Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2BC21 HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 YEATS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 EME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 EME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 MSH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAD54L EME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19017809 0807016105
RAD51C EME1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
XRCC3 EME1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
STAT3 EME1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20516069 18245483
HERC2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RAD51C MUS81 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
XRCC3 MUS81 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
PML STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12506013 16189514
RAD51C SLX1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
RAD51C SLX4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
XRCC3 SLX1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
XRCC3 SLX4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
DDB1 MUS81 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 27354282 24412650
I23O2 EME1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NGN3 EME1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CCL22 EME1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HERC2 EME1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
RBM33 EME1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KLK5 EME1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EME1 A4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 21832049
SUMO2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21147198 20016594 20016603 22689573 21693764
SLX4 MSH3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31495888 19596235
BRCA1 MSH2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ERCC4 MUS81 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
SLX1 EME1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19595721 19596235
BRCA1 MSH3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 14578343 11498787
SUMO2 PML â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25027693 21148299 23543742 17000644 20797634 22155184 21779164 19553342 9452416 17081986 16713569 24637324 21693764 19471022 21252943 15940266 16189514 22578841 20826694 24190887 28851805
SLX1 MUS81 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19595721 19596236 19596235
STAT3 PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 12506013
SLX4 EME1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31495888 32398829 19595721 19596236 19596235
SLX4 SLX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23093618 31495888 32398829 19595721 19596236 24012755 19596235
ERCC4 SLX4 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SLX4 MSH2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22902628 31495888 32398829 19596235
SLX4 MUS81 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23033263 29850896 21240275 21516116 25533185 23994477 22902628 31495888 19596235 32296183 23093618 32398829 19596236 28514442 25416956 29892012 23623386 19595721 24012755 25224045
FANCM MUS81 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MUS81 SLX4 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RAD51C XRCC3 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
MSH3 MSH2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 16025128 8942985 22179786 22939629 8805365 14657349 9774676 10029069 19377479
BRCA1 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
STAT3 CDK5 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
EME1 CDK5 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
EME1 CDK5 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
STAT3 CDK5 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
CDK5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25038288 16651438 19156541 12763138 28114390 16879821 23941877 15096606 26198700
MSH2 EME1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
STAT3 EME1 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MSH3 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
STAT3 EME1 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
MSH2 EME1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MSH3 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
POLM EME1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258
SLX4 ERCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23994477 24012755 21240275 24726326 22902628 23093618 19595721 19596235 25538220 20658648 19596236 19595722
MSH2 MSH3 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MSH2 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MSH2 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MSH2 MSH3 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
POLM MSH2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258
MUS81 MSH3 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MUS81 MSH3 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
POLM MSH3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258
POLM MUS81 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258
RAD54L MUS81 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19017809
RAD54L RAD54L â—¼   KO_DOWN_REGULATES ✅ - -3.32 3.31 PKG 28854368
MSH2 MSH3 â—¼   KO_DOWN_REGULATES ✅ - -5.7 5.69 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368