Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDKN2A CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDKN2A CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
CDKN2A SUMO2 â—¼   COLOCALIZATION 2.0 0.8 intact 6541703 18259216
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
SENP3 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7941484 19680224
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HIF1AN EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12573436
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
TP53 HIC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
H1-5 MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
UBC NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
NPM1 KMT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
PELP1 NPM1 â—¼   COLOCALIZATION 2.0 0.8 intact 21326211 8149485
NPM1 SENP3 â—¼   COLOCALIZATION 2.0 0.8 intact 6541703 18259216
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18314489
SPRED1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 SENP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 RPS4X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
TAF1 TAF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22711989 16407123
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
DAXX TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 14557665 5216762
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
WDR5 CHD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7542690 20085832
VIM SENP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VIM BECN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1225967 23112296
VIM SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BECN1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218776 16810318
HIF1A HIF1AN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24421387 19726677
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
SENP3 HIF1A â—¼   COLOCALIZATION 2.0 0.8 intact 7941484 19680224
SP1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
CDK4 MEF2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21902831 25733682
UBC SENP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7941484 19680224
RPS8 RPS11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR1H2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17218271 20159957
SUMO2 RNF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SENP3 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PELP1 MDN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21326211 8149485
SENP3 PELP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21326211 8149485
ADRB2 SENP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
H1-5 SENP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SENP3 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H1-5 TEX10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BAP18 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H1-5 TBC1D32 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LAS1L WDR18 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BOP1 RRP1B â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
KAT8 PHF20 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
EP300 NPM â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29746960 16107701 33742100
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
SUMO2 DNM1L â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21693764 32786267 29128334 23524851
DOT1L UBC â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
LRRK2 STUB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DOT1L NPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20431927 26496610
UBC MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 19166840 6823655
RRP1B NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
WDR5 TAF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15960975 32076268
TAF6 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14580349 23292512 22939629 26344197
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
WDR5 TAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15960975 32076268
DHX15 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26511642
WDR5 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15960975 24930734
LRRK2 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 LAS1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 MDN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 17400507
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
NOP56 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
ESR1 NPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 33731348 21182205 20348541
IFIX PELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
IFIX SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
NOL9 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PHF19 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TR13B SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFIX LAS1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
TR13B TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFIX TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
PHF19 TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
NOP56 RPS8 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
KMT2A UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CSNK2A2 RNF2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CDC5L SENP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20467437 33961781 26511642
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
PELP1 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33742100 11481323
PHF20 MCRS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
SENP3 RRP1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20926688 33961781 26511642
TAF4 SP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11988536 9742090
TAF6 TAF9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23292512 7597030
KAT8 HCFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16227571 20479123 24981860
KAT8 PHF20 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20479123 33961781 24981860
LAS1L WDR18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22190735 33961781 26344197 24981860
LAS1L TEX10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22190735 22939629 26344197
LAS1L NOL9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22190735 33961781 26344197 24981860
NPM TEX10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
MDM2 NPM1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SPRTN UBC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF7IP SP1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT8 TP53 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 NPM â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 18259216 9642267
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
MDN1 TEX10 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
NOP56 RPS4X â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ESR1 ASH2L â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
SENP3 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19680224 15632193 22684029
MEF2D EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11096067 10825153 10933397
UBC MDM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17290220 19166840 18566590 19098711
HCFC1 MEN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
SUMO2 PARP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19471022 21693764 32786267 25027693 21252943 19779455
ESR1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
HCFC1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31076518 23508102 33961781 20305087 24981860 22939629 15199122
TAF4 TAF7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14580349 29111974 22939629 26344197
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
PELP1 SUMO2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19471022 21326211 19394292 32786267 21252943 16169070 21693764
ASH2L HCFC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CDC5L WDR18 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20467437 22939629
CDC5L CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20467437 21145461
MDM2 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20708156 24804778
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
MEN1 RBBP5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 17050672 14992727 15199122
KAT8 RBBP5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15960975 24981860
CUL3 DHX15 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26949739
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
ESR1 DNM1L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19805454 21217774
CEP19 SENP3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
ATF7IP SUMO2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CHD8 WDR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ASH2L CHD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
WDR5 MCRS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 24981860 27705803
MDM2 NPM â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33495326 15144954 24583282 31406141 23039052 22510990
CHD8 RBBP5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
WDR5 PDPK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 27705803
WDR5 E2F6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 28514442 27705803 33961781 24981860 26186194
WDR5 PHF20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 24981860 27705803
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
NOP56 NPM â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 12777385 33961781 26496610
SENP3 SUMO2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19394292 25027693 16608850 11029585
WDR18 PELP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8149485 21326211
PELP1 NOL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22190735 33961781 24981860 26344197
PELP1 MDN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21326211 22939629
PELP1 LAS1L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21326211 20442285 22190735 24981860 22939629 26344197
TEX10 WDR18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21326211 33961781 26186194 26344197
TEX10 NOL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197
WDR18 NOL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
PRPF31 RUVBL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LAS1L PELP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PELP1 WDR18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SENP3 WDR18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NOL9 PELP1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PELP1 SENP3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MCRS1 PHF20 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
LAS1L TEX10 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PELP1 TEX10 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
CDK4 CDK6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 28205554 28628118 33961781
WDR5 KANSL1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
BOP1 NOP56 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 22939629
PELP1 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14963108 21182205 11481323
ESR2 PELP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21182203 12415108
TEX10 PELP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21326211 22190735 33961781 24981860 26344197
NPM PELP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21326211 33961781 26186194
SENP3 TEX10 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21326211 33961781 26344197
SENP3 WDR18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21326211 33961781 26186194 26344197
E2F6 RNF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MEN1 ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23508102 24981860 17050672 14992727 15199122
CDK4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
TAF1 MDM2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9388200 17237821 16713569
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MEN1 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 27705803 23508102 24981860 14992727 15199122
WDR5 KAT8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 20479123 24981860 27705803
SUMO2 DAXX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17081986 19471022 19394292 32786267 16475184 28851805 21252943 22578841 21693764 21383010
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
NPM SENP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21326211 18259216 33961781
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
DAXX TP53 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
HIF1A UBC â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
NOL9 WDR18 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ASH2L WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31544921 17925232 16253997 20305087 21285357 15960975 21531708 15199122 17178841 25666610 16892064 15960974 18066051 23870121 23508102 21884981 32076268 33022573 22939629 16878130 31076518 27705803 19556245 17500065 19131338 33961781 24981860 16603732 26186194
ASH2L HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31076518 23870121 23508102 33961781 20305087 24981860 12670868 15199122
ASH2L RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 31544921 17925232 12482968 16253997 21124902 20305087 21516116 21285357 32296183 21220120 15199122 17178841 16892064 15960974 23870121 23508102 26886794 16878130 31076518 17500065 19556245 19131338 33961781 24981860 16603732 23414517 34079125
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 MEF2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10825153 11796223 11096067
MCRS1 DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22609355 11948183 32296183
HIF1A MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12606552 10640274 25447306 15880652 19696166 25535359 17234751 15385570
TAF1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 10891494
TAF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 16713569
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RRP1B PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 20926688 19710015
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
RRP1B NPM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20926688 33961781 19710015
TAF4 TAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 22939629 14580349 31753913 11564872 26344197
TAF7 TAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 22939629 16713569 7824954 31753913 11592977 18391197 14580349
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 CDCA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
KAT8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17189187 16601686
SP1 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12840223 11297539
HCFC1 WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 27705803 24981860 20305087 22939629 12670868 15199122
WDR5 CHD8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 20085832 24705355 18378692
NR1H2 VIM â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LRRK2 DNM1L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22228096 22639965 24282027 29541021 23813973
HCFC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12670868 10976766
ESR2 MEF2D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 PELP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19605405 15087130
SENP3 PELP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21326211 20442285 22190735 33961781 24981860 26344197
PELP1 WDR18 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21326211 22190735 33961781 24981860 26186194 30021884 26344197
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
KANSL1 KAT8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KANSL1 PHF20 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BOP1 NOP56 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
NOP56 RPS11 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ASH2L UBC â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
RBBP5 UBC â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
TAF6 TAF7 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 14580349 29111974 22939629
UBC WDR5 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HIF1AN HIF1A â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 6802010 19071119
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CDK4 CDKN2A â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
INO80C RUVBL1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
KAT8 WDR5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
DAXX MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405218 18566590 18583933 16845383 15364927 20195357 28875283 23038753 21134643
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
CDK6 CDKN2A â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
LAS1L NOL9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CDC5L DHX15 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
RBBP5 WDR5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 31544921 17925232 16253997 20305087 15960975 30089852 21531708 21220120 15199122 17178841 25666610 31685992 15960974 27320920 23508102 21884981 32076268 33022573 16878130 28813667 17041588 31076518 17500065 19556245 27705803 24981860 33961781 16603732 26186194 31400120
TAF6 TAF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 29111974 22939629 7667268 31753913 12453419 14580349 26344197
TEX10 WDR18 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
KANSL1 WDR5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPLP0 RPS18 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
HIF1A HIF1AN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS11 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP0 RPS8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP0 RPS4X â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP0 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS18 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS4X RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
SP1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10649433 22025288 15067344 17370299 21830402 17225865 12134028 19115249 16239970
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
CDKN2A CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17881001 26186194 23602568 9751050 11739795 11556834 9380698 15232106 16713569 17955473 10491434 16915296 17909018
CDKN2A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 17145710 11900540 23602568 9529249 11556834 16161044 17881001 17517622 15065884 9228064 15232106 26496610 10585280 17909018 26186194 17353931 10580009 17955473 10491434 12529334 10719365 28042499 8259215 24855949 8891723 23455922
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
SENP3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15632193 19680224
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
TP53 HIC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19649206 19491197 16301995 17079468
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
SP1 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21611785 22890831 22125028 20963645
TP53 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21611785 11713584 10365096 15217513 16258956 14675138
NPM1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
TAF1 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28673515 15053879 20124405 16713569 29556568 24289924
TAF4 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF4 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF6 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SP1 TAF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12364593 11340078
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
DAXX TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12954772 21482821 21134643 16845383 25241761 15364927 16713569 12482984 15339933 23038753
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
HIF1AN HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11641274 12042299 12080085 12215170 22841746
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
HIF1A HIF1AN â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 6.0 1.0 Reactome 12615973 11823643 14701857 12042299 12080085 15239670
HIF1AN HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 12573436 11641274 14734545 12042299 12215170 12446723 17244529 19071119 17003112 12080085 19696166 16189514 19940151 24145445 26751287 12432100 26972000 17382325 19074848 26752685
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7553870 9060426 2674689 24669866
SP1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19733223 17409431 11872750
CDK4 PELP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20807815
KMT2A KAT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15960975
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
KMT2D ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16603732
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
SENP3 SUMO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19394292 11029585