Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAX8 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8521821
IKBKE STING1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900850106 19433799
TP53 GMPS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27939741
AGTR1 SAE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
TP53 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16249378
BCL6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15577913
BCL6 ZBTB17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17828269
CRX PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850845 18172122
ESRRG ESRRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17157980 15821111
FH SAE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 GDF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17276395
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
SAE1 TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 15327968 5217177
UBB SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM29 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SUMO2 SAE2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19471022 25027693 32786267 21252943 16620772 21693764
SUMO2 DNM1L â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29128334 23524851 32786267 21693764
UBC9 TRIM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 34508066
SAE2 SUMO3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21518904 25027693 12924945 16189514 16620772
UBC12 SAE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28581483 26344197
MYC FAF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
SUMO3 UBA2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
FAF2 UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 18775313
SUMO2 SAE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 32786267 26496610 16620772
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
SAE1 SUMO3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MYC ZBTB17 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
UBB USP2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
UBC9 SAE2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21518904 33961781 26344197 12641448 17353931 16455490 19250909 26496610 9920803 18691969 28165030 31575873 17643372 28514442
UBC9 SAE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 12641448 17353931 19250909 26496610 15229330 28514442
UBC12 UBA3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 32145688 19250909 10207026 27348078 29547696 15361859 19549727 28475037 30097011 27182664 28581483 18652489 28514442 29973603 15694336
ETV4 AGTR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8206588
TP53 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23852341 19427386
HSPA1A FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
MYC PQBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PAX5 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8521821 22105368 21319196
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 SUMO3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 UBA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 UBD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21396347 18431400
SAE1 UBA2 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
UBC9 SUMO2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25027693 26496610 23871147 24969970 20797634 26344197 30574775 16524884 17938407 16713569 31056421 21693764 19471022 30201799 32786267 12924945 28514442 16189514 21949651 17491593 16620772 22578841 11451954 28784659
SUMO1 SAE1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 15660128 12941704 9920803 12924945 19246003 20164921
SAE1 SUMO2 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
UBC9 SUMO3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21518904 33961781 25027693 11451954 26344197 17353931 16524884 16713569 12924945 28514442 16189514 21949651 16620772
SUMO1 SAE2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21518904 32296183 25416956 14673145 9920803 10217437 12924945 20501649 19246003 16189514 20164921
SAE1 UBE2I â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SUMO1 UBA2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
SAE1 SUMO1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 16494873 16732283 18359863 25502805 10961991 26496610 23871147 26264872 15931224 26344197 9497385 16524884 17938407 9920803 18691969 16713569 9353268 11735126 19684601 21518904 32296183 17353931 8921390 17956732 14673145 19785004 21212807 12924945 22411991 20501649 25416956 16189514 17491593 21949651 21174150 24352468 18264111 18211895
SAE1 SAE2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 15660128 33961781 26344197 17353931 12941704 22939629 26496610 10187858 9920803 10217437 26264872 28514442 22863883 16189514 20164921
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SAE1 UBA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBA2 UBE2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TP53 GDF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17762884 12011055 10618379 17191121 11895857 21586550 10777512 12767058 20230799 17276395 16435911 11994274 17569660
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
MYC ZBTB17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17145710 26766587 18923429 29137325 20426839 11283613 17418410 9312026 20697356 19786833 16352593
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129