ABL1
|
ARHGEF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CTNNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
ABL1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11753601
9916993
|
E2F1
|
ACTN4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15897325
18319725
|
APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
BAX
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11709054
|
CSNK2B
|
ARAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10094392
5211308
|
PKM
|
ARAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216198
12620389
|
ATF2
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17189429
17700520
|
ATF2
|
GADD45A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17700520
|
E2F3
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18469863
12527885
|
HMGA2
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21339738
|
E2F3
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12527885
18319725
|
ATM
|
HMGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21339738
|
BRCA1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
BRCA1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
23422745
|
CAPN1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BCL2L11
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BCL2L1
|
BAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
BCL2L1
|
BAK1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
BBC3
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22492984
17289999
|
BCL2L11
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
CAPN2
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
21887410
23242420
|
AHR
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11455387
11479581
|
BCL2L11
|
BAX
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BAX
|
CASP12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209154
|
E2F2
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11559537
18319725
|
CAPN2
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12000759
|
CAPN1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12000759
|
BCL2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15210690
|
CAPN2
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12000759
|
MYC
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16169462
21899728
|
RUNX3
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16373335
16738314
|
MYC
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209154
|
CASP3
|
BID
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
BRCA2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19369211
0811159106
|
EZH2
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23624935
21406404
|
EP300
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23353771
23285190
|
FOXM1
|
BRCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20068070
17101782
|
FOXM1
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17101782
|
CAPN1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8695851
|
CASP8
|
CASP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18669646
0712034105
|
CASP9
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
AKT3
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
AKT1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12011067
15573119
|
CASP3
|
AKT2
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17899380
|
CASP3
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18362891
|
CASP9
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12011067
11248093
|
CASP9
|
BIRC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11024045
5213055
|
CASP9
|
BIRC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11024045
5213055
|
NKX3-1
|
CASP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15705778
24252419
|
CASP9
|
CASP7
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
E2F1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12389032
18319725
|
CBL
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CDC27
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0913813107
20439707
|
CCND1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16461912
0506281103
|
CCND1
|
RBL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
CCND1
|
E2F5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
ATF4
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18729081
20101207
|
HDAC1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20049841
20821348
|
EZH2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20132185
21697275
|
TP73
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16526280
22842668
|
FOXM1
|
CDC25A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23240008
|
BTRC
|
CDC25A
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
14603323
5216801
|
E2F3
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15210709
18319725
|
E2F1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15210709
18319725
|
E2F3
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8033208
7958856
|
AURKA
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
CDK2
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10523313
10373557
|
CUX1
|
CDK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12619038
12732645
|
CKS1B
|
CDK2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
CCNB2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
CDC6
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
PCNA
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CDKN1A
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AKT1
|
CDKN1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
CDKN1A
|
RBL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
CDKN1A
|
E2F5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
AHR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12203118
24431146
|
CCNA1
|
CDKN1A
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
E2F3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10030670
18319725
|
AR
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10076995
|
E2F2
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7958836
|
E2F1
|
CUX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18347061
|
E2F1
|
CDKN1C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17173074
20106982
|
E2F1
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15766563
|
E2F1
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20300951
|
HDAC1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17980157
18319725
|
PTEN
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17218262
|
E2F7
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14633988
18319725
|
E2F1
|
RBBP4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
E2F1
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766737
18319725
|
E2F1
|
E2F2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15014447
18319725
|
E2F1
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15271987
18319725
|
E2F1
|
AURKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
15033491
|
EP300
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
EP300
|
BIRC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20660371
19102934
|
EP300
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828133
24058639
|
TP73
|
EP300
|
â—¼ ACETYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11804596
5215037
|
FBXW7
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11533444
5214465
|
MYC
|
FBXW7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20638938
19366810
|
FBXW7
|
CCNE1
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11533444
5214465
|
FOXM1
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16504183
5218380
|
FOXM1
|
G6PC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15933209
|
FOXM1
|
CDC6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24583551
|
FOXM1
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16504183
5218380
|
CCNE1
|
FOXM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15024056
16504183
|
FOXM1
|
CKS1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16314512
|
FOXM1
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18408007
|
TP73
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21245298
10435630
|
MYC
|
MSH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12808131
11983916
|
AHR
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114727
16091746
|
E2F5
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17132729
|
MYC
|
EZH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21941025
19197161
|
E2F2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11564866
18319725
|
E2F3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11564866
18319725
|
AKT1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942906
9804616
|
E2F5
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12150994
18319725
|
MYC
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9988278
|
AR
|
NKX3-1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8943214
|
CCNB1
|
PDS5B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21878504
21987589
|
CCNB2
|
PDS5B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21878504
21987589
|
TERT
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18775701
6742757
|
CASP8
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18362891
|
TP73
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15737644
|
HDAC1
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16464847
24058639
|
HDAC1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18691180
9650586
|
PCNA
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16189514
7908906
|
E2F7
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14633988
18319725
|
CALM3
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
AR
|
APPL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12621049
20610535
|
CALM1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12799359
11988487
|
AR
|
CALM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16619263
20610535
|
CALM1
|
ADCY8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16258073
10075700
|
CALM1
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
PTEN
|
CSNK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12297295
11035045
|
CALM2
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
AR
|
AREG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23415714
20610535
|
CCND3
|
AREG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11469683
16713569
|
ATP6V1G1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
EZH2
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24719098
22956625
|
BMI1
|
PTEN
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19903340
8291464
|
PTEN
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19903340
|
PTEN
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10644997
|
HDAC1
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20037778
19435809
|
E2F3
|
BUB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574595
18319725
|
AURKB
|
BIRC5
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19357306
0900833106
|
E2F2
|
BIRC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17916908
15271987
|
BIRC5
|
AURKA
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19357306
0900833106
|
E2F5
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15271987
18319725
|
E2F3
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15271987
18319725
|
E2F2
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15271987
18319725
|
E2F2
|
CDC6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12411495
|
E2F3
|
CDC6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18541154
12411495
|
E2F2
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766737
18319725
|
RUNX3
|
CASP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15930301
|
BIRC2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17145710
12887920
|
AR
|
CALR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11817565
20610535
|
CREBBP
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12573436
|
CD28
|
CBLB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12193687
23109003
|
CBLB
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CAMK2A
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RUNX3
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24042352
22231444
|
CUX1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14612449
22422878
|
EZH2
|
BMI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21465172
19351856
|
AKT3
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22505453
|
BTRC
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
AURKA
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
AURKA
|
CCNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
ADRM1
|
BUB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
BIRC3
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23070005
18485876
|
CACNA1C
|
ACTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
CCND2
|
E2F5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
CCND2
|
RBL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
CCND3
|
RBL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
CCND3
|
E2F5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
E2F3
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12611887
18319725
|
E2F2
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12611887
18319725
|
CCND3
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16609025
|
RBL2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8253383
18319725
|
E2F2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15510213
18319725
|
CCNB2
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
E2F3
|
CCNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574595
18319725
|
ACTN1
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12223541
5215727
|
CAMK2A
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9768837
8798667
|
AR
|
AHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
23689136
|
EZH2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24457600
23239736
|
AHR
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19815066
17392787
|
AR
|
FGF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12140757
|
ANAPC7
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10922056
10500174
|
ANAPC1
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC27
|
ANAPC7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10922056
10500174
|
CDC27
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC16
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC1
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC10
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC4
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC23
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC5
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC5
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC5
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC5
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC5
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC5
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC16
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC10
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC4
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC1
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC23
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC7
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10922056
10500174
|
ANAPC2
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
ANAPC7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10922056
10500174
|
ANAPC2
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC4
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC23
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC10
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC16
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC1
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC1
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC1
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC1
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC4
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC7
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10318877
10500174
|
CDC16
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC16
|
ANAPC7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10318877
10500174
|
ANAPC4
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC23
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC10
|
ANAPC7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10318877
10500174
|
ANAPC7
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10318877
10500174
|
ANAPC10
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC4
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
PRMT5
|
AGT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATP6V1G2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14667819
5216829
|
EZH2
|
CDKN1C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22821416
19340297
|
EZH2
|
CDKN1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20574448
|
AHR
|
AIP
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6594475
16257957
|
RBL2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8253383
18319725
|
E2F3
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8618861
10733529
|
CAMK2D
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20668654
1000426
|
TFDP2
|
E2F5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11157749
9144196
|
CASP12
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209154
|
BDKRB2
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CCNA2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
APC
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
CCNB1
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ATF4
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
CDK2
|
CDC25A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.81
|
0.81
|
Signor
|
17110335
|
CDC25A
|
CDK2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
22263797
|
CDKN1A
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
16765349
5218735
|
BIRC2
|
E2F1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
28542143
30359437
21653699
|
EP300
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
14968110
30110629
22778253
16787918
33742100
18722353
22731250
|
CCNB1
|
CDC27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
12097298
20080579
16479161
22193957
16921029
19826003
25750436
32076268
20733055
|
NRAS
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
34591642
|
NRAS
|
BRAF
|
â—¼ PROXIMITY
|
✅
|
|
0.81
|
0.81
|
mint
|
30194290
|
ATP6V0A2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
CCND3
|
RBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
BCL2L1
|
BMF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
CCNE1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
BCL2L2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
BIRC2
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
ANAPC13
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
CCDC6
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BRCA1
|
ASH2L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
26831064
|
EP300
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10327051
24069158
|
EDNRB
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BAD
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19427863
17274640
|
MYC
|
RBBP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
PSMD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
32140074
|
MYC
|
CHD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
AXIN1
|
AXIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22682247
20128690
|
CDC16
|
BUB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BMP4
|
CALR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ATP6V0A1
|
ATP6V0E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
CDC27
|
APC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10922056
12956947
|
BAD
|
BCL2
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15694340
|
CCND1
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
BCL2L1
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9539746
|
AHR
|
ARNT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
ATR
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10608806
20798688
|
CBL
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8621719
14725908
20675402
8641358
19380743
|
CCND3
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
16782892
33854235
26496610
9716181
33961781
26186194
23455922
|
CDK3
|
AKT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCNA2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PCNA
|
CCNE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PCNA
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AREG
|
ADCY9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CDC27
|
BUB3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
27114510
22193957
33961781
32152539
32076268
21926987
|
CCND2
|
RBL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCNA2
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RBL2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9891079
8253383
|
AKT1
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
31575057
|
EP300
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
AKT1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CCND1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CDC6
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
BTK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
BRCA1
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25531315
23624935
|
E2F1
|
E2F3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
35140242
24981860
20106982
|
AKT1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
MYC
|
TERT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32140074
28628118
28205554
|
PCNA
|
CCNB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
7903056
33961781
8101826
|
AKT1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
CCNB1
|
CCNB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
19879842
26344197
|
AR
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
APAF1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CCNB1
|
PKMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CCND2
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
AXIN2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
10911903
|
CDK3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
CDKN1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
ANAPC2
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
AXIN1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
7025676
19131971
|
CASP9
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11242052
8900201
25241761
1067155
15941357
11230124
15507451
18723680
17437405
|
CDK2
|
RBL2
|
â—¼ PHOSPHORYLATION
|
|
|
0.85
|
0.85
|
Signor
|
11157749
|
CCDC6
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22863883
20498639
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
AKT1
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15833858
28628118
28205554
|
AKT1
|
PTEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
BAK1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
CCND2
|
RBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
E2F1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
CASP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16183855
11406564
|
AURKA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22110403
14990569
26831064
|
BRCA1
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
9244350
10373534
|
CDK2
|
CDC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9566895
9889196
10339564
|
ATF4
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
14630807
17872950
10350644
12471036
16219772
|
EP300
|
RUNX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24229708
15138260
|
CCDC6
|
FBXW7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25885523
23108047
|
AKT1
|
PTEN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12297295
19903340
12077256
28628118
20605778
28205554
10866658
20596030
|
AKT1
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10869359
25241761
28628118
28205554
|
ATP6V0A2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
RBL2
|
RBBP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33961781
17531812
|
RBL2
|
TFDP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33961781
17531812
|
CCNB2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
BIRC2
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
BRCA1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
BCL2L11
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CDKN1A
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
BUB1
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11283619
25241761
|
ASH2L
|
CHD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20085832
24705355
|
ATP6V0D1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9727492
15659383
9727491
12097160
11832478
12196516
11085743
|
CASP3
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10364179
11399776
18723680
|
CCNA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25091198
16713569
9244350
10373534
|
CASP8
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15254227
11832478
18669646
11437602
8962078
|
BIRC3
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17069460
9384571
|
CCND2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9840943
28514442
33854235
33961781
26186194
23455922
9178893
|
CCNE2
|
CDK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9840943
28514442
26186194
33961781
|
MYC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15616592
16287840
32140074
16126174
17157259
12776737
|
AKT1
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21901101
15224190
21775285
20333651
18182168
11116148
|
MYC
|
PDS5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
17353931
29467282
|
CASP8
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12887920
27810922
15069192
22274400
|
CDC23
|
BUB3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
20360068
|
BIRC7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
25416956
33961781
26186194
22711539
21113135
|
CDC23
|
CDC26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26496610
20360068
|
BCL2
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CASP3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ATF4
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CACNA1S
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CACNA1S
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V0D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CACNA1S
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ANAPC4
|
BUB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ARAF
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BBC3
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EP300
|
TP73
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CCNA2
|
HIST1H1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ABL1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ATR
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
AXIN1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
BAX
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CCNE2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CAMK2D
|
CAMK2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ACTN1
|
ACTN4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22863883
22939629
|
ATF2
|
BACH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
23661758
20102225
|
BRCA1
|
RBL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21102443
11521194
|
BRCA2
|
PDS5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22293751
27924011
|
BIRC5
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11024045
11069302
16189514
25241761
|
EP300
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15951563
10567390
11788592
|
CCNA2
|
CDK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
8626584
33961781
26186194
23602568
|
CCNE1
|
CDK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
11733001
33961781
26186194
23602568
|
CCNB1
|
CDK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
27030811
|
CCNA1
|
E2F1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16774918
10022926
|
E2F1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10734134
9468140
17980157
26468294
9468139
|
AHR
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10999956
17392787
21988832
|
CCNE1
|
FOXM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16504183
15024056
|
PSMD3
|
ADRM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24811749
28514442
22863883
33961781
26186194
26344197
|
PCNA
|
CCND3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
33961781
7908906
|
CBLB
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10022120
25814554
|
HDAC1
|
BUB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15388328
19407811
|
BUB3
|
BUB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16760428
16189514
25416956
21988832
26496610
26148513
9660858
11283619
33961781
26186194
20220147
|
CDC23
|
BUB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20360068
28404789
26496610
33961781
32707033
|
RBL2
|
CCND3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
26186194
16600870
10572252
|
AHR
|
AIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
CASP7
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16339151
30948266
9384571
|
CASP10
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BMP4
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
AR
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
BUB3
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
BLNK
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
BRCA1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17352427
12024016
|
RBBP4
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10220405
16713569
26831064
|
HDAC1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21102443
10220405
16713569
|
CCNB1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
11278247
23246971
9244350
|
CCND1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17334399
16713569
9244350
|
BUB1B
|
BRCA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28985013
10749118
32286328
|
BIRC2
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
17069460
9384571
11084335
19258326
11106668
|
BIRC5
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
11170436
9850056
|
BIRC7
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11024045
23563149
11084335
|
E2F1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8458319
7969176
9199321
1530885
11245432
|
AKT1
|
TERT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28628118
15843522
28205554
10224060
18775701
|
CCNA2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
12853968
26186194
10930425
|
CRKL
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15143164
8978305
10194128
9747873
|
ATP6V1E2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
BUB1
|
BUB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9914370
28514442
20360068
26148513
33961781
26186194
25852190
20220147
|
BIRC5
|
CASP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11024045
16189514
11170436
9850056
|
CDC6
|
CCNA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9566895
9889196
10339564
|
CASP7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16339151
9384571
11084335
33961781
15580265
19258326
|
CDC16
|
BUB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10477750
20360068
24151075
11030144
33961781
32707033
|
RBL2
|
CCNA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
12006580
17531812
33961781
26186194
8253383
|
CDC26
|
CDC27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20360068
12956947
16364912
25723520
33961781
32152539
32076268
14657031
10922056
21043528
|
ANAPC15
|
ANAPC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
AIP
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12065584
9111057
11259606
|
BMPR2
|
BMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28126904
12045205
7673243
7644468
8702914
|
TFDP2
|
E2F5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
ATP6V0A1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
CCNA2
|
E2F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
CCND3
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
CCNA2
|
RBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
ANAPC13
|
ANAPC15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
BAK1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
BBC3
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CCNE1
|
HIST1H1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CCNB1
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9727492
|
BIRC3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CDK2
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CDK2
|
RBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CCNB1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CCNA2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ATM
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9168116
17409407
10212258
20798688
11375976
9168117
|
CRKL
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16443220
22286129
7493940
14604282
8978305
9820532
18835194
9710592
33961781
8524328
19823681
7926767
16955467
24412932
|
ABL1
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12543778
1712671
8112292
21653319
11780146
|
ABL1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15556646
11494134
16713569
9174058
20675402
9195915
14604282
10829062
14725908
8626543
12475393
19380743
19823681
16955467
|
MYC
|
ABL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21400515
23029531
19602047
|
ABL1
|
ATR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20798688
|
AXIN1
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16199882
22682247
10228155
29045831
18786926
20128690
19131971
26496610
10811618
9734785
29713058
23277359
17510365
|
APC
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10200466
17297457
9973322
|
AXIN2
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10966653
10911903
9554852
|
BRAF
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
25241761
31980649
28628118
17979178
20130576
34017080
33961781
28205554
|
ATF2
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9511728
10777595
7843287
|
ATF2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23800081
10506225
|
ATM
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
29656893
10783165
11016625
10866324
10550055
15713674
18344987
10608806
17478428
|
E2F1
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22832221
23993922
12527885
|
ATM
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15546863
15899889
|
ATR
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
23901102
29656893
16713569
11016625
10608806
17478428
|
EZH2
|
ATRX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9499421
25417162
27634302
|
BRCA1
|
BACH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17664283
15208681
16713569
19369211
17525340
15125843
15242590
16391231
25252691
11301010
11877378
|
BCL2L11
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22492984
12242151
|
BAX
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
CAPN1
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
19931333
21887410
23242420
|
AKT3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14766748
15642728
17525161
|
BBC3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15574335
|
BBC3
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11463391
11463392
23430059
|
BBC3
|
BCL2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11463391
11463392
23430059
|
E2F1
|
BBC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14684737
17263886
|
E2F1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11559537
18319725
11704823
|
AR
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21310825
20610535
18196538
|
CAPN1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12000759
|
BCL2L11
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
23430059
23850759
9430630
|
BCL2L11
|
BCL2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
23430059
23850759
9430630
|
E2F1
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23152504
19893569
16243973
|
E2F1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15240700
12402042
15024076
|
CASP10
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16186808
15772077
|
EP300
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21102443
19887647
10655477
11782371
16713569
21212407
22787115
|
MYC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12646176
11916966
16713569
20215511
9788437
30415952
14612409
|
AKT1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21242970
10542266
20085797
19074868
|
BRCA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11477095
17664283
16713569
21135251
19369211
9774970
25184681
14636569
24085845
34408138
25652403
14499622
29656893
|
CDK2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
16713569
10373534
9244350
8764100
|
BRCA1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11498787
16713569
10783165
15886699
16260778
|
E2F5
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17106239
|
E2F2
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17106239
|
E2F3
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17106239
|
EZH2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19079346
20574448
|
CASP3
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12149654
|
MYC
|
BRCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
AR
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22038727
20610535
23554843
|
BIRC7
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
25416956
11024045
11084335
11801603
|
BIRC2
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16701639
32296183
16189514
25416956
25241761
27197231
16339151
11084335
9545235
15069192
19153467
|
CASP9
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16701639
25241761
21988832
16339151
9545235
15069192
|
MYC
|
CASP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
CASP12
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15725726
12097332
|
BTK
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10826882
10427990
9408950
7629518
|
CCND1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
PCNA
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15681588
7908906
8101826
33961781
7903056
21654808
|
CCND1
|
TFDP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
FOXM1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23812424
19097132
11572993
|
RBL2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
9891079
17531812
25852190
9472014
33961781
26186194
23602568
10825149
23455922
9188854
|
CDK2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26186194
10330164
23455922
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
CDK3
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11733001
15838516
8846921
|
MSH2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PKM
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ATP6V1A
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
ANGPT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
TFDP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
E2F1
|
CCNA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8458319
7969176
12501191
35140242
9724724
|
E2F1
|
BMI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23796898
17360938
16582100
|
E2F1
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12629508
|
E2F1
|
FOXM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21518729
22802261
|
E2F1
|
CCND3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12611887
16300731
|
E2F3
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14576826
10766737
18319725
|
EP300
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10753885
15123636
15126619
|
E2F1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11564866
18319725
90001421
|
E2F1
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15240700
12389032
18319725
|
EP300
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11268218
16713569
18263614
12937166
24939902
14988403
33742100
|
EP300
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12573436
10999956
|
FBXW7
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27795300
31569395
35140242
15150404
33494392
15498494
28007894
23750012
31638140
17646408
28209614
16023596
17157259
25716680
20970423
23791182
32021252
30606768
32345600
17873522
33821962
31152129
20848231
32047362
22524983
17314511
25720964
31285543
32350066
33086033
15103331
|
FBXW7
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19956254
18559665
22388891
14536078
16818231
15364936
17646408
28209614
14739463
24298052
28850619
31152129
33288957
32051583
11533444
11565033
17298674
16338364
31868589
21070969
11565034
17434132
15980150
|
FBXW7
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15592418
33824269
|
MYC
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28628118
17314511
12584560
29467282
28205554
30415952
|
MYC
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314511
18271930
34147029
26496610
30415952
18003922
22286234
24951594
|
MYC
|
FGFR4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
RBBP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
ATP6V1G2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
MYCT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22672838
11909865
|
MYC
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16846534
16489011
18562319
|
MYC
|
NRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ADCY9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19149881
24299953
|
MYC
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
AXIN1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19131971
20399964
|
MYC
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10899308
17093053
|
NKX3-1
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16697957
|
E2F3
|
TP73
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15210709
|
TP73
|
CCND3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19861536
|
HDAC1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11929879
16189514
16713569
14988403
|
E2F3
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15510213
18319725
11491305
|
CALM3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
CALM3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CALM1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
CALM1
|
CAMK2G
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10860555
20668654
|
CALM1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CSNK2B
|
ANGPT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CALM2
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CALM2
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
APC2
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9601641
10980707
|
HDAC1
|
RUNX3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18430739
22274925
18850007
|
AURKB
|
BIRC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11516652
31315909
19951914
20430883
21554500
23945651
19357306
29568061
21051298
32738097
18477699
17681274
17099693
19995937
16291752
27332895
12419797
31586073
24571573
|
E2F3
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10766737
10733529
18319725
|
CANX
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14681859
2450918
10064069
|
AKT2
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23092893
22505453
|
E2F3
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18776222
22894933
|
BUB1B
|
CDC27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
20360068
25246557
21300909
25852190
10477750
22193957
11030144
25012665
20212161
21926987
27114510
25673878
26811472
25306918
23754430
32076268
21525009
32707033
22100920
20951947
18722180
30341343
29432156
33961781
32152539
23007861
|
CCND2
|
TFDP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
CCND3
|
TFDP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
AKT2
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10869359
|
CDC16
|
CDC27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24100295
20360068
17187060
21186364
26496610
22193957
9356466
20733055
21043528
27114510
7736578
16648845
25306918
12956947
9628895
32076268
22939629
10922056
16364912
33961781
27173435
32152539
9405394
14657031
26344197
|
CDC27
|
CDC23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20360068
22792066
26496610
22193957
17942546
22280307
21043528
27114510
16648845
32934012
12956947
32076268
20686030
22939629
10922056
16364912
27173435
32152539
14657031
26344197
|
CDC23
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
10500174
|
ANAPC4
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25383541
10500174
|
ANAPC5
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
10500174
|
CDC27
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25383541
10500174
|
CDC27
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
10500174
|
CDC27
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
10500174
|
CDC16
|
CDC26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
25416956
21988832
20360068
26496610
25723520
19668213
33961781
21516116
26344197
|
CDC23
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318877
10500174
|
ANAPC10
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318877
10500174
|
CDC16
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318877
10500174
|
CDC16
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318877
10500174
|
ANAPC10
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318877
10500174
|
CDC23
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318877
10500174
|
CASP10
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8755496
8962078
|
E2F3
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18319725
14532106
|
AHR
|
AIP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9447995
18805402
17329248
|
BMPR2
|
BMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10880444
10712517
25938661
7791754
|
E2F5
|
RBL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7760804
11756542
16600870
17531812
|
ABL1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
CDK3
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
EP300
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BCL2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CCNA2
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CCND2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
GADD45A
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CCND3
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
BUB1
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
BIRC2
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
ABL1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
MSH2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
CCND2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
BAX
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
B2M
|
CALR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
E2F5
|
RBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
CCNB2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CACNA1C
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
8087759
20953164
|
ATP6V1B1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
BCL2L1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
CCNA2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
BTRC
|
CDC25A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
CCNA1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
FBXW7
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V0D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CCNB3
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
14681455
12185076
|
CCND3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ANAPC15
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ANAPC1
|
ANAPC15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ANAPC15
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ANAPC15
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ANAPC15
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CCNA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
AURKB
|
BIRC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
ANAPC15
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
ANAPC15
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ANAPC1
|
ANAPC11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
BUB1
|
BUB3
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
11402067
|
BAX
|
BCL2L11
|
â—¼ PROXIMITY
|
✅
|
|
0.94
|
0.94
|
mint
|
7034061
19427863
|
BMF
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
17289999
16697956
11546872
|
CKS1B
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
8601310
5220942
|
CDK2
|
CDK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
23455922
26186194
33961781
|
PCNA
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
15225546
12171929
16189514
8858149
|
EZH2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
TFDP2
|
E2F3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
7739537
33961781
8755520
26186194
|
ATP6V1B2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CDK2
|
CDC6
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.94
|
0.94
|
Signor
|
10339564
|
CDKN1A
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
CALM3
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CALM2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
CCNA2
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
EZH2
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
BRAF
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
CDKN1A
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
16765349
5218735
|
HDAC1
|
RBL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
9858615
9724731
10969803
|
EZH2
|
RBBP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
21123648
26496610
27705803
20123894
34518534
28068325
33961781
24981860
27634302
24457600
|
TFDP2
|
E2F2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
28514442
16189514
7739537
33961781
8755520
26186194
|
ATP6V1E1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
ANAPC16
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
BUB1B
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
ACTN1
|
ACTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ANAPC11
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CACNA1C
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
CACNA1C
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
CCNE2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
ANAPC10
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
ANAPC5
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
CAMK2A
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CDK2
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.95
|
0.95
|
Signor
|
15964852
|
ANAPC5
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
CASP9
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5221774
9390557
|
ATR
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
14657349
21285353
33005030
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
CCND1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9840943
28514442
8647086
33854235
8479754
26496610
33854239
33961781
23455922
21654808
9178893
|
CCNB1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
20733051
28514442
9891079
7799941
8397207
25852190
26496610
33961781
26186194
23602568
10995390
23455922
30674583
18471975
|
CCNB2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15232106
28514442
24358021
33961781
26186194
23455922
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
CDK2
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
19561641
|
EZH2
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
21685935
15520282
10581039
24771265
31130994
22439931
26344197
|
ATP6V1A
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CAMK2B
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
CCNE1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
ATM
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
ANAPC10
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
CDC6
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
ANAPC10
|
ANAPC13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CRKL
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9162067
9129019
16982329
9590251
8621483
25814554
10907644
10608804
15107835
7545163
9092574
9195915
12244174
18835194
9311917
8524328
16503409
24886428
10657627
14604282
9820532
8662998
9461587
9851874
11399323
9344843
11157475
10204582
9660791
15556646
8978305
11553620
8626543
9988765
33961781
11263968
15358160
11133830
|
CCNE2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
CCNE2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15232106
9840943
28514442
24358021
9858585
26496610
14681455
25852190
9840927
33961781
26186194
23602568
23455922
|
TFDP2
|
E2F1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
7739537
9501179
9704927
35140242
9368098
8755520
26186194
33961781
|
RBBP4
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
9520398
19703393
31435636
9150133
10444591
21258344
12943729
11102443
9885572
27068747
10471499
26496610
34518534
20127688
11171972
10734134
11470869
20585571
10220385
12091390
17643391
21670149
11602581
17827154
22939629
9150135
23752268
16713569
9790534
27705803
19686092
24981860
33961781
11302704
11118440
15451426
12920132
26344197
|
BUB3
|
BUB1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
25416956
25482201
21988832
25246557
11702782
25852190
25505175
25383541
22000412
26496610
22193957
29973720
25012665
28410192
23791783
21937719
25669885
9660858
12419313
19407811
32707033
11535616
22100920
27939943
24151075
28404789
25833949
32152539
26186194
33961781
20220147
|
CAMK2A
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
BLNK
|
BTK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21482705
12093870
10498607
16969585
10556826
21822214
|
AIP
|
AHR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16257957
9837941
9111057
7961671
16582008
10986286
11013261
12065584
9083006
|
ATP6V1B1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ANAPC7
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ANAPC1
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ANAPC1
|
ANAPC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ANAPC7
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ANAPC16
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ANAPC15
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
ANAPC1
|
ANAPC13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
ANAPC10
|
ANAPC15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
ANAPC16
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ANAPC16
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ANAPC16
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ANAPC10
|
ANAPC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CDC23
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
ANAPC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
ANAPC16
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
CDK2
|
CCNA2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.97
|
0.97
|
Signor
|
10652300
|
ANAPC5
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
BUB1B
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ANAPC15
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
CDKN1A
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16765349
5218735
|
CDC16
|
CDC23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
20360068
26496610
33961781
27173435
10318877
22939629
26344197
|
ANAPC10
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
AHR
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
BUB1B
|
BUB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC16
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC5
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC16
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC1
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC13
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC4
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC10
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC13
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC16
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
BAX
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ANAPC7
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ANAPC13
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BAK1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CCNB1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CACNA1C
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
BUB1B
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ANAPC7
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CCND1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ATP6V1F
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
CDC16
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
ANAPC1
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
ANAPC5
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
BUB1B
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
ANAPC10
|
ANAPC11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
7834748
9388232
17446862
9463381
20603619
10611223
14681455
11483855
33961781
19168699
15990872
9305851
15849194
|
BAX
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21778226
18981409
15899854
32064756
10620799
21199865
17289999
9194558
8358790
21671007
16642033
21458670
22262057
9388232
10716992
20865015
14980220
9111042
24141421
17097560
15231068
9463381
33961781
17525735
29749471
23479509
26004684
|
BBC3
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
15694340
16697956
14681455
17289999
33961781
11463392
26431330
|
BID
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
19074266
11583631
9727491
9463381
15520201
14681455
17289999
18835031
12624108
|
CCNA2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8475101
28514442
16431923
33854235
11940657
10559988
15189033
17361108
16290148
14681455
17254966
8662825
25852190
15557281
23455922
19483727
18471975
11141566
10924145
15828833
21241890
19631451
11377199
18177895
8684460
26496610
9716181
12853968
11907280
23602568
9724724
15647383
14656438
19773423
12941338
15239650
24302728
25669885
15890360
7630397
8756328
8397207
21447625
22231403
20733051
9660939
24358021
12044161
33422522
11983168
33961781
26186194
7553852
16209941
12244298
9380407
8463339
15455144
10930425
|
CDK2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
28137908
16431923
29439025
9891079
18559665
33854235
11940657
15004009
17431037
17361108
33854239
14681455
17254967
8867812
23853094
10827081
10330164
8662825
25852190
15557281
9192873
23455922
21092281
14536078
21372285
21241890
19631451
16223725
26496610
1388288
9716181
9472014
15980415
14701826
23602568
8978686
11433299
11132966
24771265
12839982
20587660
19470470
10359664
15514162
17970072
9840943
25728284
9660939
8647086
24358021
7799941
12529437
8756624
33961781
15670215
26186194
20837141
12800980
|
ARNT
|
AHR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8065341
28514442
11768231
9704006
11259609
7488247
19380484
20006590
22138065
11025203
10617682
23477502
9887096
31675361
12024042
12139968
11551916
17392787
18096572
8384309
10619402
7628454
19390533
26350169
8631989
8621524
10671489
33961781
10395741
8619634
|
CCNE1
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ADRM1
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ADRM1
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
HDAC1
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ANAPC4
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
ANAPC10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ANAPC10
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDC16
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ANAPC10
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
HIST1H1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDC23
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC5
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDC26
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC4
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDC16
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC7
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC10
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC4
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
ANAPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC1
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC4
|
CDC16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC4
|
ANAPC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ATM
|
ABL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ABL1
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
ABL1
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
ATM
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
17145710
17303408
22334513
11375976
11804596
23331499
21071413
16163361
17570479
18988627
9168116
23847781
9168117
20798688
15964794
19788416
9561848
22084676
12607003
10212258
15459660
11877377
15686624
17409407
|
BRCA1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12919958
12024016
17352427
|
ABL1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
23318434
10391235
21188172
25666857
20841568
11278685
23331499
27294865
25893286
21199784
17535448
21051857
10391250
18988627
10391249
28690977
25341038
19788416
26512706
10391251
20195489
12070014
15459660
20057499
15686624
21435002
11223036
|
ABL1
|
BCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9407116
10405761
12522270
11780146
8622703
9178913
1712671
12124177
7529874
9467953
8955135
20841568
8112292
16912036
12543778
11376433
|
ABL1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
22553782
24974292
29066624
15657060
20841568
28177918
|
ABL1
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
12445832
15212693
12573241
8629002
17932028
10051622
25704810
8630736
34162728
9188445
16497976
20841568
27602755
11598012
9326643
|
ABL1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
9525940
11494134
16713569
20841568
10829062
17389395
16955467
12604776
9890970
10391678
9195915
14725908
7925293
11997497
12522270
15556646
9102067
11239464
11994282
9174058
12475393
20675402
19380743
14604282
8626543
15212693
19823681
|
ABL1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
8978305
22581121
20841568
10837221
18768933
7493940
9710592
16955467
8524328
23331499
21199784
18794134
10592173
21051857
7926767
16443220
18835194
24165979
26500649
18809728
15459660
26192618
24412932
9053848
22286129
8083188
14604282
21435002
9820532
19823681
|
ABL1
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10837221
20841568
|
E2F1
|
APAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
11389439
11559530
11591730
15279786
17218262
17303408
17660363
18590585
7575488
|
E2F1
|
APAF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12766778
18524851
18951482
17600109
18093951
15972851
18056406
12149244
11389439
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
BCL2L1
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
10811864
9488720
12963020
9539746
|
E2F1
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11559530
12149244
18319725
11591730
11389439
|
APAF1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
17145710
15829969
15024710
9390557
19494828
11113115
10617566
9539746
10364241
10722681
27476169
21060833
19118655
20829884
16977332
10329646
15210107
10393175
16352606
11242052
14555243
10376594
12773388
10206961
19337385
10428850
9488720
19788417
15262985
9922454
21827945
10749135
9651578
19698783
12792650
9837928
11227497
|
APC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
APC
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
MYC
|
APC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22911891
12695333
|
AXIN1
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16199882
20128690
19131971
11297546
9554852
22682247
10228155
26496610
23277359
10811618
9734785
|
ATF2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9990041
10915780
11850817
11410592
11739785
15691880
16405968
10464245
10500157
15314161
10066798
|
ATM
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24357804
25545367
15916964
28212892
25689427
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
CDK2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
MSH2
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
AURKB
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22099307
27493659
|
ATR
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15510216
10608806
17478428
17124492
|
ATM
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
18662573
16122425
25077544
16122426
21113148
17525332
|
ATM
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20972224
11459832
27679857
15494392
15140942
27028861
21543892
27025900
20860841
24741006
17570479
25101673
28812991
15838517
22174788
|
ATM
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20471956
15494392
15140942
29590107
26170237
21108945
15838517
27220480
|
ATM
|
CCDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23108047
17420723
|
ATM
|
BUB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
22071147
27667906
24667671
25550082
22099307
22099300
17525332
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
ATM
|
FBXW7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17525332
26774286
|
PCNA
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
PCNA
|
ATR
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
MSH2
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
ATR
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
CDC6
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
CDC6
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
MSH2
|
ATR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19847258
16612326
14657349
16713580
20478261
15703371
18543256
12947387
19473888
19595721
19596235
18157157
16697054
19596236
18406444
21285353
|
ATR
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
26927092
17478428
24746700
15159397
17531442
10866324
18677104
19622404
15798197
19793801
20860841
16713569
11114888
23422745
20936109
16322207
19282663
20068231
17116885
17582221
25879655
10608806
17384638
23346553
12773400
12183412
17525332
15459660
11278964
17296725
11877377
17102137
10550055
16522651
|
ATR
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
22184068
11459832
15494392
15140942
26843428
27028861
20413589
27025900
24741006
23202967
25101673
27903963
27827925
15838517
22174788
|
BCL2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BAD
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
12107820
12175651
12444011
12767520
16931767
19030972
19641503
21540285
22039431
9346240
|
BCL2
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BAD
|
BCL2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
12107820
12175651
12444011
12767520
16931767
19030972
19641503
21540285
22039431
9346240
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
BAD
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
9305851
17145710
11483855
16697956
9463381
15694340
15849194
20603619
15990872
11583631
8929531
7834748
9388232
17446862
19168699
|
BAD
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
11483855
15694340
20603619
10381646
32296183
22000515
12115603
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
BCL2
|
BAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BID
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
23782464
17289999
11175253
10950869
12624108
23604079
12242151
|
BCL2
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
9463381
14980220
11206074
17289999
26004684
11728179
20836993
19168699
|
BCL2L1
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
22705850
9463381
22516262
31467278
32814053
9020082
23680104
34098062
18178565
15901672
16189514
17446862
20836993
23055042
19060904
17289999
32296183
10085290
14596824
15292519
29997244
31515488
11175750
9027312
|
BCL2L2
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17289999
18178565
25416956
10381646
15901672
32296183
|
BAK1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15901672
11571294
16189514
16439990
|
BCL2
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2L11
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10198631
12419244
15486085
15724238
23430059
23850759
9430630
|
TP73
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18034190
17346710
18421303
21245298
10559267
18418051
18644986
17521288
19067706
11748232
|
E2F1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9748148
11095619
12370749
14514686
15255934
|
NKX3-1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12203124
17213822
19801665
8183578
21594902
17486276
23291169
19266349
19242108
19054058
19136938
|
MYC
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8845569
11103792
12695333
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
AKT1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
26763134
14766748
15642728
17525161
|
BCL2L1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
59.0
|
1.0
|
Omnipath
|
22705850
18981409
21458670
28202514
11283018
17525735
29749471
21567405
9388232
18547146
19074440
16151013
21199865
18178565
26496610
16189514
15486085
26186194
17289999
9111042
12419244
25241761
14963330
12853473
9742125
9153240
19427863
21852238
14766748
21671007
15131699
9670005
8596636
24814347
9824152
9027312
|
CAPN1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20709625
21670566
21414921
16129881
17593948
14612448
21266584
|
BCL2L2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18981409
17289999
18178565
21199865
17452531
|
BCL2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
22705850
18981409
9463381
21458670
17097560
17525735
8358790
10620799
26004684
29749471
9388232
21199865
17525161
22262057
21778226
15486085
17289999
9111042
12419244
9194558
15231068
10716992
8183370
14980220
9115213
21671007
16642033
23479509
10677502
|
BCL2L11
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22492984
26186194
17289999
12419244
11301022
12198137
17525735
21199865
18948948
23235460
11997495
15486085
12242151
23374347
19427863
15721256
|
BCL2
|
BBC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BBC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
E2F1
|
BBC3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
14634023
14684737
15279786
17218262
17303408
17660363
18590585
7575488
|
MYC
|
BBC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12695333
12384701
19815507
20145032
21835778
|
TP73
|
BBC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15650240
19421143
18565851
15865927
17700533
18579560
|
TP73
|
BBC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11463391
19788416
11463392
14634023
14684737
|
E2F1
|
BBC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11463391
18319725
11463392
14634023
14684737
|
BBC3
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
|
BBC3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
19074266
28202514
15574335
|
BBC3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
11463392
|
BCL2
|
BMF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11546872
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10198631
11704864
15486085
15724238
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9430630
|
BCL2
|
BCL2L11
|
â—¼ PROTEIN_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10198631
11704864
15486085
15724238
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9430630
|
BCL2
|
BMF
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11546872
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
MYC
|
BCL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
NKX3-1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
12679484
15817464
17191317
22266868
22869582
24273454
21940310
8183578
23313858
9581775
14684736
24098340
17486276
19137013
19266349
16316993
22331597
|
MYC
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8036017
17404573
12695333
24167291
18809243
19201832
16316993
19649202
|
AR
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17655826
11567031
23160675
20610535
|
E2F1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17404573
11559537
12679318
|
CASP3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10409669
9395403
20139069
11948397
|
BCL2L1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18835031
14980220
26186194
11583631
|
AKT1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCL2L11
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
17145710
9463381
16697956
9430630
17074758
17097560
19805519
18498746
26004684
14517273
10198631
21199865
20836993
26186194
15694340
17289999
17692808
11301022
23845444
21671007
9731710
|
BCAP31
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9334338
17145710
|
BMF
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16697956
11546872
|
CREBBP
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9829964
10753867
17565603
15337521
10454566
|
AKT3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCL2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16183855
11406564
|
BCL2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18835031
17145710
9463381
16697956
17289999
19074266
12624108
11583631
9727491
15520201
8918887
|
NKX3-1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22869582
19439449
23677993
21354697
11450946
16316993
16214938
|
MYC
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14517295
18802399
16316993
17331788
|
BMF
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
26871637
16697956
15694340
11546872
25416956
32296183
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
BCL2L11
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
17145710
16697956
9430630
17525735
22516262
18498746
10198631
21199865
20836993
26186194
15694340
17289999
27013495
32296183
23245996
11859372
19427863
21671007
14596824
9731710
16260615
|
BCAP31
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9334338
17145710
12594175
|
BID
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
9727492
19074440
16697956
15694340
17289999
25241761
22464442
14963330
16189514
27159560
24814347
15574335
|
BCL2L1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
25241761
9539746
|
E2F1
|
BCL2L11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11050388
11301023
11495903
14684737
15279786
17218262
17303408
17604722
17660363
18281283
18590585
19494111
7575488
|
E2F1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17604722
11495903
11301023
18319725
19494111
11050388
18281283
14684737
|
AKT1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17145710
16282323
30923040
|
BCL2L11
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
9430630
16697956
15694340
17289999
21199865
9731710
32296183
|
BMF
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
25416956
32296183
11546872
|
BID
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
16697956
17289999
15694340
|
BID
|
HSP90B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
14687661
18360008
23430059
23850759
|
BID
|
HSP90B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
14687661
18360008
23430059
23850759
|
E2F1
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12402042
15024076
15240700
15279786
17218262
17303408
17660363
18590585
7575488
|
CAPN2
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
21887410
23242420
|
CAPN1
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
19931333
|
CAPN2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18469004
12000759
20709625
17264306
21670566
11404357
21738214
16129881
17593948
21266584
11940658
|
CASP3
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
11085742
11085743
|
CASP8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
12196516
18458084
9727491
11085742
11085743
12097160
9873064
|
CSNK2B
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11583622
|
CAPN1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18469004
12000759
20709625
17264306
21670566
11404357
21738214
16129881
17593948
16189514
21266584
11940658
|
PCNA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
E2F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
BRCA1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
PCNA
|
BRCA1
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
E2F1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
E2F1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
BUB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
BRCA1
|
AURKA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
E2F1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10660629
23285190
18660752
19466541
17106239
20068145
23108140
|
MYC
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12032322
19882681
20940401
10375022
21668996
11916966
12646176
11983916
|
BRCA1
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17428466
11777930
10962562
18025037
18350249
12647291
|
BRCA1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9926942
11394910
10196224
18025037
21245169
16735508
12647291
|
E2F1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9244350
18660752
18319725
11278247
12697828
16713569
12909625
|
CDK2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8764100
10373534
10550055
19683496
16713569
26719576
15212693
|
AURKA
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
22864622
22340593
18026198
24775809
14990569
|
AKT1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17428466
20832017
20085797
21242970
17570479
10542266
|
BRCA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11085509
16713569
11016951
|
BRCA1
|
GADD45A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
12771027
9346961
10779360
11877377
10367887
19004803
21060331
12496474
19793801
15650754
10962562
21337561
9892649
10528224
15459660
20029420
|
PCNA
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
NKX3-1
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21850191
15705778
24961145
20599703
|
BIRC7
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23563149
11024045
17145710
11084335
|
CASP10
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11717445
8755496
9765224
|
BIRC3
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9990849
12042762
9384571
17069460
|
E2F1
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18660752
12389032
18319725
|
BIRC2
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
9990849
12042762
9384571
17069460
11382748
11106668
16189514
11084335
|
CASP8
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15755874
17179148
9501089
9950028
18669646
23308069
10988287
18458084
16964285
9885230
9765224
11437602
15014070
21295084
8962078
9208847
|
BIRC5
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
9384571
11024045
9850056
10587640
16189514
16540654
|
CASP9
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10708865
9390557
10508159
11230124
18723680
15657060
16977332
15507451
1067155
9708736
25241761
8900201
11242052
9765224
17437405
19788417
9812896
12620238
15941357
12181739
19465923
12792650
15725726
|
CASP3
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8626669
9535906
16713569
9208847
|
CASP3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
25241761
9660939
10022118
9799125
|
CASP3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17544405
12124386
10579725
|
CASP7
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
16916640
9922454
11752425
11701129
12824163
|
BIRC5
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
11069302
25241761
11024045
16189514
12773388
10329646
15210107
|
BIRC7
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
11024045
11801603
25416956
31515488
32296183
11084335
|
AKT1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20398329
18372248
15004527
15808505
20138985
20214616
15703181
17570479
28177918
18840507
15169778
11714830
10949026
16341064
11715018
18636226
10529400
9812896
17680028
19440551
10722653
20832730
18570873
17052453
|
AKT2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9812896
15004527
|
AKT3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9812896
|
BIRC3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
16339151
21988832
9990849
15069192
25241761
9545235
16701639
|
BIRC2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
16339151
9990849
15069192
25241761
19153467
9545235
25416956
31515488
16189514
32296183
16701639
11084335
|
CASP9
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17899380
9922454
16352606
9598997
9651578
|
CRKL
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
MYC
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7526316
21933022
17881732
12835716
14757441
19086036
8552398
19698176
19786833
18809243
18806825
8196642
11085504
|
E2F1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10504464
7929342
22768064
19876926
20220142
9584162
17998543
20655656
8618861
8137237
23078099
23543735
10594784
|
FOXM1
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16585184
11572993
10567581
11391529
|
EP300
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17306568
17666529
11788592
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
CDKN1A
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
26203195
23443559
17145710
25416956
7478582
9837900
21988832
21516116
7777546
15232106
16082198
27107012
15695403
8657154
8242751
23007395
9106657
12383116
17556661
8756624
8662825
31515488
|
CDC25A
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
18073536
1075565
17568790
18786381
17660363
15279786
|
MYC
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8425218
15121849
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
CCND1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
9190208
10498883
18590585
7575488
9315635
17303408
10385618
10778858
9736735
16236519
20068082
7736585
9425340
11520855
19075565
18786381
17660363
15279786
|
CCND1
|
RBL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16600870
10498883
10385618
9736735
12006580
|
CDC25A
|
CDK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
1075565
15279786
17303408
17568790
17660363
18073536
18590585
18786381
7575488
|
E2F1
|
CDC25A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11154267
11799067
19633359
|
MYC
|
CDC25A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8994810
10205150
11154267
9371770
14519204
15677471
17671423
|
BTRC
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19847258
14603323
15340381
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
FOXM1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15689977
11572993
11391529
16314512
|
MYC
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8425218
15121849
11602341
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
CDC25A
|
CCNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
18073536
10926775
1075565
17568790
16189514
18786381
17660363
15279786
|
CDC25A
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
8617791
11602341
17303408
18073536
1075565
15279786
7575488
10454565
11154267
12411508
16189514
1396589
18590585
18786381
17660363
12388094
22263797
27485204
17568790
15659558
|
CDC25A
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
8617791
17303408
18073536
1075565
17568790
18786381
17660363
15279786
|
CCNE1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CCNA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
MYC
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CCNA1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16189514
15583032
25241761
16777603
10559988
14681455
9636170
16159883
9041194
10652300
8565853
12970441
14701826
8397206
14681231
11264176
8397207
15601848
12191604
12190313
7799941
19423708
12800980
16009130
|
MYC
|
CDK2
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
E2F1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
12086603
14536078
14988723
15136767
15147722
15175241
15279786
15798197
16713580
16805667
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18469862
18590585
18636226
18995830
19282663
19342888
19622404
19793801
20051983
7575488
|
CDK2
|
CDC6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
AKT1
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18354084
29665367
|
CDK2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8386367
27653698
17081983
19966300
18669648
29896817
17570479
20713526
17558397
15103331
22348395
20445224
|
CDK2
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22002055
15985436
12676926
|
CDK2
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20935635
25800736
29576612
23241245
32368395
29556394
17570479
27863310
26279746
|
CDK2
|
CCDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17570479
14712216
|
CDK2
|
RBL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
20857408
17570479
11042701
9188854
11157749
12006580
15212693
10825149
|
CDK2
|
FOXM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
28387346
15024056
19737929
|
CDK2
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
7575488
18590585
9315635
17303408
17570479
25101673
16213134
17660363
12006580
11420722
15279786
|
CDK2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
94.0
|
1.0
|
Omnipath
|
23443559
23455922
10878006
20100570
23602568
15964852
20839231
25416956
23737759
9840943
18850315
11302688
20519948
24358021
19440234
15557281
9472014
9658399
16962592
9736735
12949733
8641969
10022118
15890360
12839982
16765349
17418410
15647383
10874474
15232106
17570479
17698606
12361598
26496610
9632134
24419005
12417722
16189514
26186194
20587660
25241761
8622677
9660939
25483090
12800980
20102411
10918595
12058028
12144826
8242751
9464540
9858587
29899857
23007395
11477082
9218599
12383116
25463440
12730199
8756624
9284049
9380407
9546435
24218572
16964243
15212693
13678583
|
CDK2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
81.0
|
1.0
|
Omnipath
|
8756328
7553852
11377199
17145710
23602568
11983168
12044161
19483727
12853968
16209941
8397207
15455144
19631451
8475101
24358021
15557281
8684460
12941338
15647383
15890360
21447625
9380407
26496610
11141566
25852190
15189033
14656438
20733051
21241890
10652300
25669885
12244298
26186194
10930425
9660939
10477583
24302728
15239650
19773423
8463339
16290148
10924145
11907280
17361108
17254966
8662825
15828833
18471975
9724724
7630397
10559988
9716181
11940657
23455922
|
CDK2
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
17303408
23129444
19793801
15279786
7575488
20068231
17116885
17582221
17570479
9889196
27207654
16153703
18590585
29760377
18691976
10339564
14749377
19343071
17660363
16707497
17296725
24216307
23479742
17102137
15212693
|
CDK2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
17145710
16223725
21092281
15004009
10962581
9840943
8643455
24358021
8861947
21372285
17570479
11237742
10330164
22558078
10652300
19561641
10477583
18691976
23853094
12144826
10500095
1388288
10827081
17970072
28137908
19470470
8756624
10809788
14536078
15364936
|
CDKN1A
|
CDK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23443559
26186194
23602568
24218572
32296183
7626805
9811456
|
E2F3
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17008321
10030670
22894933
17167174
15855772
|
AR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16281084
10076995
11606392
10606230
20610535
10809237
|
EZH2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21572997
21546904
24074410
21629038
22956625
|
MYC
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15190211
14519204
15616584
12408868
19174556
21949397
10319992
12553001
16204065
12545156
20878079
21042278
21400515
20190815
16706751
23804320
15757889
10920185
19270520
16452181
12408820
15528212
22371483
12565816
17885207
12384701
11274368
19150257
20551174
15899785
21120446
15071503
15474507
22814619
12835716
12748190
16738884
15711923
18636159
|
E2F1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9748148
9191053
16923815
17008321
10030670
10702805
15048076
17167174
|
HDAC1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12665570
19182791
15130752
18210215
16287849
17172847
|
FOXM1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16314512
20887555
23804320
17101782
19097132
|
TP73
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10435630
15790310
11172610
17611664
12934105
18421303
21245298
18418051
12841870
14614455
12639967
10207112
17700533
18644986
18951877
19067706
16193303
12676926
|
EP300
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10362258
15509808
21858218
22000024
21245169
|
CUX1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11584018
12438259
15812824
15269344
|
AKT3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12851486
15023346
19216069
17680028
11756412
16680151
20214616
11463845
23109003
20452955
9829964
20398329
17646672
10217147
|
AKT2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
21933447
16982699
20452955
9829964
20398329
17646672
10217147
|
MYC
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15528212
9618481
12545156
17550342
10454538
15155580
11283613
10920185
11283614
|
AKT1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20452955
27603133
20398329
18372248
15001356
15808505
10217147
19440234
20138985
12431783
10753973
17855660
19216069
28358423
20214616
11463845
9829964
17570479
17646672
16680151
11231573
15169778
12851486
31575057
25241761
23109003
21933447
10949026
16775416
23886938
26436589
16288292
11715018
16055744
18636226
15023346
9812896
12042314
17680028
24848107
16982699
11779850
10722653
20832730
18570873
20307683
34069970
17052453
15798220
|
CDKN1A
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
23443559
26186194
25241761
27107012
8756624
15169570
25416956
16765349
31515488
16189514
32296183
|
CDKN1A
|
CCNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12383116
25241761
8756624
29997244
16982699
7478582
10022926
32814053
15232106
16009130
16189514
|
CDKN1A
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
67.0
|
1.0
|
Omnipath
|
23443559
25411249
20606006
8868473
15576034
16474839
25416956
20605778
16510448
18703516
23139781
11302688
11254741
26272819
16616141
21988832
11313979
7780738
17588519
12964161
25502805
10022118
8861913
16189514
26496610
16082198
8861969
17129767
18263614
26186194
22383522
22911014
7915843
7911228
27107012
23223023
17115032
32296183
19895794
18794347
19704162
10873631
9546435
8662825
31515488
21415862
9545252
11350925
12930846
|
CDKN1A
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
21988832
23443559
26186194
25241761
27107012
8756624
25416956
16328436
31515488
16189514
15232106
32296183
23880157
26496610
9716181
|
CDKN1A
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
23443559
26186194
21308745
9660939
8756624
15890360
9380407
8242751
8662825
12947099
9632134
17679094
26496610
|
CDKN1A
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
9190208
10498883
18590585
7575488
9315635
17303408
10385618
10778858
9736735
16236519
20068082
7736585
9425340
11520855
19075565
18786381
17660363
15279786
|
CDKN1A
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
23443559
26186194
28514442
9840927
9840943
15232106
26496610
24358021
|
CDKN1A
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
23443559
31831640
21988832
9472014
17293600
11438644
9380407
12839982
16765349
9632134
25241761
8891332
9660939
8242751
9218599
11477082
8756624
8662825
8637717
9716181
13678583
|
E2F1
|
AXIN2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15279786
15766563
17218262
17303408
17660363
18590585
22699938
7575488
|
E2F3
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14576826
7958836
12063292
|
E2F1
|
CDC6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11799067
18541154
12411495
19633359
|
E2F1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21411498
22654424
18818403
11433024
19358274
22207128
16264179
12368233
|
E2F1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
7623816
12782299
14618416
20580656
9389735
11133765
8903355
9649317
23078099
12468739
1261188
|
E2F1
|
BIRC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23449974
19497660
15271987
16601104
17848598
19102934
|
E2F1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
21966451
17178887
22508987
21099110
21099103
|
E2F1
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7623816
11264255
9178900
20580656
14681231
10594784
24335704
|
E2F1
|
CCNE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
21653699
19564413
20220142
23518498
8668155
7623816
1059478
14618416
20410059
12565705
17471231
23543735
10594784
24335704
22185819
21454377
11526499
10504464
8618861
8649818
|
E2F1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8208548
2721961
7753559
11705881
24038073
8355712
1549358
1567856
12629508
|
E2F1
|
TP73
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12766778
11101847
11988839
14602923
18660752
19188449
18029729
18521084
15210709
11115495
17980704
19363520
12789260
21310950
22952705
|
TFDP2
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
26186194
9704927
9368098
8755520
9501179
7739537
|
CCND2
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
9190208
10498883
18590585
7575488
9315635
17303408
10385618
10778858
9736735
16236519
20068082
7736585
9425340
11520855
19075565
18786381
17660363
15279786
|
CCND3
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
9190208
10498883
18590585
7575488
9315635
17303408
10385618
10778858
9736735
16236519
20068082
7736585
9425340
11520855
19075565
18786381
17660363
15279786
|
CCNA2
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15840440
16135794
9736735
15133492
15558010
15123636
9556498
12501191
16213134
11980909
16123593
|
CCNE1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
7575488
18590585
18687693
9315635
17303408
17660363
12006580
11420722
15279786
|
CREBBP
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10753885
15126619
12748276
15123636
8932363
|
CCNA1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
17660363
15840440
16135794
18590585
7575488
17303408
9736735
15133492
15558010
15123636
9556498
10022926
16213134
11980909
16123593
11739724
15279786
|
E2F1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15210709
11988839
17488475
11937641
|
E2F1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15572025
18319725
22699938
17218262
15766563
|
E2F1
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18660752
12389032
18319725
|
E2F1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15510213
18319725
11491305
|
E2F1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15510213
7575488
18590585
17303408
18319725
17660363
15279786
|
E2F1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18319725
14532106
|
AKT2
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17964260
16926151
|
PCNA
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18263614
11268218
16713569
|
AKT1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17623675
18182168
16926151
20333651
19158375
17964260
17570479
11116148
25904863
21901101
23275565
16024795
|
EP300
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11971970
10779504
24480624
17011549
16713569
|
EP300
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
11804596
19407812
15175157
19788416
12660246
19218448
10648616
15454570
16998810
25675294
15893728
18663001
|
EP300
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
FBXW7
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
12824889
11565034
17646408
17298674
11565033
19956254
18559665
17434132
22388891
28209614
11533444
15980150
16338364
16818231
21070969
24298052
14536078
15364936
|
FBXW7
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15498494
17145710
32047362
28007894
31569395
33821962
20399964
20970423
17157259
16023596
20852628
15103331
15150404
|
MYC
|
FOXM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20658516
18798339
12695333
17341548
|
FOXM1
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11572993
19276163
15671063
11682060
19097132
23812424
|
FOXM1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15817462
15689977
10567581
11572993
11682060
15024056
11391529
|
FOXM1
|
AURKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15817462
15689977
17173139
16314512
|
FOXM1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17141659
10567581
17655499
16965535
11391529
|
FOXM1
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17018632
17173139
16314512
17408638
|
PCNA
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10779360
11756412
12124778
14624239
14726013
15703371
15917306
16697054
17599061
19004803
19652693
1974050
19847258
20457011
22021614
22615860
23414611
23485469
|
PCNA
|
GADD45A
|
â—¼ PROTEIN_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10779360
11756412
12124778
14624239
14726013
15703371
15917306
16697054
17599061
19004803
19652693
1974050
19847258
20457011
22021614
22615860
23414611
23485469
|
PCNA
|
GADD45A
|
â—¼ REGULATES
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10779360
11756412
12124778
14624239
14726013
15703371
15917306
16697054
17599061
19004803
19652693
1974050
19847258
20457011
22021614
22615860
23414611
23485469
|
MYC
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15721278
9190899
10913183
15021909
14519204
9811446
21835778
|
GADD45A
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10367887
21614932
12738796
11274345
18855897
|
GADD45A
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7784094
23485469
10973963
7973727
10828065
16189514
20460379
7478510
|
PCNA
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20154325
22118461
11274057
23840062
|
MYC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
AXIN1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
MYC
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8386381
10713672
12835716
7608142
12937171
14519204
14729654
|
MYC
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7597041
18358094
22911891
18809243
1280813111085504
11085504
|
MYC
|
CASP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15367674
12695333
|
MYC
|
CCNE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18802399
20607601
14519204
22583478
9188852
11983916
11509615
|
MYC
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7526316
11511535
10508165
9339900
15988028
20857481
11060032
14519204
14660677
10956386
21790895
11264343
|
MYC
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23135913
19578399
12695333
|
MYC
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12747840
11522645
11983916
19470724
|
MYC
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
76.0
|
1.0
|
Omnipath
|
16287840
15655249
12821782
16880523
21807113
19047367
14744757
16489011
12941894
10786671
14519204
19360348
10723141
12970752
15595642
18365874
15665468
22207128
14611815
10022128
15226182
11274400
10491298
11606399
17070091
19787269
19806010
20454512
19762557
21132266
21553143
18818322
10914736
17934056
19148473
11435602
12695333
12802280
21995449
11287602
12044867
21627565
23860446
17942561
19649288
23759068
10606235
12807729
15958520
17141225
20723213
16402390
16785237
18093727
21855630
24705139
18367227
14563552
16205635
19003324
9988278
17706770
17967894
18226852
18754863
10637317
18586674
14612409
19912441
15371341
11916966
12646176
11279234
18158869
|
MYC
|
ATF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12695333
23612979
|
MYC
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20890087
20519624
14744757
20682043
|
MYC
|
BIRC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17170079
19287963
20508797
19602047
|
CREBBP
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
15522869
12776737
20144767
17660363
16878156
15279786
|
HDAC1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
MYC
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8425218
15121849
11602341
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
NKX3-1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18360715
20363913
23492366
17202838
16697957
|
TP73
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15734740
22496369
16234237
16205639
|
AKT1
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
25999477
22366458
10224060
17570479
22902867
15843522
18775701
|
TP73
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10648616
21245298
11172610
10435630
|
TP73
|
CDKN1C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16405903
18513743
17045206
11891335
15985436
|
E2F2
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15510213
18319725
11491305
|
ATF4
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11564156
9295363
25241761
|
CCNE2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
CCNE1
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
HDAC1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
CALM3
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
AKT1
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25241761
10490823
25814554
12621049
|
CALM1
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17145710
3006921
17353931
20668654
|
CRKL
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
BCR
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26500649
8978305
15143164
|
CALM2
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
PTEN
|
AKT1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
22.0
|
1.0
|
ACSN
|
10753747
11747822
12040186
15721744
16288286
16982858
17218262
17409395
19440036
19847259
19945467
20609352
21084277
22179046
22465479
23732914
24030100
24254977
25364523
26597054
27328425
27572739
|
AKT1
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19903340
15987703
10790335
20596030
10592173
20605778
10866658
12077256
11035045
16107342
12297295
|
PTEN
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15205473
24480624
|
HDAC1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15465827
17018611
17563753
21234400
21577210
21685935
22514743
22796940
|
HDAC1
|
EZH2
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15465827
17018611
17563753
21234400
21577210
21685935
22514743
22796940
|
HDAC1
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
22.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
15151915
15155580
15465827
16232121
17055429
17508028
17550342
20027199
20713526
20818389
21234400
21733352
2191300
21919891
22370643
22796940
23140366
23869868
9618481
|
HDAC1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11994312
16713569
15640443
12612053
10428808
|
BUB1
|
BUB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10477750
11402067
11535616
12640463
15024386
15279786
15592459
17303408
17376779
17498870
17660363
18022367
18590585
19154723
19182530
19503101
21270334
23197039
7575488
8824189
9790499
|
BUB1
|
BUB3
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10477750
11402067
11535616
12640463
15024386
15279786
15592459
17303408
17376779
17498870
17660363
18022367
18590585
19154723
19182530
19503101
21270334
23197039
7575488
8824189
9790499
|
BIRC5
|
BUB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
AURKB
|
BUB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
BUB1
|
BUB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21988832
26186194
26148513
20220147
20057499
25416956
16760428
26496610
11283619
11402067
16189514
9660858
|
BIRC5
|
AURKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
BIRC5
|
AURKB
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
AURKB
|
BUB3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
AURKB
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
17145710
23955284
21554500
16291752
18477699
12419797
27332895
19357306
14610074
20807437
17457057
29371939
17099693
11516652
24571573
17681274
21051298
19995937
16769825
20430883
|
BIRC5
|
BUB3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
BIRC5
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9384571
11024045
9850056
16189514
11170436
|
AR
|
CDC6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24583551
18541154
19520769
20610535
|
CCNA2
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9889196
10339564
9566895
|
CCNA1
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
17296725
17303408
17102137
17116885
19793801
17582221
17660363
15279786
|
BCAP31
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
9334338
17145710
12668660
|
CASP8
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18073771
9545235
10872455
18329793
9727491
9463409
|
CASP8
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17170703
9535906
16713569
|
CASP8
|
CASP10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
22864571
17159907
17145710
12887920
11832478
11717445
21737330
15280356
12198154
3031469
15659383
170210
8962078
22421964
|
CALR
|
B2M
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
14508489
16181333
16239148
17204652
20958319
22076556
23157435
23850759
|
CALR
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8107809
16713569
|
ARNT
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
11959990
11063749
7836384
11959977
9632793
17804822
9822602
10202154
|
AR
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9822653
15350180
16492776
16344550
11161315
18819102
18031230
20610535
|
CREBBP
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20541699
9822653
15691881
12810069
9482849
16713569
|
BCAP31
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
2038058
19851281
16473882
21050182
17656363
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
AKT1
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22505453
23092893
|
AKT1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
15911620
15998799
17570479
30680530
11707464
|
AKT1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
19651622
20058876
14688280
11510412
25241761
20230923
20068231
18452278
11410590
17570479
10869359
18669648
|
AKT1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
22391560
24526064
29864144
34230470
16224021
26517694
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
AKT1
|
CDKN1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12925736
23421998
|
HMGA2
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17324944
21566082
17005673
14645522
|
PKMYT1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
9001210
12814430
10373560
18319725
12738781
26496610
23397142
10504341
|
CDC14A
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
CDC14A
|
CDC26
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
20144767
17660363
15279786
|
BIRC2
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16339151
9384571
16189514
11084335
|
CCND2
|
RBL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10385618
9736735
12006580
10498883
|
CCND3
|
RBL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
16600870
10498883
26186194
10385618
9736735
12006580
|
CDC27
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
ANAPC5
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
CDC16
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
CDC26
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
ANAPC7
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
CDC23
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
E2F2
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15510213
18319725
|
E2F3
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15510213
18319725
|
ANAPC4
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
ANAPC1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
ANAPC11
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
ANAPC10
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
ANAPC2
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
16123593
15279786
15917306
|
E2F3
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15510213
11980909
10733529
18319725
|
NRAS
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
1386920
21478863
9368069
19541618
8601312
14970219
18567582
16135787
7935411
12932319
12917261
17563371
19933846
21779497
8073291
15710605
|
AKT3
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10869359
18451171
11293329
19493313
|
AR
|
ANAPC10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
CASP7
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9535906
16713569
|
ANAPC2
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10922056
10500174
|
ANAPC10
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11524682
10500174
|
CDC16
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17145710
9405394
17187060
24100295
7736578
21043528
10922056
26496610
9356466
25306918
12956947
20733055
22193957
27114510
16648845
9628895
14657031
20360068
16364912
10500174
|
CDC27
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10922056
10500174
|
CDC27
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17145710
9405394
17187060
24100295
7736578
21043528
10922056
26496610
9356466
25306918
12956947
20733055
22193957
27114510
16648845
9628895
14657031
20360068
16364912
10500174
|
CDC27
|
ANAPC10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11524682
10500174
|
ANAPC10
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ANAPC2
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ANAPC11
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12956947
24163370
11739784
10230407
|
ANAPC2
|
ANAPC11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12956947
24163370
11739784
10230407
|
CDC26
|
CDC16
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21988832
20360068
25416956
25723520
31515488
26496610
32296183
19668213
|
CDC16
|
CDC26
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21988832
20360068
25416956
25723520
31515488
26496610
32296183
19668213
|
ANAPC4
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ANAPC10
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
HSP90B1
|
TLR9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
22223641
18509083
20865800
8344253
19965672
17275357
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
EZH2
|
RUNX3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18430739
22222375
20631058
|
E2F2
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18319725
14532106
|
ARNT
|
AHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
8621524
8384309
9887096
20006590
10395741
18096572
12024042
7628454
9704006
19380484
17823304
11259609
19390533
22138065
8631989
8619634
8065341
11768231
7488247
|
AIP
|
AHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
9111057
10986286
11013261
16257957
9083006
16582008
12065584
9837941
7961671
|
BIRC3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16339151
9384571
|
BMP4
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8702914
23331499
21071413
16446785
12045205
8006002
7673243
7644468
|
BMP2
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10880440
23331499
11263668
23180781
18342887
16446785
10880444
10712517
7791754
17295905
25938661
24337809
|
NRAS
|
FGFR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
RBL2
|
E2F5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16600870
17531812
11756542
7760804
15838517
|
TFDP2
|
E2F2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8755520
7739537
16189514
|
CAMK2G
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
9768837
8798667
|