PIN1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16713569
9499405
|
CCNB2
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
CDC25A
|
CHEK2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11298456
5213933
|
CDC25C
|
PLK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11897663
8703070
|
PIN1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11774038
16713569
|
CKS1B
|
CDK2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
PKMYT1
|
TGOLN2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23241949
8412360
|
CDC25B
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
CDK1
|
CDC25B
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
12107172
|
CDC25B
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
7880537
|
CDK2
|
CDC25A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.81
|
0.81
|
Signor
|
17110335
|
CDC25A
|
CDK2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
22263797
|
VAPA
|
CCNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CKS2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CDK2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
CDK1
|
CDC25A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12411508
|
CDC25A
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
10454565
|
CHEK2
|
CDC25C
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
12835754
|
CDK1
|
CDC25C
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
8119945
|
CDC25C
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
19574738
|
CCNB1
|
PKMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
RPS6KA2
|
RPS6KA3
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
CCNB2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.85
|
STRING
|
36370105
|
CCNB2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
PLK1
|
CDC25C
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
14532005
5216753
|
CDK1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
RPS6KA3
|
RPS6KA6
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
CDK1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14681455
33961781
33422522
17679094
25852190
26496610
24302728
19483727
12853968
26186194
21308745
8463339
28514442
9053846
23602568
32707033
|
SKP2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11237742
22959436
10790373
|
CKS2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
26344197
25852190
18471975
26496610
26186194
32707033
28514442
23602568
19786724
|
PLK1
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10037602
9499405
16118204
16713569
16189514
|
RPS6KA2
|
RPS6KA6
|
â—¼ CORRELATES
|
|
+
|
0.89
|
0.89
|
CCLE
|
31978347
|
PKMYT1
|
PLK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CCNB1
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CDC25A
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CCNA2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CDC25C
|
PLK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
SKP2
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
20160477
33989513
9858587
33422522
24632684
15355997
7553852
26496610
16209941
27720894
31181401
26186194
10559858
28514442
18604603
|
SKP2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9858587
15355997
33989513
|
CCNA2
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9858587
15355997
33989513
|
RPS6KA1
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23708659
|
MAPK10
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20220133
|
PKMYT1
|
CDK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10373560
10504341
12738781
|
SKP2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
20160477
23455922
26496610
22770219
23602568
7553852
9636170
9858587
15355997
25852190
10386600
16979657
28514442
16189514
18604603
33422522
19686743
19270695
26186194
10559858
|
MAPK8
|
PKMYT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19204086
|
CCNA2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CCNA2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
PLK1
|
CCNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
11242082
|
CDK2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CCNB2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDK2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
CKS2
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
30674583
18471975
26496610
28514442
19786724
|
CKS2
|
CCNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
28514442
19786724
|
CCNE1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
CCNA2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
PIN1
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
CDK1
|
PKMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
HADHA
|
HADHB
|
â—¼ CORRELATES
|
|
+
|
0.93
|
0.93
|
CCLE
|
31978347
|
CKS1B
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
8601310
5220942
|
CHEK1
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
CDC25C
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
CDK2
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
19561641
|
CDC25A
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
CCNE2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
CKS2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
23455922
25852190
26496610
26186194
28514442
19786724
|
CCNB2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CDC25C
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CDK2
|
CCNA2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.97
|
0.97
|
Signor
|
10652300
|
CCNB1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CKS1B
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
CCNB1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
8978686
23455922
15980415
24771265
15670215
15514162
26496610
20837141
25728284
9891079
33854239
10330164
8867812
23602568
14681455
11433299
16431923
9716181
20587660
28137908
14701826
14536078
17361108
33854235
10827081
8662825
9472014
25852190
16223725
9192873
11940657
12839982
11132966
10359664
7799941
21092281
8647086
8756624
19631451
28514442
21372285
9660939
17431037
17254967
29439025
19470470
21241890
9840943
17970072
1388288
18559665
12800980
15004009
26186194
24358021
23853094
12529437
15557281
|
HADHA
|
HADHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCNA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNB1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNE1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
BRSK1
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15150265
|
BRSK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
10681541
11551930
9836640
11333986
10744722
20068231
15791647
9278511
15629715
27246979
12941695
9278512
10557092
10786669
15150265
9543386
19648910
7982962
20639859
|
CDK2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
81.0
|
1.0
|
Omnipath
|
8756328
7553852
11377199
17145710
23602568
11983168
12044161
19483727
12853968
16209941
8397207
15455144
19631451
8475101
24358021
15557281
8684460
12941338
15647383
15890360
21447625
9380407
26496610
11141566
25852190
15189033
14656438
20733051
21241890
10652300
25669885
12244298
26186194
10930425
9660939
10477583
24302728
15239650
19773423
8463339
16290148
10924145
11907280
17361108
17254966
8662825
15828833
18471975
9724724
7630397
10559988
9716181
11940657
23455922
|
CCNA2
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
1833185
10924145
8423786
|
CCNB1
|
CDC25B
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
8119945
1836978
12754270
20360007
8440392
10827953
12411508
|
PKMYT1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
9001210
12814430
10373560
18319725
12738781
26496610
23397142
10504341
|
CDK1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23799914
34224728
20117088
16784539
24358021
24508230
19470789
10973963
17283331
20228808
18347064
11242082
12397081
10362260
24582498
15582998
20367638
1833185
12447691
9001210
2570636
24101512
23543736
11331587
12524548
22726437
27626412
|
PLK1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
20404109
16854412
26899266
19364923
25362646
20126263
12524548
26729093
11242082
12447691
|
CCNB2
|
CDC25B
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
8119945
1836978
12754270
20360007
8440392
10827953
12411508
|
CCNB2
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8348613
12814430
10373560
11313986
16123593
12478465
|
CDC25A
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
8617791
17303408
18073536
1075565
17568790
18786381
17660363
15279786
|
SKP2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
11237742
12648680
11900249
16697054
18931676
19809470
15459660
|
CDK2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
17145710
16223725
21092281
15004009
10962581
9840943
8643455
24358021
8861947
21372285
17570479
11237742
10330164
22558078
10652300
19561641
10477583
18691976
23853094
12144826
10500095
1388288
10827081
17970072
28137908
19470470
8756624
10809788
14536078
15364936
|
CCNE2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
CCNE2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
SKP2
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
CDK1
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
CHEK2
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11438669
15459660
15810020
15867354
17296736
17464182
17568790
18048416
18566216
18756267
18931676
18971944
19686080
19788416
20019063
20126263
|
SKP2
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
CHEK1
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
15459660
15798197
17102137
17116885
17296725
17384638
17568790
17582221
18677104
19793801
20126263
|
CDC25A
|
CDK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
1075565
15279786
17303408
17568790
17660363
18073536
18590585
18786381
7575488
|
CDK1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17303408
18073536
1075565
19413330
15279786
7575488
17172867
17570479
12411508
18167338
27580187
18927152
19652693
18590585
12124778
18786381
17660363
21379580
15917306
22263797
27038604
17568790
|
RPS6KA1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
23708659
|
CHEK2
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
52.0
|
1.0
|
Omnipath
|
18566216
12676583
15810020
18285803
12759351
14681206
20860841
16682204
9836640
10724175
29725502
23855452
20126263
18480045
11298456
20587702
15459660
20514219
22263797
27038604
17464182
14559997
12399544
17568790
24882577
19101576
|
CHEK1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
75.0
|
1.0
|
Omnipath
|
12676583
22040655
29435105
12759351
14681206
18677104
20860841
15798197
19793801
22655267
12963847
16682204
14752276
16647857
15736430
29725502
17116885
17582221
20126263
16697662
18167338
19075565
9278511
18480045
17384638
21148633
21252624
27493659
12110582
17030123
23335075
20068082
11298456
27908669
27213455
25936524
15459660
28150240
20798862
22263797
27038604
17296725
14559997
12399544
17102137
17568790
16488126
|
CDC25A
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
8617791
11602341
17303408
18073536
1075565
15279786
7575488
10454565
11154267
12411508
16189514
1396589
18590585
18786381
17660363
12388094
22263797
27485204
17568790
15659558
|
CHEK1
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
15459660
15798197
17102137
17116885
17296725
17384638
17568790
17582221
18677104
19793801
20126263
|
SKP2
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
PLK1
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11073952
17596790
18931676
19270156
19622404
19686080
8127874
|
CHEK2
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11438669
15459660
15810020
15867354
17296736
17464182
17568790
18048416
18566216
18756267
18931676
18971944
19686080
19788416
20019063
20126263
|
CDK1
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
CDK1
|
CDC25B
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
8119945
1836978
12754270
20360007
8440392
10827953
12411508
|
MAPK8
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19638579
21807946
|
PLK1
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18931676
19270156
21640712
19622404
19686080
|
CDK1
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17303408
18073536
1075565
15279786
7575488
21640712
9733650
8440392
17570479
9141461
19652693
18590585
9585407
12124778
18786381
17660363
15917306
9268380
12107172
17568790
20801879
12766774
|
CHEK1
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
27038604
17296725
17003105
18677104
15798197
17102137
17116885
17568790
17582221
19793801
20126263
17950252
9278511
21091437
17384638
16314342
15459660
|
CHEK2
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18566216
17464182
15810020
17568790
20126263
15459660
|
CDK1
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
CHEK2
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11438669
15459660
15810020
15867354
17296736
17464182
17568790
18048416
18566216
18756267
18931676
18971944
19686080
19788416
20019063
20126263
|
PLK1
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11073952
17596790
18931676
19270156
19622404
19686080
8127874
|
CHEK1
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
15459660
15798197
17102137
17116885
17296725
17384638
17568790
17582221
18677104
19793801
20126263
|
MAPK8
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12742231
20220133
8119945
7513216
|
PLK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
14968113
19622404
11202906
10980711
20668692
19597481
19686080
19270156
12595692
16189514
19503101
17634129
19607708
14532005
24525428
27038604
22852086
16753148
17596790
28396830
17307877
11897663
18931676
|
CHEK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
29774099
17145710
10391675
18321553
29425806
10214922
20716119
18677104
20860841
15798197
19793801
11836499
10681541
21152443
12505356
27603133
24505404
11333986
9836640
11551930
17097061
23880065
15736430
26485758
11240139
9889122
20068231
17116885
12742231
28442587
17582221
20126263
14681223
9278511
17384638
15629715
12814430
11313986
11741534
20068082
24079846
26542114
9278512
9659898
15705874
11027648
24525428
9914179
10557092
15459660
10676638
9810229
15150265
10209160
17296725
15296723
25512053
12399544
21035467
9543386
9744884
19490919
28396830
17102137
17568790
16488126
16330544
12478465
|
CHEK2
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
18566216
19165865
29774099
27427153
29302370
15810020
18321553
29425806
15707569
20860841
21152443
10681541
12711320
12505356
11551930
9836640
11333986
11583839
17097061
23880065
26485758
20637859
10744722
11240139
26633535
9889122
20599567
20068231
23788960
16481012
25914884
20126263
23705030
15791647
9278511
21924579
15629715
27801830
10097108
12814430
28094252
11313986
12941695
11728459
11053450
9278512
10557092
15459660
10435585
27038604
15150265
17464182
9543386
17568790
15282313
16488126
12478465
12835754
|
CDK2
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20530684
28396830
|
CDK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
17349584
17110335
17303408
18073536
1075565
11836499
15279786
8348613
7575488
20668692
24710276
9733650
12036951
20068231
8440392
12742231
32075732
16189514
9141461
16123593
18669648
19652693
18590585
9585407
12814430
10864927
10373560
18691976
11313986
12124778
18786381
17660363
18272572
8119945
15917306
27038604
9268380
17596790
28396830
17568790
19350548
16964243
10037602
18212344
12478465
12766774
|
PPP1CA
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9543386
14592972
11897663
16467385
|
CDK1
|
PLK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17596790
17660363
18414028
18543256
18590585
18995830
19652693
19686080
7575488
9892021
|
CKS1B
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
26186194
19786724
9276444
9774639
23602568
20015071
25416956
7809159
18471975
26496610
25852190
16189514
|
PKMYT1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
91.0
|
1.0
|
Omnipath
|
17145710
19901323
26899266
19690332
16497976
15592455
19413330
11202906
17480229
25609063
18083107
20360007
19415658
14972559
19534553
9552418
10564259
16083285
24651440
7743995
20068231
18452278
12912980
25344910
11730318
96108162
12049736
18669648
12814430
22494620
10373560
18691976
28539822
15964826
26131711
12738781
19917613
17487921
17192257
20068230
10504341
20419782
19651622
9001210
20058876
9268380
10209160
23166842
8428596
19369195
25435947
24630986
15951569
17016520
8084605
12186947
7569953
|
CDK1
|
PPP1CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12202491
17145710
17274640
22367880
18088087
17202132
9122166
97225924
10880350
|
CDK1
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17764786
17660363
15279786
15917306
|
CDK1
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
20798862
19837665
18691976
21765472
21907702
29092815
18983824
16629900
22686412
24242917
|
CDK2
|
PPP1CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12202491
17145710
14715909
17274640
16550609
18088087
17570479
9122166
97225924
15212693
10880350
|
CDK2
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7553852
20160477
23602568
25271736
18239684
28446188
23226679
10386600
19270695
26496610
16189514
25852190
26186194
25788262
9858587
22770219
15355997
10559858
23807222
22311674
16979657
9636170
19686743
19270694
18604603
23455922
|
CDK2
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21765472
21965652
21907702
18983824
24242917
|
CHEK2
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26516160
24804719
26437226
29555944
|
PLK1
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
12024051
24844881
18802408
19216791
10973490
18804494
12242661
20126263
16189514
11901158
12493754
|
PRKDC
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
77.0
|
1.0
|
Omnipath
|
31959038
12607004
22669845
18948271
16794575
24492479
15829965
23684611
12805407
20406977
26929199
21482692
27818175
20660628
33870196
11668173
21731742
33879618
15618221
11901158
24421316
21099343
12386164
15096610
24415760
12447382
12855706
15213307
16150728
20599567
16024600
17570479
12447371
28750002
34244606
33901880
15367709
26505995
16940182
33747205
11025670
12024051
24844881
15668230
10973490
20713355
33961649
19151762
16936775
16798742
12607003
30001349
18644861
25361978
20305300
11390408
20501833
15361851
16982735
23380594
15674326
17237275
20160490
20498628
33851958
15282313
25550082
31609975
15975956
11085506
12493754
|
SKP2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11516665
12820959
15071497
15147722
15340381
15459660
15668399
15688063
18931676
19622404
19686080
|
SKP2
|
CKS1B
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11516665
12820959
15071497
15147722
15340381
15459660
15668399
15688063
18931676
19622404
19686080
|
CKS1B
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
23589337
19786724
12813041
18519678
16979657
15772084
12529174
16209941
16189514
11231585
16338391
12140288
11463388
18239684
15980415
17409098
|
PRKDC
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11749722
16319174
|
PLK1
|
PIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
27618008
23633483
16118204
9499405
16713569
25070718
25766872
10037602
22926167
|
PLK1
|
PKMYT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11073952
17596790
18931676
19270156
19622404
19686080
8127874
|
PLK1
|
PKMYT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
18931676
18691976
19270156
26899266
12738781
19622404
27603133
26597303
19686080
|
PRKDC
|
CCNB2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.01
|
1.01
|
PKG
|
28854368
|
PRKDC
|
PRKDC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.22
|
4.21
|
PKG
|
28854368
|