Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F4 CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
SPTAN1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMC2 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMC4 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CANX IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
SMC2 NCAPH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
XRCC1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15367657 5217189
LRRK2 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
E2F4 SMC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 SMC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
E2F4 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15033491
SMC4 VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SPTAN1 SMC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMC4 SMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
SMC2 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
SMC4 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
SMC4 MGAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HDAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
LRRK2 ABCE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
CDK9 SMC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22863883
CDK9 SMC4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22863883
ESR1 CND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26166704 31527615
ESR1 SMC4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26166704 31527615
ESR1 CNDD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26166704 31527615
MIPT3 SMC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
SSA27 SMC4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 33961781
SMC4 MIPT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RYBP CSNK2A2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
MCPH1 TERF2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
MYC SMC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC SMC4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 17314511 29467282 17353931
E2F4 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23060449 9858615 9724731 21102443
SMC2 CNDD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26166704 17268547 14532007 26496610
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CSNK2A2 RYBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
MAP1B LRRK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24754922 21159966
NCAPD3 SMC4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SMC2 CNDH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17268547 14532007 26166704 33961781
CNDD3 SMC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29028794 14532007 26496610
CND3 SMC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14532007 26166704 22863883 24981860 11136719 22939629 26344197
SMC4 CNDH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17268547 14532007 26166704 33961781
CNDH2 CNDD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17268547 14532007 26496610 26166704 33961781 26344197
CHEK2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 26799419 19375317
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
XRCC1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15555565 9584196 18971944 24778456 15044383 34111398 14500814 30260704 20302655 12897160 34079125 20303835
E2F4 SMARCA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11799066
E2F4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 12789259 20946668
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NCAPD3 NCAPG2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SMC2 CND3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 17268547 14532007 26166704 22863883 24981860 11136719 22939629 26344197
SMC4 CND1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 10958694 22863883 22939629 26344197
CND1 CND3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 17268547 14532007 26166704 22863883 24981860 11136719 22939629 26344197
NCAPH2 SMC4 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
NCAPG2 NCAPH2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
NCAPD3 SMC2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SMC2 CND1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17268547 14532007 10958694 26166704 22863883 22939629 26344197
SMC2 CND2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17268547 14532007 26496610 26166704 22863883 26344197 22939629 21633354
SMC4 CND2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17268547 26496610 26166704 22863883 24981860 22939629 26344197
CND2 CND3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17268547 14532007 26496610 26166704 22863883 24981860 11136719 22939629 26344197
CND2 CND1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17268547 26496610 26166704 22863883 26344197
NCAPH2 SMC2 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
TERF2IP TERF2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8286516 21829167
NCAPD3 NCAPH2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
NCAPD2 NCAPG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
TERF2 TERF2IP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SMC2 SMC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 22939629 17268547 14532007 26166704 22863883 26344197 30021884 9789013 17113138
NCAPD2 NCAPH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 SMC4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 SMC2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPH SMC4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPG SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPH SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG NCAPH â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG SMC4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SMC2 SMC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CHEK2 XRCC1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11438669 15459660 15810020 15867354 17296736 17464182 17568790 18048416 18566216 18756267 18931676 18971944 19686080 19788416 20019063 20126263
CHEK2 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18566216 18971944 17464182 15810020 24947324 20471329 15459660 19497792
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18971944 28416484 20507565 19118383 21576760 18583988 15066279 20471329 18452278 25477519 21592330 15367657 21118972 20533398
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
E2F4 TOPBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17531812 15195143
CSNK2A1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18971944 20507565 19118383 21576760 18583988 15066279 20471329 18452278 21592330 15367657 21118972 20533398
E2F4 AURKB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 15033491
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
TERF2 TERF2IP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17145710 19651898 15316005 27214791 10888888 21217703 19287395 15383534 26496610 23086976 19164295 15100233 16880378 26450775 21829167 10850490 28082411 23307557 21044950 14565979
AURKB KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28992084 31881080 23940115 25512391
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153