Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FOXD4L6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F4 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
MMP9 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP9 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
THBS1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11606713 10900205
PTEN SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12804776
SP1 KLF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353772
THBS1 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10900205
VTN ELN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN FBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN FBN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP4 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP3 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ATL1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT ATL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FBN2 MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP2 MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP4 MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MMP2 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP2 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOXL1 MFAP5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
ELN LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MFAP2 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOXL1 FBLN5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX MFAP5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MFAP3 MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
FBN1 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN1 MMP13 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 MMP12 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
LOX FBN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN1 FBLN5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19570982
LOX FBLN5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
ELN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
ELN MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN LOX â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 MMP12 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
LOX FBN2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 MMP13 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN2 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
LOX MFAP2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MFAP2 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
F19A3 INSR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN408 FBN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN408 FBLN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZFP41 FBLN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN408 FBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRG3 FBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VWCE FBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LYPD4 FBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
F19A3 FBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ATL1 FBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZFP41 FBN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FX4L6 FBN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ZFP41 FBN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MATN2 FBN2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12180907 16713569
MFAP5 FBN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 12122015
FBN1 ELN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19570982 10825173
SP1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353772
SP1 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12055073 21880723 7896792
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP1 FURIN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8132667
LOXL1 FBLN5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19570982 16713569 14745449
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
KLF8 MMP9 â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
SP1 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1311316 18310298 7776968 15131018 12706836 12665574 7983788 16707431 22033326
SP1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16453304 19061309 19853299 16575904 21045016 10506168 21520171 21469139 15317818 17258390 19126647
FBLN5 ELN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18267938 19570982