Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SHANK3 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 SHANK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HNF1B ACE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100303 16297991
CTSL ACE2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 22816037 19321428
ADAM17 PTPN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215697 12207026
TFRC ALB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8412643 23384347
HNF1B ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671480 1673926
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
HNF1A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19782160 17848139
CFTR PDZK1 â—¼   COLOCALIZATION 2.0 0.8 intact 5213120 11051556
ESR1 TMPRSS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19013008 18414489
ESR1 ITGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
HNF1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11522780
FN1 ITGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
SHROOM2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KDM1A FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
FYN SNX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HSPA5 MAST1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KDM1A MTF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PIAS4 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
VIM SENP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SRY SLC9A3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9054412 5221357
SLC9A3R2 SRY â—¼   COLOCALIZATION 2.0 0.8 intact 5217948 16166090
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ANGT GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACE2 ANGT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11815627 15283675 33453855 10969042
SKP2 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AAMP ACE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17289570 23403292 31527615
ACE2 SHAN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33436498 34835087
ACE2 SNX27 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33436498 34835087
CFTR SLC9A3R2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ACE2 NHRF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34189428 34709727 34835087
CFTR GRP78 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833 17110338
GRP78 ACE2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33965375 34615619
CALM ACE2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19164471 18070603 34709727
AP2M1 FURIN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10593987 16713569
CALM1 ESR1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CFTR UBR4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
ESR1 CALM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33731348 31527615 11981030
ACE2 AP2M1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33436498 34709727
CFTR PDZK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CD9 ITGB1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
FN1 ITGB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ACE2 NHRF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33436498 34189428 34835087
ACE2 S6A19 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32132184 34189428
ATG9A AP2M1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33436498 24603492 27934868 34799561
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
HNF1B HNF1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10484768 35140242 33961781 2044952
TMPRSS2 ACE2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 21325420 21068237 20926566
CFTR SLC9A3R1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
SLC9A3R2 CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 12369822 5215811
SLC9A3R1 CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6548022 9671706
NHRF1 CFTR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15553237 9671706 19446522 17244609 26618866 31324722 12471024 12615054 28360110 10852925 12403779 17110338 9677412 11158634 9613608
NHRF3 CFTR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15553237 11051556 12471024 18045536 12615054
ACE2 SLC6A19 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
FN1 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1694173 1532572 17015452 18480047
FURIN ACE2 â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 33493182 32532959 34929169 35343766 34561887 32512386 32362314 33494095 34732583
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
FURIN ADAM17 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 22246777 22246778 12755693 14623079 25795784
ADAM17 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22413019 14970227 30455686
HNF1A AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20978123 17475670 1515023
HNF1A ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8443410 12760745 8262148 11939905 2736625 8288579 1321810 1487491 10542313 14561216 22196858 8102976 1942067 15598887 7519016 1685988 8626635
TGFBR2 CCL2 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
SLC9A3R1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 9671706 12471024 15553237 17110338 10852925 17244609 9677412 28360110 18754678 12403779 11158634 19446522 11304524 9613608
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ITGB1 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FN1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FN1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7688313
FN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9842903 22451694 17015452 18480047 19738201 7688313 1694173 6325925 25237190 26456826 10772816 7626807 21985969 6284125 1532572 11010812 8120056
ITGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
ITGB1 LYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479