Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FGFR3 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
PPP1CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
MYC FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC NOP56 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
H3C14 NOP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 CEBPZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12534345 5216050
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10529175 9724739
TP53 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416861 10082513
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 SCN3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
PPIB NOC2L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
ILK PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313365
ILK HIF1AN â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 17003112 0606877103
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
RPL18 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS6 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HNRNPU MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EED H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3C2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3-3B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
MAP3K14 GRWD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LRIF1 NOC2L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RRP8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RRP8 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RRP8 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NOP2 RRP1B â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
NOP56 RPS14 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
DOT1L NPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20431927 26496610
PDGFB MDM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAK16 MDM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MYC FBRL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC PESC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC SYK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
RBM34 NOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 NOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25665578 31665637
SRPK3 NOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 23602568
EED NOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 26496610
NOP2 RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
NOP2 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
RL18A RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 20926688
PESC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25825154 20926688
MAGBA RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MECP2 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RRP1B NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
RRP1B MK67I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
PDGFB NSA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PDGFB CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PDGFB NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PDGFB RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ILK FBRL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 23455922
FGF3 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGF3 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NOP56 RL18A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12777385 22939629
NOP56 MK67I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
ESR1 NPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 33731348 21182205 20348541
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
EED NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 26496610
MAK16 NSA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 NSA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
NSA2 RL18A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 MAK16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
MAK16 RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAK16 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAK16 RBM34 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAK16 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RRP8 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18A CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MECP2 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGF8 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN512 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAGBA CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 CEBPZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
RS6 GRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29991511 29568061
GRWD1 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29991511 26344197
RRP8 RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MECP2 RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
RBM34 RPF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGF8 SRPK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RS14 SRPK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RS6 SRPK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
MECP2 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAGBA NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CPNE2 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RRP8 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN512 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGF8 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RS14 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SCN3B NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PKHO1 NOC2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NOC2L MK67I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
MECP2 RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MECP2 RL18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 MK67I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
MK67I PESC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26186194
FBRL RS14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 29568061
FBRL RS6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 29568061
FBRL RL18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 29568061
NPM RL18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
FGF8 RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18 RBM34 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18 RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18 ZN512 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18A RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RL18A RBM34 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RBM34 RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN512 RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GTPBP4 RRP1B â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
EED HIST4H4 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
SRPK2 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
SRPK1 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
FBRL RRP1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 20926688 29568061
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
NPM MAK16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NPM RPF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NPM NOC2L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RS6 NOC2L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 33961781 29568061
IF16 NOC2L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25693804 25665578 31665637
FBRL MK67I â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 22939629 29568061 26344197
MK67I NPM â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 33961781 26186194
MK67I RL18A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
NPM RBM34 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NPM RRP8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RL18 RS6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 29568061 26344197
RL18A RS6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 29568061 26344197
RS6 RRP8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 33961781 29568061
RS6 RBM34 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 33961781 29568061
IF16 RBM34 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25693804 25665578 31665637
IF16 PESC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25693804 25665578 31665637
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
PPP1CA RRP1B â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NOC2L PES1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MDM2 PPIB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24583282 29876924
NPM NOP2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 26186194 8089149
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
SRPK3 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
P53 AURKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29340707 20959462
ESR1 GRWD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
SRPK3 RBM34 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
DOT1L HIST4H4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GTPBP4 MAK16 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
NOC2L NSA2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST2H2AA3 HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NOC2L NOP2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CEBPZ PES1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
ESR1 RS14 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 19805454 25604459
GTPBP4 NOC2L â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NOP56 RPS6 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NOP2 NSA2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PES1 RRP1B â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
NOP2 NOP56 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
NIFK NOC2L â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
NPM RS14 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
AURKB HIST3H3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
MDM2 NPM â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33495326 15144954 24583282 31406141 23039052 22510990
SRPK2 NOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 26344197 23602568
MK67I NOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 22939629 26186194 26344197
NOP2 RS6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 22939629 33961781 29568061
NOP2 RL18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781
NOP2 RL18A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
NOP56 NPM â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 12777385 33961781 26496610
NOP56 RL18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 12777385 22939629
NSA2 RPF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 26344197
MK67I RPF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 26344197
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
RL18A NOC2L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197
MK67I RS6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 22939629 33961781 29568061
MK67I RBM34 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125
MK67I RRP8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 34079125 26186194
RS14 RS6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 29568061 22939629 26344197
NPM FBRL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26496610
RL18A RL18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 26344197
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
PESC NOP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25825154 26344197
CEBPZ NOP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
NOP2 NSA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
RRP1B RS6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 20926688 33961781 29568061
NPM AURKB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24857377 31586073
ILK AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12149249 9736715 12176337 11445557 18339839 11825911 11313365 14500673 11278835 11546794
FGF8 FGFR3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10574949 22244757
NOP56 RBM34 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
NOP56 PESC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
NSA2 RBM34 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
MAK16 RRP8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
RS14 CEBPZ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
RL18 CEBPZ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
NOC2L CEBPZ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
RBM34 CEBPZ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
P53 SRPK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32807901 21130767
SRPK1 SRPK3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23602568
RBM34 NOC2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
FBRL NOC2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
PESC NOC2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25825154 26344197
NOC2L P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16322561 20959462
PESC FBRL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29568061 26344197
HIST3H3 HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
NOP2 RPF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NIFK RPL18 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK7 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 9315650 9372954 9840937
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MYC NOP56 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 17314511 30415952 29467282
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
NOP56 RS6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 22939629 29568061 26496610
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
CEBPZ P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12534345 16713569
NOP2 RPL18A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
GRWD1 NOC2L â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CPNE2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MPG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17129768 14761960
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC RPS6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RPS6KA6 CEBPZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RRP1B NPM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20926688 33961781 19710015
PDGFB GRB7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8940081 10508235 9739761
JAK1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10825200
PDPK1 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9368760 11825911 14500673 10698680 31467278 12149249 27563096 11313365 11278835 22569334 26264872 10226025 32876514 26256536 21775285 11438723 11445557 23397142
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
NPM P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15144954 23443559 16740634 31152661 12080348 15082766 16376884 15964625 15310764 32807901
P53 IF16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11146555 30193098 21397192
NPM RS6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 30021884 34079125 22939629 29568061
NOP2 FBRL â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 34079125 9654073 29568061 26344197
NIFK PES1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
NOC2L RPF2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
GTPBP4 RPL18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
NIFK RPL18A â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
GTPBP4 RPL18A â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NOP2 PES1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
NOP56 CEBPZ â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 26496610
NOP56 NOC2L â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 26496610
AKT1 PDPK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
GTPBP4 NIFK â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
AKT1 MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32450252 25241761 18332867 12145204 19166854 15527798 20856200 11715018 23397142 11504915 11923280 21930127
NOP2 NOP56 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 34079125 22939629 26344197 26496610
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
P53 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19303885 25417702 34408321 17268548 23252402 23880345 22807444 15094782 20962272 12529318 21726810 22124327 18981217 16173922 23318437 15558054 22524527 30584071 31626714 22301280 32516735 20174603 22912717 21075307 15848166 18566590 23483203 26882543 23402884 14671306 15001357 10889512 17908790 19411846 10640350 21561866 14499615 33503543 21986495 24998844 15908921 26673821 17098746 25362358 32066565 25739118 29295817 34362424 16595680 20591429 27336364 22745160 24462112 32427887 18467333 26578655 23261415 9271120 16055726 19357310 31591476 23169665 16338390 10608892 30464405 15542844 12612087 22266868 15550400 22331460 22914926 19071110 7686617 14559824 20959462 19941302 14596917 25512388 27129163 19597489 25609649 32904724 11351297 29121928 22487680 11709713 24127580 10562557 15358376 21584881 25312347 27826076 19098711 24980433 24413661 21887275 17116689 14612427 30948704 26001071 19857530 33061576 31138778 23802716 20234175 25313037 21988832 17616658 11744695 17666403 22525275 12897156 25156994 33020477 11925449 16152627 29876924 30244831 1614537 17363365 22474335 11112690 23443559 17297477 27905468 19085961 20479273 31940492 21261729 14517261 26908445 16866370 27893708 22653443 17470788 10488081 23370271 19223463 16751805 26556313 10734067 19411066 11223036 27856536 14704432 20124408 24240685 24842904 32901886 22948151 19234109 35140242 21084285 32894144 17848574 22737255 10561590 25168242 10435614 11697899 25543083 21572037 22920093 18604177 32874188 22659184 17591690 16845383 22444248 31239268 25283148 26186194 24200963 23826318 7689721 20047188 24314634 12167711 15308643 17318220 21857681 11431470 18815136 15950904 20705607 17525743 26876197 31177307 9529249 22374672 12915590 33650658 10601022 20837658 18223694 30097011 28205554 32334023 15247280 23776465 21268072 27308622 11713288 18234963 9582019 18784078 29487367 23776060 11713287 20484049 26720344 9131587 30109812 33961781 24361594 32807901 31066983 15824742 11562347 21454483 22157679 21088494 11070080 22575647 22083959 26540344 15210108 18332869 32528731 18172499 11094089 21132010 16414131 10827196 27031960 10892746 15280377 16023600 18665269 10202144 15058298 29549180 16212962 16905769 11278372 20657550 9809062 15295102 26238070 22391559 18061646 17310983 18485870 9278461 21925390 20659896 9824166 23150668 25637791 30598450 19160491 28605833 12690203 22467867 31594538 11572869 11384992 11486026 27807478 17936559 30679555 16678796 30252118 31652301 15144954 22411991 22084066 30175854 21478269 27543608 16624812 17290220 32097779 17301054 20694676 11714701 24667498 20395212 16547496 12381304 8058315 22266850 29755129 22085928 17159902 10196247 21316347 27886165 27215386 25384516 7926727 16964247 19081178 32198344 11046142 28549433 26350565 31533005 12867035 10321734 19590512 22991965 25277184 24207125 18541670 19166840 25103245 30320919 26883110 20235143 17139261 11597128 21071676 19568783 18813780 19805293 17056014 17989425 21317885 17234751 20588255 21170087 10347217 11839577 25954860 21060154 24926618 21750659 16331255 29269425 27811966 19305137 24659749 9450543 23201157 30879903 16870621 28362432 21149449 20570896 23609977 33765973 27106262 33355139 34040386 22588298 22389628 19033382 18264029 27462439 31092600 12208736 17369817 28082682 16579792 23246961 20708156 15013777 21465263 28542145 23572512 19483087 31665549 22975381 17438265 15604276 11178989 24488098 16432196 22227409 28628118 30005830 20639885 20847049 9363941 31406141 19816404 26475964 29899406 16861890 30320499 20660730 19332559 14702041 11284721 18316739 19837670 25464845 12426395 10681559 17302414 16107876 22510990 15154850 21098709 19106616 10722742 19188367 22366412 29524278 21084564 23134341 25624478 30455251 20173098 12620407 9223638 16713569 17426254 31647545 10766163 30454706 21471462 24621507 23652204 19153082 8875929 31152661 18309296 31968249 31796886 15122315 30532073 10980696 17080083 15064742 11285227 29547122 21965653 33495326 23728348 15242646 17347673 12842086 12944468 19255450 23671280 22916255 17875722 30355102 14741215 23946421 20591651 15053879 28514442 25241761 24567357 16215989 19656744 30832340 22262183 27249653 26203195 16857591 15313915 15933712 28223335 20542919 12552135 24643130 27282385 20080206 28553961 22819825 33579943 16159876 9724739 17380154 22318540 29997244 29670376 22103682 22032989 28394340 31903119
NIFK NOP2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
GTPBP4 NOP2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GTPBP4 RPF2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NSA2 PES1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NIFK NSA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
PES1 RPF2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CEBPZ NOC2L â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GTPBP4 PES1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
FBRL NOP56 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 26496610 17636026 33961781 26186194 34079125 22939629 29568061 26344197
GTPBP4 NSA2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NIFK RPF2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NSA2 RPF2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL18A RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS14 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18 RPL18A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDKN1A CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
EIF2AK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17451862 16083285 1088347 10082513 10348343 10884347 16552184 9315650 9737981 19413330 16713569 10747897
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
PRKCZ JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15526032
AURKB BUB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 28137420 19007248 10464286 16179389 12082625 16222244 15130946 11350965 14722118 16185088 14583461 12789343 15537652 15681610 12588998 15851689 17924679 15684425 12560483 10469656 11856369
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
PDPK1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11687500 11747822 12670391 15802604 17680028 18802401 19109239 19122654
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8131746 8394352 15175348 15466476 94178255 7731720 7624324 8157000 8039496 8621729
PDPK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 156.0 1.0 Omnipath 15505410 12538620 12176337 19951971 24352480 11752451 19401591 11369519 10698680 10601311 15718470 24950409 20481595 24169049 10570282 16798838 14993273 11500365 9368760 19844585 17680028 7637810 9169478 26256536 7722458 9094314 12750173 11438723 18802401 9252186 23331499 18456494 9104825 10592173 16189514 20361045 18988627 11278835 20163786 20333297 20041157 12808134 19602588 8630736 10207050 11241670 10438924 9868760 25912234 20153221 25582703 11445557 21775285 12149249 14666721 18596232 9512493 23397142 11809791 12167717 21798082 16033886 10679787 16787925 29562639 15550174 21071413 8978681 10833263 19203586 10226025 26937223 14500673 20161206 11136732 11825911 11042193 9642236 22569334 18662999 9736715 12242303 11313365 11598012 11134526
PDPK1 PRKCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10764742 16189514 27554858
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 SRPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19592491
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 12529330