MFAP4
|
EMILIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
MFAP4
|
MFAP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
ELN
|
MFAP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
MFAP2
|
MFAP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
FBN2
|
MFAP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
ELN
|
LOX
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
LOX
|
FBLN5
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
LOX
|
MFAP5
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
LOX
|
FBN2
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
LOX
|
FBN1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
LOX
|
MFAP2
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
FBN2
|
MFAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
MFAP2
|
MFAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
ELN
|
MFAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
FBN1
|
MFAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
MFAP3
|
EMILIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
MFAP3
|
MFAP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
SP3
|
BGN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9786935
15372625
|
VTN
|
ELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
HSPD1
|
ELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ELN
|
MFAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
ELN
|
MFAP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
FOSL1
|
ELN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19682489
10559225
|
SP3
|
ELN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8910531
12055073
|
ELN
|
LOXL1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
VTN
|
EMILIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
LOXL1
|
FBLN5
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
FBN1
|
FBLN5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19570982
|
VTN
|
FBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
FBN1
|
LOXL1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
VTN
|
FBN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
FBN2
|
LOXL1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
SMAD3
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17637743
25374926
|
SP1
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15158147
19302822
|
SP1
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16288017
13679379
|
HIF1A
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15794924
19828020
|
HIF1A
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19934262
15780936
|
JUN
|
IL13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21989417
15494506
|
RELA
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17310108
10646503
|
LOXL1
|
MFAP5
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
MFAP2
|
LOXL1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
6123066
16906757
|
VTN
|
MFAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
VTN
|
MFAP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
TGFB1
|
VTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11796824
16189514
|
SP3
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
12414801
11517158
10825178
16734381
9329821
23825960
12200149
15247906
|
HIF1A
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.81
|
STRING
|
36370105
|
FBLN5
|
LYOX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19570982
25118846
|
FBLN2
|
ELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10544250
16713569
|
FBLN1
|
ELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10544250
16713569
|
HIF1A
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25879517
19738058
11739718
|
TGIF1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11427533
32814053
11306568
|
JUN
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
FBLN2
|
FBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886271
16713569
8702639
|
DCN
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
RELA
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
SP1
|
SP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MFAP5
|
FBN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
12122015
|
LYOX
|
ELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19570982
12686141
30082873
6912069
|
FBN1
|
ELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19570982
10825173
|
MFAP5
|
FBLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
16713569
12122015
|
SP1
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25879517
16478997
17215518
16713569
33572115
10506225
|
SP1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10878024
11114293
22227581
12228247
11432852
16714330
|
TGFB1
|
BGN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10383378
16189514
8093006
|
MYBL2
|
CLU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15618219
10770937
|
FOSL1
|
CLU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10406964
|
SP1
|
ELN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12055073
21880723
7896792
|
LOXL1
|
FBLN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19570982
16713569
14745449
|
SMAD3
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10903323
10220381
11306568
21829441
9732876
|
SMAD3
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12374795
10022869
|
SP3
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9329821
15247906
10825178
|
FOSL1
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
JUN
|
FOSL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11912197
33961781
11431474
11708771
23661758
9160889
24029232
20511396
26258633
|
SMAD3
|
LOX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11013125
11074002
11279127
11376132
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21098712
21614932
22331441
22652804
23784029
25374926
8515656
9389648
|
HIF1A
|
LOX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19828020
20956321
18037992
21239473
17685448
|
LOX
|
EFEMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19570982
19855011
|
JUN
|
DCN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
7499226
8798756
8940199
|
FBN1
|
EFEMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19570982
|
EFEMP2
|
ELN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19570982
|
JUN
|
ELN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11967999
1281483
11557580
10559225
1637804
12135766
|
FBLN5
|
ELN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18267938
19570982
|
EMILIN1
|
TGFB1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
6.0
|
1.0
|
ACSN
|
14557817
16474430
17934056
20519943
21900405
2190045
|
EMILIN1
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16474430
17934056
20519943
21900405
14557817
2190045
|
SMAD3
|
FGF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11013125
11074002
11279127
11376132
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21098712
21614932
22331441
22652804
23784029
25374926
8515656
9389648
|
HIF1A
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19492421
16399861
17536272
17942638
|
JUN
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9456251
10913304
10559225
11281649
11551904
23485603
23331079
|
JUN
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18435914
15806162
13679379
17082637
|
JUN
|
FOSL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9160889
11708771
23661758
20511396
11431474
24029232
11912197
|
IL13
|
HIF1A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
11.0
|
1.0
|
ACSN
|
12223527
12401408
14610620
14657224
15099563
18250477
18451175
20184663
21097505
26755705
9535722
|
RELA
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18498249
17898080
23185316
|
HIF1A
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16896927
17053163
15611046
19211927
21209004
21057546
21055290
|
IL13
|
LGALS3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
12223527
12401408
14610620
14657224
15099563
18250477
18451175
20184663
21097505
26755705
9535722
|
SP1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20148354
8355696
8892460
1406636
19437621
9054614
17502875
|
JUN
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8058069
16327802
16730810
23437118
8183578
16365456
22429882
23936544
15546613
10843986
16978906
23762330
7521696
8631909
12794825
|
SMAD3
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
9732876
10220381
11306568
21829441
10903323
|
RELA
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18174238
9468519
16713569
10488148
|
SP1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7636984
8450395
9151857
20538607
11964305
|
RELA
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19385047
23195252
28148567
14600158
16365456
21255844
15051419
|
RELA
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12055073
7933095
10671503
20861353
|
TGFB1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
TGFB1
|
SMAD3
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SP1
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
TGFB1
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
SMAD3
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26553048
27974707
10708950
19214138
|
TGFB1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21557273
24899689
24075003
24485922
28756206
32196115
|
SP3
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21554857
12509426
9632663
10362515
19223508
15857802
20096088
16806531
15854045
15118068
9788252
12773549
16617124
11517158
12554796
9666093
15869407
12888570
11287330
15541732
8845379
16574784
8070411
|
SP1
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12186868
9580699
2808430
12615726
22415074
27974707
12138160
10964912
9242631
15178441
23437118
23936544
11114293
8325508
16714330
11278686
10212284
9837963
11054406
23806282
15979845
|
SP1
|
ZBTB7A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19444642
23027183
19723341
18368381
|