Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
POLA1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
PRIM2 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
PRIM2 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
E2F1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15033491
NCAPD2 CNN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
XRCC1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15367657 5217189
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 RRP1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20040599
E2F1 RRM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416980
MAPK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14967450 22802261
E2F1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18348985
E2F1 NCAPD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 16144839
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
E2F2 NCAPD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 16144839
E2F3 RRM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1501447 10733529
E2F3 NCAPD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 16144839
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
MAPK3 XPO5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 27846390
SMC2 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
SMC4 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
POLA1 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
SMC4 SMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
AURKB NDC80 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 20471944
BMP1 SMC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DPEP1 SMC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 SMC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26166704 31527615
POLA1 PRIM1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
E2F1 E2F3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
ESR1 RRP1B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
NEK6 NEK7 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ESR1 AKAP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33731348 31527615 21182205
NDC80 NUF2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
POLA1 PRIM2 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PRIM1 PRIM2 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NCAPD2 SMC2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
NCAPG SMC2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PARP1 E2F1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20133863 14627987
NCAPG SMC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
NCAPD2 SMC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
E2F1 XRCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19031698 18348985
E2F1 POLA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18347061 7929342
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15014447 11491305
E2F3 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12748276 15574595 18319725
SHC1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
ESR1 NEK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
RRP1B PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19710015 20926688 34079125
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
SMC2 SMC4 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
CKAP5 NDC80 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
NCAPD2 NCAPG â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
NCAPD2 NCAPG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NCAPD2 SMC4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 NCAPH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NDC80 NUF2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 SMC2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPH SMC4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPG SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG SMC4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG NCAPH â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPH SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PRIM1 PRIM2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMC2 SMC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
AURKB NDC80 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23569217 20471944 14602875
E2F3 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
E2F2 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725
E2F1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15510213 7575488 18590585 17303408 18319725 17660363 15279786
CDK1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17218262 17303408 17660363 18414028 18590585 7575488
E2F1 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 7623816 14618416 12760745 11799067 8137237 12629169 17108174
E2F2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725
E2F3 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15510213 10733529 18319725
CDK1 RRM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20058876 17924679 18669648 18767875 9990288 22632967 17693683 19413330 16964243 19664995 19415658
CDK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7592773 30392930 18691976 19387552 20068231 96029687 16371510 1400350 19941816
CDK1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7575488 18590585 17303408 8087847 27175585 17570479 17660363 15279786
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18971944 20507565 19118383 21576760 18583988 15066279 20471329 18452278 21592330 15367657 21118972 20533398
CSNK2A1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15822905 17081983 16565220 18088087 29854279 2492519 34359868 25995454 1956339 16094384 15581363 18591256 16964243 92065884 15302935
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2A2 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18971944 28416484 20507565 19118383 21576760 18583988 15066279 20471329 18452278 25477519 21592330 15367657 21118972 20533398
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
PARP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14627987 20133863
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
KSR1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 8248196
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
PARP1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9563011 9518481
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368