CYCS
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9267021
5221616
|
APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
CASP8
|
CASP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18669646
0712034105
|
CASP9
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP3
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12011067
15573119
|
CASP3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17899380
|
CASP3
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9500443
|
CASP9
|
CASP7
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
GBF1
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19039328
7012768
|
HSF1
|
EEF1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8198070
21597468
|
HSF1
|
HSPA1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9869631
|
BCL2L13
|
HSPD1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
22921587
8391226
|
ESR1
|
HSPD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085516
|
NFKB2
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10595582
17855547
|
VCP
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
EEF1A2
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TBC1D20
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17684057
17562788
|
RAB1B
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217628
15796781
|
HSPA1L
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA1L
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA8
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NFKBIA
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
EEF1G
|
ARF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ARF1
|
GBF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8810314
9614177
|
IL1B
|
CASP8
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
1574116
22267217
|
EEF1G
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
NFKB2
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9523851
17082635
|
IL1B
|
CASP1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0812690106
19439663
|
NFKB1
|
TLR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19779021
12686724
|
RAB2A
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
GBF1
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19039328
7012768
|
OCRL
|
RAB8A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8184127
21378754
|
HSPA8
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ESR1
|
HSPA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085516
|
HSPA5
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NFKB2
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17982049
17579043
|
HSPA5
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11943137
|
CASP1
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667412
|
RAB11B
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ARCN1
|
COPZ2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
MYD88
|
TLR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
RAB1B
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
TOMM22
|
TOMM40L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
RAB1B
|
TBC1D20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
EEF1A1
|
EEF1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
RAB8A
|
BAG6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30804014
16169070
|
GDIA
|
RAB18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB5C
|
RAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB8B
|
RAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB5C
|
RPN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
RAB1B
|
RPN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
RPN1
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
CDC42
|
RAB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
26344197
|
ESR1
|
RAB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
RAB1B
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
RAB5C
|
ARF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
ARF1
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
LRRK2
|
COPG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
RAB7A
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
31871319
|
CDC42
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
26344197
|
RAB1A
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
GBF1
|
COPG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19039328
30567983
|
ESR1
|
COPG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25604459
31527615
|
RAB9A
|
PGTA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
OCRL
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
25107275
|
ESR1
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
SAR1A
|
SAR1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB8B
|
MSS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB5C
|
PGTA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
33961781
|
PGTA
|
RAE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB2B
|
GDIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB2B
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB8B
|
RAE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NAIP
|
NLRC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
COPG1
|
COPZ2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
827.0
|
0.82
|
STRING
|
36370105
|
ARF1
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
RAB1B
|
PGTA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RAB1B
|
RAE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MYD88
|
TLR5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15107846
17583698
16482509
|
CASP8
|
NLRC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12646168
27974463
20085538
|
CASP1
|
IL1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
7797510
28147281
8999548
32122970
7642516
1919001
19439663
|
RAB1A
|
MSS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
33961781
12788069
|
COPG1
|
COPZ2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11056392
14729954
10921873
33961781
|
RAB8B
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26824392
|
MICALCL
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
C3
|
ITGAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CHM
|
RABGGTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
RAB8A
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32017888
26824392
|
PGTA
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
33961781
7991565
|
PTPN11
|
ERBB2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
32024694
|
RAB11B
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CASP9
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11242052
8900201
25241761
1067155
15941357
11230124
15507451
18723680
17437405
|
LRRK2
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21048939
21454543
|
USO1
|
GBF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12634853
31519766
|
GDI2
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
APAF1
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
PYCARD
|
CASP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
34589402
|
RAB11A
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
HDAC6
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20029029
31980649
|
CYCS
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9390557
|
CASP8
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15254227
11832478
18669646
11437602
8962078
|
COPB2
|
COPE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22939629
10921873
9482852
33961781
|
RAB9A
|
RAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
29568061
|
RAB1B
|
GOGA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11306556
15796781
|
RAB1B
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31046837
26824392
|
RAB1B
|
MSS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
|
RAB1B
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26186194
26344197
|
HDAC6
|
MYD88
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31268348
29281743
20837465
|
VPS52
|
VPS54
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25799061
27440922
20685960
|
RAB9A
|
RAE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
29568061
34079125
|
RAB8A
|
OCRL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
16902405
5218938
|
RAB8A
|
OCRL
|
â—¼ COLOCALIZATION
|
✅
|
|
0.87
|
0.87
|
mint
|
8184127
21378754
|
RAB5C
|
RAE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
|
CASP3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GOLGA2
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
COPG1
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
RAB1A
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
RAB1B
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
COPG1
|
COPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
9751720
14729954
33961781
22939629
26344197
|
COPG2
|
COPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14729954
22939629
|
COPE
|
COPG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
10921873
33961781
27684187
22939629
26344197
|
RAB1B
|
RAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
26186194
9437002
|
RAB5C
|
RAB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
RAB1B
|
OCRL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32203420
25107275
|
ARF1
|
ARF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
26344197
|
TLR2
|
CD14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18765807
10395652
16189514
|
GDI1
|
RAB8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
RAB5C
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
GDIB
|
RAB7A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29360040
26344197
|
RAB7A
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
GDIB
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
10512627
16189514
|
GDIA
|
GDIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
|
RAB5C
|
RAB8B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
ESR1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
GDI2
|
RAB11B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
GDI1
|
RAB11B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
NFKBIA
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
RAB11B
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
COPG1
|
COPE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
9751720
22863883
10921873
33961781
22939629
26344197
|
RAE1
|
PGTA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
21905166
|
RAB1B
|
RAB8B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
MYD88
|
TLR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17126326
15107846
16482509
16293622
29990310
|
HSPA8
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
GDIA
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11583574
16189514
16713569
|
USO1
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10903204
16189514
22228731
16473624
|
GOGA2
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
22228731
12788069
11718716
11739401
|
RAB1A
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26824392
|
RAB1A
|
RAE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9730828
8294464
33961781
28514442
|
COPB2
|
COPG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
9751720
14729954
22863883
10921873
33961781
22939629
26344197
|
COPG1
|
COPG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
22939629
11056392
33961781
|
COG3
|
COG7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
19536132
22863883
33961781
26186194
22939629
26344197
|
GDIA
|
RAB7A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
29360040
26496610
|
RAB7A
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
26344197
26496610
|
GDIA
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26496610
|
GOGA2
|
RAB2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
11739401
16189514
25416956
|
RAB11A
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
EEF1A1
|
EEF1A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
RAB11A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
NFKB2
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
NFKB2
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
GDI1
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
RAB1A
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CASP3
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9367996
29752472
|
NAIP
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15280366
|
HSF1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18367728
21266308
10328874
|
RAE1
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
8294464
33961781
|
ESR1
|
C3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10418989
8961270
17478088
|
IL1B
|
MYD88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17507369
17890055
9430229
|
NFKB2
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15079071
8413215
8413306
|
RELA
|
IL18
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10227974
17399992
15963597
|
RELA
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19088195
17082476
|
NFKB1
|
IL18
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10227974
17399992
15963597
|
CASP1
|
IL18
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
1574116
9121587
8999548
|
NFKB1
|
COPB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14743216
27609421
21988832
35140242
25609649
|
OCRL
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32203420
16902405
25107275
|
RAB1A
|
USO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16473624
10903204
|
COPG1
|
COPZ1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
8858162
9482852
9751720
22863883
11056392
33961781
18356299
22939629
26344197
|
GDIB
|
RAB9A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
33961781
34079125
10512627
|
RAB9A
|
GDIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
26496610
33961781
34079125
7744738
|
OCRL
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29125462
16902405
26824392
|
HSPA8
|
HDAC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
ARF4
|
GBF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17956946
22389062
23567335
|
MSS4
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16541104
29125462
33961781
26824392
|
NLRC4
|
CASP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17418785
11472070
11374873
11390368
15107016
|
IL12B
|
IL12A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10899108
10779781
7527811
|
USO1
|
GOGA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
10931861
22792062
9150144
34079125
9478999
9753325
29568061
|
GDI2
|
RAB8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
HSF1
|
HSPA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
COPB2
|
COPG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
14729954
22939629
|
COG3
|
COG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
RAB1B
|
RAB8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
GDI1
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
COPA
|
COPZ1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
9751720
22863883
33961781
22939629
26344197
|
RAB1B
|
RABIF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
COPB2
|
COPZ1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
22863883
33961781
22939629
26344197
|
MYD88
|
TLR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
GDI2
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
GDI1
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
COPB2
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
CHM
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
RAB8B
|
GDIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
28514442
26344197
|
RAB1A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
COPA
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
COPG2
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ERBB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
RAB1B
|
GDIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
16713569
8836150
33961781
26186194
|
RAB1B
|
GDIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
33961781
26186194
26344197
|
COPZ1
|
COPG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
22939629
11056392
26344197
33961781
|
RAB5C
|
GDIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
33961781
34079125
|
RAB8B
|
GDIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
33961781
26344197
|
COPB1
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ARCN1
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
COPE
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
COPG1
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
COPB2
|
COPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
9482852
8537409
9751720
14729954
22863883
10921873
8940050
22939629
26344197
|
RAB7A
|
RAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
12576024
9563513
|
GDIB
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
28514442
20176951
33961781
22939629
26344197
|
RAB1A
|
GDIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
28514442
22939629
26496610
33961781
19942850
26344197
|
GDI2
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
IL12A
|
IL12B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
COPB1
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAB11B
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
COPE
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
COPE
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
C3
|
CR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
CASP9
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5221774
9390557
|
GDIB
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
26824392
29125462
10512627
25860027
26344197
|
RAB8A
|
GDIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
26824392
29125462
26496610
33961781
26344197
|
GDI1
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
GDI2
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
COPA
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
COPB1
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
ARCN1
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
COPA
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
TLR4
|
MYD88
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17126326
15107846
10952994
17258210
18221795
20048342
15728506
33052227
12646618
11743586
21911421
21829704
|
NFKB1
|
NFKB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
14743216
27609421
21988832
17962807
15169888
35140242
25609649
15660126
|
COPB2
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
COPB2
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
RAB8A
|
RABIF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
COPB1
|
COPE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
OCRL
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CASP1
|
PYCARD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
VPS52
|
VPS54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
COPB2
|
COPE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ARCN1
|
COPE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
NFKB1
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
COPE
|
COPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8858162
9482852
9751720
31712447
10921873
33961781
16169070
27684187
22939629
26344197
|
ARCN1
|
COPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ARCN1
|
COPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
COPA
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
COPB1
|
COPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ARCN1
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
COPA
|
COPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NFKBIA
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CYCS
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
11753565
10393175
10364241
15829969
16977332
15907471
10722681
9390557
10578178
16713569
9267021
12147322
10206961
10329646
11112785
10940292
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
HSPA1A
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10934467
16713569
|
APAF1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
17145710
15829969
15024710
9390557
19494828
11113115
10617566
9539746
10364241
10722681
27476169
21060833
19118655
20829884
16977332
10329646
15210107
10393175
16352606
11242052
14555243
10376594
12773388
10206961
19337385
10428850
9488720
19788417
15262985
9922454
21827945
10749135
9651578
19698783
12792650
9837928
11227497
|
CASP8
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15755874
17179148
9501089
9950028
18669646
23308069
10988287
18458084
16964285
9885230
9765224
11437602
15014070
21295084
8962078
9208847
|
CASP9
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10708865
9390557
10508159
11230124
18723680
15657060
16977332
15507451
1067155
9708736
25241761
8900201
11242052
9765224
17437405
19788417
9812896
12620238
15941357
12181739
19465923
12792650
15725726
|
CASP9
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9390557
25313070
20462491
27697150
|
CASP7
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
16916640
9922454
11752425
11701129
12824163
|
CYCS
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19788417
16977332
9390557
16713569
12147322
12773388
10329646
12792650
15210107
|
CASP9
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17899380
9922454
16352606
9598997
9651578
|
USO1
|
COPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
COPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPA
|
COPE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
COPA
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPA
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPB1
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPE
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPE
|
ARF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPE
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPE
|
USO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
HSF1
|
HSPA1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21932106
24041570
21085490
19336471
20692357
11423545
18434628
|
HSF1
|
HSPA1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9699716
21932106
16460681
2674689
16012946
24041570
1508207
22797943
9011567
1717345
17897941
20692357
23212905
23874968
|
HSF1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23733891
23636453
24532586
10328874
11893605
22105779
11866474
17766920
|
HLA-B
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11513144
11994457
8976179
8986721
9605119
9751747
|
PTPN11
|
IL1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
1238444
12393695
12421919
12707331
15169881
15240681
15699106
15713798
16204085
17307799
19406987
19479342
19833085
20363967
20435894
21469115
22483603
22683124
22955274
27557510
9751747
|
PTPN11
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
1238444
12393695
12421919
12707331
15169881
15240681
15699106
15713798
16204085
17307799
19406987
19479342
19833085
20363967
20435894
21469115
22483603
22683124
22955274
27557510
9751747
|
PTPN11
|
CXCL8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
1238444
12393695
12421919
12707331
15169881
15240681
15699106
15713798
16204085
17307799
19406987
19479342
19833085
20363967
20435894
21469115
22483603
22683124
22955274
27557510
9751747
|
PTPN11
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
26.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
1238444
12393695
12421919
12707331
15169881
15240681
15699106
15713798
16204085
17307799
19406987
19479342
19833085
20363967
20435894
21469115
22483603
22683124
22955274
27557510
9751747
|
PTPN11
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9756944
16273093
16729043
32024694
|
PYCARD
|
NLRC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
19104081
23702978
23940371
26885855
27048821
27066895
27984721
|
PYCARD
|
NLRC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
19104081
23702978
23940371
26885855
27048821
27066895
27984721
|
CD14
|
PYCARD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
PYCARD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
PYCARD
|
IL1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
19104081
20385749
23202296
26885855
27048821
27066895
27439607
27984721
|
PYCARD
|
NLRC4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
19104081
23702978
23940371
26885855
27048821
27066895
27984721
|
CASP1
|
PYCARD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
24630722
25605870
12191486
15383541
11051551
11967258
11536016
24803432
21385879
26121674
11432859
12019269
16585594
19337385
14634131
|
TNF
|
CXCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
IL6
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
ESR1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23733894
15334655
16483936
12237295
20664923
|
NFKB1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17513725
12058956
24337575
12657243
17704137
12471036
17707233
7624137
11259437
12686724
16433741
26114754
20237317
7876168
16707469
12117498
14976218
10485496
15465827
8622636
15812247
21138578
18990758
10748079
15013838
15749903
16916598
17646159
10754326
16040075
10837498
18285351
11675405
11739517
15743782
20066113
20617556
17085785
8530146
8805669
10919279
14960579
1740105
10963848
16055086
9742085
17292554
10553096
11312646
15543947
17442180
16285952
10079106
11297551
10551799
10201927
12907458
8679226
9281604
22782967
8219230
11749970
9916895
11094063
11490006
7895918
1618817
16483936
18057724
20722069
16569682
9452482
17407192
17082635
|
RELA
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
136.0
|
1.0
|
Omnipath
|
26596471
17707233
20817730
12686724
27075886
21765477
21537341
19530226
17390058
18077329
15064230
20617556
8805669
17351769
23335080
21573233
17292554
16285952
9916895
11749970
7895918
17496784
12628924
23857586
12657243
15857826
12471036
11259437
16433741
9831247
20237317
15465827
26023919
22661093
10748079
15013838
17350185
10754326
15470505
11827962
20139176
26408955
22901690
18772140
21108432
22742857
23195252
18362169
24012417
11312646
17442180
9281604
10079106
11297551
15081318
22718766
24908318
8219230
26004152
11094063
11490006
9916692
16483936
18057724
16569682
22138107
18467438
20547752
22723832
19846753
17407192
20221401
19854828
20534538
7876168
16707469
12117498
20544543
23178569
15812247
21138578
12610112
25888873
16916598
16040075
28039105
14749357
20066113
19285436
25161822
22388040
14960579
20195282
16199883
15543947
23971673
10551799
11290773
22798670
22021035
20722069
20221720
27338466
19385047
12058956
26997758
25690886
7624137
20686703
26114754
14976218
10485496
17607667
8622636
11007957
18285351
10837498
11739517
18719026
17268554
17085785
17142966
10963848
9742085
23042817
27534992
10553096
26516703
20696864
10201927
16850160
8679226
21098092
20097764
9129150
17082635
|
TNF
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
15192014
27329558
22240205
15833743
19351843
28187781
15841081
28107185
28373828
26999213
24386331
24957606
26179215
21572963
18258304
28317833
29441018
10722927
19596989
28423685
12881425
25118327
24036851
28089769
21904602
24141032
10938077
30201812
20691659
24166907
19789307
19393267
22768286
26310932
19411070
23789107
28790310
29708974
20507904
|
TNF
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
19053972
24083678
25215581
29088783
24386331
25888769
20460401
16866128
19934328
9363938
24349153
|
NFKB1
|
CXCL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8530498
7479086
15958549
10530453
16040075
11112786
|
RELA
|
CXCL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16799643
8530498
15958549
10530453
16617094
16040075
25734337
11112786
16825293
|
ITGB2
|
CD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
10201950
16751103
3537192
2462607
|
C3
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
4062888
26293614
|
COPB2
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPZ1
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
22013193
16926190
15813748
17956946
12047556
12634853
17429068
18524849
16030262
16633337
|
ARCN1
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
22013193
20357002
17429068
18524849
16030262
16633337
|
GBF1
|
RAB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22013193
16926190
15813748
17956946
12047556
17429068
18524849
16030262
16633337
|
RAB1B
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
RAB1B
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
RAB1B
|
COPZ2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
C3
|
CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10382758
2551147
9988761
2141838
|
C3
|
ITGAM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
4062888
11073102
26293614
|
CHML
|
RABGGTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
11675392
22694141
16401880
11141079
8513495
18532927
|
NFKB1
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
1829648
21725609
23178297
23572150
8096091
|
RELA
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18204072
17876798
24083678
15499023
25759022
23422506
12859951
7775482
11744993
22723832
23450368
11060311
12885753
18981184
9250151
|
NFKB1
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17876798
15499023
17709515
7775482
11744993
10454561
11060311
12885753
9250151
|
NFKB1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
17145710
25609649
7862124
1340770
16210649
16970925
21719482
9738011
9865693
10497169
8657102
9572494
9315679
21988832
8887676
10329681
1829648
14743216
17003112
11313474
20558726
26496610
7867065
7891711
10837071
7831327
15836773
26186194
11571291
15214841
17561400
16846590
9566883
8096091
15371334
7479976
11020244
9426183
16493424
15145317
8631829
20237821
20980497
16513645
9597130
7479848
7739549
7628694
10655476
|
RELA
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
134.0
|
1.0
|
Omnipath
|
17145710
15657065
11801607
25609694
15226358
17003112
9057089
26496610
19219072
23850221
7831327
12927781
16683270
17301240
17561400
9566883
10391945
8887633
16209943
21719482
10066434
8657102
10581242
29734393
21988832
12419806
14743216
16105840
15671248
9751059
9990853
25759022
10498867
8246997
7878004
11020244
9426183
15845455
26476452
23563313
16951195
25520503
9694722
11287411
10329681
15799966
17612295
24457201
10085161
10837071
10969074
11571291
9573251
15214841
16846590
20065107
7479976
24248593
8887627
15145317
16493424
9135156
24634218
7479848
15024091
14636585
26463447
7862124
1340770
22081069
8139561
27923823
16970925
9738011
9865693
9572494
11231305
14685242
20797629
11313474
16226509
14690596
22022389
21217772
26186194
30213788
15371334
8978697
20980497
7739549
7628694
|
MYD88
|
CD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16267105
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
IL18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
IL18
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
CD14
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16267105
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
CXCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
TLR5
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16644730
16410796
20855887
15107846
16482509
17583698
|
TLR4
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22664090
19717524
20048342
21911421
9625770
17228323
17258210
11743586
15107846
15728506
12888566
21829704
18221795
10952994
17635639
17126326
12646618
|
TLR2
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
22673208
19717524
22664090
20348427
16893894
15107846
29990310
16798732
16482509
16293622
17126326
|
CD14
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
RELA
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
114.0
|
1.0
|
Omnipath
|
26596471
19124729
10373597
9523851
23595969
28270510
21537341
17982049
15226358
18243142
12200447
20371366
24664372
23874122
14532843
18942706
10975857
21278793
10469356
22547075
17490702
11459775
23335080
10569191
19707556
19687301
7499267
8290595
23857586
24676671
18061164
11058167
12887736
15013753
15158360
22661093
20935672
20511231
17350185
10903137
16112536
27413250
21810609
16984731
16166627
18469854
12881425
24012417
23386688
22105366
8752656
12176740
27371733
22578249
18057724
20351184
10329846
19164127
10542237
11564778
20221401
15517885
19122653
20534538
7876168
27211851
9516466
18996370
8824277
18310089
21104991
25888873
12359431
11327783
20066113
20100571
19703987
19469019
21106671
16960103
18502099
16043358
21996739
20650996
22021035
11120852
12672795
12058956
18483242
22189669
14976218
17495236
11007957
21131967
11975924
27337441
9182853
10963848
17040605
11504280
15756023
10823821
17932106
19966855
20696864
12177065
8679226
9199307
17196927
20457835
21098092
17532054
|
NFKB1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
71.0
|
1.0
|
Omnipath
|
17513725
18061164
12058956
24337575
19124729
15611045
11058167
9523851
15517885
12887736
15158360
7876168
17495236
25549935
17982049
15241416
18243142
9516466
2405250
18996370
8824277
18310089
24664372
15749903
10903137
16112536
14532843
11327783
18942706
11975924
20066113
16984731
10975857
11160296
19703987
22895549
10963848
10469356
22547075
17040605
11459775
17490702
19469019
8247545
11504280
15756023
10569191
10823821
20696864
12907458
19707556
16043358
11035101
12176740
11302724
8679226
8725624
22578249
8752656
17196927
17532054
12727841
18057724
7499267
10329846
9199307
9502421
19164127
11120852
24676671
11098847
|
RELA
|
CXCL8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15079071
15536066
17550372
19171876
23430059
8383323
9743347
|
RELA
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
129.0
|
1.0
|
Omnipath
|
12820969
24337575
15289496
9405619
9698090
20038977
15057743
21665565
24260304
10817569
14631383
10969814
15005855
19668231
16325549
19732956
8207232
18281166
27856305
23894194
9388261
26340924
10975857
10745031
20194077
10928981
16553947
17565687
16764699
22848596
15531761
16105834
16803583
9510190
15355994
18221537
12643600
20053934
11716760
8617886
12218154
12707271
23637609
27076634
8878392
17917246
12163591
16829531
16818736
14670967
12038622
15958549
18362169
8413215
19734226
23386688
11297551
15950427
17362989
16455661
27371733
11953364
8413306
18074095
11973337
18786178
19376732
19837667
17276517
15517885
11342414
18669446
7876168
15350531
14645117
22891766
18034886
11564889
12748173
17586662
18996370
15223809
17041011
12485925
16004996
15079071
21343296
26618242
18435575
17636245
22340043
19173296
24634218
11120852
10477716
21343177
12058956
17045242
19786024
24048734
24770886
10202011
18309103
11864912
21131967
19064995
10530453
12716652
16418726
28283022
18723827
17040605
21255844
15615716
17932106
19966855
20696864
15387324
21451502
15722553
15879558
12855659
12883201
15688424
18045535
10506755
|
ESR1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15208657
16029657
19440537
14991571
18669446
17932106
|
NFKB1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
9510190
12058956
11973337
18786178
17045242
15289496
16701870
19376732
19837667
9698090
17276517
11512674
19786024
20038977
10202011
15057743
15517885
12643600
11342414
7876168
15350531
18034886
11716760
11564889
11864912
12218154
12707271
10969814
12748173
14631383
16325549
17586662
18996370
19732956
17041011
10530453
18281166
12716652
16418726
12485925
16004996
9388261
8878392
17917246
10975857
10745031
10928981
16553947
16818736
14670967
18435575
12038622
15958549
17040605
8413215
21255844
22340043
1401924
9452482
16764699
11297551
15950427
15387324
15879558
16105834
11953364
15688424
18074095
8413306
11096450
16803583
10506755
11120852
10477716
|
TLR4
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21737330
12752666
15814722
16115877
14739303
21737329
|
CD14
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21737330
12752666
15814722
16115877
14739303
21737329
|
CASP8
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18073771
9545235
10872455
18329793
9727491
9463409
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RELA
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
12820969
14688340
20221401
11058167
10657616
10940886
19122653
18690006
11792125
19624579
17982049
9464836
17924060
7565674
14976188
15251981
12077291
17579043
24012417
19299558
16166378
12517966
17635610
24184907
15270850
20876114
9808189
|
RELA
|
CXCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
14597166
27889620
24634218
15722553
15666090
17363596
17449583
21507677
18362169
28266569
15132979
27076634
12914794
16166378
|
RELA
|
NFKB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9056676
9528780
15755876
7541912
|
RELA
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
26596471
27338466
11114294
8413223
20975042
17707233
23383347
11058167
12686724
16433741
23667107
15382119
19122653
24009751
27211851
18566416
15292915
20617571
23056550
12517972
18285351
19843519
22267743
15812237
25161822
22388040
8021507
9878621
14960579
10963848
23195252
11395507
27534992
9058643
15543947
19846753
20696864
8679226
24908318
28389361
27371733
15972680
20336759
10080875
17082635
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
RELA
|
IL12A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
14568984
17982049
17579043
20876114
19122653
22070873
18690006
19164128
19185846
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
IL1B
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25606026
26999213
22240205
23666959
19197368
25306394
24009751
|
TLR2
|
CD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16455995
17889651
10426996
15241424
16880211
|
TLR4
|
CD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
22078883
16467847
22158869
18233961
18297073
14517279
|
CD14
|
ITGAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
10201950
16751103
3537192
2462607
|
CD14
|
CXCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
CD14
|
TLR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11745332
17535871
12196527
32196115
|
CASP1
|
IL18
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22270365
17039247
15326478
9121587
9334240
|
LRRK2
|
RAB8A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
30209220
32227113
32017888
26824392
29357897
29308544
29482628
|
NFKB1
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8413223
17707233
11058167
12686724
16433741
18285351
8021507
9878621
14960579
10963848
9058643
15543947
20696864
8679226
11035101
15972680
20336759
18772363
10080875
17082635
|
CASP1
|
IL1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
1919001
7642516
7797510
17039247
28147281
8999548
19439663
9121587
|
NFKB1
|
CXCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17363596
28266569
15132979
15722553
|
NFKB1
|
IL12A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
14568984
11602633
17982049
17579043
15871905
18690006
19164128
|
NFKB1
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
14688340
11058167
10657616
10940886
18690006
11792125
17982049
9464836
17924060
7565674
14976188
9234715
12077291
9497375
17579043
19299558
22427889
16166378
15270850
9808189
|
NAIP
|
NLRC4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
23702978
23940371
26885855
27048821
27066895
|
USO1
|
SEC22B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
SEC22B
|
SAR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
22013193
10982397
23378591
20545907
18843296
10825291
20679433
11035026
|
SEC22B
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
21532587
24917561
20966969
17287728
|
SEC22B
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
GDI2
|
RIC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
27246931
19620288
19109890
21183348
11689439
10990452
25341920
15878329
23091056
18367545
21421921
|
GDI1
|
RIC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
27246931
19620288
19109890
21183348
11689439
10990452
25341920
15878329
23091056
18367545
21421921
|
RAB9A
|
VPS52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
18195106
25343031
16885419
19620288
18946081
17488291
8440258
|
RAB8A
|
RAB11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
20308558
22433857
22983554
12221131
23567335
21273506
|
ARF4
|
RAB11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
17007872
17628206
17030804
19153612
18685082
22983554
23567335
|
USO1
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
RAB1A
|
GOLGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11285137
11718716
11739401
16189514
12788069
|
USO1
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
ARF4
|
ARCN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
ARCN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARCN1
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
COPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
COPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPB2
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
GBF1
|
COPG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
CHM
|
RIC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
27246931
19620288
19109890
21183348
11689439
10990452
25341920
15878329
23091056
18367545
21421921
|
RAB9A
|
VPS54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
18195106
25343031
16885419
19620288
18946081
17488291
8440258
|
ESR1
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
24559156
16115928
16467118
17992604
19915977
15199112
21127199
21761336
21907803
20551150
11713584
1358436
20629094
18768663
19005469
9242384
20889718
10698518
16467117
|
ERBB2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
15173068
|
USO1
|
ARF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
22013193
20357002
11726511
17429068
25436559
18524849
16030262
16633337
|
ARF4
|
COPZ2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
ARF4
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
22013193
20357002
17429068
18524849
16030262
16633337
|
ESR1
|
CAV2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12711000
12138116
18414489
|
CHML
|
RIC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
27246931
19620288
19109890
21183348
11689439
10990452
25341920
15878329
23091056
18367545
21421921
|
CASP1
|
NLRC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
15190255
15383541
15882992
17418785
11472070
15107016
11051551
11536016
17382568
11432859
17470531
11390368
11374873
|
IL12A
|
IL12B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
10779781
10899108
8943050
7527811
|
USO1
|
COPZ2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
COPZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
18283113
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
USO1
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
22013193
16926190
15813748
17956946
12047556
12634853
17429068
18524849
16030262
16633337
|
GBF1
|
COPZ2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|
COPZ1
|
GBF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
Reactome
|
1680566
16926190
22013193
8505331
10318838
17451557
1631136
17360540
9751720
21844168
8132710
9114004
10921873
1957170
1898986
22304919
16940185
|