Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HOXA1 LTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
MFAP4 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP4 MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP2 MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN2 MFAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
HOXA1 FBLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ELN LOX â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX FBLN5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX MFAP5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX FBN2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX FBN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
LOX MFAP2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP2 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ELN MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN1 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP3 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MFAP3 MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
SP1 ADAM17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19772640
MMP2 DCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9148753
HOXA1 EFEMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SGTB EFEMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VTN ELN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
HSPD1 ELN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ELN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
ELN MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
ELN LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
ITGB1 EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215947 12456677
VTN EMILIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ENG ITGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8410211 22940691
ENG ITGA5 â—¼   COLOCALIZATION 2.0 0.8 intact 8410211 22940691
HOXA1 FBLN5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FBLN5 LTBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220035 17581631
LOXL1 FBLN5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN1 FBLN5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19570982
VTN FBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
HOXA1 FBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
MMP2 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP9 FBN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 MMP13 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 MMP12 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN1 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
FBN2 MMP13 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
FBN2 MMP12 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
VTN FBN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
FBN2 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MMP2 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
MMP9 FBN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 10229672 10386589
HOXA1 LTBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
VTN ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7716514 32196115
LOXL1 MFAP5 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
MFAP2 LOXL1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 6123066 16906757
SP1 LTBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23741501
VTN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
VTN MFAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
MMP1 MMP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 7780967 1371271
PPIH ZMAT2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
SP1 TAL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8058326 9786909
TGFB1 VTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11796824 16189514
TGFB1 MMP2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10652271 25241761 16189514
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ZN408 LTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 FBLN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 FBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 LTBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 FBN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD026 NUDT8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD026 LTBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD026 FBN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
ZFP41 FBLN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZFP41 LTBP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFP41 FBN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFP41 FBN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFP41 LTBP4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ITGB6 TGFB1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
FBLN2 ELN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10544250 16713569
FBLN2 FBN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9886271 16713569 8702639
DCN TGFB1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EFEMP2 TLX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HOXA1 SPRY2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
LTBP1 TGFB1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MFAP5 FBN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 12122015
FBN1 ELN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19570982 10825173
HMGA1 SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12665574 20335021
EFEMP2 SGTB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LTBP1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8432736 21677751
SP1 ADAM17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19772640 22705645
ADAM17 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14970227
SP1 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12055073 21880723 7896792
LOXL1 FBLN5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19570982 16713569 14745449
FBN1 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TAL1 FBN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20028976
SP1 FURIN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8132667
IGF1R IGF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26027733 8452530 21645859
MMP1 MMP2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 8194591 7981201 8015608
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
SP1 SPRY2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17599098 14644509
HOXA1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
ITGAV TGFB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
VTN ITGB6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8120056
TGFB1 LTBP1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10025398 10544215 11133108 11766992 14557817 15548370 15611103 16139227 16474430 16710477 17934056 18342983 18423981 18802007 19010789 19109155 19741094 19854168 19909365 19920116 20519943 20535745 20644162 21278795 21883891 21900405 21909923 22703233 23620508 25732845 26552706 26711338 7594497 8570922 9314552 9931372
TGFB1 LTBP1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10025398 10544215 11133108 11766992 14557817 15548370 15611103 16139227 16474430 16710477 17934056 18342983 18423981 18802007 19010789 19109155 19741094 19854168 19909365 19920116 20519943 20535745 20644162 21278795 21883891 21900405 21909923 22703233 23620508 25732845 26552706 26711338 7594497 8570922 9314552 9931372
PLG IGF1 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7527330 17047378 8964575 11739083 7588299 8894645 12466191 12379487 10990447
PLG ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15247268
LOX EFEMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19570982 19855011
FURIN ADAM17 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 22246777 22246778 12755693 14623079 25795784
ADAM17 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22413019 14970227 30455686
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
FBN1 EFEMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19570982
EFEMP2 ELN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19570982
FBLN5 ELN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18267938 19570982
EMILIN1 TGFB1 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 14557817 16474430 17934056 20519943 21900405 2190045
EMILIN1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16474430 17934056 20519943 21900405 14557817 2190045
FURIN TGFB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 14557817 16474430 17934056 20519943 21900405
TGFB1 FURIN â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11141505 11390472 12482908 7737999
FURIN TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16474430 17934056 20519943 21900405 14557817
HGS SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11094085
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
MMP1 IGF1 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGF1 MMP2 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
SP1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10720440 21447702 7497000 15345673 17170218 7491107 17049831 17014845 10982795 17486080
SP1 IL1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17312152 11051106 17906119 21139583 15863387
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
SP1 ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22227038 18775869 15825163 24130169
VTN ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11331280 23154389
VTN ITGAV â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
SP1 ITGAV â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10504395 23319049 12136940 23345412
VTN ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23154389
VTN ITGB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2412224 2420006 7685013 7542669
VTN ITGB3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
VTN ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16195248 11331280
SP1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16453304 19061309 19853299 16575904 21045016 10506168 21520171 21469139 15317818 17258390 19126647
MMP2 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10652271 25241761 16189514 21900405
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
MMP9 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10652271 21900405 25241761
SMAD2 SP1 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696
SMAD2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19558215 10878024 12631740 11013220 11114293
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845