Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MFAP4 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP4 MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP2 MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN2 MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN LOX â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX FBLN5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX MFAP5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX FBN2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX FBN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX MFAP2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP2 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN1 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP3 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP3 MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ATL1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT ATL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F4 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
TP53 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20428827
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
E2F4 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
VTN ELN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
ELN MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
ELN LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
VTN EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
LOXL1 FBLN5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN1 FBLN5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19570982
VTN FBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MMP2 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP9 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 MMP13 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 MMP12 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 MMP13 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN2 MMP12 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
VTN FBN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN2 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MMP2 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP9 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FOXD4L6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 KLF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353772
LOXL1 MFAP5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MFAP2 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
VTN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
THBS1 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10900205
TP53 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
THBS1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11606713 10900205
TP53 PRDM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 PRG3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12135761
PTEN SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12804776
ZN408 FBLN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 FBN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F19A3 FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F19A3 INSR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ATL1 FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZFP41 FBLN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VWCE FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRG3 FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LYPD4 FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TP53 FBN2 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
FX4L6 FBN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFP41 FBN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFP41 FBN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TP53 MFAP2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
MATN2 FBN2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12180907 16713569
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MDC1 FBN2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
MFAP5 FBN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 12122015
FBN1 ELN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19570982 10825173
SP1 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12055073 21880723 7896792
LOXL1 FBLN5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19570982 16713569 14745449
SP1 FURIN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8132667
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353772
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
FBLN5 ELN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18267938 19570982
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
SP1 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1311316 18310298 7776968 15131018 12706836 12665574 7983788 16707431 22033326
KLF8 MMP9 â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
SP1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16453304 19061309 19853299 16575904 21045016 10506168 21520171 21469139 15317818 17258390 19126647
TP53 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18980971 22451655 23048035 10029407 9343394 19853299 11792711 19939245 17088079 17258390
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
TP53 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17311279 15899818 17077165 18635530
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12609716 10719731 10101800 24195060 10029407 16406676 19826414 9833779 12719977 9017002 22028325 10224095 9849855 7521539
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368