Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SP1 ABCC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374464 17214963
SP1 ADAM17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19772640
TP53 ANTXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11711532
FURIN ANTXR1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1644824 1438214
ANTXR2 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
FURIN ANTXR2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1644824 1438214
PACS1 AP1G1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16977309 5219086
NGF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MMP2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FURIN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP NGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOX9 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21862616 19254573
CEBPB FURIN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8132667
F7 F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 11560488
F10 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25769543 35114109
SP1 F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12911579
F2 PROC â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 468991 2538457
SERPINA5 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12878585 18362344
F7 F9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 2248955
F9 F7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2040636 2248955
F9 F7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2248955 12524220
MMP2 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP2 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
VWF FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11700320 3155520
KRT6C FURIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SERPINH1 FURIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPM FURIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TGOLN2 FURIN â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
FURIN GORASP2 â—¼   COLOCALIZATION 2.0 0.8 intact 20608975 7897361
MSTN FURIN â—¼   CLEAVAGE ✅ 2.0 0.8 intact 8432598 23829672
FURIN MMP11 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 7746327 8645182
FURIN VWF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8218226 1571548
NOTCH1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
HIF1A NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
SP1 MMP11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22227581
MMP2 MMP14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8314771 8530478
MMP2 MMP14 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8314771 8530478
MMP14 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21909923 21900405
MMP16 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23691193 24376839
TP53 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
PPARA PCSK9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16794006 18245819
SP1 PROS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16672217
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
SP1 SOD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18314536
MMP14 FURIN â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20608975 21152186 8804434
TGFB1 MMP2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10652271 25241761 16189514
SGTB SOD3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
IPSP FURIN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FCGRN FURIN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FCGRN FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
5HT3A FURIN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FURIN ATE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34709727
LITAF FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TP53 FBN2 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
AP1G1 AP2M1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
ACPL2 FURIN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 34709727
AP2M1 NAGPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
F2 PROC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CEBPB SP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12665574 12847250 16651265
AP2M1 FURIN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10593987 16713569
ACE2 AP2M1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33436498 34709727
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PACS1 FURIN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11331585 9695949
IPSP PROC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 2551064 11123896 16189514
SP1 ADAM17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19772640 22705645
ADAM17 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19601831 19726682 19704010
ADAM17 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19601831 19726682 19704010
ADAM17 NOTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19601831 19726682 19704010
ADAM17 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9774383 12535668
CEBPB FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8183933 12184911 21562223
SP1 F10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8567696
SP1 F7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9716591 8618898
FURIN FLG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11380615 15803139 16061697
SP1 FURIN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8132667
PDGFB FURIN â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15207811 1639841 10508235
PDGFA FURIN â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15207811 1639841 10508235
FURIN MMP14 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11830519 8804434 8621565
FURIN NOTCH1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9244302 10075724 10935626
FURIN MMP16 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11830519 8804434 8621565
NOTCH1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18722525 23331499 16256737
PPARA IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17981503 12816998 14580308
SP1 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592504 16716598 11013220
SP1 MMP28 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20144149 11574168
SP1 NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22609358 16135093 21123453
SP1 PROC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15933209
SERPINA5 PROC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11123896 16189514
PROS1 PROC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 1615482 2461936
SP1 PROS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14652633 20200160 16672217
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
SP1 SOD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20079429 15451065 18314536
AP2M1 TGOLN2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
F2 SERPINA5 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
TP53 PCSK9 â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
HIF1A ARNT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12391259 10085255 16954218 7836384 17916562 26496610 8663540 34592152 14764593 20603618 14668441 21512126 11606485 26350169 9079689 24056783 19845609 27684187 11782478 19168635 23363003 26160453 28628118 15850782 17197389 21620138 15833858 23086815 24434214 20458141 18024476 23458834 12810720 28514442 15347669 9704006 27320910 20562859 11829741 15031145 21435239 20049704 15479785 20932347 12393189 11025203 16861921 9159130 10671489 16520375 15615775 17213817 28205554 23796364 15319539 11593383 19251694 20699359
GPIHBP1 LPL â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
FURIN ACE2 â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 33493182 32532959 34929169 35343766 34561887 32512386 32362314 33494095 34732583
ADAM17 NOTCH1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 18676862 19601831 19704010 19726682 22006996
FURIN ADAM17 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 22246777 22246778 12755693 14623079 25795784
ADAM17 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10882063 19726682 19704010 19601831 9620803
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
TGFB1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12867422 25241761 16189514 2119582
ARNT MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 15592504 1823643 16716598 12829734 9159130 13130303 9746763 12080085 11566883 10403805 8943284 15451019 9278421 16887934
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
SP1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11684680 8055923 12700237 21820092 8910434
CEBPB BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15713650 16772287 16720721 18843047 11668178
CEBPB INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18310298 8288055 12665574
CEBPB IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10995751 15878863 16331681 17556653 19521987 11312260 11009091 8634139
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
F9 F10 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 2105717 1958666 2303434 7803238 1346975 26023895 3965513
F2 VWF â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
FURIN TGFB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 14557817 16474430 17934056 20519943 21900405
LPL FURIN â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 20581395 26933753 26934667 8020465 24397894 10900462 16109723 26934567 17088546
TGFB1 FURIN â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11141505 11390472 12482908 7737999
FURIN GPIHBP1 â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 20581395 26933753 26934667 8020465 24397894 10900462 16109723 26934567 17088546
FURIN TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16474430 17934056 20519943 21900405 14557817
FURIN NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22479394 9653148
IFNG HIF1A â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
HIF1A TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16896927 17053163 15611046 19211927 21209004 21057546 21055290
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
SMAD2 IFNG â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
SP1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24019072 17023546 12576336 8756632 18793716 9503023
SP1 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1311316 18310298 7776968 15131018 12706836 12665574 7983788 16707431 22033326
TP53 LITAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 21836606 17283168 15197774
PPARA LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10774955 15713663 12208475 10634806 8895578 12042669 9226459 14960661 16890192
PPARA LPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20813756 18391971
MMP14 MMP2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11112697 18037882 18633355 22880008 23737743
SP1 MMP14 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SP1 MMP14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15592504 18927121 23394613 17534446 14979875 12093818 10721699 18568943
MMP14 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8663332 14583471 24376839 23691193 11857380
SP1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16453304 19061309 19853299 16575904 21045016 10506168 21520171 21469139 15317818 17258390 19126647
TP53 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18980971 22451655 23048035 10029407 9343394 19853299 11792711 19939245 17088079 17258390
MMP2 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10652271 25241761 16189514 21900405
PDGFB PDGFA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9334164 10508235 1311092 8900172
TGFB1 PDGFA â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
SP1 PDGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15297375 9453298 9321833 9351401 22964636 7499234 10364563 11823426
TGFB1 PDGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 16474430 17934056 18403754 20519943 16607286 21900405 11133108 14557817 15548370 19920116
SP1 PDGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22415074 11222751 15175554 11967988 8662647
SMAD2 SP1 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696
SMAD2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19558215 10878024 12631740 11013220 11114293
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 NOTCH2 â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
TP53 NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.64 1.63 PKG 28854368