Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 MTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23552838 22286760
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
ZHX1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZHX1 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CRYZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
NFKB1 AGER â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18622638 19616578
RELA AGER â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18622638 19616578
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
HNRNPC AUTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MDM2 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17347673 5219751
TP53 BHLHE40 â—¼   COLOCALIZATION 2.0 0.8 intact 17347673 5219751
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
PTPN1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
IRS1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003536
FXR2 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TP53 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160719 20074560
CSNK2A2 CCAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24962073
HNRNPC CDC5L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CDC5L NKAP â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PICK1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PRMT1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SNX6 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
COIL FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
COPS6 PTEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
KLF1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1017029108 21670263
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 PTEN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
CSNK2A2 NOL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12191471
CSNK2A2 SET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23374587
CSNK2A2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938077
HDAC6 CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 8295686 21847094
PRMT1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DAXX TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 14557665 5216762
NKAP DDX41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
TP53 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416861 10082513
HSPB1 EIF3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FXR2 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 PAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
FXR2 ZMYND8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 PICK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMC3 GPATCH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GTF3C3 POLR2E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HADHA KIF1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HSF1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19793920
HDAC1 KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15542849 11287616
HSF1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19793920
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
PIN1 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 HNRNPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18296503 21317560
TP53 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8200620 21821029
HNRNPK PRMT1 â—¼   METHYLATION ✅ 2.0 0.8 intact 6803829 19101556
SAP18 HPS5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
SIRT1 HSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23349863 19229036
NR1D2 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPB1 ZNF670 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KDM1A IL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PTPN1 IRS1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6732079 11579209
RELA KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19208907 23423566
NKX3-1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20530667 12173040
MDM2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 23839035
MYCN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20145147
SMC4 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
NCL NRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 NFATC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
NOL3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0710017104 18087040
SLBP NXF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23804756 2017161
PAF1 POLR2E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PBK PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24012691
SENP3 PELP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21326211 8149485
PTEN PICK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
POLR2E RTF1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RELA PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14729949
SAT1 RBM17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SAP30BP RBM17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RNF113A SRRM1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TAF1B SET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17318177 5219672
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
RBM17 SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
LAS1L NOL9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RNPS1 SRRM1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
GTPBP4 PES1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPC PAF1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPK SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HDAC3 KDM1A â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
SAP18 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9150135 16189514
HNRNPC RBM17 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PRPF4 SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NIFK PES1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CUL4A DCAF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31155351 21145461
CUL4A NFKB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30945288 21145461
CUL4A WDR61 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
ARRB2 RTF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JPH4 BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CBX4 PCGF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
RNPS1 CCNL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 17353931
SRRM2 CDC5L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
DDX41 SRRM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 25920683
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYCN HDAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20697349 31856871
LPIN3 HDAC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JPH4 UBE2O â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAK16 MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NKTR RNPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 14729963
NOL9 SENP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NXF1 SURF6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
EIF3D EIF3H â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
BCLAF1 PNN â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SRRM2 ZC3H18 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
PNN THRAP3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPC PNN â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CSNK2A2 RNF2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CSNK2A2 PPP1R8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
EIF3A EIF3H â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DPF3 BCL7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KDM1A NMI â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 23455924 21516116
HDAC2 EMSY â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26841866 23752268 24981860
HDAC1 EMSY â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 26841866 23752268 28514442
PCGF3 AUTS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22325352 27705803 25519132
TULP3 BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
CASQ2 DAXX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PCGF3 CBX4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 22325352 27705803
CDC5L SENP3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26511642 20467437
DCAF7 PCGF5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 27705803
DPY30 MEN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
HSPB1 HSF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25036637 19597476
GTPBP4 SURF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
MDM2 NCL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NMI MYCN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9781816 8668343 10597290
IRAK1 CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15647277 32707033
GTPBP4 MAK16 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
BCLAF1 THRAP3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF3H EIF3L â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
MTA1 TP53 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RNF113A SRRM2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
EIF3J EIF3L â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MTA1 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6613464 18451879
DAXX HSF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15016915 20620219
RNF2 PCGF5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
CTDP1 POLR2E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MED6 POLR2E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BCL7B DPF3 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
EIF3A EIF3L â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CDC5L DDX41 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25920683 20467437
MEN1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17050672 24981860 14992727 23508102 15199122
LAS1L PELP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CBX4 RNF2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CREBBP MDM2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
GATAD2B ZNF219 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
KDM1A MBD3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21937684 23455924 19703393
GATAD2B MTA1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AUTS2 PCGF5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KDM1A CDC5L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17043677 31413325 20467437
HSPB1 DAXX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15911090 25241761 11193028 31615977 11003656
DAXX HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10669754 12140263
DCAF7 PCGF3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24981860 27705803
EIF3F EIF3A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 24396066
GTF3C1 GTF3C3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PELP1 LAS1L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 26344197 21326211 20442285 22190735 22939629
LAS1L PELP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RNPS1 NKAP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 17353931
PELP1 NOL9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 22190735 28514442
SMC3 PDS5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17349791 26344197 31010829 19906707 15855230 21111234 17113138
TAF1B TAF1D â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TAF1C TAF1D â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
NOL9 PELP1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF3C1 GTF3C5 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PELP1 SENP3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC3 RELA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CSNK2A2 PCGF5 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPC SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
GATAD2B HDAC1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
EIF3A EIF3D â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
KDM1A MTA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21670149 19703393 26028330
GATAD2B HDAC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SAP18 RNPS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16537548 26344197 22388736 12665594
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TAF1B TAF1C â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EIF3D EIF3L â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
GTF3C1 GTF3C3 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EIF3D EIF3J â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RNPS1 SAP18 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PCGF5 AUTS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25519132 26186194 27705803 28514442 22325352
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
RNPS1 DDX41 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 25920683 17353931
HUS1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10846170 16189514
RNPS1 SRRM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 26344197 17353931
NKAP SRRM2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DAXX TP53 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
GTF2A1 POLR2E â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EIF3F EIF3J â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MYF5 PIN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NCAPG SMC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
PNN RNPS1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
NCAPD2 SMC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 17827154 24048479 26344197 21258344 16428440 12354758 28514442 27068747 19041848 10444591 25123934 12124384 23752268
MBD3 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25123934 24981860 20388487 26344197 21258344 22939629 12354758 23752268 17827154 26949739 19041848
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 34026424 24981860 16511565 22939629 26496610 9885572 27098840 26344197 21258344 10840944 14722073 26028330 12920132 33264408 17922035 28514442 16189514 26949739 18451879 11146623 23752268 20585571 29997244
BID ZHX1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18544533 21389118 21081496 33649538 32828283 17984062 32450252 12538596 21988832 15878855 26545496 12488444 21466165 11588219
CDC37 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HDAC3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16528103 18241676
CREBBP KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11259590 21670263
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
EIF2AK2 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30071259 20685959 28779021
EIF3J EIF3A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14519125 9822659 23623729 18599441
EIF3L EIF3D â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22190034 24981860 26344197 22939629 18599441 22863883 28514442 11590142 23623729
MYCN GRIN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
GTF2A1 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14631847 28539435 14675539
NKX3-1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16697957
KDM1A HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21937684 34031383 21670149 19703393 24981860 16079794 26344197 21258344 20164337 9804427 32882276 12493763 11102443 12032298 23752268 28667074 26949739 34050636
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MAPK8 ZNF219 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NFKB1 MEN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11526476 16713569 16651450
SENP3 PELP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26344197 21326211 20442285 22190735
RELA PIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19458071 19668231 16950761
TAF1D TAF1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17318177 19615732 26186194 28514442
TAF1D TAF1C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17318177 19615732 26186194 28514442
GATAD2B MBD3 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NIFK PES1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PCGF3 RNF2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PCGF5 RNF2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EIF3H EIF3J â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CBX2 RNF2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
NIFK SDAD1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
RBM17 SAT1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
SRRM1 SRRM2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MBD3 MTA1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
HADHA HADHB â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
NCAPD2 NCAPG â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
PNN SAP18 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
HDAC2 MTA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CDC5L RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTPBP4 NIFK â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTPBP4 SDAD1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
EIF3F EIF3D â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 22190034 31527668 26344197 24981860 19615732 22939629 26186194 28514442 23623729
EIF3H EIF3D â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 22190034 24981860 26344197 19615732 22939629 32269044 26186194 28514442 22863883 23623729
EIF3H EIF3F â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 31527668 24981860 26344197 19615732 22939629 19748344 18599441 32269044 26186194 28514442 23623729
TAF1C TAF1B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17318177 26186194 16713569 28514442 7801123
CDC5L SRRM2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PAF1 WDR61 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HDAC2 MBD3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PDS5A SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
NCAPD2 NCAPG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CDC5L SRRM1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GTPBP4 PES1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
LAS1L NOL9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EIF3D EIF3L â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
POLR1A POLR1C â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NCAPD2 SMC4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 NCAPH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POLR1A POLR2E â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POLR1C POLR2E â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GTF3C3 GTF3C5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPH SMC4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3A EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3F EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3H EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG SMC4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG NCAPH â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HADHA HADHB â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAF1 RTF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3A EIF3J â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3A EIF3D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3F EIF3H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TP53 MGMT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17564708 19846904 19056673 9780001 18555750 8616846 21957016 17234766 12503076 20525765 19531487
NMI SOX10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16214168 17145710
CSNK2A2 AQP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11742978
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
PTPN1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9566916
RELA BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22967044 20018891
TP53 BHLHE40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22723347 17347673
TP53 BID â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12402042 16151013 18574470
MAPK8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18594987 25326334 25077544 27374471
TP53 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15240700 12402042 18431400 15024076
CSNK2A2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11583622
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
PTPN1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16388599 12176037 16189514
CCAR2 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18235502 22735644 18235501 33459133
CSNK2A2 CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20068231 15082798 19413330 12930845
CDK11A EIF3F â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12446680 19245811
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
DVL1 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2A2 HSPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10772927 12558502
CSNK2A2 GTF2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 11278496 18452278
CSNK2A2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17444818 19662498 15987703 16107342 11035045 12077256 11707428 12297295
CSNK2A2 PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17570479 2557337
CSNK2A2 EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 11146653 12588975 18212344 9806882
CSNK2A2 PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10066810 15302935
CSNK2A2 SPIB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17570479 10618498
CSNK2A2 EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11500362 18669648
CSNK2A2 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19651622 19415658 12082111 16565220 19007248 19691289 18669648 20166139 18691976 17081983 20230923 20068231 18452278 17570479 17287340 19413330 18510355 18212344
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 PPP1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18669648 18767875 18088087 20068231 8288648 17287340 18491316 18212344 15302935
CSNK2A2 UBE2R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12037680 18669648
CSNK2A2 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18088087 12769847
CSNK2A2 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
CSNK2A2 MYF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9461343
CSNK2A2 GTF2A1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12107178
CSNK2A2 KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9722526
CSNK2A2 PPP1R8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9407077
CSNK2A2 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12659875 15302935
CSNK2A2 IL16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12450396
CSNK2A2 NKX3-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16581776 23129228
CSNK2A2 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18971944 28416484 20507565 19118383 21576760 18583988 15066279 20471329 18452278 25477519 21592330 15367657 21118972 20533398
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
CSNK2A2 CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 12591939 19664994 19664995 18669648 15302935
MEN1 CTNNA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
PTPN1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27824079 18515860 18387954
HDAC6 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21220424 21847094 17643370
DAXX HSPB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11003656 11274345 16406523 20452955
HSPB1 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 25241761 11003656 11193028 15911090
DAXX TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12954772 21482821 21134643 16845383 25241761 15364927 16713569 12482984 15339933 23038753
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
EIF2AK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17451862 16083285 1088347 10082513 10348343 10884347 16552184 9315650 9737981 19413330 16713569 10747897
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
SOX10 HDAC2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 26423937 12198163 10856243 21423190 21653862 17699610 22814607 18803322
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11533489 16189514 12419806
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
MAPK8 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11259409 11231586
MDM2 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19249676 16360036 23092970
HNRNPK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18472002 16360036 23092970
HNRNPK MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19249676 16360036 23092970
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413
MAPK8 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19651622 17081983 10747973 20166139 18767875 20068231 18669648
NFKB1 HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17724475 21725609 23178297 23572150
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
MAPK8 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15001544 18728222 26882989 12409308 10592173 15314024 12417588 15613682 14579029 10722755 26538579 29207597 15199052 12351658 16055440 11606564 12510059 15212693
PTPN1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 21071413 11579209 10660596 10592173 18988627 10751417
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
MAPK8 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16648474 10978313 17875713 27893713 11274345
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 29578371 17081983 19007248 23434668 21540183 22622703 17924679 18187866 24296261 18838864 19413330 20027304 21471201 19107194 16964243 18669648 15302935
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYCN MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15917661 15644444 15927364 19649205
NCL MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24147044 16751805 22103682 20195357
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MEN1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11526476 14508515 16713569
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
MYCN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20811720 11107122 10050884 21862876 20145147 19885598
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
NKX3-1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22266868 11395510 11375890 17202838 19242108
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20617556 15152190 24064732
SIRT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19408108 25217963 15152190 21081649
SIRT6 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 19135889
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
TP53 HADHB â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368