MEN1
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
MLST8
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12533512
18046414
|
MTOR
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12533512
18046414
|
SUMO1
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
UBE2I
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
SUMO2
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PIAS4
|
SUMO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
RPTOR
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12533512
18046414
|
ESR1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21920899
23658738
|
NR0B2
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20375098
|
HIF1A
|
SNAI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23979441
23496980
|
STUB1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19940151
25637186
|
PROX1
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18948102
6787391
|
SUMO1
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17036045
5219211
|
SUMO1
|
NRIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18211901
|
SP1
|
YY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22553354
|
YY1
|
BGLAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8990171
10804019
|
YY1
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12533512
18046414
|
FAM9A
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESRRA
|
RNF208
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31862882
|
ESRRA
|
APOA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20889132
15466464
|
PPARGC1A
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12533512
18046414
|
ESR1
|
TFF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
6593703
|
PPARGC1A
|
NR1D1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17476214
|
ESRRA
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18288196
19429439
|
SP1
|
VEGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19147754
|
RBCK1
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPARA
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17275789
22033933
|
ESR1
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
18511507
|
NR0B2
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18385139
16213225
|
ESR1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16144913
|
PPARG
|
ESRRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20519122
15821111
|
PPARG
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11861425
11426586
|
ESR1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16144913
|
HIF1A
|
ESRRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0711677105
18509053
|
HIF1A
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19071119
6802010
|
HIF1A
|
SUMO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7941484
19680224
|
SIRT3
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
21109197
22850421
|
HIF1A
|
KDM2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32938217
|
HIF1A
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17848618
19016748
|
HIF1A
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17426252
23884959
|
HIF1A
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19934262
15780936
|
HIF1A
|
GK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14612449
15134337
|
SP1
|
NRIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22629304
20200160
|
SP1
|
ADH5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9867805
12004059
|
MEF2C
|
RUNX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
HDAC5
|
MEF2C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10737771
11062529
|
NR0B2
|
PDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22698918
21081708
|
ESRRA
|
PNRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214601
11574675
|
ESRRG
|
ESRRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17157980
15821111
|
ESRRA
|
LTF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9286700
10779508
|
ESRRA
|
BGLAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23788330
20417614
|
ESRRA
|
NR2F6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15955695
|
ESRRA
|
MFN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18974884
19448711
|
UBE2I
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
SUMO3
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SUMO3
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11451954
17938407
|
HDAC5
|
MEF2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10748098
15194749
|
HDAC5
|
RUNX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
16613856
|
RXRA
|
GCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11872666
14749268
|
NR0B2
|
GCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14752053
19366697
|
RXRA
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17673910
5223765
|
NCOA3
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17476305
5219902
|
NCOA1
|
BGLAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17218095
17786964
|
NCOA1
|
NRIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10612426
23547260
|
NCOA1
|
ESR1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
5222291
17627277
|
MEF2D
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8798771
9858528
|
ESR1
|
NOS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17921256
0704315104
|
THRA
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11578528
11687272
|
RXRA
|
NRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790787
17684114
|
ESRRG
|
NRIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14645497
16439465
|
NR0B2
|
ESRRG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21459093
8150833
|
NR0B2
|
ESRRG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11705994
19721712
|
ESRRG
|
NR0B2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11705994
14627819
|
RXRA
|
PNRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214601
11574675
|
RXRA
|
BGLAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10677586
7705332
|
NR0B2
|
SCT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16888194
19372104
|
NR0B2
|
THRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11368516
|
NCOA3
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
PPARG
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
18509005
24735796
20360975
22282354
18310298
|
HDAC5
|
MEF2C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
10737771
23752268
11279209
20211142
|
SP1
|
KAT2B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16050810
15647279
|
KAT2B
|
NCOA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
9445475
9346901
9267036
|
HIF1A
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
MEF2B
|
MEF2C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MEF2A
|
MEF2C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25609649
|
NCOA1
|
NCOA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17476305
18267973
|
MEF2B
|
MEF2D
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SUMO2
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21693764
19684601
|
NCOA3
|
NCOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18267973
11971985
|
MEF2B
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
SUMO3
|
UBA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
827.0
|
0.82
|
STRING
|
36370105
|
PNRC2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11574675
15604093
|
ESR1
|
NCOA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
11477071
|
HDAC5
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
NCOA1
|
NCOA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
CYC1
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
SUMO1
|
PIAS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
20016603
15831457
16524884
|
ESR1
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
15961505
|
NCOA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
17627277
5222291
|
ESR1
|
NCOA1
|
â—¼ PROXIMITY
|
✅
|
|
0.84
|
0.84
|
mint
|
17627277
5222291
|
ESR1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9717844
23403292
9121466
|
HIF1A
|
KAT2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
PIAS4
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
PPARG
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
NR0B1
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18381063
15604093
19596656
22843091
|
NRIP1
|
THRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
KAT2B
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22908229
21148070
20620956
16543236
|
ESR1
|
MEN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16651450
31527615
|
PIAS4
|
SUMO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20016603
20696768
15383276
16713569
|
RNF4
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34550526
10617653
21983342
26511642
|
SUMO1
|
SUMO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24654937
25027693
15576338
17938407
21098080
|
SUMO2
|
SAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19471022
32786267
26496610
16620772
25027693
|
NRIP1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8887632
16189514
12549917
|
SAE1
|
SUMO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
PIAS4
|
SUMO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19471022
15383276
16713569
19394292
16524884
32786267
20016603
20696768
21252943
22578841
21693764
|
ESR1
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10681512
17656465
17312152
16651265
18765668
10446910
15084343
16439465
15637147
19652226
15705965
15987735
9611253
15557281
9328340
|
NCOA1
|
NCOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18267973
9774463
11971985
9751728
|
NCOA3
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9267036
16713569
9346901
15863722
11027271
11851396
|
RXRA
|
FUS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32814053
9440806
16713569
|
RXRA
|
THRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
SP1
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
DPF2
|
SMARCD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
SP1
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18239466
18572193
|
NR0B2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9773978
11861507
|
NSD1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
23975195
9628876
31527615
|
NRIP1
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
9626662
10022764
|
PPARA
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
NRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
KAT2B
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9445475
9296499
9223281
|
MEF2A
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19684601
17036045
16484498
|
ESRRA
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
ESRRG
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
NR0B2
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11696534
16189514
19596656
|
HIF1A
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12228247
17024177
17418410
15780936
|
SP1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18270252
10361124
10393239
16713569
|
SAE1
|
SUMO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17353931
12924945
26344197
|
MEF2D
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8798771
33961781
25609649
9858528
20590529
|
NR0B2
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12198243
16189514
21988832
10594021
|
NCOA1
|
THRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
NCOA1
|
KAT2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12163591
10809234
10777539
|
MTOR
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16847060
26522726
12604610
19619545
26348909
33378666
20169205
24036451
18570873
24516643
19299511
34031390
22424946
22356909
25940091
12719976
22544753
23263282
12150926
12665511
18505677
17277771
17461779
22493283
19114562
18722121
21071439
18030348
19446321
12718876
12747827
24375676
22258093
16837165
21045808
16962653
18955708
17565979
12408816
15467718
23953116
27043084
23911927
17043309
31601708
21177249
21614075
21795849
16631613
20381137
21321085
23297343
23872070
16354680
19875983
25446900
29059166
24337580
16603397
16183647
34171383
15066126
24403073
25332233
17386266
19145465
25007995
16798736
26678875
15268862
20427287
30865892
16919458
25273559
15459249
18519641
18504440
12150925
|
SUMO1
|
RNF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29180619
32296183
24907272
15707587
23086935
24151981
24844634
|
RNF4
|
SUMO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26950370
23560854
32733036
32786267
23530056
23086935
22661230
25533185
29180619
20943951
31087003
24969970
32521226
29120074
29549242
18408734
21252943
24151981
24844634
|
SP1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23843607
20160399
23704280
|
NR0B2
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20185821
20375098
21081708
|
SIRT1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15850715
21633182
|
ESR1
|
SUMO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15961505
24119295
18404132
|
SFTPA1
|
SFTPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10781424
11087951
1986781
|
PPARA
|
APOA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19433068
|
RXRA
|
APOA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19433068
|
PPARGC1A
|
NRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
PPARGC1A
|
NRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
PPARGC1A
|
PDK4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
PPARGC1A
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
MEF2C
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18946175
12181572
19553684
|
NCOA1
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16891307
19194461
18511507
|
ESRRA
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23668787
16213225
21625432
|
PPARGC1A
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21775429
10669761
|
NRIP1
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500849
16189514
9626662
19596656
11877444
|
NCOA2
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500849
23178929
15026545
10944516
19596656
11877444
17513608
|
NCOA3
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500849
23178929
10944516
15604093
19596656
35140242
11027271
11877444
15888456
|
PPARG
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23178929
17704298
10944516
15604093
19596656
17312272
10731636
16373399
30595551
17011503
17468099
22070604
15026545
10339548
10347167
9121466
9041124
23975195
20717101
10848596
9744270
17449869
11500849
16713569
11027271
11877444
15888456
17513608
30813326
|
PPARG
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22363753
16189514
12763030
10944516
31547433
30404011
20211142
35140242
25609649
17312272
23703729
7838715
19047629
12966085
22205725
14587029
10882139
30595551
30699358
9065481
21833030
9568716
34081964
21478865
9121466
23275339
17579352
19147680
26260846
16713569
12591919
10854698
30651555
32929351
23711995
11877444
15888456
18217139
19043829
17980149
|
HIF1A
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18461556
19490906
11879638
|
NR0B2
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24038081
16803864
11696534
|
PPARG
|
GK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11872666
14749268
|
HIF1A
|
GCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14612449
15134337
|
SP1
|
LTF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10845904
9666128
|
SP1
|
PCK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14744869
19329064
|
SP1
|
GCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17446237
19411616
17686483
|
SP1
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7541039
|
ESRRA
|
PDK4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
ESRRG
|
PDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17079227
23050013
19690166
|
ESRRA
|
NRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
ESRRA
|
NRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
ESRRA
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16314495
18046414
18048642
|
ESRRA
|
SULT2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21513704
15878968
24038886
|
ESRRA
|
ACADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9271417
12181319
16061943
|
SUMO2
|
SAE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11481243
19107418
11451954
|
HDAC5
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10737771
22308472
10748098
25609649
12626519
|
HDAC5
|
MEF2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10737771
11062529
12896970
|
NCOA1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20608937
15604093
12738788
11003650
11250900
18451880
11867769
15140878
16282588
11165056
11376110
17627277
14715875
10731636
9259327
17363140
11113179
16606617
12630920
9121466
10760302
26487511
23975195
11682626
12714702
9192902
9192892
23874500
11358671
16713569
11014206
10454579
9773983
12554772
9427757
10598586
10409727
9774463
12574227
16957778
|
NCOA1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20682316
21478865
9121466
11124027
15604093
7481822
10454579
10517671
17673910
23975195
11027271
17363140
23602807
15140878
9171239
10082574
11438648
10935544
|
NCOA1
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9407140
9626662
10731636
11698662
12163133
15888456
21775429
|
NRIP1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26153859
9115274
16439465
26166704
23403292
33731348
21182203
7641693
9192902
8887632
|
NCOA3
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26153859
20392877
15383283
14766010
25728767
21182203
15145444
18484708
11376110
14966289
9346901
20181721
26166704
16331275
28844863
11389589
11050174
12630920
19491275
17158759
23403292
12714702
17646391
9192892
11353774
16923966
18645020
16713569
30418174
10490106
9765300
12554772
26487511
|
RUNX2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17350616
|
RXRA
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
NR0B1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
11053406
|
ESR1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
NCOA2
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15657427
9430642
21478865
24561505
11514567
11851396
11981034
17947383
10748178
|
RXRA
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
22205725
7760852
34081964
23711995
10195690
15888456
12562861
|
PPARA
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14751809
16842672
17105827
|
NR0B2
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
11369442
|
RXRA
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
|
RXRA
|
NR0B2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23546875
19111018
15202934
|
NR2F6
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318855
23331499
8119938
|
NR0B2
|
BGLAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24389415
21147283
19594294
|
RNF4
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
ESR1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
HDAC5
|
MEF2D
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
10737771
12896970
20211142
|
RNF4
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
PIAS4
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
ESR1
|
NCOA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.93
|
STRING
|
36370105
|
PPARGC1A
|
ESRRA
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
18074631
|
PPARA
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
UBE2I
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5219915
17491593
|
SUMO1
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
20026589
15876874
24434214
20661221
15465032
17938407
|
NCOA2
|
PPARG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
SUMO1
|
SAE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9920803
20164921
15660128
19246003
12941704
12924945
|
MFN2
|
PARK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
SAE1
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
SUMO3
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
ESR1
|
NR2F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
NCOA2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
14766010
12612084
11250900
12837248
17697320
11376110
9430642
11265755
20348541
19460354
18499756
12630920
12714702
9192892
15657427
11014206
16645043
11937504
12554772
26487511
9774463
|
SAE1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
NCOA1
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
RPTOR
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
24036451
|
MTOR
|
RPTOR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.98
|
0.98
|
mint
|
21045808
8088164
|
SUMO1
|
UBA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
PPARG
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
SAE1
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NCOA2
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NCOA1
|
PPARG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
ESR1
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
MTOR
|
RPTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.98
|
0.98
|
Signor
|
19346248
|
NCOA1
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
ESR1
|
NCOA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
SUMO1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PPARG
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
SUMO2
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
MLST8
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
UBA2
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
SAE1
|
UBA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
SP1
|
KAT2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20130956
20144149
17882273
15647279
|
MTOR
|
MLST8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
ESRRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MLST8
|
ESRRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
MLST8
|
â—¼ SHARES_COMPLEX
|
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
YY1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
PPARGC1A
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
MLST8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
ESRRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MLST8
|
PPARGC1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MLST8
|
PPARGC1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
MLST8
|
â—¼ LOCALISATION
|
✅
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
ESRRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
ESRRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
PPARGC1A
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
YY1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
PPARGC1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
PPARGC1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
ESRRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RPTOR
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
139.0
|
1.0
|
Omnipath
|
15268862
24403073
20427287
22258093
21321085
19446321
15467718
19875983
17461779
12665511
12719976
16631613
21045808
21177249
23911927
24337580
25446900
24516643
18614546
12718876
12747827
16603397
17043309
18519641
22544753
25007995
27043084
19145465
23953116
19619545
16919458
24375676
15459249
16837165
16847060
25332233
12150926
22424946
26348909
12150925
18955708
20381137
22356909
17386266
17565979
18030348
16354680
20169205
19114562
21071439
27329724
35561222
16798736
15809305
22493283
17277771
15661536
16962653
1683716516603397
17604271
18676370
16183647
18505677
23297343
23872070
24036451
15066126
18570873
21614075
18722121
12408816
17599906
|
RPTOR
|
ESRRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
ESRRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
PPARGC1A
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
YY1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
ESRRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
PPARGC1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
PPARGC1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
RPTOR
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
12150925
12777372
15755954
15854902
16469695
16915281
17991864
19299511
19864431
19942859
20484410
22025673
22841746
23087689
26159692
|
SIRT1
|
PPARGC1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
15205477
15744310
15989956
18687677
19590512
19960022
|
SIRT1
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23142079
21633182
19553684
|
SIRT1
|
PPARGC1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15744310
20640476
24003218
19553684
|
SNAI1
|
SNAI2
|
â—¼ UP_REGULATES
|
✅
|
+
|
66.0
|
1.0
|
ACSN
|
10048576
11283614
11708773
12490555
12545156
12668723
14623871
14673164
15111329
15151915
15155580
15181457
15448698
15459715
16001073
16079281
16232121
16510505
16556862
16617148
16716598
16831886
17018611
17055429
17093497
17403902
17490644
17537911
17550342
17563753
17615296
17671186
18172008
18297062
18832382
19208835
19412634
19564415
19597490
19935649
20027199
20702634
20706219
20713526
20731704
21041997
21051859
21159887
21199805
21317430
21577210
21685935
21883379
2191300
22006115
22286765
22406545
22439866
22514743
22796940
22945800
23140366
23869868
8844971
9157999
9618481
|
SNAI1
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11850205
16766568
15955695
11245431
|
SUMO1
|
SAE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
9920803
20164921
19107418
10187858
11481243
20501649
|
UBE2I
|
SUMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
21212807
25416956
16713569
18691969
17938407
11735126
25502805
15931224
26496610
16732283
24352468
17353931
18359863
10666456
21174150
8921390
9353268
12924945
21949651
32296183
16524884
17956732
18264111
12764129
10961991
14673145
19684601
17698038
16494873
31515488
23871147
17491593
|
PPARGC1A
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
YY1
|
ESRRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
YY1
|
ESRRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARGC1A
|
YY1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARGC1A
|
YY1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
YY1
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
YY1
|
PPARGC1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
YY1
|
ESRRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
NRF1
|
CYCS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17099248
2166701
12533512
17273866
16908542
24250222
|
ESR1
|
TFF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
21984905
19858291
11517191
18543253
19935720
17317669
22382029
18414489
17938209
19462000
18322535
22093877
16219765
19933843
16087863
15541729
10037443
22543272
16651411
20422012
23874775
|
SP1
|
TFF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18543253
15987735
15541729
|
ESRRA
|
TFF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16024613
19462000
|
PPARG
|
NR1D1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12821652
15733732
|
HIF1A
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10804084
16110315
16127144
17533374
20427344
20535745
20855962
21051947
21372296
21765015
22006996
22461508
22850421
22988108
23390297
24006507
25043024
25103413
25732824
|
ESR1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16267616
12400015
17272396
18252963
18497067
10866309
19420388
19398483
16249470
14647449
15774498
12208749
10995484
|
HIF1A
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
186.0
|
1.0
|
Omnipath
|
20303950
17085645
22609851
12697836
17557905
15140752
17431122
17486380
11866451
20453883
8756616
18027712
10702253
11678207
19046997
19491109
20127031
20307196
15315159
11359907
18233956
12032158
19502554
9178256
15956714
23060442
11350893
15930297
15207747
19074414
20660740
20489156
17089387
15735682
16506055
9746763
21793044
20436213
22789427
21814878
17053163
18835464
18072084
15983061
11749701
20875806
18432192
18471962
15039660
16750526
17322369
16052307
12433987
21447827
16682453
16971129
21258402
20027628
12542982
17272396
20574527
14712484
16865543
17916562
19664474
23354733
18060642
12570801
9235919
22903062
18563715
12154035
12612059
20599538
18572865
21187066
10837481
16596228
12963476
19828020
15169887
15156561
20232316
16969516
15111179
15342781
15475194
9398602
11001829
11191064
10882714
8387214
15191799
12820439
17413038
19111391
16854277
12509854
23404377
16900513
24347168
18021292
17947829
22771629
18295594
15774498
12205045
17498666
11007955
14699103
21145972
16618748
18322419
16540671
20724477
16778202
9393757
11549290
17065555
15315937
18024476
21343542
15705785
10987301
22306343
23086815
16774940
19420388
15050899
19759417
18289162
10415537
15277220
16818499
16982770
24464787
19238077
23028984
11056102
15838297
16301840
18578647
18702304
19020709
19564336
17461470
16515634
20043814
15806152
19336759
22750006
23185615
17470361
15746177
17889387
18339855
15890092
15663958
17704802
10477681
12052835
15382039
11707426
12855680
12023962
20432243
10611972
19819950
9359410
10640274
12393646
16311927
21435239
16357173
21731766
16543242
17481912
20449875
14602779
17167225
11486006
18294451
22076197
17999410
|
SP1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
19671799
12509426
12560084
16638750
15342781
10910082
19147754
22992725
15217947
15737464
11904305
12429844
15688401
15544046
12615726
11678207
15188178
18021292
15883203
15477724
18454179
23652833
16239639
23369005
8910439
15026340
11007955
12644537
14597566
18575762
11232768
11731421
12482909
12570801
15582599
16540671
16790435
18632621
9264407
10581162
16788159
11040101
21115498
23765166
11060301
22326662
23506169
15613498
15970595
11191053
10816575
12975317
20435036
16949073
11980848
14647449
15302997
9271438
15039660
16982770
11559575
|
HIF1A
|
VEGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7768934
11528470
9278421
17987801
16716598
12080085
10403805
16887934
7539918
1823643
12829734
13130303
15451019
9746763
8943284
15369676
9159130
11901189
22952674
11566883
|
PPARGC1A
|
ESRRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARGC1A
|
ESRRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARGC1A
|
ESRRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16314495
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARGC1A
|
PPARGC1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARG
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16513826
32991581
29182484
|
PPARGC1A
|
ESRRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12181319
18063693
15337744
12522104
32296183
18441008
15100410
|
PPARA
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12941763
16226723
20706641
17261671
18769491
|
PPARG
|
PCK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21406501
20124556
11399762
21450790
7799943
11728630
12560325
9518257
|
PPARG
|
UCP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11829740
8668156
10529360
12807871
11875072
12525499
23554809
32991581
|
PPARG
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15590897
19666848
19732722
16020752
|
PPARG
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16269451
15111490
15908479
11777901
|
PPARG
|
RUNX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12878983
18715135
20589837
12704187
|
RXRA
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
12763030
25609649
20211142
11877444
16504037
17579352
16713569
9065481
22205725
23331499
22363753
10854698
19147680
19043829
12591919
9568716
10882139
10935544
17980149
26260846
21478865
14587029
23711995
9121466
18217139
31547433
7838715
19047629
23275339
21833030
12966085
17312272
11237216
15888456
|
UBE2I
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19692572
15507114
26192107
|
NCOA2
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
11500849
9238002
17513608
21071413
15026545
18988627
18584035
10944516
|
SP1
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12759366
19105596
15722551
18624763
12684688
9614091
10574932
10713142
15061658
12270858
15180995
|
SP1
|
SCT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17875929
15118068
|
SP1
|
MAOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15279563
19401466
14697878
20980443
11956220
11259630
15024015
12855685
|
SP1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12237165
19351845
11345900
21235772
23209644
12429135
18006846
10982795
22622808
15691879
21191649
|
SP1
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9865725
22315456
15072557
|
SP1
|
BGLAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11684680
8055923
12700237
21820092
8910434
|
SP1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24240095
11126367
17689681
|
SP1
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15708372
9154804
14726517
15661808
23662037
|
ESRRA
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19462000
10428965
23680656
18234909
|
ESR1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18234909
11522780
9869301
10428965
12761896
|
RUNX2
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18410224
19903460
20713445
14506237
19259985
19915614
21455926
23644099
9794229
11331591
16670084
16195230
19649655
|
ESR1
|
ESRRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12960079
18174157
20211987
|
ESRRA
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15955695
20351196
9865725
11973645
23340254
19800002
10493499
11850205
|
NR0B2
|
ESRRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
11705994
15604093
|
ESR1
|
LTF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16861234
8873065
10738912
10779508
15525592
8441416
|
HDAC5
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10737771
10748098
11062529
12626519
|
NCOA2
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11387316
12815072
10334992
16908160
11870371
10334993
16541101
|
NCOA1
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11698662
10731636
9626662
12163133
21775429
15888456
9407140
|
NCOA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
18451880
9192892
16957778
11014206
16713569
17627277
23975195
15140878
15604093
12738788
17363140
11003650
10454579
16606617
26487511
11165056
10760302
10731636
12630920
14715875
9773983
9427757
9121466
20608937
12714702
9259327
9192902
11358671
10598586
12574227
11113179
12554772
11682626
9774463
|
ESR1
|
NRIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20200160
10379892
16391242
22071320
18414489
|
ESR1
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22052999
11029009
10690351
14742696
19914929
|
ESR1
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19462000
20351196
19605792
11973645
16885386
19282383
19250199
12839940
|
ESR1
|
NRF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18048642
21486948
23892277
|
NRIP1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9192902
23331499
8887632
9115274
7641693
26166704
12554755
26153859
21182203
16439465
|
NR0B2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
21071413
9773978
18988627
11861507
|
ESR1
|
NCOA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
18499756
9192892
9430642
11014206
19460354
15657427
23331499
11477071
26487511
16645043
12612084
20348541
12630920
14766010
17697320
11937504
12714702
12554772
9774463
|
NRIP1
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23331499
10022764
9626662
16189514
9774688
|
RXRA
|
NCOA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11387316
12815072
10334992
16908160
11870371
10334993
16541101
|
NCOA2
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
12612084
11981034
15657427
23331499
21071413
9430642
10748178
11514567
18988627
11851396
17947383
|
NR0B2
|
ESRRG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11705994
23331499
14963109
20516075
21459093
|
NR0B1
|
ESRRG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16314306
15604093
25416956
|
PPARA
|
UCP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11050084
10529360
11875072
19194461
10873645
|
RXRA
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
10195690
12562861
16189514
11237216
10708554
|
THRA
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11018031
23331499
15604093
1331778
1314167
19422879
11117530
16189514
|
NR0B2
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21988832
23331499
16189514
12198243
10594021
|
NR2F1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1311101
23331499
10900149
|
NR0B2
|
PCK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15358835
20688914
18505831
18459945
19720831
17094771
22977252
12324453
|
NR0B2
|
PCK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15047713
15358835
20688914
18459945
17909097
17094771
|
RUNX2
|
IBSP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20947160
12750290
22492284
14667142
17956871
23485603
19324883
11283267
17352650
16000302
10027904
18459139
|
NRF1
|
PPARGC1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20561910
22586274
17360356
21054343
|
NR2F1
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15955695
11973645
11850205
|