Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XIAP NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NTAQ1 XIAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TLE5 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20676368
DIABLO BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10929712 5212852
XAF1 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17613533
CASP9 BIRC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11024045 5213055
UBE2K BIRC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
XIAP CASP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547707 9525868
CASP9 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
XIAP CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242052 5213680
CASP9 DIABLO â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14960576 11084335
XIAP CASP9 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CTNNB1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17000761 15729346
UBC TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218828 16845370
XIAP TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBE2D1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22842904 21857666
USP2 UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
BIRC2 HTRA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BIRC7 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
NTAQ1 HTRA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XIAP CASP3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9525868 6547707
UBB UBE2D1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBC XIAP â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
BIRC7 IKBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC7 Z3H7A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC7 CLCN7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC7 DHRS4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC7 OSTM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC7 XIAP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 22711539
BIRC7 PCNT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XAF1 XIAP â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
BIRC2 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CLCN7 OSTM1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
UB2D2 UBB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 30523153 26186194
CASP9 CASP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1067155 11242052 11230124 18723680 25241761 15941357 17437405 8900201 15507451
XIAP UB2D2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29020630 12525502 27569044 25801170 19549727 21113135 23259674 11724934
BIRC7 XAF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17613533 32296183
RAF1 XIAP â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
PSMB1 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMB1 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
BIRC2 NTAQ1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781
BIRC7 BIRC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 22711539 21113135 26186194 25416956
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBE2D1 XIAP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BIRC2 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
TAB1 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
HTRA2 DBLOH â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11606597 11604410 16713569 32877691 16189514
UBE2D2 XIAP â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BIRC7 DIABLO â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
UBB USP2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CASP7 BIRC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 9384571 15580265 19258326 16339151 11084335 16189514
HTRA2 BIRC7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194 11801603
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
BIRC2 DIABLO â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 12525502
BOLA1 XIAP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
UBA1 UBE2D3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
VPS37C XIAP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BIRC2 UBE2D1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
BIRC7 UB2D2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21113135 16729033 22902369
BIRC7 DBLOH â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11801603 22902369 26412467 26186194 12620238 28514442 16729033
DBLOH BIRC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 12525502 25065467 27476169 19506082 20957035 30359437 10929712 19153467 14960576 12218061 16282325 12865429 25246529
HTRA2 BIRC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11583623 33961781 16189514 31617661 16713569 11604410 28514442 12865429
CASP3 DIABLO â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14960576 11257231 9230442
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
MITF CLCN7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19067971 1999537 17105730
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
BIRC2 CASP9 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
UBB UBE2D2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
UBA1 UBE2E1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HTRA2 XIAP â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
XIAP DIABLO â—¼   UBIQUITINATION ✅ - 0.91 0.91 Signor 15749826
BIRC2 DIABLO â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
BIRC7 UBC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
XIAP CASP3 â—¼   UBIQUITINATION ✅ - 0.94 0.94 Signor 11447297
UBA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBA1 UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
UBB UBE2N â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
UBA1 UBE2K â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
UBB UBE2K â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
OSTM1 CLCN7 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 16525474 32749217 32851177
XIAP HTRA2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24698088
HTRA2 XIAP â—¼   PROXIMITY ✅ 0.96 0.96 mint 31617661
BIRC2 UBC â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
BIRC7 UBE2D2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBE2I UBE2K â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
DBLOH XIAP â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 11801603 21185211 14512414 15178455 11604410 27927753 17724022 15781261 25246529 11140637 22465666 14523016 11606597 11257230 15541727 16282325 32877691 15300255 12525502 11257231 19667203 27476169 12511567 23818254 19153467 19506082 28514442 32447208 16189514 11140638 29678905 12660240 11242052 11602612 15200957 15650747 25801170 17179183 15280366 20957035 23251006 34247143 10929712 12218061 31699976 15507451
BIRC2 UBE2D2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CASP3 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP9 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP7 XIAP â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
UBC USP2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
DIABLO XIAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
UBC UBE2K â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
DIABLO BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 18022362 11606597 10929712 12218061 12865429 10929711 19153467 27476169 14960576 25246529 12525502 20957035 18485876 16282325 19506082 25065467 18022363
HTRA2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11604410 12865429 11606597 16713569 11583623
BIRC2 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 9990849 12042762 9384571 17069460 11382748 11106668 16189514 11084335
BIRC2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 16339151 9990849 15069192 25241761 19153467 9545235 25416956 31515488 16189514 32296183 16701639 11084335
BIRC2 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16339151 9384571 16189514 11084335
MITF BIRC7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19067971 1999537 18451137 23480510
BIRC7 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 11024045 11801603 25416956 31515488 32296183 11084335
BIRC7 DIABLO â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 26186194 12620238 22902369 11801603 26412467 15485396 16729033 19284370
BIRC7 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23563149 11024045 17145710 11084335
XIAP CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 23074197 16543147 22072751 12624662 18521960 22815893 11157976 15650747 15200957 11927604 11230124 9384571 16869888 9545235 23979166 18723680 16189514 11359776 15507451 9230442 19273858 26186194 10508158 25241761 12529384 19559631 11257230 12874265 9525868 17291493 11583623 11257232 17069460 12181739 10548111 11447297 15014070 19698783
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP7 DIABLO â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14960576 11257231 18619610 9230442
CASP7 CASP9 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 16916640 9922454 11752425 11701129 12824163
CASP9 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17899380 9922454 16352606 9598997 9651578
XIAP CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 11447297 11257231 18521960 31467278 15200957 9384571 9545235 14512414 23979166 16189514 11359776 9230442 10508158 19559631 11257230 9525868 11583623 15580265 11257232 23074197 19698783
XIAP CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 15069192 15280366 25416956 18022362 11157976 31467278 15200957 11927604 11230124 12042762 16322207 9545235 11801603 25502805 14512414 16189514 15300255 15507451 10508158 25241761 27107012 14523016 17179183 16352606 11242052 32296183 16701639 17291493 12620238 15749826 12181739 11390657 29997244 31515488 23074197 19698783
XIAP DIABLO â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 10929711 11140637 15078891 17435549 22733138 23070005 26587781
DIABLO XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 82.0 1.0 Omnipath 17686459 15280366 11257231 11157976 11606597 15650747 10929712 11927604 12218061 15200957 15541727 12865429 10929711 11801603 14512414 27476169 15178455 16189514 25246529 15300255 15507451 11140637 11604410 11140638 15078891 14523016 12525502 20957035 12660240 17179183 25801170 11257230 11242052 23251006 23818254 11801595 16282325 19506082 31699976 12511567 17724022 11583623 11602612 22465666 21185211 15749826 15781261 12181739 19667203 32447208 12121969 10972280
HTRA2 XIAP â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10521396 11583623 11803371 12815069 12835328 15781261 19935698 20125124 23070005
HTRA2 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12835328 11606597 16713569 12815069 28642151 17311912 15200957 17906618 11803371 29631059 12865429 11801603 15201285 15300255 11604410 11583623 11602612 15781261 24698088 31470122
UBE2I MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10673502 16713569 10694430 16029420
RAF1 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16964381 19011619 25241761
XIAP TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9878061 12048196 17560374 27107012 11865055 23818254
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
XAF1 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 23323858 11175744 22811387 17613533 12766484
XIAP XAF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11175744 17435549 22733138 23070005 26587781