPINI2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8153045 21516116
TP53 SYVN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
GET4 UBL4A â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HSPA1A STUB1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
LAMTOR5 MTOR â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TP53 SDC2 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
RPN1 SEC61B â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PSMD14 VCP â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
AMFR VCP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EP300 TCF3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
DERL2 SYVN1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PSMD4 UBQLN4 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
TSG101 CEP55 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6169256 17853893
TSG101 CEP55 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 6169256 17853893
DERL2 VCP â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PSMD4 UBQLN1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
UBXN1 VCP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
BAG6 GET4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GTF2F2 POLR2J â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
BAG6 UBL4A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
ASNA1 GET4 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
SYVN1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
FZR1 PTTG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SEC61A1 SEC61B â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMD14 PSMD4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NPLOC4 VCP â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TBX2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 20348948 16730707 25211658 19216023 15781639 11062467 18762810 20624445 15300007 17630961
TBX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 20348948 18025091 16730707 25211658 15781639 14996726 20624445 18829543 17630961 15459098
VCP UFD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23443559 16234241 26389662 16525503 18775313 26712280 27913212 15371428 20414249 26549226 16822850 18199748 23333620 17872946 19275885 24248593 20442859 27226613
NPLOC4 UFD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16322459 18775313 18586029 15371428 20414249 26389662 36087575 32296183 17202270 24248593 20442859 11574150
HSPA1A AIFM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11533664 12930708 16713569
AMFR VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20126661 22328510 16407162 16987818 17681147 26712280 16275660 21636303 17872946 18835813 19828134 22119785 23333620 23383273 26424800 21343306 21914798 16186510 15331598 17311810
APP GET4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
APP UBL4A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
MTOR ATP5G1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
HAVCR2 BAG6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 16286920 18055229 20819927 22437870 22863785 23414611 27192565 28900677
BAG6 LCK â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 16286920 18055229 20819927 22437870 22863785 23414611 27192565 28900677
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25241761 9660939 10022118 9799125
CASP3 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10822366 11420704 9092486
CASP3 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10069390 16189514
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
TP63 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15790310 10383130 21480565 12640112 20123734 17404570 16007146 16410722 15965232 12374749 17965458 21093383 23665236 9405685
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
TCF3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15138269 20194619
TP63 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9151818 19340300 19554267 21093383 19672307 8995628
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
CDKN2A HUWE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 16915296 15989956
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
HSPA1A DNAJA4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
FN1 SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10772816 1077281610772810
VAMP2 GET4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
GTF2F2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
HAVCR2 LCK â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 16286920 18055229 20819927 22437870 22863785 23414611 27192565 28900677
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
TP53 IER3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11844788 12360408
MAVS IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 15210743 16127453 19153231 17020950 25636800 15210742 16306936 12702806 16177806 27419230 36056146 19546225 19380491 16858409 21200404 24706939 18207245 17468758 17327220
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
MDM2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16374512 21990374 7791904 28615518 33185004 20871633 10078201
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
VCP NPLOC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 34262183 31623962 20442859 32814053
STK11 PRKAG3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 14511394 15579580 8779952 14985505 14614828 11018120
STK11 PRKAG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19197243 15509864 8910387 20160076
UBQLN1 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11076969 16815845 16713569 16813565
TP53 PTTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12355087 12403781 15016801
PTTG1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12355087 16713569
RAB5A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
RHO RAB8A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20308558 22433857 22983554 12221131 23567335 21273506
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
TP53 RNF123 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10562557 21422812 22085928 11593391
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
UBL4A VAMP2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
UVSSA USP7 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368
RAD54L RAD54L â—¼   KO_DOWN_REGULATES ✅ - -3.32 3.31 PKG 28854368