Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 SOS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 DNM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 NPVF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JUN ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
MYC BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16169462 21899728
MYC BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12209154
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
CREM CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22488648 17185632
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
MAPK1 PPP2R5C â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16456541 5218298
MTNR1A MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18930812
NR1H3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10890879 12551904
MYC PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19602047 11509615
MYC SLC2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10823814
MYC ADM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9973255 15192039
MYC RPL23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14519204 11085504
MYC RPS20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11085504
MYC RPL32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916 11085504
MEF2A MYH6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15737621 9111345
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
GNA14 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3R1 SOS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 JAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 GNA11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3R1 GNA15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3R1 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
AR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12933816
FZD7 ADCY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AR CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16619263 20610535
CALM1 ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16258073 10075700
CALM1 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
ADRA2A GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 1849000
BDKRB1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11713280 31160049
GNAI3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8327893 19703466
PLCG1 EPOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
PLCG1 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9516477 6730883
PLCG1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
EPOR PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15953601 15329338
PAX8 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
AGTR1 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
JAK1 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK1 CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
STAT6 JAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22254182 17433443
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
SMAD2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21836474 21926264
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
SMAD3 ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20123992 12702545
SMAD3 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14623893
JAK2 STAT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15261459 23124025
JAK2 CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK2 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
STAT6 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27861999 23184467
JUN VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15930183 17121851
JUN AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
JUN CREM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21757709
JUN IL5RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9742933
JUN PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
JUN CGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15961508
PPARG ACE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18344629 20613959
PPARG IL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19307774 11093153
PPARG CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21690289 12813462
PPARG NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
CDC42 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10934474
AR CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24218937 20610535
PPARA CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20146263 15314095
ELK1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17505916 23818898
ADAM17 TGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26284334 11823465
ELK1 MYLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16260603
AR PRKD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18602367
KLF4 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22677193
KLF4 ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16858008 10954723
GNAI1 GNG2 â—¼   PROXIMITY 2.0 0.8 intact 8189321 21552208
GNA14 GNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNB3 GNA11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNB3 GNA15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
ADRA2A GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 11732925
HTR2A GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11916537 31160049
GNAI1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15922020 19703466
RPL36 RPL18A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPL7A RPL36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ADRA1A ATP6AP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
MAPK11 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9776729 11604491
AR ADORA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16987234
AR CHRM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11884637 20610535
AR VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15805579 16425262
AR ADM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16376459 20610535
AR SLC2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17426252 20610535
AR ADRA1D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16964290
AR ADRB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9855630 20610535
ADRB2 ARRB2 â—¼   COLOCALIZATION 2.0 0.8 intact 23208550 8428323
ARRB1 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219925 17498700
ARRB1 AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11579203 17498700
ARRB1 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16407241 11171997
GNA14 GNA11 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA11 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
HTR2B GNA11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11916537 8621713
NR1H3 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17054913 22279938
S1PR4 GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 12767884
PPARA AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15067378 20613959
NR3C1 IL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15826950 18028994
ADRB2 GNA14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7797501 31160049
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
BDKRB1 GRIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
HTR2B OAZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
VDR NPHS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21803771 19474283
MEF2A SLC2A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17317207
BDKRB2 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
VAC14 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CREM PTH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16059773 18460422
GNA14 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
HTR2B ATP1B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
LTB4R2 SLC2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 TMEM11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
APLNR APLN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8294032 9792798
CHRM5 SLC6A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB1 SLC6A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
VDR SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10037600 11278756
AGT AGTR2 â—¼   UP_REGULATES ✅ + 0.81 0.81 Signor 16597412
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC TFAM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
JAK2 AGTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 7746328 11152457
RAB7A CDC42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 31871319
S1PR1 GRIN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACE AGT â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EPOR PLCG1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15953601 15329338 15644415
SMAD4 JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10220381 25609649
AGTR1 CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CAV1 S1PR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10921915 16189514
NR1H3 RXRB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 15604093 33961781 26871637
AGTR1 GRK5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9211925 8662816
GSTA1 GSTA4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRLR JAK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9202403 10772872 20962278
AGTR1 ARRB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11579203 17498700 15611106
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CSF1R PIK3R1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CALM1 CAMK2D â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 RYR3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CALM1 GRIN1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AGT AGTR2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ABL1 JAK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9774693 12130510
ARF6 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11533043 16189514 11867621
RAB7A RAB4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 10329441 16962593
RAB5A RAB7A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NDUFB8 UQCRQ â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
PPARG CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12813462 21690289
RAB7A CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RAB11A RAB5A â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
NDUFA9 UQCRQ â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ADRBK1 GNG2 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CDC42 NCF2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
JAK2 RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9689060 11134016 8876196 10205168
RAB5A AGTR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11682489
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ABL1 PLCG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10708759 1383690 17474147
RXRB PPARG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20211142 22205725 15604093 25609649 30699358
ADRB1 ARRB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10862778 18787115
ABL1 PIK3R1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ARF6 ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11533043 16189514 11867621
SOS2 PLCG1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17474147 10940929
SMAD2 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11371641 20195357 10220381 25609649
SND1 STAT6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12234934 20225206
S1PR1 GNAI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 8626678
RAB11A RAB7A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ADRB2 ARRB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BAK1 BCL2L11 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
GABRA1 GABRB3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CALM1 SLC9A1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
BCL2L11 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22492984 12242151
NCF2 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
ARF6 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
SMAD2 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11804592 28628118 28205554
MYC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 9315742 28628118 28205554
MYC ELK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10918582 18444242 11258956
MYC ADCY9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC S1PR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ACE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPS15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PDGFA PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
AR PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22740037 12063252 20610535
PPP2R5C RAF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
PPP2R5C RAF1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
CALM1 GRK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11042191 8910504 9753452
CALM1 CNGA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7526403 7525588 7678445
CALM1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2022671 7685187 8417150
S1PR1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8626678 31160049
SMAD2 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 25514493 11927552 28443643 21988832 20211142 15467747 12732634 25609649 15922743 12419246 9288972 21454478 19139564 24157709 18729074 22442258 17283070 16916642 15350224 17591701 11274206 15761153 31591477 26555259 9892009 9311995 10085121 9389648 10781087 12167862 10878024 18783722 27703004 18511908 28468752 19135894 10531362 12794086 15231748 21297662 12621041 19917253 11027280 24584437 16751102 31932471 10199400 21532621 12808092 33961781 11264182 11102446 11114293 12543979 23788427 15817471
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
SMAD2 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21990365 17303001 15306544
MAPK11 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 20820849
SMAD3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10903323 11306568 10220381 9732876 21829441
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
JAK2 IL5RA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 2681215 1400495 1396555
JAK2 IL5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 2681215 1400495 1396555
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NCF2 CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7738010 9642115 16189514 11090627
AR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18386814 16317058
STAT6 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17237818
STAT6 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22378047 25934862
SND1 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15695802 12234934
MTNR1A GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17215244 31160049
LPAR2 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15856019 31160049 11093753
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
ADRB2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23208550 24658140 17148612 24561123 27226565
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
GRK2 GNA11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
NR1H3 PPARA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 24713062 15722453 8621574
PPARA NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18758514 12595494 18498712
RXRB NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26871637 32296183 15604093
PPARA SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18037994 15665064 22100307
RXRB PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8384714 23331499 11237216
NR3C1 HTR2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20941551 11174015 7476030
IL5RA IL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7721873 22153509 10823900 7957082 1495999 1732409 10880230
GRK2 GNA15 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
GNA14 GRK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
NDUFB10 NDUFB8 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PLCG1 JAK2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 17474147 14978237
PRKAB2 PRKAG3 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
ACTA2 ACTC1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
GNB3 GNGT2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ADCY9 GNAL â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ELK1 MAPK1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
GNAI1 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
MYD88 IRAK1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 17567694 11544529 33052227 22011580 11960013 16951688 16024789 12538665 12034707 21903422 17920759 31776466 16461741 10383454 21179087 17276401 11976320 17548806 10854325
RAB7A RAB5A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 34079125 22939629 10329441 26344197
ARRB2 AGTR1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 11226259 11279203 15611106 28298427
ADCYAP1 GNG2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CACNA2D1 CACNB2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
NDUFB10 UQCRQ â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
NDUFB9 UQCRQ â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
JAK2 EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 14982882 12441334 11779507 8343951
NDUFB8 NDUFB9 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
CALM1 MYLK â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
IL5 IL5RA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NR1H3 RXRB â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EPOR JAK2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
IRAK1 MYD88 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GNAI1 GNG2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
GNB2L1 RPL18A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL18A RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPL32 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL32 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL32 RPS21 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL32 RPL36 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPL23 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPL36 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPS15 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPL8 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL36 RPS21 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL36 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL8 RPS21 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPS15 RPS21 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL7A RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPS15 RPS20 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPS20 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
GNB2L1 RPS13 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
NDUFB10 NDUFB9 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GNB2L1 RPS21 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPS17 RPS20 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL18A RPS15 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GNB3 GNG13 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NDUFA9 NDUFB9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL18A RPS21 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL32 RPS13 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL32 RPS20 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL36 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GNB2L1 RPL7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL36 RPS20 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL36 RPS13 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL8 RPS17 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL8 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS20 RPS21 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL7A RPS21 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS17 RPS21 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL7A RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL18A RPL36 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL32 RPS15 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23 RPS17 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23 RPS21 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL36 RPS15 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS21 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS15 RPS17 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS17 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS15 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL32 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL32 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL32 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL36 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL8 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL8 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
NDUFA9 NDUFB8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB3 GNG2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL32 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL36 RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS20 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23329794 12637538 16891660 28174535 20841568 12505989 15212693 15024053
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20861316 11113114 12408982
ABL1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19818398 18619508 10637231 20841568 14757045 15302935
ABL1 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 10708759 19290927 12652307 1383690 16525023 8657103 20841568 17474147
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30323259 25368164 26385316
JUN BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17702754 16153157 23285061 22869147 21439021
MAPK1 BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15486195 17604722 14555991 28474232 19150432 12646560 16282323 12818176 17570479 15486085 15212693
KLF4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23884787 11005769 23861801 19737957 10908361 21132436 21224073
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
PPARG CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23455892 18927468 14764597 15486348 11287611 20651819 15041706 19075513 15193259
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
ELK1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 8386592 11145955 7588619 7889942
MAPK1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
MAPK1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12351702 18669648 9199329
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
MAPK1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 25409419 11733495 16574647 9099735 9030579 15507114 26670611 17570479 17998334 18596912
MAPK1 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 17145710 9130707 20506250 15547943 12551925 19690332 9763608 12697810 8007980 16291755 11279280 16393692 17255949 8208531 15014501 10637505 15187187 8586671 19541618 11145955 19565474 11309409 8887554 17052211 9501095 18334532 15782123 8548291 9927426 21655091 7889942 8262053 15655247 8386592 10716983 12665513 15967991 10644696 8477450 12947314 11274345
MAPK1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12801888
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20058876 15253667 25162926 27049728 18669648 17209041 18088087 20068231 11604491 23602949 18701649 23678047 28554535 19415658
MAPK1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19218245 18032789 18729074 16156666 19914161 23331499 19914168 24080014 8226933 14512875 15520018 20736297 26497676 12193595 26297431 18988627 8388392 10197981 15241418 18775330 9604935 9380693
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
MAPK1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10187842
MAPK1 PPP2R5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16456541
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC STAT6 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC TGFB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
PPP2R5D MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
JAK1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9774657 15021914 7544789
EPOR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 7559499 15644415 16713569 24113870 9162069
JAK2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8702385 12706299 16135792 17474147
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CSH1 PRLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 10966654
CALM1 CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
CALM1 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 156362 1519061 6893940 23456740 7947686 6934518
ARRB1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
ARRB2 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
MTNR1A GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10598579 17145710 17215244 31160049
ADORA1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3805010 6305455 6162091 31160049
GNAI3 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933 8327893
GNAI3 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
JAK2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17474147 14978237
PRKD1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19651622 8885868 20068231 1370476
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD2 â—¼   PROTEIN_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD4 ACTA2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD4 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16189514 11160896
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 STAT6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL5RA JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9516124
JAK1 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9852261 23331499 9045682 22661199 22000020 10856136 23124025
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD2 ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20628268 18631173 18065393 17105765
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD2 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11160896
TGFB1 SMAD3 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD3 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 ACTA2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21990365 15306544 17303001 16858008 12702545 24446247 19261809
SMAD3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26553048 27974707 10708950 19214138
SMAD3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 12457461 12524424
NR3C1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12902338 16189514 10518526
TGFB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21557273 24899689 24075003 24485922 28756206 32196115
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
MYD88 IRAK1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
MYD88 IRAK1 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
MYD88 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
MYD88 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 10383454 16951367 12538665 21903422 9430229 12360211 11976320 17228323 19775907 16024789 17276401 17785432 17567694 10854325 10217414 17920759 16461741
JAK2 STAT6 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
PRLR JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 9202403 21071413 17312100 18988627 20962278 11713228 10772872
IL5RA JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 9516124 17312100 11823534 7602114 15795318
JAK2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11134016 8876196 9689060 10205168
JAK2 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9852261 23331499 18852293 22992805
JAK2 EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10660611 12441334 7559499 8343951 18672044 11779507 12027890 11443118 12524467 9030561 9573010 15212693 10579919
TGFB1 PDGFA â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
PPARG TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 14702344 17625041 31023188 17995524 16321227 18615188 14693716 12711314 16611854 18991162
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
TGFB1 PDGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 16474430 17934056 18403754 20519943 16607286 21900405 11133108 14557817 15548370 19920116
JUN RAF1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
MEF2A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12574153 10330170 20590529 9252389 8355696 12016267 19389706 7760790 1406636 10403485 12054430
PPARA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10542237 17360982 18754816 15838301
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN IL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11579103 12452838 10491186 17845581 9234684 7615560 8120390 17687519 7592673 16373364
JUN PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11901151 16001969 19783677 15238218 23523690 10668496 16007171 12057991 22472290 18294142 16339564 17556653 9830045 9988750 19825968 15994313 15772294 9620167 9686761 15525691 11356200 16256955 11234900 18097055 11980644 9705326 19522015 11278336 18282182 12086396 10811116 20237399
JUN MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9334186 15777790 23608488 8957070 1429874 14755151
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
NDUFB8 NDUFA9 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA9 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA9 NDUFB10 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA9 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB8 NDUFA9 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA9 NDUFB10 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB10 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB8 NDUFB10 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB8 NDUFB10 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB10 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PPARG STAT6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARG STAT6 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
PPARG STAT6 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
PPARG SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16670091 12777391 20406953 12777397 16096283
PPARG ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15077315 14702344 20037602 12055599
PPARG NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11604492 16959872 24751522 14703507
PPARG AGTR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20890053 11416035 11409645 16938288 22282354
RXRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22205725 25609649 23331499 20211142 15604093 11237216 18988627 10882139
PPARG SLC2A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18391971 17317207
CYBB NCF2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF2 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
KLF4 PTGS2 â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
NR3C1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10631313 18945810 10827178 18657608 9918831 19797430 10701683 18650268 16198345
PPARA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11840453 12388637 11971025 18648741 11578780 11412039 11007963 20022932 21323895
MAPK11 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 19436832 15140942 20506250 9235954 21614932 16393692 11274345
STAT6 KLF4 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10485906 12223527 12244147 14610620 15634881 23124025 24204259
STAT6 IL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20608912 21276008 11120785 16393972
KLF4 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858008 23646205 22241174 18511453
ADCYAP1 ADCYAP1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 8703026 16930633 12488235 10583729 11931347 21350482 10100920 17470806 8253796
AGT ACE â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 6269175 2846041 1848554 10536878 2558510 12540854 3017438 6270633 1668266 1851160
ACE AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11076943 10969042 23056909 15283675
ADORA2B GNG2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
ADORA2B GNG2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
GNG2 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309
S1PR1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 8626678 31160049
ARRB2 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
ARRB1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
GNAI1 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI1 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9748257 23109003 15539636 7935349 16460834 11376933
MEF2A MAPK11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10805738 9988769 9069290 9858528 10330143
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
ARRB2 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23208550 17148612 17666399 24658140 27226565 2163110 24561123 22364396
GNA11 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309
NR1H3 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20103707 22403301 12970362 12697904
NR1H3 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 24713062 21071413 16189514 14960721 8621574
NR3C1 AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20978123 15630592 17475670 15854165
AGT MAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1282979212829790 12829792
AGT AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12006574 21464395 10193788 10993080 16189514 15930094 9797979 16597412 17346243
AGT AGTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 2775266 21464395 8315512 21542804 17138938 8185599 15930094 9797979 8242249 7850406
NR3C1 RLN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15149733 19289144
NR3C1 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11216640 10329476 9694812
ADRB2 GRK2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8672451 8514797 16687412 2871555
GRK5 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 96278816 20038610 9516468 28431242 8662852 18034461
GRK2 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 96278816 23473322 8662852 10499588 18056263
CAMK2D CACNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20194790
IL5 IL5RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 23331499 1833065 7721873 10823900 1732409 10880230 22528658 7957082 1495999 8567620 11748263 22153509
CGA LHCGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10342833 12727981 1922095
ADM RAMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11693189 30139742 15361343 15692146 12565884 9620797
KLF2 S1PR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16855590 17548599 19592277 17101733 21160050
GRK5 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
VDR PTH â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20558332 9717845 7489414 17095575 8920918
RXRB VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 15604093 10721933
MEF2A KLF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19106103 15988006 19696400 19696221
MEF2A SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19321702 14630949 11718554 17164432 15364617 21233771 18326493 7545962 16105857 18198354 16985263 15111488 22079207 15294043 23899560 12097321 9571041 22496345 24326422 18647882 9603935 12641495
KNG1 BDKRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
KNG1 BDKRB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
KNG1 BDKRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9313952 8856107 8735629 9111052 8063797 10422787
KNG1 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9203620 8063797 8302267 28966616
GNA15 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309
RAMP1 CALCB â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2177866 8626685 2985435 6609312 14722252
ADM2 RAMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21658025 30139742 12684503
CALCB RAMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11693189 962079712234182 12529937 15692146 9620797
GRK2 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
GRK2 ADRA2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19651622 7876239
APLN APLNR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10617103 12939143 11336787 10802050 10777510 12603839 16189514 9792798 15341513
GNA14 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309