H2BC21
|
HNRNPU
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC21
|
YEATS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC21
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC9
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC9
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RAD54L
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19017809
0807016105
|
RAD51C
|
EME1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
XRCC3
|
EME1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
STAT3
|
EME1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20516069
18245483
|
HERC2
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22661230
22635276
|
RAD51C
|
MUS81
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
XRCC3
|
MUS81
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
PML
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12506013
16189514
|
RAD51C
|
SLX1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
RAD51C
|
SLX4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
XRCC3
|
SLX1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
XRCC3
|
SLX4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
DDB1
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
27354282
24412650
|
I23O2
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
NGN3
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CCL22
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
HERC2
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29426014
25476789
|
RBM33
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
KLK5
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
EME1
|
A4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
21832049
|
SUMO2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21147198
20016594
20016603
22689573
21693764
|
SLX4
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31495888
19596235
|
BRCA1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ERCC4
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
SLX1
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19595721
19596235
|
BRCA1
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14578343
11498787
|
SUMO2
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25027693
21148299
23543742
17000644
20797634
22155184
21779164
19553342
9452416
17081986
16713569
24637324
21693764
19471022
21252943
15940266
16189514
22578841
20826694
24190887
28851805
|
SLX1
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19595721
19596236
19596235
|
STAT3
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
12506013
|
SLX4
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31495888
32398829
19595721
19596236
19596235
|
SLX4
|
SLX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23093618
31495888
32398829
19595721
19596236
24012755
19596235
|
ERCC4
|
SLX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
SLX4
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22902628
31495888
32398829
19596235
|
SLX4
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23033263
29850896
21240275
21516116
25533185
23994477
22902628
31495888
19596235
32296183
23093618
32398829
19596236
28514442
25416956
29892012
23623386
19595721
24012755
25224045
|
FANCM
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
MUS81
|
SLX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
RAD51C
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
MSH3
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
16025128
8942985
22179786
22939629
8805365
14657349
9774676
10029069
19377479
|
BRCA1
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
STAT3
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
EME1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
EME1
|
CDK5
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CDK5
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
CDK5
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25038288
16651438
19156541
12763138
28114390
16879821
23941877
15096606
26198700
|
MSH2
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
STAT3
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
EME1
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
STAT3
|
EME1
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
MSH2
|
EME1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MUS81
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
POLM
|
EME1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15703371
16697054
16738138
17483519
17631059
19346677
19473888
19772495
19808869
19847258
|
SLX4
|
ERCC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23994477
24012755
21240275
24726326
22902628
23093618
19595721
19596235
25538220
20658648
19596236
19595722
|
MSH2
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MUS81
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
POLM
|
MSH2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15703371
16697054
16738138
17483519
17631059
19346677
19473888
19772495
19808869
19847258
|
MUS81
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MUS81
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
POLM
|
MSH3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15703371
16697054
16738138
17483519
17631059
19346677
19473888
19772495
19808869
19847258
|
POLM
|
MUS81
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15703371
16697054
16738138
17483519
17631059
19346677
19473888
19772495
19808869
19847258
|
RAD54L
|
MUS81
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19017809
|
RAD54L
|
RAD54L
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.32
|
3.31
|
PKG
|
28854368
|
MSH2
|
MSH3
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.7
|
5.69
|
PKG
|
28854368
|
MSH2
|
MSH2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-6.48
|
6.47
|
PKG
|
28854368
|