Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
E2F4 RAD54L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15782160 18319725
RAD54L EME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19017809 0807016105
RAD54L GPC4 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
ERCC4 MUS81 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MYC PFDN5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAD51 RAD54L â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MYC CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10918582 18444242 11258956
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
RAD51 ERCC4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 14734547 17962301 18541667
FANCM MUS81 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FBXO18 RAD51 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RAD54L CAV1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
E2F4 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11799066 20133863 21701264 17531812 17001309
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
RAD54L MUS81 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19017809
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
NDUFA4 NDUFA9 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFA9 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PTEN RAD51 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218252 17218262 18716620 19847259 22179046 22465479 23732914 24254977 25364523
WRN NDUFA4 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RAD54L TCEAL8 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
RAD54L CAT â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
RAD54L GNAS â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
RAD54L NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -1.23 1.22 PKG 28854368
MUS81 CAV1 â—¼   KO_UP_REGULATES ✅ + 1.25 1.25 PKG 28854368
RAD54L HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -1.66 1.65 PKG 28854368
RAD54L RAD54L â—¼   KO_DOWN_REGULATES ✅ - -3.32 3.31 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
RAD54L RPS4Y1 â—¼   KO_DOWN_REGULATES ✅ - -8.86 8.85 PKG 28854368